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TRIM41 Gene

protein-coding GIFtS: 50
GCID: GC05P180649

Tripartite Motif Containing 41

(Previous name: tripartite motif-containing 41)

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(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
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Aliases
Tripartite Motif Containing 41¹ ²		Tripartite Motif-Containing 41¹
RING-Finger Protein That Interacts With C Kinase¹ ²		E3 Ubiquitin-Protein Ligase TRIM41²
RINCK² ³		EC 6.3.2.-³
RING Finger-Interacting Protein With C Kinase² ³		Tripartite Motif-Containing Protein 41³

External Ids:	HGNC: 19013¹	Entrez Gene: 90933²	Ensembl: ENSG00000146063⁷	OMIM: 610530⁵	UniProtKB: Q8WV44³

Export aliases for TRIM41 gene to outside databases

Previous GC identifers: GC05M181702 GC05P180712 GC05P180759 GC05P180582 GC05P175377

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for TRIM41 Gene:

This gene encodes a member of the tripartite motif (TRIM) family. The TRIM family is characterized by a signature

motif composed of a RING finger, one or more B-box domains, and a coiled-coil region. This encoded protein may

play a role in protein kinase C signaling. Multiple transcript variants encoding different isoforms have been

found for this gene. (provided by RefSeq, Oct 2011)

GeneCards Summary for TRIM41 Gene:

TRIM41 (tripartite motif containing 41) is a protein-coding gene. GO annotations related to this gene include ligase activity. An important paralog of this gene is TRIM31.

UniProtKB/Swiss-Prot: TRI41_HUMAN, Q8WV44

Function: Functions as an E3 ligase that catalyzes the ubiquitin-mediated degradation of protein kinase C

Gene Wiki entry for TRIM41 Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:

NC_000005.9 NT_023133.14 NC_018916.2

Regulatory elements:

Regulatory transcription factor binding sites in the TRIM41 gene promoter:
HEN1 AREB6 FAC1 Tal-1 Sp1 MyoD E47
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): TRIM41 promoter sequence

Search Chromatin IP Primers for TRIM41

Epigenetics:

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TRIM41

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q35.3 Ensembl cytogenetic band: 5q35.3 HGNC cytogenetic band: 5q35.3

TRIM41 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TRIM41 gene location

GeneLoc information about chromosome 5 GeneLoc Exon Structure

GeneLoc location for GC05P180649: view genomic region (about GC identifiers)

Start:	180,649,499 bp from pter	End:	180,662,809 bp from pter
Size:	13,311 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: TRI41_HUMAN, Q8WV44 (See protein sequence)

Recommended Name: E3 ubiquitin-protein ligase TRIM41

Size: 630 amino acids; 71670 Da

Subunit: Interacts with PRKCA

1 PDB 3D structure from and Proteopedia for TRIM41:

2EGM (3D)

Secondary accessions: B3KNJ6 D3DWR9 Q5BKT0 Q7L484 Q96Q10 Q9BSL8

Alternative splicing: 4 isoforms: Q8WV44-1 Q8WV44-2 Q8WV44-3 Q8WV44-4

Explore the universe of human proteins at neXtProt for TRIM41: NX_Q8WV44

Explore proteomics data for TRIM41 at MOPED

Post-translational modifications:

Auto-ubiquitinated¹

Ubiquitination² at Lys307, Lys512, Lys557, Lys575

Modification sites at PhosphoSitePlus

See TRIM41 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (2 alternative transcripts):

NP_291027.3 NP_963921.1

ENSEMBL proteins:

ENSP00000426803 ENSP00000336749 ENSP00000320869 ENSP00000424979 ENSP00000426790

TRIM41 Human Recombinant Protein Products:

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	Novus Biologicals TRIM41 Lysate
	Browse Sino Biological Recombinant Proteins Browse Sino Biological Cell Lysates
	Browse ProSpec Recombinant Proteins
	Cloud-Clone Corp. Proteins for TRIM41
	Search eBioscience for Proteins for TRIM41
	antibodies-online proteins for TRIM41 (3 products)
	antibodies-online peptides for TRIM41

TRIM41 Antibody Products:

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	antibodies-online antibodies for TRIM41 (35 products)

TRIM41 Assay Products:

	Browse Kits and Assays available from EMD Millipore
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	Browse Enzo Life Sciences for kits & assays
	Cloud-Clone Corp. ELISAs for TRIM41 Cloud-Clone Corp. CLIAs for TRIM41
	Search eBioscience for ELISAs for TRIM41
	antibodies-online kits for TRIM41 (4 products)

