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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TRIM40 Gene

protein-coding   GIFtS: 45
GCID: GC06P030103

Tripartite Motif Containing 40

(Previous name: tripartite motif-containing 40)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Tripartite Motif Containing 401 2     RING Finger Protein 352 3
Tripartite Motif-Containing 401 2     Ring Finger Protein 402
Probable E3 NEDD8-Protein Ligase2 3     Ring Finger RNF352
RNF352 3     Tripartite Motif-Containing Protein 402

External Ids:    HGNC: 187361   Entrez Gene: 1356442   Ensembl: ENSG000002046147   UniProtKB: Q6P9F53   

Export aliases for TRIM40 gene to outside databases

Previous GC identifers: GC06P030189 GC06P029875 GC06P030210 GC06P030212 GC06P029920


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for TRIM40 Gene: 
TRIM40 (tripartite motif containing 40) is a protein-coding gene. Diseases associated with TRIM40 include multiple sclerosis, and systemic lupus erythematosus. GO annotations related to this gene include zinc ion binding.

UniProtKB/Swiss-Prot: TRI40_HUMAN, Q6P9F5
Function: May function as an E3 ubiquitin-protein ligase of the NEDD8 conjugation pathway. Promotes neddylation of
IKBKG/NEMO, stabilizing NFKBIA, and inhibiting of NF-kappaB nuclear translocation and activity




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NT_007592.15  NT_113891.2  NT_167244.1  NT_167245.1  NT_167246.1  NT_167247.1  NT_167248.1  
NT_167249.1  NC_018917.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TRIM40 gene promoter:
         Bach1   Elk-1   GCNF   IRF-1   LCR-F1   c-Ets-1   PPAR-gamma1   GCNF-1   PPAR-gamma2   GCNF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTRIM40 promoter sequence
   Search SABiosciences Chromatin IP Primers for TRIM40

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRIM40


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p22.1   Ensembl cytogenetic band:  6p22.1   HGNC cytogenetic band: 6p21.31

TRIM40 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TRIM40 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P030103:  view genomic region     (about GC identifiers)

Start:
30,103,885 bp from pter      End:
30,116,512 bp from pter
Size:
12,628 bases      Orientation:
plus strand

6/7 alternative locations (see all 7):
Chr6+,NT_167248 1,397,457-1,409,460      Chr6+,NT_167247 1,486,407-1,498,402      Chr6+,NT_167249 1,434,970-1,446,965     
Chr6+,NT_113891.2 1,616,644-1,628,649      Chr6+,NT_167245 1,398,236-1,410,237      Chr6+,NT_167244 1,344,745-1,356,747     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TRI40_HUMAN, Q6P9F5 (See protein sequence)
Recommended Name: Tripartite motif-containing protein 40  
Size: 258 amino acids; 29336 Da
Subunit: Interacts with NEDD8
Secondary accessions: Q5SRJ6 Q5SS36 Q8TD96
Alternative splicing: 2 isoforms:  Q6P9F5-1   Q6P9F5-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TRIM40: NX_Q6P9F5

Explore proteomics data for TRIM40 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q6P9F5

  • TRIM40 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TRIM40 Protein Expression
    REFSEQ proteins: NP_619645.1  
    ENSEMBL proteins: 
     ENSP00000379826   ENSP00000308310   ENSP00000365914  

    Human Recombinant Protein Products for TRIM40: 
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    OriGene Protein Over-expression Lysate for TRIM40
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for TRIM40
    GenScript Custom Purified and Recombinant Proteins Services for TRIM40
    Novus Biologicals TRIM40 Protein
    Novus Biologicals TRIM40 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TRIM40 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular IEA--

    TRIM40 for ontologies           About GeneDecksing



    TRIM40 Antibody Products: 
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    LSBio Antibodies in human, mouse, rat for TRIM40 

    Assay Products for TRIM40: 
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    Cloud-Clone Corp. ELISAs for TRIM40 
    Cloud-Clone Corp. CLIAs for TRIM40


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    TRIM: Tripartite motif containing / Tripartite motif containing
    RNF: RING-type (C3HC4) zinc fingers

