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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

TRIM15 Gene

protein-coding   GIFtS: 51
GCID: GC06P030130

Tripartite Motif Containing 15

(Previous names: zinc finger protein 178, tripartite motif-containing 15)
(Previous symbol: ZNF178)
  3 related diseases
at
MalaCards
 

Aliases
for TRIM15 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section
Aliases
Tripartite Motif Containing 151 2     RNF932 3
Zinc Finger Protein 1781 2 3     ZNFB72 3
ZNF1781 2 3     RING Finger Protein 932 3
Tripartite Motif-Containing 151 2     Tripartite Motif-Containing Protein 152
Zinc Finger Protein B72 3     

External Ids:    HGNC: 162841   Entrez Gene: 898702   Ensembl: ENSG000002046107   UniProtKB: Q9C0193   

Export aliases for TRIM15 gene to outside databases

Previous GC identifers: GC06P030215 GC06P029901 GC06P030237 GC06P030238 GC06P029929


Summaries
for TRIM15 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for TRIM15 Gene:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three
zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to
the cytoplasm. Alternatively spliced transcript variants have been described, but their biological validity has not
been determined. (provided by RefSeq, Jul 2008)

GeneCards Summary for TRIM15 Gene: 
TRIM15 (tripartite motif containing 15) is a protein-coding gene. Diseases associated with TRIM15 include hemochromatosis, and systemic lupus erythematosus. GO annotations related to this gene include zinc ion binding. An important paralog of this gene is TRIM7.

Gene Wiki entry for TRIM15 Gene


Genomic Views
for TRIM15 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NT_007592.15  NT_113891.2  NT_167244.1  NT_167245.1  NT_167246.1  NT_167247.1  NT_167248.1  
NT_167249.1  NC_018917.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the TRIM15 gene promoter:
         Max1   AML1a   MyoD   Nkx2-5   c-Ets-1   Arnt   MZF-1   E2F-1   E2F   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): TRIM15 promoter sequence
   Search SABiosciences Chromatin IP Primers for TRIM15

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRIM15


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.3   Ensembl cytogenetic band:  6p22.1   HGNC cytogenetic band: 6p21.33

TRIM15 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TRIM15 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P030130:  view genomic region     (about GC identifiers)

Start:
 30,130,983 bp from pter      End:
 30,140,473 bp from pter
Size:
 9,491 bases      Orientation:
 plus strand

6/7 alternative locations (see all 7):
Chr6+,NT_167245 1,424,692-1,434,182      Chr6+,NT_113891.2 1,643,110-1,652,600      Chr6+,NT_167249 1,461,435-1,470,925     
Chr6+,NT_167247 1,512,864-1,522,354      Chr6+,NT_167248 1,423,930-1,433,420      Chr6+,NT_167246 1,479,528-1,489,018     

Proteins
for TRIM15 gene

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section
UniProtKB/Swiss-Prot: TRI15_HUMAN, Q9C019 (See protein sequence)
Recommended Name: Tripartite motif-containing protein 15  
Size: 465 amino acids; 52113 Da
Secondary accessions: A2BEC9 O95604 Q8IUX9 Q9C018
Alternative splicing: 2 isoforms:  Q9C019-1   Q9C019-2   

Explore the universe of human proteins at neXtProt for TRIM15: NX_Q9C019

Explore proteomics data for TRIM15 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9C019

    • TRIM15 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    TRIM15 Protein Expression
    REFSEQ proteins: NP_150232.2  
    ENSEMBL proteins: 
     ENSP00000365884   ENSP00000398285   ENSP00000365878  

    Human Recombinant Protein Products for TRIM15: 
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    OriGene Purified Protein for TRIM15
    OriGene Protein Over-expression Lysate for TRIM15
    OriGene MassSpec for TRIM15 
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    GenScript Custom Purified and Recombinant Proteins Services for TRIM15
    Novus Biologicals TRIM15 Protein
    Novus Biologicals TRIM15 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TRIM15 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular IEA--

    TRIM15 for ontologies           About GeneDecksing



    TRIM15 Antibody Products: 
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    LSBio Antibodies in human, mouse, rat for TRIM15 

    Assay Products for TRIM15: 
    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for TRIM15 
    Cloud-Clone Corp. CLIAs for TRIM15

    Protein Domains /
    Families
    for TRIM15 gene

    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    		 HGNC Gene Families: 
    TRIM: Tripartite motif containing / Tripartite motif containing
    RNF: RING-type (C3HC4) zinc fingers

    5/10 InterPro protein domains (see all 10):
     IPR006574 PRY
     IPR017907 Znf_RING_CS
     IPR001841 Znf_RING
     IPR001870 B30.2/SPRY
     IPR003877 SPRY_rcpt

    Graphical View of Domain Structure for InterPro Entry Q9C019

    ProtoNet protein and cluster: Q9C019

    4 Blocks protein domains:
    IPB000315 B-box zinc finger signature
    IPB001841 Zn-finger
    IPB003879 Butyrophylin C-terminal DUF signature
    IPB006574 SPRY-associated domain


