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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TRIM4 Gene

protein-coding   GIFtS: 47
GCID: GC07M099474

Tripartite Motif Containing 4

(Previous name: tripartite motif-containing 4)
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Tripartite Motif Containing 41 2     RING Finger Protein 872 3
Tripartite Motif-Containing 41 2     Tripartite Motif Protein TRIM41
Tripartite Motif Protein 41 2     Tripartite Motif-Containing Protein 42
RNF872 3     

External Ids:    HGNC: 162751   Entrez Gene: 891222   Ensembl: ENSG000001468337   UniProtKB: Q9C0373   

Export aliases for TRIM4 gene to outside databases

Previous GC identifers: GC07M098022 GC07M099085 GC07M099099 GC07M099133 GC07M099134 GC07M099325 GC07M094123


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TRIM4 Gene:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three
zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes
to cytoplasmic bodies. Its function has not been identified. Alternatively spliced transcript variants that
encode different isoforms have been described.(provided by RefSeq, Jul 2010)

GeneCards Summary for TRIM4 Gene: 
TRIM4 (tripartite motif containing 4) is a protein-coding gene. Diseases associated with TRIM4 include dermatophytosis. GO annotations related to this gene include zinc ion binding. An important paralog of this gene is TRIM7.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NT_007933.15  NC_018918.2  NT_079595.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TRIM4 gene promoter:
         HFH-3   SRF   Max1   Spz1   SRF (504 AA)   GATA-1   FOXI1   CP2   FOXJ2 (long isoform)   FOXJ2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTRIM4 promoter sequence
   Search SABiosciences Chromatin IP Primers for TRIM4

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRIM4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q22-q31.1   Ensembl cytogenetic band:  7q22.1   HGNC cytogenetic band: 7q22-q31.1

TRIM4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TRIM4 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M099474:  view genomic region     (about GC identifiers)

Start:
99,474,581 bp from pter      End:
99,517,223 bp from pter
Size:
42,643 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 98,848,146-98,877,343     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: TRIM4_HUMAN, Q9C037 (See protein sequence)
Recommended Name: Tripartite motif-containing protein 4  
Size: 500 amino acids; 57461 Da
Secondary accessions: A4D298 Q75MK1 Q96F06 Q9C036
Alternative splicing: 3 isoforms:  Q9C037-1   Q9C037-2   Q9C037-3   

Explore the universe of human proteins at neXtProt for TRIM4: NX_Q9C037

Explore proteomics data for TRIM4 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9C037

  • TRIM4 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TRIM4 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_148977.2  NP_149082.1  

    ENSEMBL proteins: 
     ENSP00000396229   ENSP00000348216   ENSP00000275736   ENSP00000346186  

    Human Recombinant Protein Products for TRIM4: 
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    OriGene MassSpec for TRIM4 
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    GenScript Custom Purified and Recombinant Proteins Services for TRIM4
    Novus Biologicals TRIM4 Protein
    Novus Biologicals TRIM4 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TRIM4 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005737cytoplasm IDA--
    GO:0005886plasma membrane IDA--

    TRIM4 for ontologies           About GeneDecksing



    TRIM4 Antibody Products: 
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    Assay Products for TRIM4: 
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    Cloud-Clone Corp. ELISAs for TRIM4 
    Cloud-Clone Corp. CLIAs for TRIM4


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    TRIM: Tripartite motif containing / Tripartite motif containing
    RNF: RING-type (C3HC4) zinc fingers

    5/9 InterPro protein domains (see all 9):
     IPR017907 Znf_RING_CS
     IPR001841 Znf_RING
     IPR001870 B30.2/SPRY
     IPR003877 SPRY_rcpt
     IPR000315 Znf_B-box

    Graphical View of Domain Structure for InterPro Entry Q9C037

    ProtoNet protein and cluster: Q9C037

    3 Blocks protein domains:
    IPB000315 B-box zinc finger signature
    IPB001841 Zn-finger
    IPB003879 Butyrophylin C-terminal DUF signature


    UniProtKB/Swiss-Prot: TRIM4_HUMAN, Q9C037
    Similarity: Belongs to the TRIM/RBCC family
    Similarity: Contains 1 B box-type zinc finger
    Similarity: Contains 1 B30.2/SPRY domain
    Similarity: Contains 1 RING-type zinc finger


    TRIM4 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--
    GO:0046872metal ion binding ----
         
    TRIM4 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for TRIM4:
     Decreased Salmonella enterica   Decreased Wnt reporter activit 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for TRIM4 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TRIM4

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TRIM4 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TRIM4 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TRIM4
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate TRIM4
    SwitchGear 3'UTR luciferase reporter plasmidTRIM4 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TRIM4
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    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector: TRIM4 (NM_017583)
    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRIM4
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                         Customized lentivirus expression plasmids for stable overexpression of TRIM4 

    Cell Line
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    Search LifeMap BioReagents cell lines for TRIM4
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIM4


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TRIM4

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for TRIM4 (ENSP000003482164) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MDM2ENSP000004172814STRING: ENSP00000417281
    TRIM41ENSP000003208694STRING: ENSP00000320869
    SUMO1ENSP000003760764STRING: ENSP00000376076
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0070206protein trimerization IDA17156811

    TRIM4 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TRIM4

    Search CenterWatch for drugs/clinical trials and news about TRIM4

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TRIM4 gene (2 alternative transcripts): 
    NM_033017.3  NM_033091.2  

    Unigene Cluster for TRIM4:

    Tripartite motif containing 4
    Hs.50749  [show with all ESTs]
    Unigene Representative Sequence: NM_033017
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000447480 ENST00000355947(uc003usd.3) ENST00000349062(uc003use.3 uc011kjc.2)
    ENST00000354241(uc003usf.3) ENST00000496896
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TRIM4
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate TRIM4
    SwitchGear 3'UTR luciferase reporter plasmidTRIM4 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TRIM4
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TRIM4
    Clone
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    OriGene clones in human, mouse for TRIM4 (see all 10)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TRIM4 (NM_017583)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TRIM4
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRIM4
    Sirion Biotech Customized lentivirus for stable overexpression of TRIM4 
                         Customized lentivirus expression plasmids for stable overexpression of TRIM4 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for TRIM4
    OriGene qSTAR qPCR primer pairs in human, mouse for TRIM4
    SABiosciences RT2 qPCR Primer Assay in human, mouse / rat TRIM4
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRIM4
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRIM4

    Additional mRNA sequence: 

