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TRIM29 Gene

protein-coding   GIFtS: 57
GCID: GC11M119981

Tripartite Motif Containing 29

(Previous name: tripartite motif-containing 29)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Tripartite Motif Containing 291 2     Ataxia Telangiectasia Group D-Associated Protein2 3
Tripartite Motif-Containing 291 2     ATDC2 3
Ataxia-Telangiectasia Group D-Associated Protein1 2     Tripartite Motif-Containing Protein 292
Tripartite Motif Protein TRIM291 2     

External Ids:    HGNC: 172741   Entrez Gene: 236502   Ensembl: ENSG000001376997   OMIM: 6106585   UniProtKB: Q141343   

Export aliases for TRIM29 gene to outside databases

Previous GC identifers: GC11M121981 GC11M121493 GC11M120015 GC11M119520 GC11M119521 GC11M119487 GC11M115921


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for TRIM29 Gene:
The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a
leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid
binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or
differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia
telangiectasia phenotype. (provided by RefSeq, Jul 2008)

GeneCards Summary for TRIM29 Gene:
TRIM29 (tripartite motif containing 29) is a protein-coding gene. Diseases associated with TRIM29 include ataxia telangiectasia, and ataxia. GO annotations related to this gene include p53 binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ENSG00000251537.

UniProtKB/Swiss-Prot: TRI29_HUMAN, Q14134
Function: It is able to complement the radiosensitivity defect of an ataxia telangiectasia (AT) fibroblast cell
line

Gene Wiki entry for TRIM29 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000011.10  NT_033899.9  NC_018922.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the TRIM29 gene promoter:
         Egr-3   HFH-3   Tal-1beta   GATA-2   E47   Egr-2   AREB6   FOXI1   S8   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTRIM29 promoter sequence
   Search Chromatin IP Primers for TRIM29

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TRIM29


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 11q23.3   Ensembl cytogenetic band:  11q23.3   HGNC cytogenetic band: 11q23.3

TRIM29 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TRIM29 gene location

GeneLoc information about chromosome 11         GeneLoc Exon Structure

GeneLoc location for GC11M119981:  view genomic region     (about GC identifiers)

Start:
119,981,983 bp from pter      End:
120,056,237 bp from pter
Size:
74,255 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TRI29_HUMAN, Q14134 (See protein sequence)
Recommended Name: Tripartite motif-containing protein 29  
Size: 588 amino acids; 65835 Da
Subunit: Interacts with VIM and HINT1
1 PDB 3D structure from and Proteopedia for TRIM29:
2CSV (3D)    
Secondary accessions: Q96AA9 Q9BZY7
Alternative splicing: 2 isoforms:  Q14134-1   Q14134-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for TRIM29: NX_Q14134

Explore proteomics data for TRIM29 at MOPED

Post-translational modifications: 

  • Constitutively phosphorylated by PKC on serine/threonine in A431 cells1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TRIM29 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_036233.2  
    ENSEMBL proteins: 
     ENSP00000343129   ENSP00000431869   ENSP00000437078   ENSP00000433122   ENSP00000432285  
     ENSP00000435696   ENSP00000436015   ENSP00000433779   ENSP00000431790   ENSP00000436279  
     ENSP00000435600   ENSP00000433324   ENSP00000436567   ENSP00000433084   ENSP00000445638  

    TRIM29 Human Recombinant Protein Products:

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    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

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    TRIM29 Assay Products:

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    Browse CLIAs at Cloud-Clone Corp.