    UniProtKB/Swiss-Prot: TRI15_HUMAN, Q9C019
    Similarity: Belongs to the TRIM/RBCC family
    Similarity: Contains 1 B box-type zinc finger
    Similarity: Contains 1 B30.2/SPRY domain
    Similarity: Contains 1 RING-type zinc finger


    TRIM15 for domains           About GeneDecksing


    Function
    for TRIM15 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--
    GO:0046872metal ion binding ----
         
    TRIM15 for ontologies           About GeneDecksing


    Phenotypes:
         4 GenomeRNAi human phenotypes for TRIM15:
     Decreased homologous recombina  Decreased viability with pacli  Increased cell death HMECs cel  Synthetic lethal with c-Myc af 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for TRIM15 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for TRIM15

    miRNA
    Products:        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TRIM15
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate TRIM15
    SwitchGear 3'UTR luciferase reporter plasmid: TRIM15 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TRIM15
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    Sirion Biotech Custom design and validation of potent shRNA sequences against TRIM15

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for TRIM15
    Sirion Biotech Customized adenovirus for overexpression of TRIM15
                         Customized adenovirus for potent knockdown of TRIM15

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for TRIM15 (see all 6)
    OriGene ORF clones in mouse, rat for TRIM15
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    GenScript: all cDNA clones in your preferred vector: TRIM15 (NM_033229)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TRIM15
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRIM15

    Cell Line
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    Search LifeMap BioReagents cell lines for TRIM15
    Sirion Biotech Customized stable knockdown cell line services for TRIM15
                         Customized inducible knockdown cell line services for TRIM15
                         Customized stable overexpressing cell line services for TRIM15
                         Customized inducible overexpressing cell line services for TRIM15

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIM15


    Pathways & Interactions
    for TRIM15 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TRIM15

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    5/9 Interacting proteins for TRIM15 (Q9C0193 ENSP000003658844) via UniProtKB, MINT, STRING, and/or I2D (see all 9)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBE2UQ5VVX93I2D: score=2 
    EHMT1Q9H9B13I2D: score=1 
    GTF2E1P290833I2D: score=1 
    IRF5Q135683I2D: score=1 
    MED7O435133I2D: score=1 
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007500mesodermal cell fate determination TAS10207104

    TRIM15 for ontologies           About GeneDecksing



    Drugs & Compounds
    for TRIM15 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, IUPHAR, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for TRIM15 (TRI15)

    Search CenterWatch for drugs/clinical trials and news about TRIM15 / TRI15

    Transcripts
    for TRIM15 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for TRIM15 gene (2 alternative transcripts): 
    NM_033229.2  NM_052812.1  

    Unigene Cluster for TRIM15:

    Tripartite motif containing 15
    Hs.591789  [show with all ESTs]
    Unigene Representative Sequence: U34249
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000376694(uc010jrx.3) ENST00000433744 ENST00000477944 ENST00000376688

    miRNA
    Products:         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TRIM15
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate TRIM15
    SwitchGear 3'UTR luciferase reporter plasmid: TRIM15 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for TRIM15
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TRIM15
    Sirion Biotech Custom design and validation of potent shRNA sequences against TRIM15
    Clone
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    OriGene ORF clones in mouse, rat for TRIM15
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TRIM15 (NM_033229)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TRIM15
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRIM15
    Primer
    Products:            		OriGene qSTAR qPCR primer pairs in human, mouse for TRIM15
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TRIM15
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRIM15
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRIM15

    Additional mRNA sequence: 

    AF220132.1 AF220133.1 AK290280.1 AK291853.1 BC038585.1 U34249.1 

    6 DOTS entries:

    DT.406377  DT.40233789  DT.75188956  DT.91755436  DT.121346054  DT.75165522 

    4 AceView cDNA sequences:

    AF220132 NM_033229 U34249 BC038585 

    GeneLoc Exon Structure


    Expression
    for TRIM15 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TRIM15 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCCCCTGTGC
    TRIM15 Expression
    About this image


    See TRIM15 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for TRIM15

    SOURCE GeneReport for Unigene cluster: Hs.591789
        SABiosciences Expression via Pathway-Focused PCR Array including TRIM15: 
              Polycomb & Trithorax Target Genes in human mouse rat

    Primer
    Products:    		OriGene qSTAR qPCR primer pairs in human, mouse for TRIM15
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat TRIM15
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRIM15
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRIM15
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIM15

    Orthologs
    for TRIM15 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for TRIM15 gene from 3/7 species (see all 7)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Trim151 , 5 tripartite motif-containing 151, 5 78.79(n)1
    76.22(a)1    		   17 (19.16 cM)5
    690971  NM_001177872.11  NP_001171343.11 
     368606935 
    chicken
    (Gallus gallus)    		 Aves TRIM7.26
    TRIM27.16
    		 tripartite motif-containing 27
    		 29(a)
    27(a)
    		 many ↔ many
    many ↔ many
    		 16(209966-214262)
    16(150525-169149)
    lizard
    (Anolis carolinensis)    		 Reptilia --
    --
    (see all 31)    		 Uncharacterized protein
    (see all 31)    		 34(a)
    33(a)
    (see all 31)    		 possible ortholog
    possible ortholog
    (see all 31)    		 2(198879184-198890512)
    2(195919842-195929549)