    AF220023.1 AF220024.1 AK092892.1 AK293565.1 BC011763.2 BC025949.1 

    8 DOTS entries:

    DT.210668  DT.100814118  DT.95367251  DT.100701833  DT.121107628  DT.91656001  DT.91728902  DT.100674425 

    24/144 AceView cDNA sequences (see all 144):

    BU741082 AA732360 AI004200 N38858 CA489456 BM726767 AW614857 BQ186783 
    BQ632397 AW003996 BU608172 BM683487 BC025949 BI966807 BC011763 AW629620 
    AA913795 BE503987 AA722712 CR609720 CB154036 AA370143 BG250063 BF109577 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TRIM4 expression in normal human tissues (normalized intensities)      TRIM4 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    TRIM4 Expression
    About this image


    TRIM4 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/37 selected tissues (see all 37) fully expand
     
     Uterus (Reproductive System)    fully expand to see all 5 entries
             uterus, post-menopause ; glandular cells   
     
     Testis (Reproductive System)    fully expand to see all 4 entries
             Leydig Cells Testis Interstitium
             seminal vesicle ; glandular cells   
     
     Uncategorized (Uncategorized)    fully expand to see all 4 entries
             PureStem progenitor F15
     
     Colon (Gastrointestinal Tract)    fully expand to see all 3 entries
             rectum ; glandular cells   
     
     Tonsil (Hematopoietic System)    fully expand to see all 3 entries
             tonsil ; squamous epithelial cells   

    See TRIM4 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TRIM4

    SOURCE GeneReport for Unigene cluster: Hs.50749
        SABiosciences Expression via Pathway-Focused PCR Array including TRIM4: 
              Ubiquitin Ligases in human mouse rat

    Primer
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRIM4
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIM4

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of mammals.

    Orthologs for TRIM4 gene from 1/3 species (see all 3)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    dog
    (Canis familiaris)
    Mammalia TRIM41 tripartite motif containing 4 85.3(n)
    78.27(a)
      608654  XM_845745.1  XP_850838.1 


    ENSEMBL Gene Tree for TRIM4 (if available)
    TreeFam Gene Tree for TRIM4 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TRIM4 gene
    TRIM72  TRIM262  TRIM392  TRIM342  TRIM272  TRIM582  TRIM682  TRIM102  
    TRIM152  TRIM602  TRIM222  TRIM172  TRIM52  TRIM62  TRIM6-TRIM342  TRIM212  
    TRIM382  TRIM112  TRIM39-RPP212  
    7 SIMAP similar genes for TRIM4 using alignment to 2 protein entries:     TRIM4_HUMAN (see all proteins):
    TRIM41    TRIM17    TRIM11    TRIM6    TRIM58    TRIM39
    TRIM21

