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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TRIM39 Gene

protein-coding   GIFtS: 49
GCID: GC06P030294

tripartite motif containing 39

(Previous names: ring finger protein 23, tripartite motif-containing 39...)
(Previous symbol: RNF23)
 Explore 8 diseases affiliated with
TRIM39 via our new
 Human Malady Compendium 
Biological research products
for TRIM39
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Tripartite Motif Containing 391 2     Testis-Abundant Finger Protein2 3
RNF231 2 3 5     Tripartite Motif-Containing Protein 392 3
RING Finger Protein 231 2 3     TRIM39B2
TFP2 3 5     E3 Ubiquitin-Protein Ligase TRIM392
Tripartite Motif-Containing 391 2     EC 6.3.2.-3

External Ids:    HGNC: 100651   Entrez Gene: 566582   Ensembl: ENSG000002045997   OMIM: 6057005   UniProtKB: Q9HCM93   

Export aliases for TRIM39 gene to outside databases

Previous GC identifers: GC06P030352 GC06P030065 GC06P030401 GC06P030403 GC06P030092


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TRIM39:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three
zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The function of this
protein has not been identified. This gene lies within the major histocompatibility complex class I region on
chromosome 6. Alternate splicing results in two transcript variants encoding different isoforms. (provided by RefSeq,
Jul 2008)

UniProtKB/Swiss-Prot: TRI39_HUMAN, Q9HCM9
Function: E3 ubiquitin-protein ligase. May facilitate apoptosis by inhibiting APC/C-Cdh1-mediated poly-ubiquitination
and subsequent proteasome-mediated degradation of the pro-apoptotic protein MOAP1




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.1  NT_007592.15  NT_113891.2  NT_167244.1  NT_167245.1  NT_167246.1  NT_167248.1  
NT_167249.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TRIM39 gene promoter:
         NRF-2   AML1a   Nkx2-2   Nkx2-5   MRF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTRIM39 promoter sequence
   Search SABiosciences Chromatin IP Primers for TRIM39

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRIM39


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.3   Ensembl cytogenetic band:  6p22.1   HGNC cytogenetic band: 6p22.1

TRIM39 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TRIM39 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P030294:  view genomic region     (about GC identifiers)

Start:
30,294,256 bp from pter      End:
30,311,506 bp from pter
Size:
17,251 bases      Orientation:
plus strand

6 alternative locations:
Chr6+,ALT_REF_LOCI_2 30,284,058-30,340,500      Chr6+,ALT_REF_LOCI_3 30,284,507-30,312,801      Chr6+,ALT_REF_LOCI_6 30,283,753-30,336,591     
Chr6+,ALT_REF_LOCI_1 30,302,488-30,328,044      Chr6+,ALT_REF_LOCI_4 30,262,348-30,279,239      Chr6+,ALT_REF_LOCI_7 30,214,061-30,230,949     

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: TRI39_HUMAN, Q9HCM9 (See protein sequence)
Recommended Name: E3 ubiquitin-protein ligase TRIM39  
Size: 518 amino acids; 59690 Da
Subunit: Interacts with MOAP1
Subcellular location: Cytoplasm, cytosol. Mitochondrion. Note=Found predominantly in the cytosol. Partial shift from
the cytosol to the mitochondria when co-localized with MOAP1
3 PDB 3D structures from and Proteopedia for TRIM39:
2DID (3D)        2DIF (3D)        2ECJ (3D)    
Secondary accessions: Q5STG3 Q5STG4 Q76BL3 Q8IYT9 Q96IB6
Alternative splicing: 2 isoforms:  Q9HCM9-1   Q9HCM9-2   

Explore the universe of human proteins at neXtProt for TRIM39: NX_Q9HCM9

Post-translational modifications:

  • Autoubiquitinated1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9HCM9

  • TRIM39 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_067076.2  NP_742013.1  