    ENSEMBL Gene Tree for TRIM15 (if available)
    TreeFam Gene Tree for TRIM15 (if available)

    Paralogs
    for TRIM15 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for TRIM15 gene
    TRIM72  TRIM42  TRIM262  TRIM392  TRIM342  TRIM272  TRIM582  TRIM682  
    TRIM102  TRIM602  TRIM222  TRIM172  TRIM52  TRIM62  TRIM6-TRIM342  TRIM212  
    TRIM382  TRIM112  TRIM39-RPP212  
    8 SIMAP similar genes for TRIM15 using alignment to 4 protein entries:     TRI15_HUMAN (see all proteins):
    ZNFB7    TRIM10    TRIM39R    TRIM7    TRIM38    TRIM27
    TRIM39    MEFV

    TRIM15 for paralogs           About GeneDecksing



    Genomic Variants
    for TRIM15 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/288 SNPs in TRIM15 are shown (see all 288)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 6 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1495244061,2
    		C--30130806(+) TGGTGA/GGGGAT 1 -- us2k10--------
    rs25176251,2
    		H--30130921(-) GGACGC/GTGTTT 1 -- us2k14Minor allele frequency- G:0.00NS EA 416
    rs171881131,2
    		C,F--30131123(+) CCTCAT/GGGTGT 1 -- ut51 ese33Minor allele frequency- G:0.20MN NA EA 336
    rs1891059111,2
    		--30131220(+) GAGACG/TCCCTG 1 -- ut510--------
    rs1462076811,2
    		--30131296(+) GGTGGA/CTTCCC 1 -- ut510--------
    rs2007209001,2
    		C--30131318(+) CTTGC-/CTCT  
                CTCTC     		1 -- ut510--------
    rs624074921,2
    		C--30131331(+) TCTCTC/TTCTCT 1 -- ut510--------
    rs92615361,2
    		C,F,A,H--30131349(+) TCTCTC/TAGCCT 1 -- ut51 ese329Minor allele frequency- T:0.06NS EA NA WA CSA 2781
    rs2015081911,2
    		C--30131468(+) TGCCCG/ACAACC 2 /T /A mis11Minor allele frequency- A:0.00EU 437
    rs1436287731,2
    		F--30131483(+) CCCTGA/GAGGTG 2 K E mis11Minor allele frequency- G:0.00NA 4472

    HapMap Linkage Disequilibrium report for TRIM15 (30130983 - 30140473 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for TRIM15:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2731777CNV Deletion23290073

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TRIM15
    DNA2.0 Custom Variant and Variant Library Synthesis for TRIM15

    Disorders / Diseases
    for TRIM15 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    TRIM15 for disorders           About GeneDecksing

    3 diseases for TRIM15:    About MalaCards
    hemochromatosis    systemic lupus erythematosus    lupus erythematosus

    Genetic Association Database (GAD): TRIM15
    Human Genome Epidemiology (HuGE) Navigator: TRIM15 (4 documents)

    Export disorders for TRIM15 gene to outside databases

    Publications
    for TRIM15 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for TRIM15 gene, integrated from 9 sources (see all 19):
    (articles sorted by number of sources associating them with TRIM15)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The tripartite motif family identifies cell compartments. (PubMed id 11331580)1, 2, 3 Reymond A.... Ballabio A. (2001)
    2. Isolation of novel non-HLA gene fragments from the hemochromatosis region (6p21.3) by cDNA hybridization selection. (PubMed id 8304341)1, 2, 3 Goei V.L.... Gruen J.R. (1994)
    3. Refining the association of MHC with multiple scleros is in African Americans. (PubMed id 20466734)1, 4 McElroy J.P....Gourraud P.A. (2010)
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    5. High-density SNP screening of the major histocompatib ility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PubMed id 19851445)1, 4 Barcellos L.F....Criswell L.A. (2009)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. A transcription map of the major histocompatibility c omplex (MHC) class I region. (PubMed id 8812418)1, 3 Gruen J.R....Weissman S.M. (1996)
    8. Systematic analysis of dimeric E3-RING interactions re veals increased combinatorial complexity in human ubiquitination networks. (PubMed id 22493164)1 Woodsmith J....Sanderson C.M. (2012)
    9. Genome-wide YFP fluorescence complementation screen id entifies new regulators for telomere signaling in human cells. (PubMed id 21044950)1 Lee O.H....Songyang Z. (2011)
    10. An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)1 Ravasi T....Hayashizaki Y. (2010)

    External Searches for TRIM15 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
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    Genome Databases showing TRIM15 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 89870 HGNC: 16284 AceView: TRIM15 Ensembl:ENSG00000204610 euGenes: HUgn89870
    ECgene: TRIM15 H-InvDB: TRIM15

    Other Databases showing TRIM15 gene

    (According to HUGE)
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    Specialized Databases showing TRIM15 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for TRIM15 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for TRIM15 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for TRIM15 gene:
    Search GeneIP for patents involving TRIM15

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