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Aliases for TRIM47 Gene

Aliases for TRIM47 Gene

  • Tripartite Motif Containing 47 2 3 5
  • Gene Overexpressed In Astrocytoma Protein 3 4
  • RING Finger Protein 100 3 4
  • RNF100 3 4
  • GOA 3 4
  • Tripartite Motif-Containing Protein 47 3
  • Tripartite Motif-Containing 47 2

External Ids for TRIM47 Gene

Previous GeneCards Identifiers for TRIM47 Gene

  • GC17M076896
  • GC17M074334
  • GC17M074468
  • GC17M074469
  • GC17M071381
  • GC17M073870
  • GC17M069295

Summaries for TRIM47 Gene

GeneCards Summary for TRIM47 Gene

TRIM47 (Tripartite Motif Containing 47) is a Protein Coding gene. Diseases associated with TRIM47 include Astrocytoma. An important paralog of this gene is TRIM25.

Additional gene information for TRIM47 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRIM47 Gene

Genomics for TRIM47 Gene

Regulatory Elements for TRIM47 Gene

Enhancers for TRIM47 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17H075872 1.8 FANTOM5 Ensembl ENCODE dbSUPER 11 +5.3 5283 2 FOXA2 MLX ARID4B DMAP1 TCF12 SLC30A9 PAF1 SP5 ZHX2 MXD4 FBF1 MFSD11 ENSG00000266980 TRIM47 TRIM65 METTL23 NUP85 ENSG00000267801 WBP2
GH17H076258 2 FANTOM5 Ensembl ENCODE dbSUPER 9.9 -389.4 -389376 19 DMAP1 YY1 ZNF143 SP3 ZC3H11A NFYC MEF2D ZNF610 ZNF585B GLIS1 UNK ENSG00000267342 SRSF2 TRIM65 ENSG00000266980 ENSG00000267546 EXOC7 RNF157 MFSD11 PRPSAP1
GH17H075852 1.7 FANTOM5 ENCODE dbSUPER 11.6 +23.7 23717 4 HDGF PKNOX1 FOXA2 MLX ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1 UNK TRIM65 ENSG00000267342 SRSF2 MFSD11 FBF1 CDK3 TRIM47 ENSG00000266980 NUP85
GH17H075875 1.4 ENCODE dbSUPER 13.9 +1.4 1376 4 HDGF FOXA2 MLX ARNT ZFP64 ARID4B SIN3A DMAP1 YY1 SLC30A9 FBF1 TRIM65 TRIM47 ACOX1 ENSG00000267801
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TRIM47 on UCSC Golden Path with GeneCards custom track

Promoters for TRIM47 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000098469 500 1801 HDGF MLX ARNT ZFP64 ARID4B SIN3A DMAP1 SLC30A9 ZNF143 FOS

Genomic Location for TRIM47 Gene

75,874,161 bp from pter
75,878,600 bp from pter
4,440 bases
Minus strand

Genomic View for TRIM47 Gene

Genes around TRIM47 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRIM47 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRIM47 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRIM47 Gene

Proteins for TRIM47 Gene

  • Protein details for TRIM47 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Tripartite motif-containing protein 47
    Protein Accession:
    Secondary Accessions:
    • Q96AD0
    • Q96GU5
    • Q9BRN7

    Protein attributes for TRIM47 Gene

    638 amino acids
    Molecular mass:
    69532 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TRIM47 Gene


neXtProt entry for TRIM47 Gene

Post-translational modifications for TRIM47 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TRIM47 Gene

No data available for DME Specific Peptides for TRIM47 Gene

Domains & Families for TRIM47 Gene

Gene Families for TRIM47 Gene

Suggested Antigen Peptide Sequences for TRIM47 Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the TRIM/RBCC family.
  • Belongs to the TRIM/RBCC family.
genes like me logo Genes that share domains with TRIM47: view

Function for TRIM47 Gene

Phenotypes From GWAS Catalog for TRIM47 Gene

Gene Ontology (GO) - Molecular Function for TRIM47 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008270 zinc ion binding IEA --
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with TRIM47: view
genes like me logo Genes that share phenotypes with TRIM47: view

Animal Model Products

CRISPR Products

miRNA for TRIM47 Gene

miRTarBase miRNAs that target TRIM47

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for TRIM47
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TRIM47 Gene

Localization for TRIM47 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TRIM47 Gene

Cytoplasm. Nucleus.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for TRIM47 gene
Compartment Confidence
nucleus 5
cytosol 5

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for TRIM47 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005737 cytoplasm IEA --
GO:0005829 cytosol IDA --
genes like me logo Genes that share ontologies with TRIM47: view

