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TRIM31 Gene

protein-coding   GIFtS: 50
GCID: GC06M030129

Tripartite Motif Containing 31

(Previous name: tripartite motif-containing 31)
  See TRIM31-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Tripartite Motif Containing 311 2     HCG12
Tripartite Motif-Containing Protein 312 3     E3 Ubiquitin-Protein Ligase TRIM312
C6orf132 3     Ring Finger Protein2
RNF2 3     Tripartite Motif-Containing 31 Gamma2
HCGI2 5     EC 6.3.2.-3
Tripartite Motif-Containing 311     

External Ids:    HGNC: 162891   Entrez Gene: 110742   Ensembl: ENSG000002046167   OMIM: 6093165   UniProtKB: Q9BZY93   

Export aliases for TRIM31 gene to outside databases

Previous GC identifers: GC06M030155 GC06M029841 GC06M030176 GC06M030178 GC06M030073 GC06M029887


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for TRIM31 Gene:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three
zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes
to both the cytoplasm and the nucleus. Its function has not been identified. (provided by RefSeq, Jul 2008)

GeneCards Summary for TRIM31 Gene:
TRIM31 (tripartite motif containing 31) is a protein-coding gene. Diseases associated with TRIM31 include lymphocytic choriomeningitis. GO annotations related to this gene include ligase activity. An important paralog of this gene is TRIM50.

UniProtKB/Swiss-Prot: TRI31_HUMAN, Q9BZY9
Function: Regulator of Src-induced anchorage independent cell growth (By similarity). May have E3
ubiquitin-protein ligase activity

Gene Wiki entry for TRIM31 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000006.11  NT_007592.16  NT_113891.3  NT_167245.2  NT_167246.2  NT_167247.2  NT_167248.2  NT_167249.2  
NC_018917.2  NT_167244.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TRIM31 gene promoter:
         GATA-3   AML1a   RelA   NF-kappaB   GATA-2   PPAR-gamma1   PPAR-gamma2   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTRIM31 promoter sequence
   Search Chromatin IP Primers for TRIM31

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TRIM31


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.3   Ensembl cytogenetic band:  6p22.1   HGNC cytogenetic band: 6p21.3

TRIM31 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TRIM31 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M030129:  view genomic region     (about GC identifiers)

Start:
30,070,674 bp from pter      End:
30,080,883 bp from pter
Size:
10,210 bases      Orientation:
minus strand

Selected alternative locations (see all 7):
Chr6-,NT_167249 1,401,127-1,411,311      Chr6-,NT_167248 1,363,640-1,373,827      Chr6-,NT_113891.2 1,582,796-1,592,995     
Chr6-,NT_167245 1,364,399-1,374,585      Chr6-,NT_167247 1,452,557-1,462,748      Chr6-,NT_167246 1,369,234-1,379,420     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TRI31_HUMAN, Q9BZY9 (See protein sequence)
Recommended Name: E3 ubiquitin-protein ligase TRIM31  
Size: 425 amino acids; 48244 Da
Subunit: Interacts with isoform p52shc of SHC1 (By similarity). May form oligomers
Sequence caution: Sequence=AAH16866.1; Type=Erroneous initiation;
2 PDB 3D structures from and Proteopedia for TRIM31:
2YSJ (3D)        2YSL (3D)    
Secondary accessions: A6NLX6 A9R9Q4 Q53H52 Q5RI37 Q5SRJ7 Q5SRJ8 Q5SS28 Q96AK4 Q96AP8 Q99579
Q9BZY8
Alternative splicing: 2 isoforms:  Q9BZY9-1   Q9BZY9-2   (May be produced at very low levels due to a premature stop codon in the mRNA, leading to nonsense-mediated mRNA decay)

Explore the universe of human proteins at neXtProt for TRIM31: NX_Q9BZY9

Explore proteomics data for TRIM31 at MOPED

Post-translational modifications: 

  • Auto-ubiquitinated (in vitro)1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TRIM31 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_008959.3  
    ENSEMBL proteins: 
     ENSP00000365924   ENSP00000444311  

    TRIM31 Human Recombinant Protein Products:

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    LSBio Antibodies in human, mouse, rat for TRIM31

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    Search eBioscience for ELISAs for TRIM31 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    TRIM: Tripartite motif containing / Tripartite motif containing
    RNF: RING-type (C3HC4) zinc fingers

    5 InterPro protein domains:
     IPR017907 Znf_RING_CS
     IPR001841 Znf_RING
     IPR020457 Znf_B-box_chordata
     IPR000315 Znf_B-box
     IPR013083 Znf_RING/FYVE/PHD