    4 InterPro protein domains:
     IPR017907 Znf_RING_CS
     IPR001841 Znf_RING
     IPR000315 Znf_B-box
     IPR013083 Znf_RING/FYVE/PHD

    Graphical View of Domain Structure for InterPro Entry Q6P9F5

    ProtoNet protein and cluster: Q6P9F5

    2 Blocks protein domains:
    IPB000315 B-box zinc finger signature
    IPB001841 Zn-finger


    UniProtKB/Swiss-Prot: TRI40_HUMAN, Q6P9F5
    Similarity: Belongs to the TRIM/RBCC family
    Similarity: Contains 1 B box-type zinc finger
    Similarity: Contains 1 RING-type zinc finger


    TRIM40 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TRI40_HUMAN, Q6P9F5
    Function: May function as an E3 ubiquitin-protein ligase of the NEDD8 conjugation pathway. Promotes neddylation of
    IKBKG/NEMO, stabilizing NFKBIA, and inhibiting of NF-kappaB nuclear translocation and activity

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000166nucleotide binding ----
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--
    GO:0046872metal ion binding ----
         
    TRIM40 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for TRIM40 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TRIM40

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TRIM40 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TRIM40 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TRIM40
    1 QIAGEN miScript miRNA Assays for microRNA that regulate TRIM40:
    hsa-miR-224
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TRIM40
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TRIM40

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TRIM40
    Sirion Biotech Customized adenovirus for overexpression of TRIM40

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for TRIM40 (see all 8)
    OriGene ORF clones in mouse, rat for TRIM40
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TRIM40 (NM_138700)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TRIM40
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRIM40
    Sirion Biotech Customized lentivirus for stable overexpression of TRIM40 
                         Customized lentivirus expression plasmids for stable overexpression of TRIM40 

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for TRIM40
    Search LifeMap BioReagents cell lines for TRIM40
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIM40


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TRIM40

    4 Interacting proteins for TRIM40 (Q6P9F53) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CHUKO151113I2D: score=1 
    IKBKBO149203I2D: score=1 
    IKBKGQ9Y6K93I2D: score=1 
    NEDD8Q158433I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TRIM40 (TRI40)

    Search CenterWatch for drugs/clinical trials and news about TRIM40 / TRI40

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TRIM40 gene: 
    NM_138700.3  

    Unigene Cluster for TRIM40:

    Tripartite motif containing 40
    Hs.509439  [show with all ESTs]
    Unigene Representative Sequence: BC060785
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000396581(uc003npk.2) ENST00000489892 ENST00000307859 ENST00000376724(uc003npm.2)

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TRIM40
    1 QIAGEN miScript miRNA Assays for microRNA that regulate TRIM40:
    hsa-miR-224
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TRIM40
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TRIM40
    Clone
    Products:
         
    OriGene clones in human, mouse for TRIM40 (see all 8)
    OriGene ORF clones in mouse, rat for TRIM40
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TRIM40 (NM_138700)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TRIM40
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRIM40
    Sirion Biotech Customized lentivirus for stable overexpression of TRIM40 
                         Customized lentivirus expression plasmids for stable overexpression of TRIM40 
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for TRIM40
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TRIM40
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRIM40
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRIM40

    Additional mRNA sequence: BC060785.1 

    3 DOTS entries:

    DT.97782817  DT.100799887  DT.100747193 

    5 AceView cDNA sequences:

    BC060785 AF489517 CR597973 NM_138700 CR598345 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TRIM40 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATCCTCACCT
    TRIM40 Expression
    About this image


    See TRIM40 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TRIM40

    SOURCE GeneReport for Unigene cluster: Hs.509439

    UniProtKB/Swiss-Prot: TRI40_HUMAN, Q6P9F5
    Tissue specificity: Highly expressed in normal gastrointestinal epithelia but that is down-regulated in
    gastrointestinal carcinomas and chronic inflammatory lesions of the gastrointestinal tract

        SABiosciences Expression via Pathway-Focused PCR Array including TRIM40: 
              Ubiquitin Ligases in human mouse rat

    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for TRIM40
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TRIM40
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRIM40
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIM40

