Aliases for TRIM36 Gene
External Ids for TRIM36 Gene
Previous GeneCards Identifiers for TRIM36 Gene
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for TRIM36 Gene
TRIM36 (Tripartite Motif Containing 36) is a Protein Coding gene. Diseases associated with TRIM36 include Anencephaly. Among its related pathways are Innate Immune System and Class I MHC mediated antigen processing and presentation. GO annotations related to this gene include ligase activity and ubiquitin-protein transferase activity. An important paralog of this gene is TRIM46.
UniProtKB/Swiss-Prot for TRIM36 Gene
E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. Involved in chromosome segregation and cell cycle regulation. May play a role in the acrosome reaction and fertilization.