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TRIM10 Gene

protein-coding   GIFtS: 47
GCID: GC06M030119

Tripartite Motif Containing 10

(Previous name: tripartite motif-containing 10)
(Previous symbol: RNF9)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Tripartite Motif Containing 101 2     HERF12 5
RNF91 2 3 5     Hematopoietic RING Finger 12
RFB302 3 5     Tripartite Motif Protein 102
Tripartite Motif-Containing 101 2     Tripartite Motif-Containing Protein 102
RING Finger Protein 92 3     Zn-Finger Protein2
B30-RING Finger Protein2 3     

External Ids:    HGNC: 100721   Entrez Gene: 101072   Ensembl: ENSG000002046137   OMIM: 6057015   UniProtKB: Q9UDY63   

Export aliases for TRIM10 gene to outside databases

Previous GC identifers: GC06M030204 GC06M029890 GC06M030225 GC06M030227 GC06M029918


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for TRIM10 Gene:
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three
zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes
to cytoplasmic bodies. Studies in mice suggest that this protein plays a role in terminal differentiation of
erythroid cells. Alternate splicing of this gene generates two transcript variants encoding different isoforms.
(provided by RefSeq, Jul 2008)

GeneCards Summary for TRIM10 Gene:
TRIM10 (tripartite motif containing 10) is a protein-coding gene. An important paralog of this gene is TRIM31.

UniProtKB/Swiss-Prot: TRI10_HUMAN, Q9UDY6
Function: Seems to play an important role in erythropoiesis (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the TRIM10 gene promoter:
         Max1   NF-1/L   MyoD   Nkx2-5   c-Ets-1   Arnt   MZF-1   E2F-1   E2F   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTRIM10 promoter sequence
   Search Chromatin IP Primers for TRIM10

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TRIM10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.3   Ensembl cytogenetic band:  6p22.1   HGNC cytogenetic band: 6p21.3

TRIM10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TRIM10 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M030119:  view genomic region     (about GC identifiers)

Start:
30,119,722 bp from pter      End:
30,128,711 bp from pter
Size:
8,990 bases      Orientation:
minus strand

Selected alternative locations (see all 7):
Chr6-,NT_113891.2 1,631,859-1,640,846      Chr6-,NT_167244 1,359,957-1,368,945      Chr6-,NT_167249 1,450,168-1,459,159     
Chr6-,NT_167247 1,501,605-1,510,596      Chr6-,NT_167246 1,468,287-1,477,275      Chr6-,NT_167245 1,413,447-1,422,435     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: TRI10_HUMAN, Q9UDY6 (See protein sequence)
Recommended Name: Tripartite motif-containing protein 10  
Size: 481 amino acids; 55037 Da
Secondary accessions: A6NF84 Q5SRJ5 Q5SRK8 Q86Z08 Q96QB6 Q9C023 Q9C024
Alternative splicing: 2 isoforms:  Q9UDY6-1   Q9UDY6-2   (Ref.2 (AAG53496) sequence is in conflict in position: 379:C->G)

Explore the universe of human proteins at neXtProt for TRIM10: NX_Q9UDY6

Explore proteomics data for TRIM10 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TRIM10 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_006769.2  NP_439893.2  

    ENSEMBL proteins: 
     ENSP00000397073   ENSP00000365894  

    TRIM10 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    OriGene Purified Protein for TRIM10
    OriGene Protein Over-expression Lysate for TRIM10
    OriGene MassSpec for TRIM10
    OriGene Custom Protein Services for TRIM10
    GenScript Custom Purified and Recombinant Proteins Services for TRIM10
    Novus Biologicals TRIM10 Proteins
    Novus Biologicals TRIM10 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for TRIM10

     
    Search eBioscience for Proteins for TRIM10 

     
    antibodies-online proteins for TRIM10 (9 products) 

     
    antibodies-online peptides for TRIM10

    TRIM10 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Novus Biologicals TRIM10 Antibodies
    Abcam antibodies for TRIM10
    Cloud-Clone Corp. Antibodies for TRIM10
    ThermoFisher Antibodies for TRIM10
    LSBio Antibodies in human, mouse, rat for TRIM10
    antibodies-online antibodies for TRIM10 (31 products) 

    TRIM10 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for TRIM10
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for TRIM10
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for TRIM10
    Cloud-Clone Corp. CLIAs for TRIM10
    Search eBioscience for ELISAs for TRIM10 
    antibodies-online kits for TRIM10 (8 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    TRIM: Tripartite motif containing / Tripartite motif containing
    RNF: RING-type (C3HC4) zinc fingers

    Selected InterPro protein domains (see all 10):
     IPR006574 PRY
     IPR017907 Znf_RING_CS
     IPR001841 Znf_RING
     IPR001870 B30.2/SPRY
     IPR003877 SPRY_rcpt

