Aliases for TRIM26 Gene
External Ids for TRIM26 Gene
Previous HGNC Symbols for TRIM26 Gene
Previous GeneCards Identifiers for TRIM26 Gene
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Although the function of the protein is unknown, the RING domain suggests that the protein may have DNA-binding activity. The gene localizes to the major histocompatibility complex (MHC) class I region on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2011]
GeneCards Summary for TRIM26 Gene
TRIM26 (Tripartite Motif Containing 26) is a Protein Coding gene. Diseases associated with TRIM26 include Neural Tube Defects and Seizure Disorder. Among its related pathways are Interleukin-3, 5 and GM-CSF signaling and Interferon gamma signaling. An important paralog of this gene is TRIM10.