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:

TRIM: Tripartite motif containing / Tripartite motif containing

RNF: RING-type (C3HC4) zinc fingers

Selected InterPro protein domains (see all 9):

IPR006574 PRY

IPR017907 Znf_RING_CS

IPR001841 Znf_RING

IPR001870 B30.2/SPRY

IPR003877 SPRY_rcpt

Graphical View of Domain Structure for InterPro Entry Q8WV44

ProtoNet protein and cluster: Q8WV44

4 Blocks protein domains:

IPB000315 B-box zinc finger signature

IPB001841 Zn-finger

IPB003879 Butyrophylin C-terminal DUF signature

IPB006574 SPRY-associated domain

UniProtKB/Swiss-Prot: TRI41_HUMAN, Q8WV44

Similarity: Belongs to the TRIM/RBCC family

Similarity: Contains 1 B box-type zinc finger

Similarity: Contains 1 B30.2/SPRY domain

Similarity: Contains 1 RING-type zinc finger

Find genes that share domains with TRIM41 About GenesLikeMe

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

UniProtKB/Swiss-Prot Summary: TRI41_HUMAN, Q8WV44

Function: Functions as an E3 ligase that catalyzes the ubiquitin-mediated degradation of protein kinase C

Enzyme Number (IUBMB): EC 6.3.2.-¹

Gene Ontology (GO): 4 molecular function terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IPI	17893151
GO:0008270	zinc ion binding	IEA	--
GO:0016874	ligase activity	IEA	--
GO:0046872	metal ion binding	--	--

Find genes that share ontologies with TRIM41 About GenesLikeMe

Phenotypes:
2 GenomeRNAi human phenotypes for TRIM41:

Cell cycle / mitosis defect

Decreased TP53 protein express

Animal Models:

genOway: Develop your customized and physiologically relevant rodent model for TRIM41

miRNA Products:		Block miRNA regulation of human, mouse, rat TRIM41 using miScript Target Protectors
		Selected qRT-PCR Assays for microRNAs that regulate TRIM41 (see all 32):
		hsa-miR-596 hsa-let-7d hsa-miR-766 hsa-miR-449a hsa-miR-4267 hsa-let-7g hsa-let-7a hsa-miR-330-3p

		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for TRIM41
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Gene Editing
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		GenScript: all cDNA clones in your preferred vector (see all 2): TRIM41 (NM_033549)
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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIM41

(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot

TRI41_HUMAN, Q8WV44: Cytoplasm. Nucleus

Subcellular locations from COMPARTMENTS:

Compartment	Confidence
nucleus	5
cytosol	2

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Gene Ontology (GO): 4 cellular component terms: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005622	intracellular	--	--
GO:0005634	nucleus	--	--
GO:0005730	nucleolus	IDA	--
GO:0005737	cytoplasm	IEA	--

Find genes that share ontologies with TRIM41 About GenesLikeMe

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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UniProtKB/Swiss-Prot: TRI41_HUMAN, Q8WV44

Pathway: Protein modification; protein ubiquitination

Pathway & Disease-focused RT² Profiler PCR Array including TRIM41:

Ubiquitin Ligases in human mouse rat

Interactions:

Search GeneGlobe Interaction Network for TRIM41

STRING Interaction Network Preview (showing 5 interactants - click image to see 21)

Selected Interacting proteins for TRIM41 (Q8WV44^{1, 2, 3} ENSP00000320869⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 28)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
LINC00921	O14978²^,³	MINT-67444 I2D: score=5
ZBTB8A	Q96BR9²^,³, ENSP00000362609⁴	MINT-66365 I2D: score=3 STRING: ENSP00000362609
MPP3	Q13368²^,³	MINT-64793 I2D: score=4
ZNF263	O14978²^,³, ENSP00000219069⁴	MINT-67444 I2D: score=5 STRING: ENSP00000219069
ZNF473	Q8WTR7²^,³, ENSP00000270617⁴	MINT-68105 I2D: score=5 STRING: ENSP00000270617

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Gene Ontology (GO): 1 biological process term: About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0016567	protein ubiquitination	IEA	--

Find genes that share ontologies with TRIM41 About GenesLikeMe

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse compounds at ApexBio

Browse Tocris compounds for TRIM41 (TRI41)

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for TRIM41 gene (2 alternative transcripts):

NM_033549.4 NM_201627.2

Unigene Cluster for TRIM41:

Tripartite motif containing 41

Hs.441488 [show with all ESTs]

Unigene Representative Sequence: AK074052

9 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000515499 ENST00000508930(uc003mng.1) ENST00000351937(uc003mnd.2 uc003mnf.2)

ENST00000315073(uc003mne.2) ENST00000503114 ENST00000515223(uc003mnc.2)

ENST00000515834(uc010jlq.1) ENST00000514219 ENST00000510072

miRNA Products:		Block miRNA regulation of human, mouse, rat TRIM41 using miScript Target Protectors
		Selected qRT-PCR Assays for microRNAs that regulate TRIM41 (see all 32):
		hsa-miR-596 hsa-let-7d hsa-miR-766 hsa-miR-449a hsa-miR-4267 hsa-let-7g hsa-let-7a hsa-miR-330-3p

		Browse SwitchGear 3'UTR luciferase reporter plasmids

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		Predesigned siRNA for gene silencing in human, mouse, rat TRIM41

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		GenScript: all cDNA clones in your preferred vector (see all 2): TRIM41 (NM_033549)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for TRIM41
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRIM41

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for TRIM41
		Pre-validated RT² qPCR Primer Assay in human, mouse / rat TRIM41
		QuantiTect SYBR Green Assays in human, mouse, rat TRIM41
		QuantiFast Probe-based Assays in human, mouse, rat TRIM41

Additional mRNA sequence:

AB063180.1 AB100366.1 AB100367.1 AK027601.1 AK074052.1 AK307695.1 AL832960.1 BC004956.1

BC009762.2 BC018765.1 BC071887.1 BC090953.1 BC111568.1 BC127194.1 CR457349.1 NR_045218.1

9 DOTS entries:

DT.95168968 DT.100788355 DT.100788354 DT.100788352 DT.100788353 DT.120838296 DT.100788350 DT.100718926

DT.85104364

Selected AceView cDNA sequences (see all 177):

AL832960 BQ011723 BM563451 Z39599 AL046617 CA430637 BQ012651 BM703995

AL137593 BU070299 AI884960 BU070531 CD366889 AX775803 BC004956 AX775789

AX775795 BQ130118 AK074052 AB063180 BU616379 BI793213 BU622606 NM_201627

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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TRIM41 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: TTCTTTGGGA

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TRIM41 Protein expression data from MOPED¹, PaxDb² and MaxQB³:

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TRIM41 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.441488

UniProtKB/Swiss-Prot: TRI41_HUMAN, Q8WV44

Tissue specificity: Expressed in multiple tissues with the highest levels in heart and skeletal muscle

Pathway & Disease-focused RT² Profiler PCR Array including TRIM41:

Ubiquitin Ligases in human mouse rat

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		Pre-validated RT² qPCR Primer Assay in human, mouse / rat TRIM41
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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIM41

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of chordates.

Orthologs for TRIM41 gene from Selected species (see all 10) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Trim41^{1 , 5}	tripartite motif-containing 41^{1, 5}	87.39(n)¹ 91.41(a)¹		11 (28.78 cM)⁵ 211007¹ NM_145377.2¹ NP_663352.2¹ 48806404⁵
chicken (Gallus gallus)	Aves	TRIM41¹	tripartite motif containing 41	64.21(n) 61.28(a)		417043 NM_001030672.2 NP_001025843.1
lizard (Anolis carolinensis)	Reptilia	--	--	54(a)	1 → many	2(188794430-188807675)
zebrafish (Danio rerio)	Actinopterygii	trim105⁶	tripartite motif containing 105	25(a)	many ↔ many	14(19874099-19890345) ENSDARG00000057550

ENSEMBL Gene Tree for TRIM41 (if available)
TreeFam Gene Tree for TRIM41 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
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Paralogs for TRIM41 gene

TRIM31² TRIM50² TRIM10² TRIM73² TRIM69² TRIM15² TRIM26² TRIM74²

TRIM35² TRIM52² TRIM62² TRIM72²

Selected SIMAP similar genes for TRIM41 using alignment to 5 protein entries: TRI41_HUMAN (see all proteins) (see all similar genes):