    Graphical View of Domain Structure for InterPro Entry Q9UDY6

    ProtoNet protein and cluster: Q9UDY6

    4 Blocks protein domains:
    IPB000315 B-box zinc finger signature
    IPB001841 Zn-finger
    IPB003879 Butyrophylin C-terminal DUF signature
    IPB006574 SPRY-associated domain


    UniProtKB/Swiss-Prot: TRI10_HUMAN, Q9UDY6
    Similarity: Belongs to the TRIM/RBCC family
    Similarity: Contains 1 B box-type zinc finger
    Similarity: Contains 1 B30.2/SPRY domain
    Similarity: Contains 1 RING-type zinc finger


    Find genes that share domains with TRIM10           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TRI10_HUMAN, Q9UDY6
    Function: Seems to play an important role in erythropoiesis (By similarity)

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
    GO:0005515protein binding ----
    GO:0008270zinc ion binding IEA--
    GO:0046872metal ion binding ----
         
    Find genes that share ontologies with TRIM10           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TRIM10
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for TRIM10

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TRIM10
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TRIM10

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat TRIM10 using miScript Target Protectors
    4 qRT-PCR Assays for microRNAs that regulate TRIM10:
    hsa-miR-612 hsa-miR-1285 hsa-miR-103a-2* hsa-miR-877
    SwitchGear 3'UTR luciferase reporter plasmidTRIM10 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for TRIM10
    Predesigned siRNA for gene silencing in human, mouse, rat TRIM10

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for TRIM10

    Clone
    Products:
         
    OriGene clones in human, mouse for TRIM10 (see all 10)
    OriGene ORF clones in mouse, rat for TRIM10
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): TRIM10 (NM_052828)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TRIM10
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRIM10

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for TRIM10
    Browse ESI BIO Cell Lines and PureStem Progenitors for TRIM10 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIM10


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TRI10_HUMAN, Q9UDY6: Cytoplasm
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005737cytoplasm ISS--

    Find genes that share ontologies with TRIM10           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Pathway & Disease-focused RT2 Profiler PCR Arrays including TRIM10: 
              Polycomb & Trithorax Target Genes in human mouse rat
              Ubiquitin Ligases in human mouse rat
              Molecular Toxicology PathwayFinder 384HT in human mouse rat
              Hematopoiesis in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for TRIM10

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for TRIM10 (ENSP000003970734) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000235025ENSP000003955984STRING: ENSP00000395598
    About this table

    Gene Ontology (GO): 2 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--
    GO:0030218erythrocyte differentiation IEA--

    Find genes that share ontologies with TRIM10           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TRIM10 (TRI10)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TRIM10 gene (2 alternative transcripts): 
    NM_006778.3  NM_052828.2  

    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000449742(uc003npo.3) ENST00000376704(uc003npn.2)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat TRIM10 using miScript Target Protectors
    4 qRT-PCR Assays for microRNAs that regulate TRIM10:
    hsa-miR-612 hsa-miR-1285 hsa-miR-103a-2* hsa-miR-877
    SwitchGear 3'UTR luciferase reporter plasmidTRIM10 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for TRIM10
    Predesigned siRNA for gene silencing in human, mouse, rat TRIM10
    Clone
    Products:
         
    OriGene clones in human, mouse for TRIM10 (see all 10)
    OriGene ORF clones in mouse, rat for TRIM10
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): TRIM10 (NM_052828)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TRIM10
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRIM10
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for TRIM10
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TRIM10
      QuantiTect SYBR Green Assays in human, mouse, rat TRIM10
      QuantiFast Probe-based Assays in human, mouse, rat TRIM10

    Selected AceView cDNA sequences (see all 57):

    AA733026 BX494330 H59223 AA004608 BX405576 H58199 BX497949 BX106141 
    AA723050 AA723071 AI240570 AI566746 BX371998 AI248753 R10283 BX494456 
    NM_006778 AA706979 AA004526 N91641 NM_052828 BX494288 BX107289 BX328078 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TRIM10 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGTCCTGGCG
    TRIM10 Expression
    About this image


    TRIM10 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Blood (Hematopoietic System)
             Erythroblasts Hematopoietic Bone Marrow
    TRIM10 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TRIM10 Protein Expression
        Pathway & Disease-focused RT2 Profiler PCR Arrays including TRIM10: 
              Polycomb & Trithorax Target Genes in human mouse rat
              Ubiquitin Ligases in human mouse rat
              Molecular Toxicology PathwayFinder 384HT in human mouse rat
              Hematopoiesis in human mouse rat

    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for TRIM10
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TRIM10
    QuantiTect SYBR Green Assays in human, mouse, rat TRIM10
    QuantiFast Probe-based Assays in human, mouse, rat TRIM10
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIM10

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of human and mouse.