    TRIM4 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    472/609 SNPs in TRIM4 are shown (see all 609)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1145725561,2
    F--99487544(+) CAATCC/TAATCT 2 -- ds50011Minor allele frequency- T:0.01WA 118
    rs1839298961,2
    --99487711(+) GTTTAA/CATCTG 2 -- ds50010--------
    rs1386366631,2
    --99487766(+) TCAACA/GTATGT 2 -- ds50010--------
    rs2011830431,2
    C--99487812(+) ATCCT-/GGGAAG 2 -- ds50010--------
    rs1871369921,2
    --99487837(+) GAAACC/TGTTGA 2 -- ds50010--------
    rs1165263451,2
    F--99487986(+) CCATTA/GTTCGG 2 -- ds50011Minor allele frequency- G:0.03WA 118
    rs1918647051,2
    --99488238(+) AACACA/GTGAAC 2 -- ut310--------
    rs1852173911,2
    --99488270(+) TCTCAC/GGTATA 2 -- ut310--------
    rs1898473701,2
    --99488279(+) TAAGGC/GAGAGC 2 -- ut310--------
    rs2022450141,2
    C--99488303(+) CCCAT-/GGACA 
     CAAAAAA
    GGGAA
    2 -- cds10--------
    rs1820660321,2
    --99488464(+) TAGAAC/TAAACC 2 -- ut310--------
    rs25720101,2
    C,F,A,H--99488543(-) TTTCAA/GTAAAG 2 -- ut3115Minor allele frequency- G:0.44NS EA NA WA CSA 788
    rs1427782771,2
    C--99488580(+) TAGTAA/GTGCAT 2 -- ut310--------
    rs1507433211,2
    --99488603(+) TATACC/TTTTTG 2 -- ut310--------
    rs603057551,2
    C,F--99488617(+) CTTACA/TAACTT 2 -- ut312Minor allele frequency- T:0.08WA 120
    rs1853765391,2
    C--99488745(+) ACTGAA/GGAAAA 2 -- ut310--------
    rs1154102081,2
    C,F--99488757(+) ATACAC/TAGTAT 2 -- ut311Minor allele frequency- T:0.04WA 118
    rs1379634431,2
    C--99488898(+) AGTTAA/CTCTAA 2 -- ut310--------
    rs10487051,2
    C,F,O,A,H--99488940(-) GAAAGA/TCAAAT 2 -- ut3121Minor allele frequency- N:0.00MN EA NA NS WA CSA 1192
    rs126660071,2
    C,F,H--99488969(+) TGAGAG/ATCATA 2 -- ut31 ese34Minor allele frequency- A:0.00NS EA 418
    rs25720091,2
    C,F,O,A,H--99489005(-) AAATAC/TCTTTT 2 -- ut3132Minor allele frequency- T:0.39NS NA EA WA CSA 2592
    rs1808078511,2
    C--99489018(+) CAAGCA/GTTCAA 2 -- ut310--------
    rs1495110141,2
    --99489137(+) GCAACA/GTAGGC 2 -- ut310--------
    rs761230231,2
    C,F--99489230(+) ACTGGA/GTAGAA 2 -- ut311Minor allele frequency- G:0.05EA 120
    rs1440096551,2
    --99489289(+) ACTGCA/GGGATG 2 -- ut310--------
    rs737116611,2
    C--99489361(+) TAAAAT/CTGTCT 2 -- ut312Minor allele frequency- C:0.04WA 120
    rs737116621,2
    C,F--99489426(+) TTTCAA/GCAATT 2 -- ut312Minor allele frequency- G:0.02WA 120
    rs2006854561,2
    C--99489439(+) ACAACA/GGCAAC 2 -- ut310--------
    rs1399801431,2
    --99489450(+) AAAAAC/TTCTGT 2 -- ut310--------
    rs172775461,2
    C,F,H--99489571(+) GTCTTG/AGAAAA 2 -- ut31 ese316Minor allele frequency- A:0.02NA NS EA 1756
    rs1434681491,2
    C--99489595(+) CTCCAC/TTGGCC 2 -- ut310--------
    rs766658761,2
    C,F--99489857(+) GAGGCG/ATGAGA 4 /R /C mis11Minor allele frequency- A:0.03EA 120
    rs339985961,2,4
    C,F--99489868(-) TTGTTC/GTTCTG 4 S C mis112Minor allele frequency- G:0.06NA NS EA CSA WA EU 6615
    rs3749638701,2
    C--99489906(+) ACAGCA/GCTGTA 4 S syn10--------
    rs785998701,2
    C,F--99490052(+) CACATC/TTGGGG 4 N D mis12Minor allele frequency- T:0.00NA EU 5409
    rs1463160521,2
    C,F--99490086(+) CCCATG/TACGTC 4 V syn11Minor allele frequency- T:0.00NA 4552
    rs354329461,2,4
    C,F--99490190(-) ACTTAC/TCCTGT 4 P S mis112Minor allele frequency- T:0.06NA NS EA CSA WA EU 6617
    rs2015108081,2
    C--99490258(+) TCCATA/GCTGAA 4 A V mis10--------
    rs1395061271,2
    C--99490274(+) CACTGG/TCCAAG 4 T P mis10--------
    rs2005341981,2
    C--99490305(+) TTCACA/GTATCT 4 Y syn10--------
    rs344023971,2
    C,F--99490323(-) GTCTTC/TTCCCA 4 F syn14Minor allele frequency- T:0.00NA WA 4730
    rs1488124881,2
    C,F--99490329(+) AAGACG/AAGTTT 4 /L syn12Minor allele frequency- A:0.00NA EU 5849
    rs69577181,2
    C,F,A,H--99490501(+) CCAACT/AGATCC 2 -- int115Minor allele frequency- A:0.19NS EA NA CSA WA 928
    rs1884644881,2
    --99490510(+) CCTCAC/GCCAGG 2 -- int10--------
    rs1813142671,2
    --99490652(+) AGATCA/CCTGGA 2 -- int10--------
    rs1115265711,2
    F--99490664(+) GTCACG/AAGAGT 2 -- int11Minor allele frequency- A:0.50CSA 2
    rs1866251101,2
    --99490689(+) CAACAC/TGGCGA 2 -- int10--------
    rs1914809661,2
    --99490700(+) AACCCC/TGTCTC 2 -- int10--------
    rs1837042381,2
    --99490733(+) ACAAAA/CAAAAA 2 -- int10--------
    rs1510632461,2
    --99490740(+) AAAAAA/GCTGGC 2 -- int10--------
    rs1871443451,2
    --99490788(+) GGGAGA/GCTGAG 2 -- int10--------
    rs563377651,2
    C,F--99490795(+) TGAGGG/CAGAAG 2 -- int11Minor allele frequency- C:0.50WA 2
    rs25720081,2
    C,F,O,H--99490956(-) GGCTGA/TTTGTG 2 -- int119Minor allele frequency- T:0.44NS EA NA WA CSA 934
    rs133103261,2
    --99490993(+) TCTCAC/TGTTGA 2 -- int10--------
    rs678424921,2
    C--99490994(+) TCACG-/ATTTGAA 2 -- int10--------
    rs1479254901,2
    --99491055(+) CACAGA/GTGTCA 2 -- int10--------
    rs1418900071,2
    C--99491186(+) ACTCTC/TGGGAC 2 -- int10--------
    rs1471139381,2
    --99491216(+) ACATCG/TTGCCT 2 -- int10--------
    rs1912095391,2
    --99491244(+) GTCAGA/GGTCCC 2 -- int10--------
    rs1386920691,2
    --99491318(+) CTAGTC/TAGTCA 2 -- int10--------
    rs1488271901,2
    --99491338(+) ACCAAC/TTCTAC 2 -- int10--------
    rs1175783281,2
    C,F--99491545(+) AGTTTG/AACAAA 2 -- int11Minor allele frequency- A:0.02NA 120
    rs1821801371,2
    --99491821(+) TGAGAC/GACATT 2 -- int10--------
    rs1869217111,2
    C--99491853(+) GTGACA/GTCTTT 2 -- int10--------
    rs1434213301,2
    --99492037(+) TAATCC/TCAATG 2 -- int10--------
    rs283608021,2
    F--99492053(+) GGAGGC/TCAAGG 2 -- int10--------
    rs1828539421,2
    --99492160(+) TGGCGC/TGCACC 2 -- int10--------
    rs1882727331,2
    --99492161(+) GGCGCA/GCACCT 2 -- int10--------
    rs2016442031,2
    --99492286(+) TCCAT-/CCCCCC 2 -- int10--------
    rs25720071,2
    C,A--99492296(-) tttttT/Gggggg 2 -- int1 trp39Minor allele frequency- G:0.36NA WA CSA EA 369
    rs1999380531,2
    --99492307(+) AAAAA-/GAAAAG 2 -- int10--------
    rs1173846381,2
    F--99492403(+) TCTCTA/GTCTTC 2 -- int11Minor allele frequency- G:0.01EA 120
    rs1480135461,2
    C--99492686(+) GCAATA/GATTTC 2 -- int10--------
    rs763841581,2
    F--99492705(+) TTTTTA/TTTATT 2 -- int11Minor allele frequency- T:0.07NA 120
    rs25279221,2
    C,F,A,H--99492756(-) gacacT/Cagaga 2 -- int118Minor allele frequency- C:0.49NS EA NA WA CSA 1154
    rs1180335171,2
    C,F--99493042(+) ACATAC/TTCTGA 2 -- int11Minor allele frequency- T:0.02NA 120
    rs1928232351,2
    --99493070(+) AATTTC/GACACT 2 -- int10--------
    rs1854497701,2
    --99493072(+) TTTGAC/TACTTG 2 -- int10--------
    rs775779771,2
    F--99493195(+) ATAATA/GTTATT 2 -- int11Minor allele frequency- G:0.01NA 120
    rs1893156651,2
    --99493246(+) CTAAAA/CATTAT 2 -- int10--------
    rs25279211,2
    C,F--99493270(-) gtttgG/Cagttt 2 -- int115Minor allele frequency- C:0.43NA WA CSA EA 516
    rs1416649991,2
    --99493307(+) TTGCAG/TCTCTA 2 -- int10--------
    rs748925481,2
    F--99493407(+) AGGATA/GTAACA 2 -- int11Minor allele frequency- G:0.01WA 118
    rs1158199781,2
    C,F--99493432(+) TAATAT/GCCTTT 2 -- int11Minor allele frequency- G:0.01WA 118
    rs1926212631,2
    --99493462(+) TACTAA/CTATAC 2 -- int10--------
    rs125369451,2
    C,F,H--99493472(+) CCCACT/CCCAGA 2 -- int15Minor allele frequency- C:0.03NS EA WA 538
    rs1460106131,2
    C--99493617(+) TTAGCA/GCATGC 2 -- int10--------
    rs77875251,2
    C,F,H--99493660(+) gattaG/Aatttg 2 -- int119Minor allele frequency- A:0.26NS EA NA CSA WA 2094
    rs1386646061,2
    --99493810(+) GTTTAC/TGGTAT 2 -- int10--------
    rs25720061,2
    C,F,A,H--99493811(-) GatacT/Cataaa 2 -- int131Minor allele frequency- C:0.45MN NS EA NA WA CSA 2622
    rs25279201,2
    C,F,A--99493880(-) ttctaC/Gttgga 2 -- int116Minor allele frequency- G:0.31MN NA WA CSA EA 702
    rs1418946951,2
    --99494018(+) TCAAGG/TCCCTT 2 -- int10--------
    rs25720051,2
    C,F,H--99494030(-) taaccT/Cgaatc 2 -- int117Minor allele frequency- C:0.44NS EA NA WA CSA 793
    rs1835821881,2
    --99494232(+) GTACTA/GAAATC 2 -- int10--------
    rs102459801,2
    H--99494280(+) ttggaG/Aaaaat 2 -- int14Minor allele frequency- A:0.00NS EA 418
    rs1462757371,2
    --99494315(+) TCAGGA/GGAGAA 2 -- int10--------
    rs1462883861,2
    C--99494369(+) CCCAA-/T/TT  
            