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for TRIM40 gene from 2/6 species (see all 6)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Trim401 , 5 tripartite motif-containing 401, 5 79.04(n)1
    70.3(a)1
      17 (19.16 cM)5
    1953591  NM_001033235.31  NP_001028407.11 
     368815985 
    zebrafish
    (Danio rerio)
    Actinopterygii TRIM406
    tripartite motif containing 40
    17(a)
    1 ↔ 1
    3(7016465-7061171)


    ENSEMBL Gene Tree for TRIM40 (if available)
    TreeFam Gene Tree for TRIM40 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TRIM40 gene
    2 SIMAP similar genes for TRIM40 using alignment to 5 protein entries:     TRI40_HUMAN (see all proteins):
    BRCA1    TRIM39

    TRIM40 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/493 SNPs in TRIM40 are shown (see all 493)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs93939911,2
    C,F,H--30102641(+) tgttgG/Atgatt 1 -- us2k1 tfbs34Minor allele frequency- A:0.04NS EA 420
    rs121944851,2
    --30102752(+) tttggA/Gaggcc 1 -- us2k10--------
    rs1856468741,2
    --30102761(+) CCAAGC/GCAGGC 1 -- us2k10--------
    rs1498334911,2
    --30102821(+) ACCCCA/GTCTCT 1 -- us2k10--------
    rs1422934941,2
    --30102906(+) GAGATA/TCGCTG 1 -- us2k10--------
    rs1408532471,2
    --30102907(+) AGATTA/CGCTGG 1 -- us2k10--------
    rs1901707441,2
    --30102922(+) TGGGAA/GGCAGA 1 -- us2k10--------
    rs598429911,2
    --30102923(+) GGGAGG/TCAGAG 1 -- us2k10--------
    rs1431545671,2
    --30102926(+) AGGCAC/GAGGTT 1 -- us2k10--------
    rs30946771,2
    C,A--30102958(-) TGGAGT/AGCAAC 1 -- us2k19Minor allele frequency- A:0.00NA WA CSA 16

    HapMap Linkage Disequilibrium report for TRIM40 (30103885 - 30116512 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for TRIM40:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2731777CNV Deletion23290073

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing TRIM40
    DNA2.0 Custom Variant and Variant Library Synthesis for TRIM40

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    3 diseases for TRIM40:    About MalaCards
    multiple sclerosis    systemic lupus erythematosus    lupus erythematosus


    TRIM40 for disorders           About GeneDecksing

    Genetic Association Database (GAD): TRIM40
    Human Genome Epidemiology (HuGE) Navigator: TRIM40 (3 documents)

    Export disorders for TRIM40 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TRIM40 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with TRIM40)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. TRIM40 promotes neddylation of IKKI^ and is downregula ted in gastrointestinal cancers. (PubMed id 21474709)1, 2 Noguchi K....Hatakeyama S. (2011)
    2. A major histocompatibility Class I locus contributes to multiple sclerosis susceptibility independently from HLA-DRB1*15:01. (PubMed id 20593013)1, 4 Cree B.A.... . (2010)
    3. High-density SNP screening of the major histocompatib ility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PubMed id 19851445)1, 4 Barcellos L.F....Criswell L.A. (2009)
    4. Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity. (PubMed id 16702430)1, 2 Shiina T.... Bahram S. (2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
    7. Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. (PubMed id 19010793)4 Baranzini S.E....Oksenberg J.R. (2008)
    8. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)2 Mungall A.J.... Beck S. (2003)
    9. Cluster of TRIM genes in the human MHC class I region sharing the B30.2 domain. (PubMed id 12622776)2 Meyer M....Trowsdale J. (2003)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 135644 HGNC: 18736 AceView: TRIM40 Ensembl:ENSG00000204614 euGenes: HUgn135644
    ECgene: TRIM40 H-InvDB: TRIM40

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TRIM40 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TRIM40 gene:
    Search GeneIP for patents involving TRIM40

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
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     Regulatory tfbs in TRIM40 promoter
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     Proteins for TRIM40
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     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRIM40
     inGenious Targeting Laboratory - Custom generated mouse model solutions for TRIM40
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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