    ENSEMBL proteins: 
     ENSP00000405928   ENSP00000394768   ENSP00000379800   ENSP00000406019   ENSP00000379797  
     ENSP00000405498   ENSP00000365847   ENSP00000397952   ENSP00000379796   ENSP00000388224  
     ENSP00000365844   ENSP00000439400  

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    Uscn Proteins for TRIM39

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005622intracellular ----
    GO:0005739mitochondrion IEA--
    GO:0005829cytosol IEA--


    TRIM39 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TRIM39 for domains           About GeneDecksing

    5/11 InterPro domains/families (see all 11):
     IPR006574 PRY
     IPR017907 Znf_RING_CS
     IPR001841 Znf_RING
     IPR001870 B30.2/SPRY
     IPR003877 SPRY_rcpt

    Graphical View of Domain Structure for InterPro Entry Q9HCM9

    ProtoNet protein and cluster: Q9HCM9

    4 Blocks protein families:
    IPB000315 B-box zinc finger signature
    IPB001841 Zn-finger
    IPB003879 Butyrophylin C-terminal DUF signature
    IPB006574 SPRY-associated domain


    UniProtKB/Swiss-Prot: TRI39_HUMAN, Q9HCM9
    Similarity: Belongs to the TRIM/RBCC family
    Similarity: Contains 1 B box-type zinc finger
    Similarity: Contains 1 B30.2/SPRY domain
    Similarity: Contains 1 RING-type zinc finger


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: TRI39_HUMAN, Q9HCM9
    Function: E3 ubiquitin-protein ligase. May facilitate apoptosis by inhibiting APC/C-Cdh1-mediated poly-ubiquitination
    and subsequent proteasome-mediated degradation of the pro-apoptotic protein MOAP1

    Enzyme Number (IUBMB): EC 6.3.2.-1

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TRIM39
    8/33 QIAGEN miScript miRNA Assays for microRNAs that regulate TRIM39 (see all 33):
    hsa-miR-194* hsa-miR-1197 hsa-miR-3921 hsa-miR-548m hsa-miR-124 hsa-miR-3150b-3p hsa-miR-506 hsa-miR-509-3-5p
    SwitchGear 3'UTR luciferase reporter plasmidTRIM39 3' UTR sequence
    Inhib. RNA
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    Gene Ontology (GO): 5 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0005515protein binding IPI--
    GO:0008270zinc ion binding IEA--
    GO:0016874ligase activity IEA--
    GO:0042802identical protein binding IPI--


    TRIM39 for ontologies           About GeneDecksing


    2 GenomeRNAi human phenotypes for TRIM39:
     Increased cell death HMECs cel  Synthetic lethal with Ras 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    UniProtKB/Swiss-Prot: TRI39_HUMAN, Q9HCM9
    Pathway: Protein modification; protein ubiquitination

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TRIM39

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    5/34 Interacting proteins for TRIM39 (Q9HCM91, 2, 3 ENSP000003658444) via UniProtKB, MINT, STRING, and/or I2D (see all 34)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    TRIM17Q9Y5771, 2, 3, ENSP000003477944EBI-739510,EBI-743894 MINT-66402 I2D: score=5 STRING: ENSP00000347794
    DCUN1D1Q96GG92, 3, ENSP000002927824MINT-66918 I2D: score=5 STRING: ENSP00000292782
    PLCD4Q9BRC72, 3, ENSP000003886314MINT-67359 I2D: score=5 STRING: ENSP00000388631
    UBE2D3P610772, 3, ENSP000003497224MINT-67915 I2D: score=5 STRING: ENSP00000349722
    UBTD1Q9HAC82, 3MINT-66738 I2D: score=4 
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006915apoptotic process IEA--
    GO:0008150biological_process ND--
    GO:0016567protein ubiquitination IEA--