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    TRIM: Tripartite motif containing / Tripartite motif containing

    1 InterPro protein domain:
     IPR000315 Znf_B-box

    Graphical View of Domain Structure for InterPro Entry Q14134

    ProtoNet protein and cluster: Q14134

    1 Blocks protein domain: IPB000315 B-box zinc finger signature

    UniProtKB/Swiss-Prot: TRI29_HUMAN, Q14134
    Similarity: Contains 1 B box-type zinc finger


    TRIM29 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TRI29_HUMAN, Q14134
    Function: It is able to complement the radiosensitivity defect of an ataxia telangiectasia (AT) fibroblast cell
    line

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0002039p53 binding IEA--
    GO:0003700sequence-specific DNA binding transcription factor activity TAS8188213
    GO:0005515protein binding IPI16189514
    GO:0008270zinc ion binding IEA--
         
    TRIM29 for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI phenotypic allele for Trim29 (no phenotypes)

    TRIM29 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TRIM29
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    miRTarBase miRNAs that target TRIM29:
    hsa-mir-124-3p (MIRT002561), hsa-mir-335-5p (MIRT018621), hsa-mir-122-5p (MIRT023394)

    Block miRNA regulation of human, mouse, rat TRIM29 using miScript Target Protectors
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TRI29_HUMAN, Q14134: Cytoplasm. Note=Colocalizes with intermediate filaments
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2
    golgi apparatus2
    cytoskeleton1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005737cytoplasm IEA--

    TRIM29 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for TRIM29 About    
    See pathways by source

    SuperPathContained pathways About
    1Cell Cycle / Checkpoint Control
    DNA Damage0.32

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 Cell Signaling Technology (CST) Pathway for TRIM29
        DNA Damage



    TRIM29 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TRIM29
    Interactions:

        Search GeneGlobe Interaction Network for TRIM29

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for TRIM29 (Q141341, 2, 3 ENSP000003431294) via UniProtKB, MINT, STRING, and/or I2D (see all 54)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CEP70Q8NHQ12, 3, ENSP000002649824MINT-67676 I2D: score=5 STRING: ENSP00000264982
    EFCAB4BQ9BSW22, 3, ENSP000004093824MINT-66038 I2D: score=5 STRING: ENSP00000409382
    FXR2P511162, 3, ENSP000002501134MINT-67829 I2D: score=5 STRING: ENSP00000250113
    JAKMIP2Q96AA82, 3, ENSP000002652724MINT-68356 I2D: score=5 STRING: ENSP00000265272
    MAD1L1Q9Y6D92, 3, ENSP000003825624MINT-68034 I2D: score=5 STRING: ENSP00000382562
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IEA--
    GO:0006366transcription from RNA polymerase II promoter TAS8188213
    GO:1900181negative regulation of protein localization to nucleus IEA--

    TRIM29 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TRIM29 (TRI29)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for TRIM29 gene (2 alternative transcripts): 
    NM_012101.3  NM_058193.1  

    Unigene Cluster for TRIM29:

    Tripartite motif containing 29
    Hs.504115  [show with all ESTs]
    Unigene Representative Sequence: BX648072
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 21):
    ENST00000341846(uc001pwx.3 uc010rzi.2 uc010rzj.2 uc001pwz.3 uc001pxa.3)
    ENST00000524816 ENST00000526161 ENST00000530919 ENST00000524664 ENST00000525887
    ENST00000533302 ENST00000531555 ENST00000525327 ENST00000528870 ENST00000529044
    ENST00000475051 ENST00000524956 ENST00000526881 ENST00000530470 ENST00000532195
    ENST00000529011 ENST00000529495
    miRNA
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      QuantiTect SYBR Green Assays in human, mouse, rat TRIM29
      QuantiFast Probe-based Assays in human, mouse, rat TRIM29

    Additional mRNA sequence: 

    AF230388.1 AK093404.1 AK122720.1 AK223090.1 AK299459.1 AK299472.1 AK303969.1 AL832678.1 
    BC010644.1 BC017352.2 BX648072.1 L24203.1 

    Selected DOTS entries (see all 25):

    DT.100840291  DT.215763  DT.92450158  DT.100792033  DT.100792028  DT.95112703  DT.101983193  DT.100792026 
    DT.95169901  DT.91679365  DT.86855491  DT.95169966  DT.100831593  DT.120746901  DT.95169900  DT.92450155 
    DT.95169967  DT.120746950  DT.120746957  DT.91934755  DT.95169899  DT.95169902  DT.100696689  DT.100792036 