    TAGCC
    2 -- int10--------
    rs102460911,2
    C,H--99494372(+) caataG/Accact 2 -- int16Minor allele frequency- A:0.00NS EA NA 422
    rs1880212041,2
    --99494394(+) GTGGGG/TCCCAC 2 -- int10--------
    rs599963561,2
    C--99494505(+) AGCTGC/TAGTTG 2 -- int12Minor allele frequency- T:0.10CSA WA 120
    rs1393601131,2
    --99494508(+) TGCAGC/TTGGCC 2 -- int10--------
    rs25279191,2
    C,F,A,H--99494513(-) TGGCCA/GGCCAA 2 -- int119Minor allele frequency- G:0.44NA NS EA WA CSA 930
    rs1499883681,2
    --99494539(+) AGAGCA/GGCCCC 2 -- int10--------
    rs1809982041,2
    C--99494549(+) CCAAGG/TTTGAG 2 -- int10--------
    rs125376761,2
    C,F,H--99494595(+) tgagcT/Cgcaac 2 -- int14Minor allele frequency- C:0.00NS EA 416
    rs778349811,2
    F--99494608(+) GGGAGA/GTATTA 2 -- int12Minor allele frequency- G:0.05WA NA 238
    rs1861748171,2
    --99494668(+) GACACC/TGGTTT 2 -- int10--------
    rs1144084061,2
    F--99494680(+) TTGCAT/CAGCCT 2 -- int11Minor allele frequency- C:0.08WA 118
    rs1487523091,2
    --99494690(+) TGTTTA/GAAGGG 2 -- int10--------
    rs1899962411,2
    --99494826(+) CCATCC/TTCTCA 2 -- int10--------
    rs1817051421,2
    --99495110(+) AATTAA/CCCTGA 2 -- int10--------
    rs1870762251,2
    --99495167(+) CCTCAC/TAAATA 2 -- int10--------
    rs734054191,2
    C,F--99495238(+) CACTCG/CATGGG 2 -- int11Minor allele frequency- C:0.50WA 2
    rs25279181,2
    C,F,A,H--99495472(-) GCACCA/CCCCCT 2 -- int115Minor allele frequency- C:0.33NS EA NA WA CSA 774
    rs761085801,2
    F--99495732(+) GCATGA/GTAAGT 2 -- int11Minor allele frequency- G:0.07NA 120
    rs570280431,2
    C,F--99495831(+) ATGGGA/GGCAGG 2 -- int12Minor allele frequency- G:0.05WA 120
    rs1909621951,2
    --99495871(+) ATACAC/TGATGG 2 -- int10--------
    rs737116661,2
    C--99495933(+) ATGTAC/TTGAAA 2 -- int12Minor allele frequency- T:0.05WA 120
    rs1165991831,2
    C,F--99495992(+) ACCCCC/TACAGC 2 -- int11Minor allele frequency- T:0.01WA 118
    rs1832637741,2
    --99496023(+) ATAGCC/GAATAA 2 -- int10--------
    rs1455140181,2
    --99496034(+) TATGTG/TGCTAG 2 -- int10--------
    rs1865027911,2
    --99496041(+) CTAGGA/GTGGCA 2 -- int10--------
    rs1896637041,2
    --99496092(+) GGGATA/GGCTAC 2 -- int10--------
    rs126703511,2
    C,F,H--99496155(+) atgcaC/Gctggg 2 -- int14Minor allele frequency- G:0.01NS EA 378
    rs1410828981,2
    --99496164(+) GGGTCA/GTCTTC 2 -- int10--------
    rs28970311,2
    F,H--99496177(+) CTGCCG/AGACAC 2 -- int15Minor allele frequency- A:0.02NS EA NA 528
    rs1503014371,2
    C--99496251(+) AAGTGG/TGCATT 2 -- int10--------
    rs1828859871,2
    --99496415(+) TAAAAC/TCAAAT 2 -- int10--------
    rs1879458741,2
    --99496483(+) AACCCA/GTATTT 2 -- int10--------
    rs8927521,2
    C,F,A,H--99496667(-) ccccaC/Tattct 2 -- int110Minor allele frequency- T:0.03NS EA NA WA 786
    rs1930061061,2
    --99496704(+) GTGTAC/TGGCAG 2 -- int10--------
    rs1833448171,2
    C--99496779(+) TATTCA/GGAGTT 2 -- int10--------
    rs1448854951,2
    C--99496809(+) AGTGGC/TCAACC 2 -- int10--------
    rs1874903471,2
    --99497121(+) GTCAGC/TAGGGG 2 -- int10--------
    rs1921691501,2
    --99497188(+) TCACAC/TATGAG 2 -- int10--------
    rs774732981,2
    C--99497202(+) TGTATA/CATAGT 2 -- int10--------
    rs769728591,2
    F--99497267(+) TAAATA/GTAAGT 2 -- int12Minor allele frequency- G:0.05WA NA 238
    rs1846047241,2
    --99497289(+) CCATAC/TTTTGT 2 -- int10--------
    rs1893481961,2
    --99497322(+) GGGTTC/TTCCAA 2 -- int10--------
    rs1921814271,2
    --99497483(+) ATCACA/TGCTCA 2 -- int10--------
    rs1490672051,2
    C--99497501(+) CTCAAA/CCTCCT 2 -- int10--------
    rs1846581021,2
    --99497585(+) TTTATG/TTTTTG 2 -- int10--------
    rs1894754341,2
    --99497703(+) CACACC/GCAGCC 2 -- int10--------
    rs1815259341,2
    C--99497767(+) AGTCCA/GAATCT 2 -- int10--------
    rs1842290321,2
    --99497869(+) CCAAGA/GTAGTA 2 -- int10--------
    rs25279161,2
    C,F,A,H--99497957(-) ccttcT/Ataatg 2 -- int115Minor allele frequency- A:0.48NA WA CSA EA 509
    rs1446637121,2
    --99498003(+) CTTATC/GCAAAA 2 -- int10--------
    rs25279151,2
    C,A,H--99498018(-) tttttG/Ttgagg 2 -- int110Minor allele frequency- T:0.42NA WA CSA EA 371
    rs1889547131,2
    --99498081(+) TGATGC/TATAAA 2 -- int10--------
    rs1816075071,2
    --99498095(+) ACCATC/TGCAAT 2 -- int10--------
    rs25279141,2
    C,F,A,H--99498145(-) TGACAT/CGAATA 2 -- int115Minor allele frequency- C:0.42NS EA NA WA CSA 784
    rs1863018771,2
    --99498222(+) CTGAAC/GGACTT 2 -- int10--------
    rs1173601931,2
