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Aliases for TRIM49C Gene

Aliases for TRIM49C Gene

  • Tripartite Motif Containing 49C 2 3
  • Tripartite Motif-Containing Protein 49-Like Protein 2 3 4
  • Tripartite Motif Containing 49-Like 2 2 3
  • TRIM49L2 3 4
  • Tripartite Motif-Containing Protein LOC642612 3

External Ids for TRIM49C Gene

Previous HGNC Symbols for TRIM49C Gene

  • TRIM49L2

Previous GeneCards Identifiers for TRIM49C Gene

  • GC11P089768

Summaries for TRIM49C Gene

GeneCards Summary for TRIM49C Gene

TRIM49C (Tripartite Motif Containing 49C) is a Protein Coding gene. An important paralog of this gene is TRIM77.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRIM49C Gene

Genomics for TRIM49C Gene

Genomic Location for TRIM49C Gene

90,030,149 bp from pter
90,042,029 bp from pter
11,881 bases
Plus strand

Genomic View for TRIM49C Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TRIM49C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRIM49C Gene

No data available for Regulatory Elements for TRIM49C Gene

Proteins for TRIM49C Gene

  • Protein details for TRIM49C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Tripartite motif-containing protein 49C
    Protein Accession:
    Secondary Accessions:
    • A0AVR7
    • A0AVR9
    • Q6DJV1
    • Q9NS80

    Protein attributes for TRIM49C Gene

    452 amino acids
    Molecular mass:
    52933 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRIM49C Gene

Proteomics data for TRIM49C Gene at MOPED

Post-translational modifications for TRIM49C Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TRIM49C Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TRIM49C Gene

Domains & Families for TRIM49C Gene

Gene Families for TRIM49C Gene

Protein Domains for TRIM49C Gene

Suggested Antigen Peptide Sequences for TRIM49C Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 B30.2/SPRY domain.
  • Contains 1 B box-type zinc finger.
  • Contains 1 B30.2/SPRY domain.
  • Contains 1 B box-type zinc finger.
  • Contains 1 RING-type zinc finger.
genes like me logo Genes that share domains with TRIM49C: view

Function for TRIM49C Gene

Gene Ontology (GO) - Molecular Function for TRIM49C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with TRIM49C: view

Animal Model Products

CRISPR Products

miRNA for TRIM49C Gene

miRTarBase miRNAs that target TRIM49C

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for TRIM49C Gene

Localization for TRIM49C Gene

Gene Ontology (GO) - Cellular Components for TRIM49C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
genes like me logo Genes that share ontologies with TRIM49C: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for TRIM49C Gene

Pathways & Interactions for TRIM49C Gene

SuperPathways for TRIM49C Gene

No Data Available

Gene Ontology (GO) - Biological Process for TRIM49C Gene


No data available for Pathways by source and SIGNOR curated interactions for TRIM49C Gene

Drugs & Compounds for TRIM49C Gene

No Compound Related Data Available

Transcripts for TRIM49C Gene

mRNA/cDNA for TRIM49C Gene

(2) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TRIM49C

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRIM49C Gene

No ASD Table

Relevant External Links for TRIM49C Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TRIM49C Gene

mRNA expression in normal human tissues for TRIM49C Gene

mRNA differential expression in normal tissues according to GTEx for TRIM49C Gene

This gene is overexpressed in Testis (x39.9) and Brain - Substantia nigra (x7.2).

SOURCE GeneReport for Unigene cluster for TRIM49C Gene Hs.740080

genes like me logo Genes that share expression patterns with TRIM49C: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for TRIM49C Gene

Orthologs for TRIM49C Gene

This gene was present in the common ancestor of chordates.

Orthologs for TRIM49C Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia LOC485140 35
  • 64.07 (n)
  • 50.46 (a)
(Pan troglodytes)
Mammalia TRIM48 35
  • 98.97 (n)
  • 97.79 (a)
-- 36
  • 98 (a)
-- 36
  • 97 (a)
-- 36
  • 98 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 33 (a)
-- 36
  • 28 (a)
-- 36
  • 28 (a)
-- 36
  • 29 (a)
-- 36
  • 21 (a)
-- 36
  • 28 (a)
-- 36
  • 29 (a)
-- 36
  • 29 (a)
-- 36
  • 29 (a)
-- 36
  • 26 (a)
-- 36
  • 24 (a)
-- 36
  • 29 (a)
-- 36
  • 30 (a)
-- 36
  • 28 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 17 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 27 (a)
-- 36
  • 29 (a)
-- 36
  • 19 (a)
-- 36
  • 21 (a)
-- 36
  • 23 (a)
-- 36
  • 24 (a)
-- 36
  • 28 (a)
(Danio rerio)
Actinopterygii trim109 36
  • 20 (a)
Species with no ortholog for TRIM49C:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TRIM49C Gene

Gene Tree for TRIM49C (if available)
Gene Tree for TRIM49C (if available)

Paralogs for TRIM49C Gene Pseudogenes for TRIM49C Gene

genes like me logo Genes that share paralogs with TRIM49C: view

Variants for TRIM49C Gene

Sequence variations from dbSNP and Humsavar for TRIM49C Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs476481 -- 90,030,671(+) CCAGC(A/G)CAGAT upstream-variant-2KB, intron-variant
rs477510 -- 90,030,814(+) TCCTT(C/G)TATTT upstream-variant-2KB, intron-variant
rs500587 -- 90,030,953(+) ACTTA(A/G)GACCT upstream-variant-2KB, intron-variant
rs521278 -- 90,039,210(-) cgggc(A/G)cggtg intron-variant
rs545018 -- 90,038,944(+) agaca(C/G)cgtct intron-variant

Variation tolerance for TRIM49C Gene

Gene Damage Index Score: 1.62; 31.15% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TRIM49C Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for TRIM49C Gene

Disorders for TRIM49C Gene

Relevant External Links for TRIM49C

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with TRIM49C: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TRIM49C Gene

Publications for TRIM49C Gene

  1. Identification of a genomic reservoir for new TRIM genes in primate genomes. (PMID: 22144910) Han K. … Sawyer S.L. (PLoS Genet. 2011) 67
  2. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 67
  3. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 67
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 67

Products for TRIM49C Gene

Sources for TRIM49C Gene

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