TRIM37 Gene
protein-coding GIFtS: 62
GCID: GC17M057059
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|
tripartite motif containing 37(Previous name: tripartite motif-containing 37 ) (Previous symbol: MUL)
| |
Aliases for TRIM37 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Tripartite Motif Containing 371 2 | | Tripartite Motif-Containing Protein 372 3 | | MUL1 2 3 5 | | Tripartite Motif-Containing 371 | | POB11 2 3 | | E3 Ubiquitin-Protein Ligase TRIM372 | | KIAA08981 3 5 | | RING-B-Box-Coiled-Coil Protein2 | | TEF31 2 | | EC 6.3.2.-3 | | Mulibrey Nanism Protein2 3 | | |
Export aliases for TRIM37 gene to outside databasesPrevious GC identifers: GC17M056903 GC17M059637 GC17M057401 GC17M057549 GC17M054430 GC17M054414 GC17M052420 |
Summaries for TRIM37 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for TRIM37: This gene encodes a member of the tripartite motif (TRIM) family, whose members are involved in diverse cellularfunctions such as developmental patterning and oncogenesis. The TRIM motif includes zinc-binding domains, a RINGfinger region, a B-box motif and a coiled-coil domain. The RING finger and B-box domains chelate zinc and might beinvolved in protein-protein and/or protein-nucleic acid interactions. The gene mutations are associated with mulibrey(muscle-liver-brain-eye) nanism, an autosomal recessive disorder that involves several tissues of mesodermal origin.Alternatively spliced transcript variants encoding the same protein have been identified. (provided by RefSeq, Jul2008) UniProtKB/Swiss-Prot: TRI37_HUMAN, O94972Function: E3 ubiquitin-protein ligase Gene Wiki entry for TRIM37
|
Genomic Views for TRIM37 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010783.15
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the TRIM37 gene promoter: Tal-1 p53 SREBP-1c CUTL1 E47 SREBP-1b SREBP-1a Cart-1 ATF6 Other transcription factors
Search SABiosciences Chromatin IP Primers for TRIM37
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRIM37 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q23.2 Ensembl cytogenetic band: 17q22 HGNC cytogenetic band: 17qTRIM37 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17M057059: view genomic region
(about GC identifiers)
Start:
|
57,059,999 bp from pter |
End:
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57,184,282 bp from pter |
Size:
|
124,284 bases |
Orientation:
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minus strand |
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Proteins for TRIM37 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: TRI37_HUMAN, O94972 (See
protein sequence)Recommended Name: E3 ubiquitin-protein ligase TRIM37 Size: 964 amino acids; 107906 Da
Subcellular location: Cytoplasm, perinuclear region. Peroxisome. Note=Found in vesicles of the peroxisome. Aggregatesas aggresomes, a perinuclear region where certain misfolded or aggregated proteins are sequestered for proteasomaldegradation
Sequence caution: Sequence=BAA74921.1; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for TRIM37:3LRQ (3D)
 
Secondary accessions: Q7Z3E6 Q8IYF7 Q8WYF7Alternative splicing: 2 isoforms: O94972-1 O94972-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for TRIM37: NX_O94972
Post-translational modifications:
Auto-ubiquitinated1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O94972 TRIM37 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001005207.1 NP_056109.1 ENSEMBL proteins: ENSP00000464666 ENSP00000462778 ENSP00000376785 ENSP00000462340 ENSP00000262294 ENSP00000376784 ENSP00000462863 ENSP00000464590 ENSP00000464688 ENSP00000464263 ENSP00000365319 Reactome Protein details: O94972 Human Recombinant Protein Products:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
TRIM37 for ontologies About GeneDecksing
TRIM37 Antibody Products: Assay Products for TRIM37: |
Protein
Domains / Families for TRIM37 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
TRIM37 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry O94972ProtoNet protein and cluster: O94972 4 Blocks protein families: IPB000315 B-box zinc finger signature IPB001841 Zn-finger IPB002083 Meprin/TRAF-like MATH IPB003649 B-box
UniProtKB/Swiss-Prot: TRI37_HUMAN, O94972Similarity: Belongs to the TRIM/RBCC familySimilarity: Contains 1 B box-type zinc fingerSimilarity: Contains 1 MATH domainSimilarity: Contains 1 RING-type zinc finger |
Function for TRIM37 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: TRI37_HUMAN, O94972Function: E3 ubiquitin-protein ligaseEnzyme Number (IUBMB): EC 6.3.2.-1
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TRIM37 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TRIM37 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): TRIM37 (NM_015294) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TRIM37 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRIM37  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIM37 |