    F--99498471(+) TCTCCC/GCTGGT 2 -- int11Minor allele frequency- G:0.02NA 120
    rs108081141,2
    C,F,A,H--99498499(+) TTTTAT/ACACTG 2 -- int116Minor allele frequency- A:0.44NS EA NA WA CSA 756
    rs1398397421,2
    C--99498538(+) ATATT-/TTTCTTCAT
    ATTTCTCAGGG
    TTTCT
    2 -- int10--------
    rs1924713831,2
    --99498541(+) ATTTTA/TCTTCA 2 -- int10--------
    rs2005201501,2
    C--99498556(+) TCTCAG/TACTCA 2 -- int10--------
    rs1417508011,2
    --99498881(+) GCCTTA/TATCAC 2 -- int10--------
    rs737116711,2
    C,F--99498913(+) GATCTG/AGTCTC 2 -- int13Minor allele frequency- A:0.05WA CSA 122
    rs1454194081,2
    --99498989(+) ATCTGC/TGTCAA 2 -- int10--------
    rs1480638471,2
    --99499011(+) TTTCAA/GTTGAT 2 -- int10--------
    rs1808452671,2
    --99499038(+) GGGTCA/GCTGCT 2 -- int10--------
    rs1417779221,2
    --99499065(+) TGCATA/GTTTGA 2 -- int10--------
    rs1862031881,2
    C--99499109(+) GGTGCC/TCTTTT 2 -- int10--------
    rs1911209151,2
    --99499196(+) TGGGTC/TTTGCT 2 -- int10--------
    rs1831415581,2
    --99499286(+) GAGTAC/TGCTAC 2 -- int10--------
    rs1870976311,2
    --99499333(+) GATAGA/GAACTG 2 -- int10--------
    rs1506218901,2
    --99499402(+) CTTCTA/GTCTCC 2 -- int10--------
    rs1903256131,2
    --99499712(+) TCACCA/GTCCTT 2 -- int10--------
    rs1176742781,2
    C,F--99499799(+) GTTGCT/CGCAGA 2 -- int12Minor allele frequency- C:0.03NA EU 689
    rs755718981,2
    C--99499800(+) TTGCTG/TCAGAC 2 -- int10--------
    rs1829268071,2
    --99499819(+) AACTCA/GTTTAT 2 -- int10--------
    rs25279131,2
    C,F,A,H--99499872(-) caaacA/Taaaaa 2 -- int112Minor allele frequency- T:0.42NA WA CSA EA 374
    rs25279121,2
    C,F,A,H--99500042(-) aatacA/Caaaat 2 -- int15Minor allele frequency- C:0.28NA EA 128
    rs1396911781,2
    --99500058(+) AGAGAC/TAGGGT 2 -- int10--------
    rs1877393831,2
    --99500114(+) ATCCGA/CCTGCC 2 -- int10--------
    rs798103491,2
    F--99500323(+) TTCCTC/GAAAAT 2 -- int14Minor allele frequency- G:0.04CSA WA NA EA 359
    rs1122216241,2
    C,F--99500405(+) TCTGCG/TTGAAA 2 -- int11Minor allele frequency- T:0.00CSA 1
    rs1932787431,2
    --99500450(+) CTAATA/CCCTCA 2 -- int10--------
    rs1170293191,2
    F--99500463(+) TCTCAA/GAACTG 2 -- int11Minor allele frequency- G:0.01EA 120
    rs25720041,2
    C,F,H--99500512(-) GAAGGG/TCTCTG 2 -- int1 trp36Minor allele frequency- T:0.00NS EA NA 418
    rs412809531,2
    C--99500597(+) TGTCTG/ATCTCT 2 -- int13Minor allele frequency- A:0.05CSA WA NA 240
    rs1399274141,2
    C--99500611(+) ATGTGC/TTTACG 2 -- int10--------
    rs1455819501,2
    C--99500677(+) AGTGCA/GTTAAA 2 -- int10--------
    rs617427501,2
    C,F--99500864(+) TTTCCT/GTCATC 4 /K /T mis16Minor allele frequency- G:0.02NS WA CSA NA EU 6039
    rs22477621,2
    C,F,A,H--99500899(-) GCTGTA/GAAGGT 4 V syn127Minor allele frequency- G:0.35NA NS EA WA CSA EU 8401
    rs22477611,2
    C,F,A,H--99500911(-) TATTCC/TCTTGA 4 S syn1 ese340Minor allele frequency- T:0.37NA NS EA WA CSA EU 9267
    rs1477113271,2
    C,F--99500926(+) ACATCC/GTGGAT 4 H Q mis11Minor allele frequency- G:0.00NA 4548
    rs2019551321,2
    --99500966(+) TCTTAA/GGGGAC 2 -- int10--------
    rs2010080721,2
    --99500968(+) TTAGGC/GGACAA 2 -- int10--------
    rs1159523431,2
    F--99501086(+) AGACCC/TCCATT 2 -- int11Minor allele frequency- T:0.01WA 118
    rs1128712931,2
    C,F--99501189(+) AACAGG/AAGTGC 2 -- int12Minor allele frequency- A:0.00CSA EU 1324
    rs1509415371,2
    C--99501200(+) ATACCG/TGGTCA 4 R syn10--------
    rs1390389071,2
    C,F--99501208(+) TCAACA/TCTTCT 4 E V mis11Minor allele frequency- T:0.00NA 4550
    rs1842503911,2
    C--99501244(+) ACATAA/CGCAAA 2 -- int10--------
    rs1407161381,2
    C--99501254(+) ATTACA/GAACCT 2 -- int10--------
    rs25720031,2
    C,F,O,A,H--99501313(-) GCAAAA/TGCAAC 2 -- int122Minor allele frequency- T:0.46NA NS EA WA CSA 1291
    rs1157024021,2
    F--99501375(+) GGTCCT/CTTCTT 2 -- int11Minor allele frequency- C:0.01WA 118
    rs1877346941,2
    --99501476(+) CCTGCC/TGGCCT 2 -- int10--------
    rs1924011711,2
    --99501522(+) GCGTGC/TCTTTT 2 -- int10--------
    rs1445616781,2
    --99501598(+) GCTTTC/TAAATT 2 -- int10--------
    rs1839809641,2
    --99501867(+) GGCAAC/TGTGTA 2 -- int10--------
    rs1467008241,2
    C--99501868(+) GCAACA/GTGTAT 2 -- int10--------
    rs1402701361,2
    --99501935(+) GACAAA/TTTCCA 2 -- int10--------
    rs571289061,2
    C,F--99501974(+) CCAACA/TCTCCT 2 -- int12Minor allele frequency- T:0.08WA 120
    rs78015681,2
    C,F,H--99502111(+) tgaatA/Gctagg 2 -- int17Minor allele frequency- G:0.10NS EA WA CSA 536
    rs795337521,2
