Aliases for TRIM26 Gene
External Ids for TRIM26 Gene
Previous HGNC Symbols for TRIM26 Gene
Previous GeneCards Identifiers for TRIM26 Gene
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic bodies. Although the function of the protein is unknown, the RING domain suggests that the protein may have DNA-binding activity. The gene localizes to the major histocompatibility complex (MHC) class I region on chromosome 6. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2011]
GeneCards Summary for TRIM26 Gene
TRIM26 (Tripartite Motif Containing 26) is a Protein Coding gene. Diseases associated with TRIM26 include endodermal sinus tumor and seizure disorder. Among its related pathways are Hippo signaling pathway and Glucocorticoid receptor regulatory network. An important paralog of this gene is TRIM50.