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Aliases for TRIM44 Gene

Aliases for TRIM44 Gene

  • Tripartite Motif Containing 44 2 3
  • Tripartite Motif-Containing 44 2 3
  • DIPB 3 4
  • Tripartite Motif-Containing Protein 44 3
  • Protein DIPB 4
  • HSA249128 3
  • MC7 3

External Ids for TRIM44 Gene

Previous GeneCards Identifiers for TRIM44 Gene

  • GC11P036362
  • GC11P035723
  • GC11P035648
  • GC11P035640
  • GC11P035382

Summaries for TRIM44 Gene

Entrez Gene Summary for TRIM44 Gene

  • This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, namely a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. [provided by RefSeq, Jul 2008]

GeneCards Summary for TRIM44 Gene

TRIM44 (Tripartite Motif Containing 44) is a Protein Coding gene.

UniProtKB/Swiss-Prot for TRIM44 Gene

  • May play a role in the process of differentiation and maturation of neuronal cells (By similarity). May regulate the activity of TRIM17.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRIM44 Gene

Genomics for TRIM44 Gene

Regulatory Elements for TRIM44 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for TRIM44 Gene

Start:
35,662,692 bp from pter
End:
35,818,007 bp from pter
Size:
155,316 bases
Orientation:
Plus strand

Genomic View for TRIM44 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TRIM44 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRIM44 Gene

Proteins for TRIM44 Gene

  • Protein details for TRIM44 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96DX7-TRI44_HUMAN
    Recommended name:
    Tripartite motif-containing protein 44
    Protein Accession:
    Q96DX7
    Secondary Accessions:
    • D3DR14
    • Q96QY2
    • Q9UGK0

    Protein attributes for TRIM44 Gene

    Size:
    344 amino acids
    Molecular mass:
    38472 Da
    Quaternary structure:
    • Interacts (via coiled coil) with TRIM17 (via coiled coil).

neXtProt entry for TRIM44 Gene

Proteomics data for TRIM44 Gene at MOPED

Post-translational modifications for TRIM44 Gene

  • Ubiquitination at Lys225, Lys231, Lys256, Lys268, and Lys314
  • Modification sites at PhosphoSitePlus

Other Protein References for TRIM44 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TRIM44 Gene

Domains for TRIM44 Gene

Gene Families for TRIM44 Gene

HGNC:
  • RNF :RING-type (C3HC4) zinc fingers
  • TRIM :Tripartite motif containing / Tripartite motif containing

Protein Domains for TRIM44 Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for TRIM44 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96DX7

UniProtKB/Swiss-Prot:

TRI44_HUMAN :
  • Q96DX7
Similarity:
  • Contains 1 B box-type zinc finger.
genes like me logo Genes that share domains with TRIM44: view

Function for TRIM44 Gene

Molecular function for TRIM44 Gene

UniProtKB/Swiss-Prot Function: May play a role in the process of differentiation and maturation of neuronal cells (By similarity). May regulate the activity of TRIM17.

Gene Ontology (GO) - Molecular Function for TRIM44 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 17577209
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with TRIM44: view
genes like me logo Genes that share phenotypes with TRIM44: view

Animal Model Products

CRISPR Products

miRNA for TRIM44 Gene

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TRIM44

In Situ Assay Products

Flow Cytometry Products

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for TRIM44 Gene

Localization for TRIM44 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TRIM44 Gene COMPARTMENTS Subcellular localization image for TRIM44 gene
Compartment Confidence
nucleus 3
cytosol 2
cytoskeleton 1
extracellular 1
lysosome 1

Gene Ontology (GO) - Cellular Components for TRIM44 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
genes like me logo Genes that share ontologies with TRIM44: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for TRIM44 Gene

Pathways for TRIM44 Gene

SuperPathways for TRIM44 Gene

No Data Available

PCR Array Products

  • Pathway & Disease-focused RT² Profiler PCR Arrays

Gene Ontology (GO) - Biological Process for TRIM44 Gene

None

No data available for Pathways by source for TRIM44 Gene

Transcripts for TRIM44 Gene

mRNA/cDNA for TRIM44 Gene

Unigene Clusters for TRIM44 Gene

Tripartite motif containing 44:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TRIM44

