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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TRIM45 Gene

protein-coding   GIFtS: 43
GCID: GC01M117654

Tripartite Motif Containing 45

(Previous name: tripartite motif-containing 45)
  Search for TRIM45
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Tripartite Motif Containing 451 2
Tripartite Motif-Containing 451 2
RING Finger Protein 992 3
RNF992 3
Tripartite Motif-Containing Protein 452

External Ids:    HGNC: 190181   Entrez Gene: 802632   Ensembl: ENSG000001342537   OMIM: 6093185   UniProtKB: Q9H8W53   

Export aliases for TRIM45 gene to outside databases

Previous GC identifers: GC01M116493 GC01M116801 GC01M117001 GC01M117365 GC01M115511


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TRIM45 Gene:
This gene encodes a member of the tripartite motif family. The encoded protein may function as a transcriptional
repressor of the mitogen-activated protein kinase pathway. Alternatively spliced transcript variants have been
described.(provided by RefSeq, Mar 2009)

GeneCards Summary for TRIM45 Gene: 
TRIM45 (tripartite motif containing 45) is a protein-coding gene. GO annotations related to this gene include zinc ion binding. An important paralog of this gene is TRIM3.

UniProtKB/Swiss-Prot: TRI45_HUMAN, Q9H8W5
Function: May act as a transcriptional repressor in mitogen-activated protein kinase signaling pathway

Gene Wiki entry for TRIM45 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000001.10  NT_032977.9  NC_018912.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TRIM45 gene promoter:
         HOXA9   HOXA9B   AP-1   SRF (504 AA)   ATF-2   Meis-1b   HNF-4alpha1   Sox9   c-Jun   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTRIM45 promoter sequence
   Search SABiosciences Chromatin IP Primers for TRIM45

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRIM45


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p13.1   Ensembl cytogenetic band:  1p13.1   HGNC cytogenetic band: 1p13.1

TRIM45 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TRIM45 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M117654:  view genomic region     (about GC identifiers)

Start:
117,653,677 bp from pter      End:
117,665,209 bp from pter
Size:
11,533 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TRI45_HUMAN, Q9H8W5 (See protein sequence)
Recommended Name: Tripartite motif-containing protein 45  
Size: 580 amino acids; 64359 Da
Subcellular location: Cytoplasm. Nucleus
Developmental stage: Expressed in brain, lung, skeletal muscle, heart and intestine in 80-day old embryo
1 PDB 3D structure from and Proteopedia for TRIM45:
2DS4 (3D)    
Secondary accessions: Q53GN0 Q5T2K4 Q5T2K5 Q8IYV6
Alternative splicing: 2 isoforms:  Q9H8W5-1   Q9H8W5-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TRIM45: NX_Q9H8W5

Explore proteomics data for TRIM45 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9H8W5

  • TRIM45 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TRIM45 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001139107.1  NP_079464.2  

    ENSEMBL proteins: 
     ENSP00000431261   ENSP00000256649   ENSP00000358476   ENSP00000358473   ENSP00000474935  

    Human Recombinant Protein Products for TRIM45: 
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    Novus Biologicals TRIM45 Protein
    Novus Biologicals TRIM45 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TRIM45 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IEA--

    TRIM45 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    TRIM: Tripartite motif containing / Tripartite motif containing
    RNF: RING-type (C3HC4) zinc fingers

    5/9 InterPro protein domains (see all 9):
     IPR017907 Znf_RING_CS
     IPR001298 Filamin
     IPR001841 Znf_RING
     IPR014756 Ig_E-set
     IPR017868 Filamin/ABP280_repeat-like

    Graphical View of Domain Structure for InterPro Entry Q9H8W5

    ProtoNet protein and cluster: Q9H8W5

    2 Blocks protein domains:
    IPB000315 B-box zinc finger signature
    IPB001841 Zn-finger


    UniProtKB/Swiss-Prot: TRI45_HUMAN, Q9H8W5
    Similarity: Belongs to the TRIM/RBCC family
    Similarity: Contains 2 B box-type zinc fingers
    Similarity: Contains 1 filamin repeat
    Similarity: Contains 1 RING-type zinc finger


