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Aliases for TRIM16L Gene

Aliases for TRIM16L Gene

  • Tripartite Motif Containing 16-Like 2 3 5
  • Tripartite Motif-Containing Protein 70 3 4
  • Tripartite Motif-Containing 16-Like 2 3
  • TRIM70 3 4
  • Tripartite Motif Protein 70 3

External Ids for TRIM16L Gene

Previous GeneCards Identifiers for TRIM16L Gene

  • GC17P018547
  • GC17P018602

Summaries for TRIM16L Gene

GeneCards Summary for TRIM16L Gene

TRIM16L (Tripartite Motif Containing 16-Like) is a Protein Coding gene. An important paralog of this gene is TRIM29.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRIM16L Gene

Genomics for TRIM16L Gene

Regulatory Elements for TRIM16L Gene

Enhancers for TRIM16L Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around TRIM16L on UCSC Golden Path with GeneCards custom track

Promoters for TRIM16L Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around TRIM16L on UCSC Golden Path with GeneCards custom track

Genomic Location for TRIM16L Gene

18,697,998 bp from pter
18,736,118 bp from pter
38,121 bases
Plus strand

Genomic View for TRIM16L Gene

Genes around TRIM16L on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRIM16L Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRIM16L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRIM16L Gene

Proteins for TRIM16L Gene

  • Protein details for TRIM16L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Tripartite motif-containing protein 16-like protein
    Protein Accession:
    Secondary Accessions:
    • A0PK10
    • B2RUW6
    • B4DQK2
    • B4DWQ8

    Protein attributes for TRIM16L Gene

    348 amino acids
    Molecular mass:
    40306 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for TRIM16L Gene


neXtProt entry for TRIM16L Gene

Proteomics data for TRIM16L Gene at MOPED

Post-translational modifications for TRIM16L Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for TRIM16L Gene

Domains & Families for TRIM16L Gene

Protein Domains for TRIM16L Gene

Suggested Antigen Peptide Sequences for TRIM16L Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 B30.2/SPRY domain.
  • Belongs to the TRIM/RBCC family.
  • Contains 1 B30.2/SPRY domain.
  • Belongs to the TRIM/RBCC family.
genes like me logo Genes that share domains with TRIM16L: view

No data available for Gene Families for TRIM16L Gene

Function for TRIM16L Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for TRIM16L Gene

Localization for TRIM16L Gene

Subcellular locations from UniProtKB/Swiss-Prot for TRIM16L Gene


Subcellular locations from

Jensen Localization Image for TRIM16L Gene COMPARTMENTS Subcellular localization image for TRIM16L gene
Compartment Confidence
cytosol 3
nucleus 2
peroxisome 1

No data available for Gene Ontology (GO) - Cellular Components for TRIM16L Gene

Pathways & Interactions for TRIM16L Gene

SuperPathways for TRIM16L Gene

No Data Available

Interacting Proteins for TRIM16L Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000379030 Q309B1-TR16L_HUMAN for TRIM16L Gene via STRING I2D

Gene Ontology (GO) - Biological Process for TRIM16L Gene


No data available for Pathways by source and SIGNOR curated interactions for TRIM16L Gene

Drugs & Compounds for TRIM16L Gene

No Compound Related Data Available

Transcripts for TRIM16L Gene

Unigene Clusters for TRIM16L Gene

Tripartite motif containing 16-like:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for TRIM16L Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c ^ 9 ^ 10 ^ 11a · 11b · 11c ^ 12a · 12b · 12c ^ 13a · 13b · 13c
SP1: - - - - - - -
SP2: - - - - -
SP3: - - -
SP4: - - - - - - -
SP5: - - - - -
SP6: - -
SP7: -
SP8: -

Relevant External Links for TRIM16L Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TRIM16L Gene

mRNA expression in normal human tissues for TRIM16L Gene

Protein differential expression in normal tissues from HIPED for TRIM16L Gene

This gene is overexpressed in Cervix (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TRIM16L Gene

SOURCE GeneReport for Unigene cluster for TRIM16L Gene Hs.745311

genes like me logo Genes that share expression patterns with TRIM16L: view

Protein tissue co-expression partners for TRIM16L Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TRIM16L Gene

Orthologs for TRIM16L Gene

This gene was present in the common ancestor of chordates.

Orthologs for TRIM16L Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia TRIM16L 35
  • 98.66 (n)
  • 97.13 (a)
TRIM16L 36
  • 64 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 41 (a)
(Mus musculus)
Mammalia Trim16 36
  • 53 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 66 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 35 (a)
(Danio rerio)
Actinopterygii trim16 36
  • 27 (a)
Species with no ortholog for TRIM16L:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TRIM16L Gene

Gene Tree for TRIM16L (if available)
Gene Tree for TRIM16L (if available)

Paralogs for TRIM16L Gene

Paralogs for TRIM16L Gene

(2) SIMAP similar genes for TRIM16L Gene using alignment to 7 proteins:

genes like me logo Genes that share paralogs with TRIM16L: view

Variants for TRIM16L Gene

Sequence variations from dbSNP and Humsavar for TRIM16L Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs163367 -- 18,715,331(+) CCACC(A/G)CCCCC intron-variant
rs998620 -- 18,722,004(+) GTGAG(C/T)AGCAC intron-variant, upstream-variant-2KB
rs1004013 -- 18,723,887(-) CTCCC(A/C)TTGAG intron-variant
rs1809883 -- 18,719,035(+) TGCTA(A/G)GGTGT intron-variant, upstream-variant-2KB
rs1846533 -- 18,696,073(-) TTGTG(A/T)ATGTC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for TRIM16L Gene

Variant ID Type Subtype PubMed ID
nsv9504 CNV Gain+Loss 18304495
nsv907782 CNV Gain 21882294
nsv499818 OTHER Inversion 21111241
nsv833389 CNV Gain 17160897
nsv523721 CNV Gain 19592680
nsv112212 CNV Loss 16902084
esv2715724 CNV Deletion 23290073
esv1199476 CNV Deletion 17803354

Variation tolerance for TRIM16L Gene

Residual Variation Intolerance Score: 91.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 7.82; 83.46% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for TRIM16L Gene

Disorders for TRIM16L Gene

Relevant External Links for TRIM16L

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for TRIM16L Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TRIM16L Gene

Publications for TRIM16L Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for TRIM16L Gene

Sources for TRIM16L Gene