Aliases for TRIM29 Gene
External Ids for TRIM29 Gene
The protein encoded by this gene belongs to the TRIM protein family. It has multiple zinc finger motifs and a leucine zipper motif. It has been proposed to form homo- or heterodimers which are involved in nucleic acid binding. Thus, it may act as a transcriptional regulatory factor involved in carcinogenesis and/or differentiation. It may also function in the suppression of radiosensitivity since it is associated with ataxia telangiectasia phenotype. [provided by RefSeq, Jul 2008]
GeneCards Summary for TRIM29 Gene
TRIM29 (Tripartite Motif Containing 29) is a Protein Coding gene. Diseases associated with TRIM29 include ataxia. Among its related pathways are Cell Cycle / Checkpoint Control. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity and p53 binding. An important paralog of this gene is TRIM16L.
UniProtKB/Swiss-Prot for TRIM29 Gene
It is able to complement the radiosensitivity defect of an ataxia telangiectasia (AT) fibroblast cell line