    TRIM45 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TRI45_HUMAN, Q9H8W5
    Function: May act as a transcriptional repressor in mitogen-activated protein kinase signaling pathway

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--
         
    TRIM45 for ontologies           About GeneDecksing


    Phenotypes:
         5 MGI mutant phenotypes (inferred from 1 allele(MGI details for Trim45):
     homeostasis/metabolism  mortality/aging  nervous system  skeleton  vision/eye 

    TRIM45 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for TRIM45 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TRIM45

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TRIM45 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TRIM45 

    miRNA
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    5 QIAGEN miScript miRNA Assays for microRNAs that regulate TRIM45:
    hsa-miR-124 hsa-miR-539 hsa-miR-506 hsa-miR-138-2* hsa-miR-1305
    SwitchGear 3'UTR luciferase reporter plasmidTRIM45 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
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    Gene Editing
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIM45


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TRIM45

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    5/10 Interacting proteins for TRIM45 (Q9H8W53 ENSP000002566494) via UniProtKB, MINT, STRING, and/or I2D (see all 10)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCENSP000003448184STRING: ENSP00000344818
    UBE2D1ENSP000003630194STRING: ENSP00000363019
    UBE2D2ENSP000003817174STRING: ENSP00000381717
    UBE2D3ENSP000003497224STRING: ENSP00000349722
    UBE2D4ENSP000002224024STRING: ENSP00000222402
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0060348bone development IEA--

    TRIM45 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TRIM45 (TRI45)

    Search CenterWatch for drugs/clinical trials and news about TRIM45 / TRI45

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TRIM45 gene (2 alternative transcripts): 
    NM_001145635.1  NM_025188.3  

    Unigene Cluster for TRIM45:

    Tripartite motif containing 45
    Hs.301526  [show with all ESTs]
    Unigene Representative Sequence: AY669488
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000497970 ENST00000256649(uc001egz.2) ENST00000369464(uc009whe.2)
    ENST00000369461 ENST00000485032
    miRNA
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    5 QIAGEN miScript miRNA Assays for microRNAs that regulate TRIM45:
    hsa-miR-124 hsa-miR-539 hsa-miR-506 hsa-miR-138-2* hsa-miR-1305
    SwitchGear 3'UTR luciferase reporter plasmidTRIM45 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TRIM45
    Clone
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    OriGene clones in human, mouse for TRIM45 (see all 13)
    OriGene ORF clones in mouse, rat for TRIM45
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): TRIM45 (NM_025188)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TRIM45
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRIM45
    Sirion Biotech Customized lentivirus for stable overexpression of TRIM45 
                         Customized lentivirus expression plasmids for stable overexpression of TRIM45 
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for TRIM45
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRIM45
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRIM45

    Additional mRNA sequence: 

    AK023243.1 AK222901.1 AY669488.1 BC034943.2 

    2 DOTS entries:

    DT.406608  DT.100835091 

    24/39 AceView cDNA sequences (see all 39):

    CR602755 CR595070 AI874259 AY669488 AI253072 NM_025188 BE730280 AV745626 
    BC034943 BX452649 BQ881123 AK023243 BU618486 BX383988 BX444521 BG722669 
    AI972066 AI199235 AU132216 BX383989 BX103245 AA057266 AU120085 BU846471 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for TRIM45    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c · 4d ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c
    SP1:                                            -                                       
    SP2:                                                                                    
    SP3:        -     -     -     -     -     -     -                                       
    SP4:              -                                                                     
    SP5:              -                                                                     


    ECgene alternative splicing isoforms for TRIM45

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TRIM45 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    TRIM45 Expression
    About this image


    See TRIM45 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TRIM45

    SOURCE GeneReport for Unigene cluster: Hs.301526

    UniProtKB/Swiss-Prot: TRI45_HUMAN, Q9H8W5
    Tissue specificity: Expressed in skeletal muscle, brain, heart and pancreas

        SABiosciences Expression via Pathway-Focused PCR Array including TRIM45: 
              Ubiquitin Ligases in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIM45

