Aliases for TRIM38 Gene
External Ids for TRIM38 Gene
Previous HGNC Symbols for TRIM38 Gene
Previous GeneCards Identifiers for TRIM38 Gene
This gene encodes a member of the tripartite motif (TRIM) family. The encoded protein contains a RING-type zinc finger, B box-type zinc finger and SPRY domain. The function of this protein has not been identified. A pseudogene of this gene is located on the long arm of chromosome 4. [provided by RefSeq, Jul 2012]
GeneCards Summary for TRIM38 Gene
TRIM38 (Tripartite Motif Containing 38) is a Protein Coding gene. Among its related pathways are Interleukin-3, 5 and GM-CSF signaling and Immune System. GO annotations related to this gene include ligase activity and signal transducer activity. An important paralog of this gene is TRIM58.
UniProtKB/Swiss-Prot for TRIM38 Gene
E3 ubiquitin-protein ligase. Mediates Lys-48-linked polyubiquitination and proteasomal degradation of the critical TLR adapter TICAM1, inhibiting TLR3-mediated type I interferon signaling.