Aliases for TRIM16 Gene
External Ids for TRIM16 Gene
Previous GeneCards Identifiers for TRIM16 Gene
The protein encoded by this gene is a tripartite motif (TRIM) family member that contains two B box domains and a coiled-coiled region that are characteristic of the B box zinc finger protein family. While it lacks a RING domain found in other TRIM proteins, the encoded protein can homodimerize or heterodimerize with other TRIM proteins and has E3 ubiquitin ligase activity. This gene is also a tumor suppressor and is involved in secretory autophagy. [provided by RefSeq, Jan 2017]
GeneCards Summary for TRIM16 Gene
TRIM16 (Tripartite Motif Containing 16) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and NACHT domain binding. An important paralog of this gene is TRIM16L.
UniProtKB/Swiss-Prot for TRIM16 Gene
May play a role in the regulation of keratinocyte differentiation.