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Aliases for TRIM47 Gene

Aliases for TRIM47 Gene

  • Tripartite Motif Containing 47 2 3 5
  • Gene Overexpressed In Astrocytoma Protein 3 4
  • Tripartite Motif-Containing 47 2 3
  • RING Finger Protein 100 3 4
  • RNF100 3 4
  • GOA 3 4

External Ids for TRIM47 Gene

Previous GeneCards Identifiers for TRIM47 Gene

  • GC17M076896
  • GC17M074334
  • GC17M074468
  • GC17M074469
  • GC17M071381
  • GC17M073870
  • GC17M069295

Summaries for TRIM47 Gene

GeneCards Summary for TRIM47 Gene

TRIM47 (Tripartite Motif Containing 47) is a Protein Coding gene. Diseases associated with TRIM47 include astrocytoma. An important paralog of this gene is TRIM16L.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRIM47 Gene

Genomics for TRIM47 Gene

Regulatory Elements for TRIM47 Gene

Enhancers for TRIM47 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around TRIM47 on UCSC Golden Path with GeneCards custom track

Promoters for TRIM47 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around TRIM47 on UCSC Golden Path with GeneCards custom track

Genomic Location for TRIM47 Gene

75,874,161 bp from pter
75,878,600 bp from pter
4,440 bases
Minus strand

Genomic View for TRIM47 Gene

Genes around TRIM47 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRIM47 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRIM47 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRIM47 Gene

Proteins for TRIM47 Gene

  • Protein details for TRIM47 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Tripartite motif-containing protein 47
    Protein Accession:
    Secondary Accessions:
    • Q96AD0
    • Q96GU5
    • Q9BRN7

    Protein attributes for TRIM47 Gene

    638 amino acids
    Molecular mass:
    69532 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TRIM47 Gene


neXtProt entry for TRIM47 Gene

Proteomics data for TRIM47 Gene at MOPED

Post-translational modifications for TRIM47 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TRIM47 Gene

No data available for DME Specific Peptides for TRIM47 Gene

Domains & Families for TRIM47 Gene

Gene Families for TRIM47 Gene

Suggested Antigen Peptide Sequences for TRIM47 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 B30.2/SPRY domain.
  • Belongs to the TRIM/RBCC family.
  • Contains 1 B box-type zinc finger.
  • Contains 1 B30.2/SPRY domain.
  • Belongs to the TRIM/RBCC family.
  • Contains 1 B box-type zinc finger.
  • Contains 1 RING-type zinc finger.
genes like me logo Genes that share domains with TRIM47: view

Function for TRIM47 Gene

genes like me logo Genes that share phenotypes with TRIM47: view

Animal Model Products

miRNA for TRIM47 Gene

miRTarBase miRNAs that target TRIM47

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TRIM47 Gene

Localization for TRIM47 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TRIM47 Gene

Cytoplasm. Nucleus.

Subcellular locations from

Jensen Localization Image for TRIM47 Gene COMPARTMENTS Subcellular localization image for TRIM47 gene
Compartment Confidence
nucleus 5
cytosol 3

Gene Ontology (GO) - Cellular Components for TRIM47 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IDA --
genes like me logo Genes that share ontologies with TRIM47: view

Pathways & Interactions for TRIM47 Gene

SuperPathways for TRIM47 Gene

No Data Available

Gene Ontology (GO) - Biological Process for TRIM47 Gene


No data available for Pathways by source and SIGNOR curated interactions for TRIM47 Gene

Drugs & Compounds for TRIM47 Gene

No Compound Related Data Available

Transcripts for TRIM47 Gene

Unigene Clusters for TRIM47 Gene

Tripartite motif containing 47:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TRIM47 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6a · 6b
SP1: - -
SP2: -

Relevant External Links for TRIM47 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TRIM47 Gene

mRNA expression in normal human tissues for TRIM47 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for TRIM47 Gene

This gene is overexpressed in Breast (25.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for TRIM47 Gene

SOURCE GeneReport for Unigene cluster for TRIM47 Gene Hs.293660

mRNA Expression by UniProt/SwissProt for TRIM47 Gene

Tissue specificity: Low expression in most tissues. Higher expression in kidney tubular cells. Overexpressed in astrocytoma tumor cells.
genes like me logo Genes that share expression patterns with TRIM47: view