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRIM44 Gene

No ASD Table

Relevant External Links for TRIM44 Gene

GeneLoc Exon Structure for
TRIM44
ECgene alternative splicing isoforms for
TRIM44

Expression for TRIM44 Gene

mRNA expression in normal human tissues for TRIM44 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for TRIM44 Gene

SOURCE GeneReport for Unigene cluster for TRIM44 Gene Hs.192103

mRNA Expression by UniProt/SwissProt for TRIM44 Gene

Q96DX7-TRI44_HUMAN
Tissue specificity: Highly expressed in testis.
genes like me logo Genes that share expressions with TRIM44: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for TRIM44 Gene

Orthologs for TRIM44 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TRIM44 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia TRIM44 35
  • 99.52 (n)
  • 100 (a)
TRIM44 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia TRIM44 35
  • 89.22 (n)
  • 89.02 (a)
TRIM44 36
  • 90 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TRIM44 35
  • 82.78 (n)
  • 82.98 (a)
TRIM44 36
  • 84 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Trim44 35
  • 86.39 (n)
  • 88.76 (a)
Trim44 16
Trim44 36
  • 92 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TRIM44 36
  • 50 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia TRIM44 36
  • 51 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Trim44 35
  • 81.78 (n)
  • 82.27 (a)
lizard
(Anolis carolinensis)
Reptilia TRIM44 36
  • 43 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia trim44 35
  • 59.51 (n)
  • 46.58 (a)
zebrafish
(Danio rerio)
Actinopterygii trim44 35
  • 53.7 (n)
  • 40.91 (a)
trim44 36
  • 31 (a)
OneToOne
Species with no ortholog for TRIM44:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TRIM44 Gene

ENSEMBL:
Gene Tree for TRIM44 (if available)
TreeFam:
Gene Tree for TRIM44 (if available)

Paralogs for TRIM44 Gene

No data available for Paralogs for TRIM44 Gene

Variants for TRIM44 Gene

Sequence variations from dbSNP and Humsavar for TRIM44 Gene

SNP ID Clin Chr 11 pos Sequence Context AA Info Type MAF
rs6709 -- 35,807,928(-) GATTT(C/T)CCCCA utr-variant-3-prime
rs12809 -- 35,807,757(-) AATAA(A/G)AATTA utr-variant-3-prime
rs504423 -- 35,684,686(+) TATGG(G/T)TTTTT intron-variant
rs511160 -- 35,664,420(+) cactt(C/T)ggaaa intron-variant
rs531239 -- 35,681,743(+) TTCTG(C/T)TCCAC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for TRIM44 Gene

Variant ID Type Subtype PubMed ID
nsv832121 CNV Gain 17160897

Relevant External Links for TRIM44 Gene

HapMap Linkage Disequilibrium report
TRIM44

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TRIM44 Gene

Disorders for TRIM44 Gene

(1) University of Copenhagen DISEASES for TRIM44 Gene

Relevant External Links for TRIM44

Genetic Association Database (GAD)
TRIM44
Human Genome Epidemiology (HuGE) Navigator
TRIM44
genes like me logo Genes that share disorders with TRIM44: view

No data available for UniProtKB/Swiss-Prot for TRIM44 Gene

Publications for TRIM44 Gene

  1. Human chromosome 11 DNA sequence and analysis including novel gene identification. (PMID: 16554811) Taylor T.D. … Sakaki Y. (Nature 2006) 3 4
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. TRIM44 interacts with and stabilizes terf, a TRIM ubiquitin E3 ligase. (PMID: 19358823) Urano T. … Inoue S. (Biochem. Biophys. Res. Commun. 2009) 3 4
  5. Genomewide association study of movement-related adverse antipsychotic effects. (PMID: 19875103) Aberg K. … van den Oord E.J. (Biol. Psychiatry 2010) 3 48

Products for TRIM44 Gene

Sources for TRIM44 Gene

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