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Aliases for TRIM49C Gene

Aliases for TRIM49C Gene

  • Tripartite Motif Containing 49C 2 3
  • Tripartite Motif-Containing Protein 49-Like Protein 2 3 4
  • Tripartite Motif Containing 49-Like 2 2 3
  • TRIM49L2 3 4
  • Tripartite Motif-Containing Protein LOC642612 3
  • Tripartite Motif-Containing Protein 49C 3

External Ids for TRIM49C Gene

Previous Symbols for TRIM49C Gene

  • TRIM49L2

Summaries for TRIM49C Gene

GeneCards Summary for TRIM49C Gene

TRIM49C (Tripartite Motif Containing 49C) is a Protein Coding gene. An important paralog of this gene is TRIM77.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRIM49C Gene

Genomics for TRIM49C Gene

Genomic Location for TRIM49C Gene

Start:
90,031,106 bp from pter
End:
90,042,025 bp from pter
Size:
10,920 bases
Orientation:
Plus strand

Genomic View for TRIM49C Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TRIM49C Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRIM49C Gene

No data available for Regulatory Elements for TRIM49C Gene

Proteins for TRIM49C Gene

  • Protein details for TRIM49C Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0CI26-TR49C_HUMAN
    Recommended name:
    Tripartite motif-containing protein 49C
    Protein Accession:
    P0CI26
    Secondary Accessions:
    • A0AVR7
    • A0AVR9
    • Q6DJV1
    • Q9NS80

    Protein attributes for TRIM49C Gene

    Size:
    452 amino acids
    Molecular mass:
    52933 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRIM49C Gene

Proteomics data for TRIM49C Gene at MOPED

Post-translational modifications for TRIM49C Gene

No Post-translational modifications

Other Protein References for TRIM49C Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TRIM49C Gene

Domains for TRIM49C Gene

Gene Families for TRIM49C Gene

HGNC:
  • RNF :RING-type (C3HC4) zinc fingers
  • TRIM :Tripartite motif containing / Tripartite motif containing

Protein Domains for TRIM49C Gene

UniProtKB/Swiss-Prot:

TR49C_HUMAN
Domain:
  • Contains 1 B30.2/SPRY domain.:
    • P0CI26
Similarity:
  • Contains 1 B box-type zinc finger.:
    • P0CI26
  • Contains 1 RING-type zinc finger.:
    • P0CI26
genes like me logo Genes that share domains with TRIM49C: view

Function for TRIM49C Gene

Gene Ontology (GO) - Molecular Function for TRIM49C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003677 DNA binding --
GO:0005515 protein binding --
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with TRIM49C: view

miRNA for TRIM49C Gene

miRTarBase miRNAs that target TRIM49C

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for TRIM49C Gene

Localization for TRIM49C Gene

Gene Ontology (GO) - Cellular Components for TRIM49C Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
genes like me logo Genes that share ontologies with TRIM49C: view

Pathways for TRIM49C Gene

SuperPathways for TRIM49C Gene

No Data Available

Gene Ontology (GO) - Biological Process for TRIM49C Gene

None

No data available for Pathways by source for TRIM49C Gene

Transcripts for TRIM49C Gene

mRNA/cDNA for TRIM49C Gene

(2) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TRIM49C Gene

No ASD Table

Relevant External Links for TRIM49C Gene

GeneLoc Exon Structure for
TRIM49C
ECgene alternative splicing isoforms for
TRIM49C

Expression for TRIM49C Gene

mRNA expression in normal human tissues for TRIM49C Gene

mRNA differential expression in normal tissues according to GTEx for TRIM49C Gene

This gene is overexpressed in Testis (39.9) and Brain - Substantia nigra (7.2).

SOURCE GeneReport for Unigene cluster for TRIM49C Gene Hs.740080

genes like me logo Genes that share expressions with TRIM49C: view

Orthologs for TRIM49C Gene

This gene was present in the common ancestor of chordates.

Orthologs for TRIM49C Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia -- 37
  • 98 (a)
ManyToMany
-- 37
  • 97 (a)
ManyToMany
-- 37
  • 98 (a)
ManyToMany
TRIM48 36
  • 98.97 (n)
  • 97.79 (a)
dog
(Canis familiaris)
Mammalia LOC485140 36
  • 64.07 (n)
  • 50.46 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 33 (a)
ManyToMany
-- 37
  • 28 (a)
ManyToMany
-- 37
  • 28 (a)
ManyToMany
-- 37
  • 29 (a)
ManyToMany
-- 37
  • 21 (a)
ManyToMany
-- 37
  • 28 (a)
ManyToMany
-- 37
  • 29 (a)
ManyToMany
-- 37
  • 29 (a)
ManyToMany
-- 37
  • 29 (a)
ManyToMany
-- 37
  • 26 (a)
ManyToMany
-- 37
  • 24 (a)
ManyToMany
-- 37
  • 29 (a)
ManyToMany
-- 37
  • 30 (a)
ManyToMany
-- 37
  • 28 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 17 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 27 (a)
ManyToMany
-- 37
  • 29 (a)
ManyToMany
-- 37
  • 19 (a)
ManyToMany
-- 37
  • 21 (a)
ManyToMany
-- 37
  • 23 (a)
ManyToMany
-- 37
  • 24 (a)
ManyToMany
-- 37
  • 28 (a)
ManyToMany
zebrafish
(Danio rerio)
Actinopterygii trim109 37
  • 20 (a)
ManyToMany
Species with no ortholog for TRIM49C:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TRIM49C Gene

ENSEMBL:
Gene Tree for TRIM49C (if available)
TreeFam:
Gene Tree for TRIM49C (if available)

Paralogs for TRIM49C Gene

Pseudogenes.org Pseudogenes for TRIM49C Gene

genes like me logo Genes that share paralogs with TRIM49C: view

Variants for TRIM49C Gene

Sequence variations from dbSNP and Humsavar for TRIM49C Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs476481 -- 90,030,671(+) CCAGC(A/G)CAGAT upstream-variant-2KB
rs521278 -- 90,039,210(-) cgggc(A/G)cggtg intron-variant
rs545018 -- 90,038,944(+) agaca(C/G)cgtct intron-variant
rs562358 -- 90,034,704(-) gttta(C/T)ctaca intron-variant
rs586873 -- 90,035,699(+) ATTAG(A/G)TAAAG intron-variant

Relevant External Links for TRIM49C Gene

HapMap Linkage Disequilibrium report
TRIM49C

No data available for Structural Variations from Database of Genomic Variants (DGV) for TRIM49C Gene

Disorders for TRIM49C Gene

No disorders were found for TRIM49C Gene.

No data available for UniProtKB/Swiss-Prot for TRIM49C Gene

Publications for TRIM49C Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 3 4
  3. Identification of a genomic reservoir for new TRIM genes in primate genomes. (PMID: 22144910) Han K. … Sawyer S.L. (PLoS Genet. 2011) 3
  4. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for TRIM49C Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate TRIM49C
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for TRIM49C
    • Block miRNA regulation of TRIM49C using miScript Target Protectors

    Sources for TRIM49C Gene

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