Protein tissue co-expression partners for TRIM47 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA differential expression in normal tissues for TRIM47 Gene

Orthologs for TRIM47 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TRIM47 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia TRIM47 35
  • 88.23 (n)
  • 91.05 (a)
TRIM47 36
  • 91 (a)
(Canis familiaris)
Mammalia TRIM47 35
  • 87.77 (n)
  • 89.32 (a)
TRIM47 36
  • 61 (a)
(Mus musculus)
Mammalia Trim47 35
  • 83.7 (n)
  • 88.56 (a)
Trim47 16
Trim47 36
  • 88 (a)
(Pan troglodytes)
Mammalia TRIM47 35
  • 99.01 (n)
  • 99.06 (a)
TRIM47 36
  • 98 (a)
(Rattus norvegicus)
Mammalia Trim47 35
  • 85.79 (n)
  • 90.44 (a)
(Monodelphis domestica)
Mammalia TRIM47 36
  • 77 (a)
(Ornithorhynchus anatinus)
Mammalia TRIM47 36
  • 59 (a)
(Gallus gallus)
Aves TRIM47 35
  • 65.16 (n)
  • 57.06 (a)
TRIM47 36
  • 53 (a)
(Anolis carolinensis)
Reptilia TRIM47 36
  • 55 (a)
(Danio rerio)
Actinopterygii zgc:153258 36
  • 23 (a)
Species with no ortholog for TRIM47:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TRIM47 Gene

Gene Tree for TRIM47 (if available)
Gene Tree for TRIM47 (if available)

Paralogs for TRIM47 Gene

Paralogs for TRIM47 Gene

genes like me logo Genes that share paralogs with TRIM47: view

Variants for TRIM47 Gene

Sequence variations from dbSNP and Humsavar for TRIM47 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs1047043 - 75,874,901(-) GGCCG(A/C)AGACT reference, missense
rs1055129 -- 75,876,867(-) CCGAG(C/T)GTAGG intron-variant
rs1063138 -- 75,874,279(-) CACTT(C/T)TGGGA utr-variant-3-prime
rs1105917 -- 75,877,575(+) GGAAC(C/T)CCGCG intron-variant
rs4072479 -- 75,878,057(-) CCCGC(C/G)CTCCG upstream-variant-2KB, reference, synonymous-codon, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for TRIM47 Gene

Variant ID Type Subtype PubMed ID
dgv3264n71 CNV Loss 21882294
nsv908804 CNV Loss 21882294
dgv3267n71 CNV Loss 21882294
nsv833545 CNV Gain 17160897
nsv908820 CNV Loss 21882294
nsv510728 CNV Loss 20534489
nsv908821 CNV Loss 21882294
nsv908822 CNV Loss 21882294
nsv908823 CNV Loss 21882294

Variation tolerance for TRIM47 Gene

Residual Variation Intolerance Score: 43.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 8.10; 84.52% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for TRIM47 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TRIM47 Gene

Disorders for TRIM47 Gene

MalaCards: The human disease database

(1) MalaCards diseases for TRIM47 Gene - From: GeneCards

Disorder Aliases PubMed IDs
  • astrocytic tumor
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for TRIM47

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with TRIM47: view

No data available for UniProtKB/Swiss-Prot and Genatlas for TRIM47 Gene

Publications for TRIM47 Gene

  1. Genome-wide association studies of cerebral white matter lesion burden: the CHARGE consortium. (PMID: 21681796) Fornage M. … Launer L.J. (Ann. Neurol. 2011) 3 48 67
  2. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3
  3. Systematic analysis of dimeric E3-RING interactions reveals increased combinatorial complexity in human ubiquitination networks. (PMID: 22493164) Woodsmith J. … Sanderson C.M. (Mol. Cell Proteomics 2012) 3
  4. A high-throughput approach for measuring temporal changes in the interactome. (PMID: 22863883) Kristensen A.R. … Foster L.J. (Nat. Methods 2012) 3
  5. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PMID: 21832049) OlA!h J. … OvA!di J. (J. Biol. Chem. 2011) 3

Products for TRIM47 Gene

Sources for TRIM47 Gene