    F--99502587(+) GGGGCG/AAAGTT 2 -- int12Minor allele frequency- A:0.06WA NA 238
    rs1454905381,2
    --99502613(+) GGTGCC/TACTGC 2 -- int10--------
    rs577437361,2
    C,F--99502674(+) AAAAA-/ATAGCT 2 -- int13Minor allele frequency- A:0.33NA CSA 6
    rs1380225481,2
    --99502778(+) AGATGA/CCATTT 2 -- int10--------
    rs1887110371,2
    --99502797(+) TCAGGA/GTGGCT 2 -- int10--------
    rs1174902361,2
    C,F--99503140(+) GAATAC/TGACAG 2 -- int11Minor allele frequency- T:0.03NA 120
    rs1142596661,2
    F--99503205(+) CTGAAG/CGCAGG 2 -- int11Minor allele frequency- C:0.02WA 118
    rs1495484541,2
    --99503258(+) AAGAGA/GTGCTG 2 -- int10--------
    rs771793111,2
    C,F--99503297(+) CAAAAA/GTGTCT 2 -- int11Minor allele frequency- G:0.03EA 120
    rs1431812331,2
    --99503412(+) CAAACA/GTAATG 2 -- int10--------
    rs119801791,2
    C,F,A,H--99503542(+) gcaggC/Tggatc 2 -- int14Minor allele frequency- T:0.38NA CSA 8
    rs25279111,2
    C,F,A,H--99503625(-) acaccC/Tggcta 2 -- int17Minor allele frequency- T:0.15NA WA CSA 13
    rs1815615151,2
    --99503641(+) CACACA/GCCTGT 2 -- int10--------
    rs1847145081,2
    --99503723(+) AGATCA/GCTCCA 2 -- int10--------
    rs1474499661,2
    --99503906(+) TTGGAC/TAGTAG 2 -- int10--------
    rs771171041,2
    C,F--99504076(+) TCCCAA/CAGTGC 2 -- int12Minor allele frequency- C:0.04CSA WA 120
    rs1902998021,2
    C--99504097(+) GACGTA/GAGCCA 2 -- int10--------
    rs756269241,2
    F--99504432(+) CCACCG/ACACTC 2 -- int11Minor allele frequency- A:0.05WA 118
    rs1825318071,2
    --99504633(+) GGTCAC/TGGGGT 2 -- int10--------
    rs1399988991,2
    C--99504963(+) CCTGAC/TCTCAG 2 -- int10--------
    rs1872732551,2
    --99504976(+) GATCCA/CCCCAC 2 -- int10--------
    rs25720021,2
    C,F,O,A,H--99505054(-) GGAAAC/TGATTA 2 -- int114Minor allele frequency- T:0.30NS NA WA CSA EA 748
    rs1909280921,2
    --99505106(+) CATTCC/TGCTGG 2 -- int10--------
    rs77814421,2
    C,F,A,H--99505223(+) CAACTG/ACATTG 2 -- int122Minor allele frequency- A:0.28NS EA NA WA 2526
    rs1439069021,2
    --99505226(+) CTGCAC/TTGCTT 2 -- int10--------
    rs1808599121,2
    --99505341(+) ATAATA/TACTAC 2 -- int10--------
    rs731566701,2
    --99505406(+) GCTTAC/TGAAAA 2 -- int10--------
    rs788570581,2
    F--99505410(+) ATGAAA/CAAAAA 2 -- int11Minor allele frequency- C:0.01WA 118
    rs1853168211,2
    --99505480(+) ATTCAC/TGTGAT 2 -- int10--------
    rs1506748481,2
    --99505496(+) GGAAAA/GAGAGG 2 -- int10--------
    rs734054311,2
    C,F--99505619(+) CAGAGG/AATATA 2 -- int12Minor allele frequency- A:0.08WA 120
    rs587504031,2
    C,F--99505905(+) AATTAT/CAAATG 2 -- int13Minor allele frequency- C:0.05WA CSA 122
    rs1902771841,2
    --99506049(+) GAATGA/GTGAAT 2 -- int10--------
    rs343955611,2
    C,F--99506148(+) CTAAAG/CACAAG 2 -- int14Minor allele frequency- C:0.04NA 126
    rs1999770561,2
    C--99506244(+) TCCCCC/TACCTC 4 V syn10--------
    rs2019659951,2
    --99506280(+) ATAGTC/TTGATT 4 Q syn10--------
    rs1398803721,2
    C,F--99506304(+) TTCTCA/GTTCAG 4 N syn12Minor allele frequency- G:0.01NA EU 5875
    rs3742622781,2
    C--99506311(+) TCAGCC/TCTTCT 4 K R mis10--------
    rs1472788161,2
    C,F--99506401(+) ACTCCG/ATGCTG 4 /T /M mis11Minor allele frequency- A:0.00NA 4550
    rs1498137941,2
    C--99506543(+) CTCTTA/GAAAAG 2 -- int10--------
    rs1448403851,2
    --99506603(+) CTTGAC/TAGCTC 2 -- int10--------
    rs1485778921,2
    C--99506701(+) CTACTA/GCTTAG 2 -- int10--------
    rs1874835851,2
    --99506754(+) GTGTGA/TGGGTG 2 -- int10--------
    rs721185211,2
    C--99506757(+) GAGGG-/GT/GTGT
    /GTGTGTGT
    TGTGT
    2 -- int10--------
    rs579606711,2
    C--99506781(+) GTGTG-/TGTGTG
    /TGTGTGTG
    CGTGT
    4 -- int1 cds11NA 2
    rs1916381271,2
    --99506783(+) TGTGCA/GTGTGT 2 -- int10--------
    rs669534351,2
    C,F--99506800(+) ATCCAG/TTCATC 2 -- int11Minor allele frequency- T:0.50NA 2
    rs734054341,2
    C,F--99506981(+) TATCCC/ACGTAT 2 -- int12Minor allele frequency- A:0.04WA 120
    rs1839368021,2
    --99507061(+) CAGAGC/GTTCTG 2 -- int10--------
    rs2011653251,2
    C--99507203(+) GTGGCA/GTTCTT 4 N syn10--------
    rs1887830021,2
    C--99507230(+) AAATGA/CATGAC 4 M I mis10--------
    rs1925558111,2
    --99507337(+) TCATCA/TTCTTT 2 -- int10--------
    rs2021733621,2
    C--99507346(+) TTTTTC/TTTTTT 2 -- int10--------
    rs1424770021,2
    --99507352(+) TTTTT-/GTTTTT 2 -- int10--------
    rs25720011,2
    C,F,A--99507353(-) AAAAAC/ACAAAA 2 -- int1 trp37Minor allele frequency- A:0.15NA WA CSA 13
    rs582429271,2
    C--99507373(+) TTTTT-/T/TT  
            
