Aliases for TRIM29 Gene
External Ids for TRIM29 Gene
Previous GeneCards Identifiers for TRIM29 Gene
The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype. [provided by RefSeq, Jul 2008]
GeneCards Summary for TRIM29 Gene
TRIM29 (Tripartite Motif Containing 29) is a Protein Coding gene. Diseases associated with TRIM29 include Ataxia-Telangiectasia. Among its related pathways are Interleukin-3, 5 and GM-CSF signaling and Interferon gamma signaling. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and p53 binding. An important paralog of this gene is TRIM47.
UniProtKB/Swiss-Prot for TRIM29 Gene
It is able to complement the radiosensitivity defect of an ataxia telangiectasia (AT) fibroblast cell line.