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for TRIM45 gene from 5/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Trim451 , 5 tripartite motif-containing 451, 5 84.6(n)1
    86.03(a)1
      3 (43.85 cM)5
    2296441  NM_194343.21  NP_919324.21 
     1009222025 
    chicken
    (Gallus gallus)
    Aves TRIM451 tripartite motif containing 45 69.78(n)
    63.55(a)
      769776  XM_001233078.2  XP_001233079.2 
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.149782 Xenopus laevis transcribed sequence with weak similarity more 80.02(n)    BJ046674.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5581171 tripartite motif-containing protein 45-like 57.01(n)
    51.18(a)
      558117  XM_681301.4  XP_686393.2 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG84191 CG8419 45.07(n)
    34.27(a)
      34118  NM_135349.2  NP_609193.1 


    ENSEMBL Gene Tree for TRIM45 (if available)
    TreeFam Gene Tree for TRIM45 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TRIM45 gene
    TRIM32  TRIM712  TRIM562  TRIM22  

    TRIM45 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/319 SNPs in TRIM45 are shown (see all 319)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1810988391,2
    --115511297(+) AAAAAA/GAAAAA 2 -- ds50010--------
    rs38417071,2
    C--115512775(-) TGTTA-/GTTA  
            
    TTCAC
    2 -- ut310--------
    rs1458492841,2
    --115524408(+) CACCTA/GGCTAA 2 -- us2k10--------
    rs616285311,2
    C--117653312(+) AAAAA-/A/GGAACC 2 -- ds50010--------
    rs113559001,2
    C--117665664(+) ATATG-/A/A   
       A
    /AAA
    AAAAA
    4 -- us2k1 cds1 trp30--------
    rs1901237961,2
    --117721881(+) TCTCAC/GCTTAC 2 -- ds50010--------
    rs109232061,2
    C,F,A--117721988(+) GCAAGA/GCTCTG 2 -- ds50015Minor allele frequency- G:0.37NA WA 128
    rs109232071,2
    C,F,A,H--117722084(+) CAGAAG/AGAGTG 2 -- ds500125Minor allele frequency- A:0.19NS EA NA WA 2772
    rs1450025681,2
    --117722172(+) AAAGAC/GGCTGA 2 -- ds50010--------
    rs13255101,2
    C,F,H--117722207(+) AGAACA/GCAGAG 2 -- ds500199Minor allele frequency- T:0.00NS NA EA PA EU CA WA 6110

    HapMap Linkage Disequilibrium report for TRIM45 (117653677 - 117665209 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for TRIM45: --
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing TRIM45
    DNA2.0 Custom Variant and Variant Library Synthesis for TRIM45

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TRIM45 for disorders           About MalaCards
    OMIM gene information: 609318    OMIM disorders: --


    TRIM45 for disorders           About GeneDecksing


    Export disorders for TRIM45 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TRIM45 gene, integrated from 9 sources (see all 12):
    (articles sorted by number of sources associating them with TRIM45)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. TRIM45, a novel human RBCC/TRIM protein, inhibits transcriptional activities of ElK-1 and AP-1. (PubMed id 15351693)1, 2, 3 Wang Y.... Liu M. (2004)
    2. Tryptic digestion of ubiquitin standards reveals an improved strategy for identifying ubiquitinated proteins by mass spectrometry. (PubMed id 17370265)1, 2 Denis N.J.... Figeys D. (2007)
    3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. TRIM45 negatively regulates NF-kB-mediated transcripti on and suppresses cell proliferation. (PubMed id 22634006)1 Shibata M....Hatakeyama S. (2012)
    7. Functional interactions between ubiquitin E2 enzymes a nd TRIM proteins. (PubMed id 21143188)1 Napolitano L.M....Meroni G. (2011)
    8. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
    9. Genomic analysis of the TRIM family reveals two groups of genes with distinct evolutionary properties. (PubMed id 18673550)1 Sardiello M....Meroni G. (2008)
    10. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 80263 HGNC: 19018 AceView: TRIM45 Ensembl:ENSG00000134253 euGenes: HUgn80263
    ECgene: TRIM45 H-InvDB: TRIM45

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TRIM45 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TRIM45 gene:
    Search GeneIP for patents involving TRIM45

    GeneCards and IP:
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