    Selected AceView cDNA sequences (see all 263):

    BF914385 BG697403 BG697598 AA586872 CB125982 BG742909 BG741793 W61127 
    BQ025760 CR609266 AI620918 BI260963 AI972715 BC017352 AI961945 CB127464 
    AI961879 AI218870 BG696852 BM784162 BG679387 AL542780 BM836761 NM_012101 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for TRIM29 (see all 15)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c ^ 5a · 5b ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14a · 14b ^ 15 ^ 16a · 16b ^ 17 ^ 18a · 18b ·
    SP1:        -     -                                         -     -                 -     -           -           -     -                                       
    SP2:        -     -                                         -     -                 -     -           -           -     -                       -               
    SP3:                                                              -                 -     -           -           -     -                       -               
    SP4:                                                                                -     -           -           -     -                       -               
    SP5:                                                                                -     -           -           -                             -               

    ExUns: 18c · 18d · 18e · 18f · 18g ^ 19a · 19b
    SP1:                                          
    SP2:                                          
    SP3:                                          
    SP4:                                          
    SP5:                                          


    ECgene alternative splicing isoforms for TRIM29

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TRIM29 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTGCATATCA
    TRIM29 Expression
    About this image


    TRIM29 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 10) fully expand
     
     Thymus (Hematopoietic System)
             Thymus
     
     Gut Tube (Gastrointestinal Tract)
             Foregut
     
     Eye (Sensory Organs)
             Corneal Epithelium
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Lung (Respiratory System)
             Basal Cells Trachea
    TRIM29 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TRIM29 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.504115

    UniProtKB/Swiss-Prot: TRI29_HUMAN, Q14134
    Tissue specificity: Expressed in placenta, prostate and thymus

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIM29

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for TRIM29 gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Trim291 , 5 tripartite motif-containing 291, 5 86.71(n)1
    89.61(a)1
      9 (24.28 cM)5
    721691  NM_023655.21  NP_076144.21 
     433107635 
    chicken
    (Gallus gallus)
    Aves TRIM291 tripartite motif-containing 29 67.73(n)
    64.77(a)
      419754  XM_417892.4  XP_417892.4 
    lizard
    (Anolis carolinensis)
    Reptilia TRIM296
    tripartite motif containing 29
    57(a)
    1 ↔ 1
    LGa(1090405-1146967)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC534842 similar to tripartite motif protein 29 73.29(n)    BC044714.1 
    zebrafish
    (Danio rerio)
    Actinopterygii TRIM29 (38 of 87)6
    ftr196
    (see all 87)
    finTRIM family, member 19
    (see all 87)
    30(a)
    29(a)
    (see all 87)
    1 ↔ many
    1 ↔ many
    (see all 87)
    2(47967748-47968739) ENSDARG00000067986
    2(47957088-47958388) ENSDARG00000052955


    ENSEMBL Gene Tree for TRIM29 (if available)
    TreeFam Gene Tree for TRIM29 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TRIM29 gene
    ENSG000002515372  TRIM252  TRIM16L2  TRIM472  TRIM162  TRIM652  