Gene Ontology (GO): 5/6 molecular function terms (GO ID links to tree view) (see all 6): About this table
TRIM37 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for TRIM37:
|
Pathways & Interactions for TRIM37 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Antigen processing: Ubiquitination & Proteasome degradation | | | 2 | Immune System | |
Pathway sources See GeneCards unified pathways Show all pathways
5
Reactome Pathways for TRIM37
1
Kegg Pathway (Kegg details for TRIM37): UniProtKB/Swiss-Prot: TRI37_HUMAN, O94972Pathway: Protein modification; protein ubiquitination
TRIM37 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TRIM37
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/58 Interacting proteins for TRIM37 (O949721, 2, 3 ENSP000002622944) via UniProtKB, MINT, STRING, and/or I2D (see all 58)
| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| PRC1 | O436631, 2, 3, ENSP000003777934 | EBI-741602,EBI-741137 MINT-67438 I2D:
score=6 STRING: ENSP00000377793 | | APTX | Q7Z2E32, 3, ENSP000004008064 | MINT-2860941 MINT-2860960 I2D:
score=3 STRING: ENSP00000400806 | | APEX2 | Q9UBZ42, 3, ENSP000003641264 | MINT-66277 I2D:
score=5 STRING: ENSP00000364126 | | BYSL | Q138952, 3, ENSP000002303404 | MINT-66930 I2D:
score=5 STRING: ENSP00000230340 | | FAM107A | O959902, 3, ENSP000003542704 | MINT-66452 I2D:
score=5 STRING: ENSP00000354270 | About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table
TRIM37 for ontologies About GeneDecksing
|
Drugs & Compounds for TRIM37 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for TRIM37 Search CenterWatch for drugs/clinical trials and news about TRIM37 / TRI37 
|
Transcripts for TRIM37 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for TRIM37 gene (2 alternative transcripts): NM_001005207.2 NM_015294.3 Unigene Cluster for TRIM37: Tripartite motif containing 37 Hs.579079 [show with all ESTs]Unigene Representative Sequence: NM_01529414 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000585287 ENST00000583945 ENST00000393066(uc002iwy.4) ENST00000577554 ENST00000262294 ENST00000393065 ENST00000581468 ENST00000582852 ENST00000580973 ENST00000580122 ENST00000580620 ENST00000583387 ENST00000584889 ENST00000376149(uc002iwz.4 uc002ixa.4 uc010woc.2)
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TRIM37 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TRIM37 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): TRIM37 (NM_015294) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for TRIM37 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRIM37  |
Additional cDNA sequence: AB020705.1 AF213365.1 AK022701.1 AK025648.1 AK289674.1 AK292459.1 AK294850.1 BC036012.1 BX537955.1 18 DOTS entries: DT.456338 DT.97843497 DT.91723801 DT.314049 DT.95252077 DT.120930631 DT.100693863 DT.100794522 DT.86846390 DT.91723787 DT.97843499 DT.120930369 DT.120930495 DT.91723786 DT.91723788 DT.91723799 DT.314344 DT.75106535 24/145 AceView cDNA sequences (see all 145): AI339566 AI885776 AI699757 BQ229921 AK025648 AL560678 BQ278933 BM471820 BG681041 BU501053 BX492275 CB163050 AI080375 CR606792 BF511737 AA411819 BI827062 AW118387 BP361937 BM083580 AA099340 BX537955 AU125638 NM_001005207 GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for TRIM37 (see all 9) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19a | · | |
| SP1: | |   | |   | |   | |   | |   | |   | - |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | - |   | |   | - |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 19b | ^ | 20a | · | 20b | ^ | 21 | ^ | 22 | ^ | 23 | ^ | 24 | ^ | 25 | ^ | 26a | · | 26b | |
| SP1: | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for TRIM37
|
Expression for TRIM37 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| TRIM37 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: TGAGAGACAT
About this image See TRIM37 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for TRIM37
SOURCE GeneReport for Unigene cluster: Hs.579079 UniProtKB/Swiss-Prot: TRI37_HUMAN, O94972Tissue specificity: Ubiquitous SABiosciences Expression via Pathway-Focused PCR Array including TRIM37:
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TRIM37 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TRIM37 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRIM37 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRIM37 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIM37 |
Orthologs for TRIM37 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for TRIM37 gene from 6/20 species (see all 20) About this table
ENSEMBL Gene Tree for TRIM37 (if available) TreeFam Gene Tree for TRIM37 (if available)  |
Paralogs for TRIM37 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| -- |
Genomic Variants for TRIM37 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 17 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for TRIM37 (57059999 - 57184282 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 3 variations for TRIM37 3 CNVs: 4043 32188 37508 Human Gene Mutation Database (HGMD): TRIM37
 | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TRIM37 |
|
Disorders
/ Diseases for TRIM37 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
TRIM37 for disorders About GeneDecksing
OMIM gene information: 605073 OMIM disorders: 253250 UniProtKB/Swiss-Prot: TRI37_HUMAN, O94972
Defects in TRIM37 are the cause of mulibrey nanism (MUL) [MIM:253250]; also known as muscle-liver-brain-eyenanism. MUL is an autosomal recessive disorder that involves several tissues of mesodermal origin, implying a defectin a highly pleiotropic gene. Characteristic features include severe growth failure of prenatal onset and constrictivepericardium with consequent hepatomegaly. In addition, muscle hypotonia, J-shaped sella turcica, yellowish dots in theocular fundi, typical dysmorphic features and hypoplasia of various endocrine glands causing hormonal deficiency arecommon 10 diseases for TRIM37: About MalaCardsmulibrey nanism human immunodeficiency virus infectious disease growth disorders insulin resistance wilms tumor neutropenia hypotonia ataxia immunodeficiency malaria 3 diseases from the University of Copenhagen DISEASES database for TRIM37:Mulibrey nanism Malaria Human immunodeficiency virus infectious disease 8 Novoseek disease relationships for TRIM37 gene About this table
Export disorders for TRIM37 gene to outside databases
|
Publications for TRIM37 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for TRIM37 gene, integrated from 9 sources (see all 34): (articles sorted by number of sources associating them with TRIM37) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Gene encoding a new RING-B-box-coiled-coil protein is mutated in mulibrey nanism. (PubMed id 10888877)1, 2, 3 Avela K.... Lehesjoki A.E. (2000)
- The TRIM37 gene encodes a peroxisomal RING-B-box-coiled-coil protein: classification of mulibrey nanism as a new peroxisomal disorder. (PubMed id 11938494)1, 2, 9 Kallijarvi J....Lehesjoki A.E. (2002)
- Novel mutations in the TRIM37 gene in Mulibrey Nanism. (PubMed id 15108285)1, 2, 9 Hamalainen R.H....Lehesjoki A.E. (2004)
- Wilms' tumor and novel TRIM37 mutations in an Australian patient with mulibrey nanism. (PubMed id 17100991)1, 2, 9 Haemaelaeinen R.H.... Lehesjoki A.-E. (2006)
- A novel splice site mutation in the TRIM37 gene causes mulibrey nanism in a Turkish family with phenotypic heterogeneity. (PubMed id 12754710)1, 2, 9 Jagiello P.... Gencik M. (2003)
- TRIM37 defective in mulibrey nanism is a novel RING finger ubiquitin E3 ligase. (PubMed id 15885686)1, 2 Kallijarvi J....Lehesjoki A.E. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10048485)1, 2 Nagase T....Ohara O. (1998)
- Assignment of the mulibrey nanism gene to 17q by linkage and linkage-disequilibrium analysis. (PubMed id 9106536)1, 3 Avela K....Lehesjoki A.E. (1997)
- Gynecological tumors in Mulibrey nanism and role for RING finger protein TRIM37 in the pathogenesis of ovarian fibrothecomas. (PubMed id 19329943)1, 9 Karlberg S....Butzow R. (2009)
|
External Searches for TRIM37 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing TRIM37 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing TRIM37 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing TRIM37 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
|
About This Section
| Patent Information for TRIM37 gene: Search GeneIP for patents involving TRIM37
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for TRIM37 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
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| | | | OriGene Antibodies for TRIM37 | | OriGene shRNA RFP for TRIM37 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TRIM37 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TRIM37 | | OriGene Protein Over-expression Lysate for TRIM37 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for TRIM37 | | OriGene 3'-UTR Clone for TRIM37 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TRIM37 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TRIM37 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for TRIM37 | | OriGene Custom Protein Services for TRIM37 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TRIM37 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TRIM37 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRIM37 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TRIM37 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRIM37 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRIM37 |
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| | | Search Tocris compounds for TRIM37 |
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 | | TRIM37 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIM37 |
|  |  |  | | | ThermoFisher Antibody for TRIM37 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRIM37 |
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