    TRIM39 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TRIM39
    Search CenterWatch for drugs/clinical trials and news about TRIM39 / TRI39 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for TRIM39 gene (2 alternative transcripts): 
    NM_021253.3  NM_172016.2  

    Unigene Cluster for TRIM39:

    Tripartite motif containing 39
    Hs.413493  [show with all ESTs]
    Unigene Representative Sequence: NM_172016
    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000458516 ENST00000440271 ENST00000396551(uc003npz.3) ENST00000428728
    ENST00000396548 ENST00000428404 ENST00000376659(uc003nqb.3 uc003nqc.3)
    ENST00000428555 ENST00000396547 ENST00000420746 ENST00000376656(uc010jrz.3)
    ENST00000540416

    miRNA
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    8/33 QIAGEN miScript miRNA Assays for microRNAs that regulate TRIM39 (see all 33):
    hsa-miR-194* hsa-miR-1197 hsa-miR-3921 hsa-miR-548m hsa-miR-124 hsa-miR-3150b-3p hsa-miR-506 hsa-miR-509-3-5p
    SwitchGear 3'UTR luciferase reporter plasmidTRIM39 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TRIM39 (see all 7)
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    Additional cDNA sequence: 

    AB046381.1 AK292512.1 BC007661.2 BC034985.1 BT007370.1 

    13 DOTS entries:

    DT.211152  DT.86846484  DT.97858723  DT.100814392  DT.100814396  DT.92423789  DT.97858724  DT.315448 
    DT.121346123  DT.75102321  DT.75125593  DT.100814391  DT.121345655 

    7 AceView cDNA sequences:

    NM_021253 NM_172016 BC034985 AX776007 AB046381 BT007370 BC007661 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TRIM39 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CCAAACCAAA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See TRIM39 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TRIM39

    SOURCE GeneReport for Unigene cluster: Hs.413493

    UniProtKB/Swiss-Prot: TRI39_HUMAN, Q9HCM9
    Tissue specificity: Ubiquitous; highly expressed in brain, heart, kidney, liver, skeletal muscle, spleen and testis

        SABiosciences Expression via Pathway-Focused PCR Array including TRIM39: 
              Ubiquitin Ligases in human mouse rat

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIM39

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for TRIM39 gene from 3/8 species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves TRIM391 tripartite motif-containing 39 53.63(n)
    42.47(a)
      417041  NM_001006196.2  NP_001006196.2 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    70(a)
    1 → many
    2(192582206-192597320)
    zebrafish
    (Danio rerio)
    Actinopterygii trim476
    tripartite motif containing 47
    26(a)
    possible ortholog
    10(26752552-26762609)


    ENSEMBL Gene Tree for TRIM39 (if available)
    TreeFam Gene Tree for TRIM39 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TRIM39 gene
    TRIM42  TRIM72  TRIM262  TRIM342  TRIML12  TRIM272  TRIM582  TRIM682  
    TRIM102  TRIM152  TRIM602  TRIM222  TRIM172  TRIM52  TRIM62  TRIM6-TRIM342  
    TRIM212  TRIM382  TRIM39-RPP212  TRIM112  
    18/92 SIMAP similar genes for TRIM39 using alignment to 13 protein entries:     TRI39_HUMAN (see all proteins) (see all similar genes):
    TRIM39R    RPP21    ERMAP    FLJ00123    TRIM61    TRIM60
    RNF112    TRIM41    TRIM27    BT3.3    TRIM73    MEFV
    TRIM5    TRIM75    PCGF3    RNF151    TRIM46    TRIM17