    GAGAC
    2 -- int11NA 2
    rs1403036821,2
    --99507561(+) TGTTGC/GCCAGG 2 -- int10--------
    rs1497164531,2
    C--99507661(+) CTTCA-/TTTTTTAA 2 -- int10--------
    rs1440397881,2
    --99507941(+) TAATGC/TTACTT 2 -- int10--------
    rs1839389311,2
    --99508034(+) AATTAC/GGAATT 2 -- int10--------
    rs1509948641,2
    --99508180(+) AACGTA/GTCTAT 2 -- int10--------
    rs780829591,2
    C,F--99508425(+) CAACAT/CTGACA 2 -- int11Minor allele frequency- C:0.03WA 118
    rs1408353651,2
    --99508501(+) ATGTTA/GGAGAA 2 -- int10--------
    rs1871437061,2
    --99508583(+) CTCAGC/TTGTGG 2 -- int10--------
    rs799155381,2
    C,F--99508651(+) AGCAGT/CGTGTA 2 -- int12Minor allele frequency- C:0.05WA NA 238
    rs731566711,2
    C--99508719(+) GACATC/TCAAGT 2 -- int10--------
    rs1918736391,2
    --99508724(+) CCAAGC/TGGATA 2 -- int10--------
    rs752279331,2
    F--99508741(+) CAATTA/GGAGTT 2 -- int11Minor allele frequency- G:0.07NA 120
    rs1386597651,2
    --99508802(+) GGCAGC/TTGGAG 2 -- int10--------
    rs1844764931,2
    --99509007(+) CTAGTA/GAATAG 2 -- int10--------
    rs1414056831,2
    --99509314(+) CACAAC/TATTAG 2 -- int10--------
    rs25720001,2
    C,F,A,H--99509324(-) cattcG/Acctgc 2 -- int127Minor allele frequency- A:0.28NS EA NA WA CSA 2774
    rs1901111971,2
    --99509448(+) ATAGAA/CCTGTA 2 -- int10--------
    rs1470459511,2
    C--99509575(+) CTATAC/GAAAAA 2 -- int10--------
    rs737116771,2
    C,F--99509698(+) CAGAAC/TGGTGG 2 -- int12Minor allele frequency- T:0.04WA 120
    rs1164971661,2
    F--99509742(+) TGGGAA/GAGGGC 2 -- int11Minor allele frequency- G:0.06WA 118
    rs1929503031,2
    --99509748(+) AGGGCA/GTGAAA 2 -- int10--------
    rs1382756831,2
    --99509855(+) TTTTAC/TCTCAA 2 -- int10--------
    rs1161122931,2
    F--99509938(+) AGCTTG/AAGGCC 2 -- int11Minor allele frequency- A:0.08WA 118
    rs754577551,2
    --99510154(+) CATATA/C/TAAAAA 2 -- int13NA WA 240
    rs1439392331,2
    --99510164(+) AAAAAA/TAATAA 2 -- int10--------
    rs342775971,2
    C--99510167(+) AAAAAA/TAATAC 2 -- int17Minor allele frequency- T:0.43NA WA CSA EA 365
    rs676700341,2
    C--99510167(-) TATTT-/A/TTTTTT 2 -- int11NA 2
    rs1855119421,2
    --99510220(+) GTATTC/TTGTTT 2 -- int10--------
    rs47274391,2
    C,F,A--99510234(+) ATTGAA/CTTTTA 2 -- int116Minor allele frequency- C:0.33NA EA WA CSA 874
    rs1442903241,2
    --99510243(+) TAAAAG/TCATCA 2 -- int10--------
    rs1148521141,2
    F--99510279(+) AGAGAG/AATACA 2 -- int11Minor allele frequency- A:0.01WA 118
    rs1483122961,2
    --99510342(+) CATGTA/GGGTAC 2 -- int10--------
    rs1904359751,2
    --99510415(+) AAATAA/GGAAAA 2 -- int10--------
    rs1808184481,2
    --99510480(+) TCTGTA/GCTATT 2 -- int10--------
    rs1851755691,2
    --99510515(+) ACATTA/GTATCA 2 -- int10--------
    rs102715941,2
    H--99510609(+) ACTGCC/TGCTTT 2 -- int14Minor allele frequency- T:0.00NS EA 420
    rs1884740551,2
    --99510685(+) GGACCA/CAGTTT 2 -- int10--------
    rs25719991,2
    C,F,H--99510850(-) TTCCAT/ACTGTG 2 -- int112Minor allele frequency- A:0.42NA WA CSA EA 374
    rs1810661611,2
    --99510995(+) ATTTTA/TAAAAT 2 -- int10--------
    rs1864504111,2
    --99511020(+) GGTGCA/GGTGGC 2 -- int10--------
    rs1916346911,2
    --99511021(+) GTGCGA/GTGGCT 2 -- int10--------
    rs1834679541,2
    --99511027(+) TGGCTC/TACGCC 2 -- int10--------
    rs1873458981,2
    --99511062(+) CAAGGC/TGGGCA 2 -- int10--------
    rs1912155891,2
    --99511151(+) TAGCCA/GGGCAT 2 -- int10--------
    rs1821905921,2
    --99511209(+) AAATCA/GCTTGA 2 -- int10--------
    rs1869278491,2
    --99511217(+) TGAACC/TCGGGA 2 -- int10--------
    rs1914935821,2
    C--99511219(+) AACCCA/GGGAGG 2 -- int10--------
    rs1825776151,2
    C--99511251(+) ATCGCA/GCCACT 2 -- int10--------
    rs1484753531,2
    C--99511293(+) ATCTC-/AAAT  
            