    Graphical View of Domain Structure for InterPro Entry Q9BZY9

    ProtoNet protein and cluster: Q9BZY9

    2 Blocks protein domains:
    IPB000315 B-box zinc finger signature
    IPB001841 Zn-finger


    UniProtKB/Swiss-Prot: TRI31_HUMAN, Q9BZY9
    Similarity: Belongs to the TRIM/RBCC family
    Similarity: Contains 1 B box-type zinc finger
    Similarity: Contains 1 RING-type zinc finger


    Find genes that share domains with TRIM31           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TRI31_HUMAN, Q9BZY9
    Function: Regulator of Src-induced anchorage independent cell growth (By similarity). May have E3
    ubiquitin-protein ligase activity

         Enzyme Number (IUBMB): EC 6.3.2.-1

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--
    GO:0016874ligase activity IEA--
    GO:0046872metal ion binding ----
         
    Find genes that share ontologies with TRIM31           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TRIM31
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    hsa-miR-623
    SwitchGear 3'UTR luciferase reporter plasmidTRIM31 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TRIM31

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    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRIM31

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TRI31_HUMAN, Q9BZY9: Cytoplasm. Mitochondrion. Note=Predominantly expressed in the cytoplasm but a fraction is
    associated with the mitochondria
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion5
    nucleus3
    cytosol2

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005739mitochondrion IEA--

    Find genes that share ontologies with TRIM31           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    UniProtKB/Swiss-Prot: TRI31_HUMAN, Q9BZY9
    Pathway: Protein modification; protein ubiquitination

        Pathway & Disease-focused RT2 Profiler PCR Array including TRIM31: 

              Ubiquitin Ligases in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for TRIM31

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    Selected Interacting proteins for TRIM31 (Q9BZY93 ENSP000003659244) via UniProtKB, MINT, STRING, and/or I2D (see all 14)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TRIM23P364063, ENSP000002315244I2D: score=2 STRING: ENSP00000231524
    MAGEA1P433553, ENSP000003490854I2D: score=4 STRING: ENSP00000349085
    TRAF2Q129333, ENSP000002476684I2D: score=4 STRING: ENSP00000247668
    UBE2D1P516683I2D: score=2 
    UBE2D2P628373I2D: score=2 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016567protein ubiquitination IEA--
    GO:0032897negative regulation of viral transcription IDA18248090
    GO:0045087innate immune response IMP18248090
    GO:0046597negative regulation of viral entry into host cell IMP18248090
    GO:0051091positive regulation of sequence-specific DNA binding transcription factor activity IMP--

    Find genes that share ontologies with TRIM31           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TRIM31 (TRI31)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TRIM31 gene (2 alternative transcripts): 
    NM_007028.3  NM_052816.2  

    Unigene Cluster for TRIM31:

    Tripartite motif containing 31
    Hs.493275  [show with all ESTs]
    Unigene Representative Sequence: NM_007028
    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000471695 ENST00000376734(uc003npg.1 uc003npi.3) ENST00000468264
    ENST00000484583 ENST00000485864 ENST00000480808 ENST00000493404 ENST00000540829

    miRNA
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    1 qRT-PCR Assays for microRNA that regulate TRIM31:
    hsa-miR-623
    SwitchGear 3'UTR luciferase reporter plasmidTRIM31 3' UTR sequence
    Inhib. RNA
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    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TRIM31
      QuantiTect SYBR Green Assays in human, mouse, rat TRIM31
      QuantiFast Probe-based Assays in human, mouse, rat TRIM31

    Additional mRNA sequence: 

    AB303153.1 AF230386.1 AK222729.1 AK290270.1 BC016866.1 BC017017.1 BT006675.1 X81006.1 
    Y07828.1 

    9 DOTS entries:

    DT.440910  DT.100774827  DT.86847856  DT.100713805  DT.95345060  DT.99938506  DT.100774825  DT.97771307 
    DT.86838603 

    Selected AceView cDNA sequences (see all 58):

    CB305715 AI394072 AK057215 AW062605 BM847963 BC045588 BI461959 AI733722 
    CB156085 BI765211 BT006675 BM982376 BG287658 AI492185 NM_052816 AF230386 
    AW206410 AI732398 BM792549 BE049219 BC017017 BM797769 BG328177 NM_007028 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TRIM31 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGCCCGACCA
    TRIM31 Expression
    About this image


    TRIM31 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Gut Tube (Gastrointestinal Tract)    fully expand to see all 2 entries
             Hindgut
     
     Colon (Gastrointestinal Tract)
    TRIM31 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TRIM31 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.493275

    UniProtKB/Swiss-Prot: TRI31_HUMAN, Q9BZY9
    Tissue specificity: Up-regulated in gastric adenocarcinomas

        Pathway & Disease-focused RT2 Profiler PCR Array including TRIM31: 
              Ubiquitin Ligases in human mouse rat

    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIM31

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of human and mouse.

