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Aliases for TRIM39-RPP21 Gene

Aliases for TRIM39-RPP21 Gene

  • TRIM39-RPP21 Readthrough 2 3 5
  • Rpp21 Domain-Containing TRIM Protein 3
  • TRIM39-RPP21 Read-Through Transcript 3
  • TRIM39R 3

External Ids for TRIM39-RPP21 Gene

Previous GeneCards Identifiers for TRIM39-RPP21 Gene

  • GC06U902092
  • GC06P030296
  • GC06P030423
  • GC06P030337
  • GC06P030445

Summaries for TRIM39-RPP21 Gene

Entrez Gene Summary for TRIM39-RPP21 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring TRIM39 (tripartite motif-containing 39) and RPP21 (ribonuclease P/MRP 21kDa subunit) genes on chromosome 6. The read-through transcript encodes a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Nov 2010]

GeneCards Summary for TRIM39-RPP21 Gene

TRIM39-RPP21 (TRIM39-RPP21 Readthrough) is a Protein Coding gene. Among its related pathways are Antigen processing- Ubiquitination and Proteasome degradation and Immune System. An important paralog of this gene is TRIM58.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRIM39-RPP21 Gene

Genomics for TRIM39-RPP21 Gene

Regulatory Elements for TRIM39-RPP21 Gene

Enhancers for TRIM39-RPP21 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around TRIM39-RPP21 on UCSC Golden Path with GeneCards custom track

Genomic Location for TRIM39-RPP21 Gene

Chromosome:
6
Start:
30,328,907 bp from pter
End:
30,346,858 bp from pter
Size:
17,952 bases
Orientation:
Plus strand

Genomic View for TRIM39-RPP21 Gene

Genes around TRIM39-RPP21 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRIM39-RPP21 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRIM39-RPP21 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Proteins for TRIM39-RPP21 Gene

  • Protein details for TRIM39-RPP21 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A096LP39
    Recommended name:
    E3 ubiquitin-protein ligase TRIM39
    Protein Accession:
    A0A096LP39

    Protein attributes for TRIM39-RPP21 Gene

    Size:
    503 amino acids
    Molecular mass:
    57904 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRIM39-RPP21 Gene

Proteomics data for TRIM39-RPP21 Gene at MOPED

Post-translational modifications for TRIM39-RPP21 Gene

No Post-translational modifications

Other Protein References for TRIM39-RPP21 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for TRIM39-RPP21 Gene

Domains & Families for TRIM39-RPP21 Gene

Protein Domains for TRIM39-RPP21 Gene

Suggested Antigen Peptide Sequences for TRIM39-RPP21 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRIM39-RPP21: view

No data available for Gene Families and UniProtKB/Swiss-Prot for TRIM39-RPP21 Gene

Function for TRIM39-RPP21 Gene

Phenotypes for TRIM39-RPP21 Gene

genes like me logo Genes that share phenotypes with TRIM39-RPP21: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRIM39-RPP21 Gene

Localization for TRIM39-RPP21 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TRIM39-RPP21 Gene

Pathways & Interactions for TRIM39-RPP21 Gene

genes like me logo Genes that share pathways with TRIM39-RPP21: view

Interacting Proteins for TRIM39-RPP21 Gene

Gene Ontology (GO) - Biological Process for TRIM39-RPP21 Gene

None

No data available for SIGNOR curated interactions for TRIM39-RPP21 Gene

Drugs & Compounds for TRIM39-RPP21 Gene

No Compound Related Data Available

Transcripts for TRIM39-RPP21 Gene

mRNA/cDNA for TRIM39-RPP21 Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TRIM39-RPP21 Gene

No ASD Table

Relevant External Links for TRIM39-RPP21 Gene

GeneLoc Exon Structure for
TRIM39-RPP21
ECgene alternative splicing isoforms for
TRIM39-RPP21

Expression for TRIM39-RPP21 Gene

mRNA expression in normal human tissues for TRIM39-RPP21 Gene

Integrated Proteomics: protein expression in normal tissues and cell lines from MaxQB for TRIM39-RPP21 Gene



genes like me logo Genes that share expression patterns with TRIM39-RPP21: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for TRIM39-RPP21 Gene

Orthologs for TRIM39-RPP21 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TRIM39-RPP21 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia TRIM39-RPP21 36
  • 95 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 54 (a)
OneToMany
mouse
(Mus musculus)
Mammalia Trim75 36
  • 22 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 40 (a)
OneToMany
Species with no ortholog for TRIM39-RPP21:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TRIM39-RPP21 Gene

ENSEMBL:
Gene Tree for TRIM39-RPP21 (if available)
TreeFam:
Gene Tree for TRIM39-RPP21 (if available)

Paralogs for TRIM39-RPP21 Gene

genes like me logo Genes that share paralogs with TRIM39-RPP21: view

Variants for TRIM39-RPP21 Gene

Structural Variations from Database of Genomic Variants (DGV) for TRIM39-RPP21 Gene

Variant ID Type Subtype PubMed ID
nsv5241 CNV Insertion 18451855

Variation tolerance for TRIM39-RPP21 Gene

Gene Damage Index Score: 12.64; 94.56% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Relevant External Links for TRIM39-RPP21 Gene

Disorders for TRIM39-RPP21 Gene

Relevant External Links for TRIM39-RPP21

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TRIM39-RPP21

No disorders were found for TRIM39-RPP21 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TRIM39-RPP21 Gene

Publications for TRIM39-RPP21 Gene

  1. TRIM39R, but not TRIM39B, regulates type I interferon response. (PMID: 23707810) Kurata R. … Inoko H. (Biochem. Biophys. Res. Commun. 2013) 3 67
  2. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 3
  3. cGMP-dependent protein kinase I interacts with TRIM39R, a novel Rpp21 domain-containing TRIM protein. (PMID: 17601797) Roberts J.D.Jr. … Bloch K.D. (Am. J. Physiol. Lung Cell. Mol. Physiol. 2007) 3

Products for TRIM39-RPP21 Gene

Sources for TRIM39-RPP21 Gene

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