    AAATA
    2 -- int10--------
    rs577999771,2
    C--99511320(+) ATAAA-/TAAA/ 
    TAAATAAA
    AATAA
    2 -- int10--------
    rs25719981,2
    C,F,O,H--99511372(-) ACGTAC/TAATTT 2 -- int128Minor allele frequency- T:0.41NS EA NA WA CSA 2772
    rs18654721,2
    C,F,O,A,H--99511563(-) tatagT/Ataagg 2 -- int113Minor allele frequency- A:0.34MN NS EA WA NA CSA 969
    rs1165874781,2
    F--99511623(+) GAGTTC/TTATGA 2 -- int11Minor allele frequency- T:0.08WA 118
    rs1880001761,2
    --99511668(+) GCTGGC/TAGGTG 2 -- int10--------
    rs1397778501,2
    --99511725(+) GCCACC/TGCTAG 2 -- int10--------
    rs1444828021,2
    --99511865(+) AGCCTC/TGAACT 2 -- int10--------
    rs1461962991,2
    --99511866(+) GCCTCA/GAACTC 2 -- int10--------
    rs1390832101,2
    C--99511918(+) TGGGAC/TTACAG 2 -- int10--------
    rs1930339701,2
    --99511945(+) CCAGCC/TAATTT 2 -- int10--------
    rs1498680051,2
    --99512027(+) TCCTGC/TCTCAG 2 -- int10--------
    rs587307471,2
    C,F--99512028(+) CCTGCT/CTCAGC 2 -- int11Minor allele frequency- C:0.00WA 2
    rs1853403231,2
    --99512142(+) CACTGA/GCTTTC 2 -- int10--------
    rs25279091,2
    C,F,H--99512224(-) gcatgA/Cgatgt 2 -- int112Minor allele frequency- C:0.42NA WA CSA EA 374
    rs737116811,2
    C,F--99512268(+) AGAGAC/ACTTCT 2 -- int12Minor allele frequency- A:0.04WA 120
    rs1906368011,2
    C--99512305(+) TCCCCC/TGCCTC 2 -- int10--------
    rs1123465311,2
    F--99512678(+) TCCTCG/ACGTCT 2 -- int11Minor allele frequency- A:0.50CSA 2
    rs1847555301,2
    C--99512746(+) CACTTC/TCTTTT 2 -- int10--------
    rs1880333221,2
    --99512906(+) GTGCCA/GTGCCA 2 -- int10--------
    rs1808427141,2
    --99513127(+) TATTTC/TCCATG 2 -- int10--------
    rs1490519691,2
    --99513232(+) ACCCAC/GGGGCA 2 -- int10--------
    rs1511922871,2
    --99513365(+) GCTCCC/TGAACA 2 -- int10--------
    rs1863359271,2
    --99513408(+) TCCCAC/GTGTAA 2 -- int10--------
    rs1897531171,2
    --99513580(+) ACCTCC/GGGGGC 2 -- int10--------
    rs1818640951,2
    --99513715(+) GGTACA/GTAAGA 2 -- int10--------
    rs1868905521,2
    --99513869(+) ATGTCG/TTTTGC 2 -- int10--------
    rs1909743741,2
    --99513910(+) TCTCTC/TTGTGC 2 -- int10--------
    rs1832677181,2
    --99513943(+) CCTCCG/TAGGAG 2 -- int10--------
    rs1865098731,2
    --99513998(+) GGATTA/CTAAAA 2 -- int10--------
    rs1896700721,2
    --99514014(+) TCTCTA/TGCCTC 2 -- int10--------
    rs1176569341,2
    F--99514097(+) AAGCAT/CGGGAT 2 -- int11Minor allele frequency- C:0.07NA 120
    rs1826187541,2
    C--99514098(+) AGCATA/GGGATC 2 -- int10--------
    rs1882352721,2
    --99514205(+) CAAGAC/TTCCTC 2 -- int10--------
    rs1913800951,2
    C--99514381(+) ATCCAC/G/TGTGGA 4 M L V mis1 int11EU 1307
    rs25719971,2
    C,F,A,H--99514417(-) GATCGG/TTTTTT 2 -- int129Minor allele frequency- T:0.41NS EA NA WA CSA 2776
    rs1835890721,2
    C--99514423(+) CGATCA/GTATCA 2 -- int10--------
    rs1872479301,2
    --99514465(+) CACTGC/TCTGAA 2 -- int10--------
    rs1414706271,2
    --99514506(+) ACAAGA/TTCCTT 2 -- int10--------
    rs1470098391,2
    --99514586(+) GAAGTA/GCTGAG 2 -- int10--------
    rs1142049351,2
    F--99514647(+) GGAATA/TTGCTG 2 -- int11Minor allele frequency- T:0.01WA 118
    rs1383384341,2
    C--99514669(+) TGAAAC/TACCTT 2 -- int10--------
    rs1501852821,2
    --99514700(+) CTTGAA/GGAGCT 2 -- int10------