    Orthologs for TRIM31 gene from Selected species (see all 4)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Trim311 , 5 tripartite motif-containing 311, 5 70.04(n)1
    54.6(a)1
      17 (19.16 cM)5
    2247621  NM_146077.21  NP_666189.11 
     368981185 


    ENSEMBL Gene Tree for TRIM31 (if available)
    TreeFam Gene Tree for TRIM31 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TRIM31 gene
    TRIM502  TRIM102  TRIM732  TRIM692  TRIM152  TRIM262  TRIM742  TRIM352  
    TRIM522  TRIM622  TRIM412  TRIM722  
    11 SIMAP similar genes for TRIM31 using alignment to 3 protein entries:     TRI31_HUMAN (see all proteins):
    TRIM41    BRCA1    TRIM22    TRIM5    TRIM39    TRIM68
    TRIM26    DKFZp686F23130    BMI1    TRIM61    TRIM17

    Find genes that share paralogs with TRIM31           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TRIM31 (see all 364)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs92785801,2
    C--29878935(+) ATAAA-/AAA   
      G
    /GAAA
    AATGA
    1 -- int10--------
    rs20721101,2
    C,F,H--30070178(-) CACACA/GGCCCC 1 -- ds500112Minor allele frequency- G:0.21EA NA WA 2228
    rs1493558111,2
    C--30070192(+) ATGAGG/TAGAAA 1 -- ds50010--------
    rs1447132701,2
    C--30070241(+) ACCTTC/TCTCTG 1 -- ds50010--------
    rs20721091,2
    C,F,H--30070275(-) GCATCG/CAGCGG 1 -- ds500112Minor allele frequency- C:0.14EA NS NA 2740
    rs25239941,2
    C,F,A,H--30070346(-) GGCGGT/GGCCGG 1 -- ds50019Minor allele frequency- G:0.30NA WA EA 370
    rs574653941,2
    C--30070372(+) TTAATC/TCCTAA 1 -- ds50010--------
    rs1926068091,2
    --30070373(+) TAATCC/TCTAAA 1 -- ds50010--------
    rs1419444371,2
    --30070441(+) GAGATC/GATTTC 1 -- ds50010--------
    rs1832160871,2
    --30070505(+) TCCCAC/TGTCTA 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for TRIM31 (30070674 - 30080883 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for TRIM31:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2731777CNV Deletion23290073
    nsv884055CNV Loss21882294
    dgv6518n71CNV Gain21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TRIM31
    DNA2.0 Custom Variant and Variant Library Synthesis for TRIM31

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609316    OMIM disorders: --

    1 disease for TRIM31:    
    About MalaCards
    lymphocytic choriomeningitis


    Find genes that share disorders with TRIM31           About GenesLikeMe

    Genetic Association Database (GAD): TRIM31
    Human Genome Epidemiology (HuGE) Navigator: TRIM31 (4 documents)

    Export disorders for TRIM31 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TRIM31 gene, integrated from 10 sources (see all 34):
    (articles sorted by number of sources associating them with TRIM31)
        Utopia: connect your pdf to the dynamic
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    1. The tripartite motif family identifies cell compartments. (PubMed id 11331580)1, 2, 3 Reymond A.... Ballabio A. (EMBO J. 2001)
    2. High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PubMed id 19851445)1, 4 Barcellos L.F....Criswell L.A. (PLoS Genet. 2009)
    3. An unappreciated role for RNA surveillance. (PubMed id 14759258)1, 2 Hillman R.T.... Brenner S.E. (Genome Biol. 2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (Nature 2003)
    6. Genome-wide association study identified the human leukocyte antigen region as a novel locus for plasma beta-2 microglobulin. (PubMed id 23417110)1 Tin A....Kao W.H. (Hum. Genet. 2013)
    7. Direct and indirect control of mitogen-activated protein kinase pathway-associated components, BRAP/IMP E3 ubiquitin ligase and CRAF/RAF1 kinase, by the deubiquitylating enzyme USP15. (PubMed id 23105109)1 Hayes S.D....UrbAc S. (J. Biol. Chem. 2012)
    8. Systematic analysis of dimeric E3-RING interactions reveals increased combinatorial complexity in human ubiquitination networks. (PubMed id 22493164)1 Woodsmith J....Sanderson C.M. (amp 2012)
    9. Functional interactions between ubiquitin E2 enzymes and TRIM proteins. (PubMed id 21143188)1 Napolitano L.M....Meroni G. (Biochem. J. 2011)
    10. The cellular level of TRIM31, an RBCC protein overexpressed in gastric cancer, is regulated by multiple mechanisms including the ubiquitin-proteasome system. (PubMed id 21231912)1 Sugiura T. (Cell Biol. Int. 2011)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 11074 HGNC: 16289 AceView: TRIM31 Ensembl:ENSG00000204616 euGenes: HUgn11074
    ECgene: TRIM31 H-InvDB: TRIM31

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TRIM31 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TRIM31 gene:
    Search GeneIP for patents involving TRIM31

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