Aliases for TRIM40 Gene
External Ids for TRIM40 Gene
Previous GeneCards Identifiers for TRIM40 Gene
This gene encodes a member of the tripartite motif (TRIM) protein family. The encoded protein may play a role as a negative regulator against inflammation and carcinogenesis in the gastrointestinal tract. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Feb 2014]
GeneCards Summary for TRIM40 Gene
TRIM40 (Tripartite Motif Containing 40) is a Protein Coding gene. GO annotations related to this gene include nucleotide binding.
UniProtKB/Swiss-Prot for TRIM40 Gene
May function as an E3 ubiquitin-protein ligase of the NEDD8 conjugation pathway. Promotes neddylation of IKBKG/NEMO, stabilizing NFKBIA, and inhibiting of NF-kappaB nuclear translocation and activity.