    TRIM29 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TRIM29 (see all 647)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 11 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0359624
    A breast cancer sample4--see VAR_0359622 S F mis40--------
    rs1148884821,2
    C,F--119981678(+) GGGAAC/TTCTAG 1 -- ds50011Minor allele frequency- T:0.04WA 118
    rs1883293531,2
    --119981690(+) GTGGGC/TCGGCC 1 -- ds50010--------
    rs1401585031,2
    C--119981694(+) GCCGGC/TCAGAA 1 -- ds50010--------
    rs1503556901,2
    C--119981740(+) CAGGCA/CCACAC 1 -- ds50010--------
    rs107365021,2
    C,F,A,H--119981785(+) AAGGCC/GTGCCT 1 -- ds500115Minor allele frequency- G:0.19NS EA NA WA CSA 797
    rs1912463731,2
    --119981871(+) AGCCAC/TGTTTC 1 -- ds50010--------
    rs108925421,2
    C,F,A,H--119981906(+) GTGCCT/CTCATC 1 -- ds500114Minor allele frequency- C:0.05NS EA NA 1706
    rs1842613941,2
    --119982039(+) TGGATA/GTCTCC 1 -- ut310--------
    rs1143750481,2
    C,F--119982089(+) CCCATA/GGGCCT 1 -- ut311Minor allele frequency- G:0.02WA 118

    HapMap Linkage Disequilibrium report for TRIM29 (119981983 - 120056237 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for TRIM29:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2673699CNV Deletion23128226
    esv2745143CNV Deletion23290073

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TRIM29
    DNA2.0 Custom Variant and Variant Library Synthesis for TRIM29

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610658    OMIM disorders: --

    13 diseases for TRIM29:    
    About MalaCards
    ataxia telangiectasia    ataxia    esophageal squamous cell carcinoma    breast and colorectal cancer
    esophagitis    squamous cell carcinoma    pancreatic cancer    pancreatitis
    tonsillitis    lung cancer    colorectal cancer    breast cancer
    prostatitis

    1 disease from the University of Copenhagen DISEASES database for TRIM29:
    Ataxia telangiectasia

    TRIM29 for disorders           About GeneDecksing

    Genetic Association Database (GAD): TRIM29
    Human Genome Epidemiology (HuGE) Navigator: TRIM29 (2 documents)

    Export disorders for TRIM29 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TRIM29 gene, integrated from 10 sources (see all 41):
    (articles sorted by number of sources associating them with TRIM29)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The tripartite motif family identifies cell compartments. (PubMed id 11331580)1, 2, 3 Reymond A.... Ballabio A. (EMBO J. 2001)
    2. Expression of the ATDC (ataxia telangiectasia group D-complementing) gene in A431 human squamous carcinoma cells. (PubMed id 8647648)1, 2, 9 Laderoute K.R.... Kapp L.N. (Int. J. Cancer 1996)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. A probability-based approach for high-throughput protein phosphorylation analysis and site localization. (PubMed id 16964243)1, 2 Beausoleil S.A.... Gygi S.P. (Nat. Biotechnol. 2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. The product of the ataxia-telangiectasia group D complementing gene, ATDC, interacts with a protein kinase C substrate and inhibitor. (PubMed id 7644499)1, 2 Brzoska P.M.... Christman M.F. (Proc. Natl. Acad. Sci. U.S.A. 1995)
    7. Nucleotide sequence analysis of a candidate gene for ataxia- telangiectasia group D (ATDC). (PubMed id 8188213)1, 2 Leonhardt E.A.... Murnane J.P. (Genomics 1994)
    8. The ATDC (TRIM29) protein binds p53 and antagonizes p53-mediated functions. (PubMed id 20368352)1, 9 Yuan Z....Seto E. (Mol. Cell. Biol. 2010)
    9. Suppression of anchorage-independent growth by expression of the ataxia-telangiectasia group D complementing gene, ATDC. (PubMed id 16890201)1, 9 Hosoi Y....Miyagawa K. (Biochem. Biophys. Res. Commun. 2006)
    10. Oncogenic function of ATDC in pancreatic cancer through Wnt pathway activation and beta-catenin stabilization. (PubMed id 19249679)1, 9 Wang L....Simeone D.M. (Cancer Cell 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 23650 HGNC: 17274 AceView: TRIM29 Ensembl:ENSG00000137699 euGenes: HUgn23650
    ECgene: TRIM29 H-InvDB: TRIM29

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TRIM29 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for TRIM29 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TRIM29 gene:
    Search GeneIP for patents involving TRIM29

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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