FLJ00123 DKFZp666N1710 DKFZp434N1710 TRIM52 TRIM64 TRIM64B

ERMAP TRIM35 TRIM31 TRIM2 TRIM17 TRIM39

TRIM51 TRIM64C TRIM49 TRIM49C TRIM60 TRIM21

Find genes that share paralogs with TRIM41 About GenesLikeMe

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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SNP ID	Valid	Clinical significance	Chr 5 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs11347848^1,2	C,F	--	175380986(+)	`CCCCCT/-TTTTT`	3	--	int¹ trp³		2		NA	4
rs11741493^1,2	C,F,H	--	175382894(+)	`aaaaaC/Aaaaaa`	3	--	int¹ trp³		1		NA	2
rs112133006^1,2	C	--	180655844(+)	`CAGGAA/GAATTG`	3	--	int¹		1		CSA	1
rs140820006^1,2	C	--	180865493(+)	`GCGCAC/TGGCCC`	3	--	us2k¹		0	--	--	--	--
rs187073395^1,2		--	180865577(+)	`CTCTTA/GAAGTC`	3	--	us2k¹		0	--	--	--	--
rs55909571^1,2	C,F	--	180865927(+)	`CGCGGT/CGCTGG`	3	--	us2k¹		2		NA	122
rs111565255^1,2	C,F	--	180865973(+)	`TTCTTT/CCTTTG`	3	--	us2k¹		2		NA	122
rs150147680^1,2		--	180866034(+)	`CACACA/GGATCG`	3	--	us2k¹		0	--	--	--	--
rs190428368^1,2		--	180866039(+)	`GGATCA/GGAGAA`	3	--	us2k¹		0	--	--	--	--
rs182671965^1,2		--	180866053(+)	`CAGGTG/TAGTCC`	3	--	us2k¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for TRIM41 (180649499 - 180662809 bp)

Structural Variations
Database of Genomic Variants (DGV) 7 variations for TRIM41: About this table

Variant ID	Type	Subtype	PubMed ID
nsv462591	CNV	Loss	19166990
nsv830567	CNV	Loss	17160897
nsv517697	CNV	Loss	19592680
dgv6408n71	CNV	Loss	21882294
dgv6409n71	CNV	Loss	21882294
nsv883305	CNV	Gain	21882294
nsv428133	CNV	Gain	18775914

Site Specific Mutation Identification with PCR Assays

SeqTarget long-range PCR primers for resequencing TRIM41

DNA2.0 Custom Variant and Variant Library Synthesis for TRIM41

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 610530 OMIM disorders: --

Find genes that share disorders with TRIM41 About GenesLikeMe

Export disorders for TRIM41 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for TRIM41 gene, integrated from 10 sources (see all 22):
(articles sorted by number of sources associating them with TRIM41)

Utopia: connect your pdf to the dynamic
world of online information

Intracellular localization and domain organization of human TRIM41 proteins. (PubMed id 16022281)^{1, 2, 3} Tanaka M.... Hanai R. (Mol. Biol. Rep. 2005)
Amplitude control of protein kinase C by RINCK, a novel E3 ubiquitin ligase. (PubMed id 17893151)^{1, 2} Chen D.... Newton A.C. (J. Biol. Chem. 2007)
Large-scale cDNA transfection screening for genes related to cancer development and progression. (PubMed id 15498874)^{1, 2} Wan D....Gu J. (Proc. Natl. Acad. Sci. U.S.A. 2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S.... Malek J. (Genome Res. 2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (Nat. Genet. 2004)
M phase-specific association of human topoisomerase IIIbeta with chromosomes. (PubMed id 11549288)^{1, 2} Kobayashi M. and Hanai R. (Biochem. Biophys. Res. Commun. 2001)
Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions. (PubMed id 24255178)¹ Couzens A.L....Gingras A.C. (Sci Signal 2013)
The protein interaction landscape of the human CMGC kinase group. (PubMed id 23602568)¹ Varjosalo M....Gstaiger M. (Cell Rep 2013)
Systematic analysis of dimeric E3-RING interactions reveals increased combinatorial complexity in human ubiquitination networks. (PubMed id 22493164)¹ Woodsmith J....Sanderson C.M. (amp 2012)
Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition. (PubMed id 22939624)¹ Taipale M....Lindquist S. (Cell 2012)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 90933	HGNC: 19013	AceView: TRIM41	Ensembl:ENSG00000146063	euGenes: HUgn90933
ECgene: TRIM41	H-InvDB: TRIM41

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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Name	Description
PharmGKB entry for TRIM41	Pharmacogenomics, SNPs, Pathways

Intellectual Property for TRIM41 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for TRIM41 gene:
Search GeneIP for patents involving TRIM41

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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TRIM41 Gene

Tripartite Motif Containing 41

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TRIM41 Gene

Tripartite Motif Containing 41

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