    Orthologs for TRIM10 gene from Selected species (see all 6)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Trim101 , 5 tripartite motif-containing 101, 5 82.99(n)1
    84.37(a)1
      17 (19.16 cM)5
    198241  NM_011280.21  NP_035410.21 
     368695745 


    ENSEMBL Gene Tree for TRIM10 (if available)
    TreeFam Gene Tree for TRIM10 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TRIM10 gene
    TRIM312  TRIM502  TRIM732  TRIM692  TRIM152  TRIM262  TRIM742  TRIM352  
    TRIM522  TRIM622  TRIM412  TRIM722  
    18 SIMAP similar genes for TRIM10 using alignment to 1 protein entry:     TRI10_HUMAN:
    TRIM15    ZNFB7    DKFZp686F23130    TRIM26    TRIM39    TRIM39R
    TRIM68    TRIM7    TRIM27    TRIM38    TRIM6    TRIM21
    TRIM60    TRIM69    TRIM75    TRIM11    TRIM41    TRIM58

    Find genes that share paralogs with TRIM10           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TRIM10 (see all 357)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs69054551,2
    C--30119263(+) GGTGAC/TCCCAC 2 -- int12Minor allele frequency- T:0.09WA 120
    rs92615261,2
    C,F,A,H--30119275(+) AACTCG/ACTCAC 2 -- int110Minor allele frequency- A:0.23NS EA NA CSA WA 781
    rs1181665441,2
    C,F--30119280(+) GCTCAC/TGCCTG 2 -- int11Minor allele frequency- T:0.11EA 120
    rs1932940311,2
    --30119281(+) CTCACA/GCCTGA 2 -- int10--------
    rs92615271,2
    C,F,A,H--30119392(+) TCTCAG/ATTCTT 2 -- int110Minor allele frequency- A:0.23NS EA NA CSA WA 784
    rs92615281,2
    C,F,A,H--30119429(+) AAGCTT/GTGAAA 2 -- int113Minor allele frequency- G:0.23NS EA NA CSA WA 922
    rs1430224901,2
    C--30119433(+) TTTGAA/TAAATG 2 -- int10--------
    rs1486674201,2
    --30119485(+) AGAGTC/TGGAAA 2 -- int10--------
    rs1855463881,2
    --30119486(+) GAGTCA/GGAAAG 2 -- int10--------
    rs1902574041,2
    --30119531(+) ACTTCC/TTGGGG 2 -- int10--------

    HapMap Linkage Disequilibrium report for TRIM10 (30119722 - 30128711 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for TRIM10:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2731777CNV Deletion23290073

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TRIM10
    DNA2.0 Custom Variant and Variant Library Synthesis for TRIM10

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 605701    OMIM disorders: --


    Find genes that share disorders with TRIM10           About GenesLikeMe

    Genetic Association Database (GAD): TRIM10
    Human Genome Epidemiology (HuGE) Navigator: TRIM10 (2 documents)

    Export disorders for TRIM10 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TRIM10 gene, integrated from 10 sources (see all 22):
    (articles sorted by number of sources associating them with TRIM10)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning, structural analysis, and mapping of the B30 and B7 multigenic families to the major histocompatibility complex (MHC) and other chromosomal regions. (PubMed id 9271628)1, 2, 3 Henry J.... Pontarotti P. (Immunogenetics 1997)
    2. Common genetic variation and the control of HIV-1 in humans. (PubMed id 20041166)1, 4 Fellay J....Goldstein D.B. (PLoS Genet. 2009)
    3. High-density SNP screening of the major histocompatibility complex in systemic lupus erythematosus demonstrates strong evidence for independent susceptibility regions. (PubMed id 19851445)1, 4 Barcellos L.F....Criswell L.A. (PLoS Genet. 2009)
    4. Rapid evolution of major histocompatibility complex class I genes in primates generates new disease alleles in humans via hitchhiking diversity. (PubMed id 16702430)1, 2 Shiina T.... Bahram S. (Genetics 2006)
    5. The tripartite motif family identifies cell compartments. (PubMed id 11331580)1, 2 Reymond A.... Ballabio A. (EMBO J. 2001)
    6. HERF1, a novel hematopoiesis-specific RING finger protein, is required for terminal differentiation of erythroid cells. (PubMed id 10207104)1, 3 Harada H....Downing J.R. (Mol. Cell. Biol. 1999)
    7. Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition. (PubMed id 22939624)1 Taipale M....Lindquist S. (Cell 2012)
    8. Functional interactions between ubiquitin E2 enzymes and TRIM proteins. (PubMed id 21143188)1 Napolitano L.M....Meroni G. (Biochem. J. 2011)
    9. Genome-wide association analysis of susceptibility and clinical phenotype in multiple sclerosis. (PubMed id 19010793)4 Baranzini S.E....Oksenberg J.R. (Hum. Mol. Genet. 2009)
    10. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10107 HGNC: 10072 AceView: TRIM10 Ensembl:ENSG00000204613 euGenes: HUgn10107
    ECgene: TRIM10 H-InvDB: TRIM10

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TRIM10 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TRIM10 gene:
    Search GeneIP for patents involving TRIM10

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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