Pathways & Interactions for TRIM47 Gene

SuperPathways for TRIM47 Gene

No Data Available

Gene Ontology (GO) - Biological Process for TRIM47 Gene


No data available for Pathways by source and SIGNOR curated interactions for TRIM47 Gene

Drugs & Compounds for TRIM47 Gene

No Compound Related Data Available

Transcripts for TRIM47 Gene

Unigene Clusters for TRIM47 Gene

Tripartite motif containing 47:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for TRIM47
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for TRIM47 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b
SP1: - -
SP2: -

Relevant External Links for TRIM47 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TRIM47 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TRIM47 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for TRIM47 Gene

This gene is overexpressed in Breast (25.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for TRIM47 Gene

Protein tissue co-expression partners for TRIM47 Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of TRIM47 Gene:


SOURCE GeneReport for Unigene cluster for TRIM47 Gene:


mRNA Expression by UniProt/SwissProt for TRIM47 Gene:

Tissue specificity: Low expression in most tissues. Higher expression in kidney tubular cells. Overexpressed in astrocytoma tumor cells.

Evidence on tissue expression from TISSUES for TRIM47 Gene

  • Lung(4.3)
  • Pancreas(4.2)
  • Liver(4.1)
  • Nervous system(2.5)
genes like me logo Genes that share expression patterns with TRIM47: view

Primer Products

No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRIM47 Gene

Orthologs for TRIM47 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TRIM47 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia TRIM47 33 34
  • 99.01 (n)
(Bos Taurus)
Mammalia TRIM47 33 34
  • 88.23 (n)
(Canis familiaris)
Mammalia TRIM47 33 34
  • 87.77 (n)
(Rattus norvegicus)
Mammalia Trim47 33
  • 85.79 (n)
(Mus musculus)
Mammalia Trim47 33 16 34
  • 83.7 (n)
(Monodelphis domestica)
Mammalia TRIM47 34
  • 77 (a)
(Ornithorhynchus anatinus)
Mammalia TRIM47 34
  • 59 (a)
(Gallus gallus)
Aves TRIM47 33 34
  • 65.16 (n)
(Anolis carolinensis)
Reptilia TRIM47 34
  • 55 (a)
(Danio rerio)
Actinopterygii zgc:153258 34
  • 23 (a)
Species where no ortholog for TRIM47 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TRIM47 Gene

Gene Tree for TRIM47 (if available)
Gene Tree for TRIM47 (if available)

Paralogs for TRIM47 Gene

Paralogs for TRIM47 Gene

genes like me logo Genes that share paralogs with TRIM47: view

Variants for TRIM47 Gene

Sequence variations from dbSNP and Humsavar for TRIM47 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs1000526359 -- 75,877,053(+) CTCTG(-/ACAGGAGGCCTAGT)ACAGG intron-variant
rs1000545846 -- 75,880,013(+) CTCCC(-/AAA)AAAGT downstream-variant-500B, upstream-variant-2KB
rs1000649482 -- 75,879,584(+) ATAAT(-/GTTAA)GTTAA upstream-variant-2KB
rs1000773585 -- 75,874,183(+) GTTTA(C/T)TGAGC utr-variant-3-prime
rs1001227274 -- 75,873,988(+) AGTGG(A/G)GGTGC downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for TRIM47 Gene

Variant ID Type Subtype PubMed ID
nsv510728 CNV deletion 20534489
nsv833545 CNV gain 17160897

Variation tolerance for TRIM47 Gene

Residual Variation Intolerance Score: 43.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 8.10; 84.52% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TRIM47 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TRIM47 Gene

Disorders for TRIM47 Gene

MalaCards: The human disease database

(1) MalaCards diseases for TRIM47 Gene - From: GeneCards

Disorder Aliases PubMed IDs
  • astrocytic tumor
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for TRIM47

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with TRIM47: view

No data available for UniProtKB/Swiss-Prot and Genatlas for TRIM47 Gene

Publications for TRIM47 Gene

  1. Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium. (PMID: 21681796) Fornage M … Launer LJ (Annals of neurology 2011) 3 45 60
  2. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PMID: 16964243) Beausoleil SA … Gygi SP (Nature biotechnology 2006) 3 4 60
  3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen JV … Mann M (Cell 2006) 3 4 60
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60
  5. GOA, a novel gene encoding a ring finger B-box coiled-coil protein, is overexpressed in astrocytoma. (PMID: 11511098) Vandeputte DA … Hulsebos TJ (Biochemical and biophysical research communications 2001) 3 4 60

Products for TRIM47 Gene

Sources for TRIM47 Gene

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