    TRIM39 for paralogs           About GeneDecksing


    3 Pseudogenes.org Pseudogenes for TRIM39
    PGOHUM00000244510 PGOHUM00000246132 PGOHUM00000243134


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/282 NCBI SNPs in TRIM39 are shown (see all 282    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs92786471,2
    C--30099261(+) TTTTT-/TAGACG 1 -- int10--------
    rs283600251,2
    C--30292633(+) TTTGTA/CTCTAC 4 -- int1 us2k10--------
    rs283600261,2
    C--30292635(+) TGTCTC/TTACTA 4 -- us2k1 int10--------
    rs1424718621,2
    --30292940(+) CCTTTC/TTTCCT 3 -- us2k1 int10--------
    rs1913454401,2
    --30293025(+) CTCCTA/CTTGTT 4 -- us2k1 int10--------
    rs171948241,2
    C,F,H,--30293186(+) AGTTAG/ATGGCT 5 -- us2k1 int118Minor allele frequency- A:0.11MN NS EA WA CSA NA 2432
    rs1148371911,2
    --30293228(+) TGAATT/CAGAAC 4 -- int1 us2k11Minor allele frequency- C:0.01WA 118
    rs1821669721,2
    --30293374(+) ATGTGC/TGATCC 4 -- us2k1 int10--------
    rs12645831,2
    C,F,A,H,--30293483(-) ATTGTG/ACTGCT 5 -- int1 us2k117Minor allele frequency- A:0.04EA NA NS MN 1796
    rs171884841,2
    C,F,--30293585(+) GCGGCG/TGGGAG 5 -- int1 us2k15Minor allele frequency- T:0.07MN WA NA EA 446

    HapMap Linkage Disequilibrium report for TRIM39 (30294256 - 30311506 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for TRIM39: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TRIM39
    DNA2.0 Custom Variant and Variant Library Synthesis for TRIM39

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TRIM39 for disorders           About GeneDecksing

    OMIM gene information: 605700    OMIM disorders: --

    8 diseases for TRIM39:    About MalaCards
    acute monocytic leukemia    systemic lupus erythematosus    tularemia    lupus erythematosus
    gonorrhea    monocytic leukemia    behcet's disease    leukemia

    3 diseases from the University of Copenhagen DISEASES database for TRIM39:
    Gonorrhea     Dissociative disorder     Tularemia
    Human Genome Epidemiology (HuGE) Navigator: TRIM39 (2 documents)

    Export disorders for TRIM39 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TRIM39 gene, integrated from 9 sources (see all 21):
    (articles sorted by number of sources associating them with TRIM39)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning of testis-abundant finger protein/ring finger protein 23 (RNF23), a novel RING-B box-coiled coil-B30.2 protein on the class I region of the human MHC. (PubMed id 11006080)1, 2, 3, 9 Orimo A.... Muramatsu M. (2000)
    2. The Trim39 ubiquitin ligase inhibits APC/CCdh1-mediated degradation of the Bax activator MOAP-1. (PubMed id 22529100)1, 2 Huang N.J.... Kornbluth S. (2012)
    3. TRIM39 is a MOAP-1-binding protein that stabilizes MOAP-1 through inhibition of its poly-ubiquitination process. (PubMed id 19100260)1, 2 Lee S.S....Yu V.C. (2009)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Systematic analysis of dimeric E3-RING interactions re veals increased combinatorial complexity in human ubiquitination networks. (PubMed id 22493164)1 Woodsmith J....Sanderson C.M. (2012)
    6. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    7. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
    8. TRIM39 and RNF39 are associated with BehAset's disease independently of HLA-Ba8951 and -Aa8926. (PubMed id 20875797)1 Kurata R....Inoko H. (2010)
    9. Analysis of the human E2 ubiquitin conjugating enzyme protein interaction network. (PubMed id 19549727)1 Markson G....Sanderson C.M. (2009)
    10. High-density SNP screening of the major histocompatib ility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PubMed id 19851445)1 Barcellos L.F....Criswell L.A. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 56658 HGNC: 10065 AceView: TRIM39 Ensembl:ENSG00000204599 euGenes: HUgn56658
    ECgene: TRIM39 H-InvDB: TRIM39

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TRIM39 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for TRIM39 gene:
    Search GeneIP for patents involving TRIM39

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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