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Aliases for TRIM43B Gene

Aliases for TRIM43B Gene

  • Tripartite Motif Containing 43B 2 3
  • Tripartite Motif-Containing 43B 2

External Ids for TRIM43B Gene

Previous GeneCards Identifiers for TRIM43B Gene

  • GC02M095508
  • GC02M096143
  • GC02M090143

Summaries for TRIM43B Gene

Entrez Gene Summary for TRIM43B Gene

  • This gene encodes a member of a family of proteins containing RING-finger, SPRY, and BBC domains. There is no definitive support for transcription of this locus, and the transcript structure is inferred from other family members. [provided by RefSeq, Oct 2009]

GeneCards Summary for TRIM43B Gene

TRIM43B (Tripartite Motif Containing 43B) is a Protein Coding gene. An important paralog of this gene is TRIM43.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRIM43B Gene

Genomics for TRIM43B Gene

Genomic Location for TRIM43B Gene

95,476,967 bp from pter
95,484,731 bp from pter
7,765 bases
Minus strand

Genomic View for TRIM43B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TRIM43B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRIM43B Gene

No data available for Regulatory Elements for TRIM43B Gene

Proteins for TRIM43B Gene

  • Protein details for TRIM43B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Tripartite motif-containing protein 43B
    Protein Accession:
    Secondary Accessions:

    Protein attributes for TRIM43B Gene

    446 amino acids
    Molecular mass:
    52310 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRIM43B Gene

Proteomics data for TRIM43B Gene at MOPED

Post-translational modifications for TRIM43B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TRIM43B Gene

REFSEQ proteins:

No data available for DME Specific Peptides for TRIM43B Gene

Domains for TRIM43B Gene

Gene Families for TRIM43B Gene

  • RNF :RING-type (C3HC4) zinc fingers
  • TRIM :Tripartite motif containing / Tripartite motif containing

Protein Domains for TRIM43B Gene

Suggested Antigen Peptide Sequences for TRIM43B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • A6NCK2
  • Contains 1 B30.2/SPRY domain.
  • Belongs to the TRIM/RBCC family.
  • Contains 1 B box-type zinc finger.
  • Contains 1 RING-type zinc finger.
genes like me logo Genes that share domains with TRIM43B: view

Function for TRIM43B Gene

Gene Ontology (GO) - Molecular Function for TRIM43B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008270 zinc ion binding IEA --
genes like me logo Genes that share ontologies with TRIM43B: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TRIM43B

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TRIM43B Gene

Localization for TRIM43B Gene

Subcellular locations from

Jensen Localization Image for TRIM43B Gene COMPARTMENTS Subcellular localization image for TRIM43B gene
Compartment Confidence
nucleus 3
cytosol 2

Gene Ontology (GO) - Cellular Components for TRIM43B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005622 intracellular IEA --
genes like me logo Genes that share ontologies with TRIM43B: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for TRIM43B Gene

Pathways for TRIM43B Gene

SuperPathways for TRIM43B Gene

No Data Available

Interacting Proteins for TRIM43B Gene

Gene Ontology (GO) - Biological Process for TRIM43B Gene


No data available for Pathways by source for TRIM43B Gene

Transcripts for TRIM43B Gene

mRNA/cDNA for TRIM43B Gene

(2) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for TRIM43B

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRIM43B Gene

No ASD Table

Relevant External Links for TRIM43B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TRIM43B Gene

mRNA expression in normal human tissues for TRIM43B Gene

mRNA differential expression in normal tissues according to GTEx for TRIM43B Gene

This gene is overexpressed in Testis (19.3), Brain - Cerebellum (10.7), and Brain - Cerebellar Hemisphere (7.5).

SOURCE GeneReport for Unigene cluster for TRIM43B Gene Hs.723811

genes like me logo Genes that share expressions with TRIM43B: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for TRIM43B Gene

Orthologs for TRIM43B Gene

This gene was present in the common ancestor of mammals.

Orthologs for TRIM43B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia LOC528629 35
  • 69.41 (n)
  • 51.6 (a)
(Pan troglodytes)
Mammalia LOC739911 35
  • 98.8 (n)
  • 97.31 (a)
(Rattus norvegicus)
Mammalia Trim43a 35
  • 64.86 (n)
  • 47.51 (a)
Species with no ortholog for TRIM43B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TRIM43B Gene

Gene Tree for TRIM43B (if available)
Gene Tree for TRIM43B (if available)

Paralogs for TRIM43B Gene

Paralogs for TRIM43B Gene

genes like me logo Genes that share paralogs with TRIM43B: view

Variants for TRIM43B Gene

Sequence variations from dbSNP and Humsavar for TRIM43B Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type MAF
rs2059312 -- 95,485,856(-) ACATT(C/T)GCATG upstream-variant-2KB
rs2551287 -- 95,484,488(+) AACTC(A/G)GAAAA intron-variant, upstream-variant-2KB
rs2707328 -- 95,485,640(+) CAACT(G/T)CATCT upstream-variant-2KB
rs2707329 -- 95,485,826(+) GGAAG(A/C)CTTTG upstream-variant-2KB
rs2911531 -- 95,485,193(-) TTACT(A/G)TATTT upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for TRIM43B Gene

Variant ID Type Subtype PubMed ID
dgv1228e1 CNV Complex 17122850
nsv7320 OTHER Inversion 18451855
nsv834300 CNV Gain 17160897
nsv874660 CNV Gain 21882294
nsv222 OTHER Inversion 15895083

Relevant External Links for TRIM43B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for TRIM43B Gene

Disorders for TRIM43B Gene

No disorders were found for TRIM43B Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for TRIM43B Gene

Publications for TRIM43B Gene

  1. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PMID: 15815621) Hillier L.W. … Wilson R.K. (Nature 2005) 3 4

Products for TRIM43B Gene

Sources for TRIM43B Gene

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