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TRIAP1 Gene

protein-coding   GIFtS: 48
GCID: GC12M120881

TP53 Regulated Inhibitor Of Apoptosis 1

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
TP53 Regulated Inhibitor Of Apoptosis 11 2     P53CSV2
P53-Inducible Cell-Survival Factor1 2 3     Mitochondrial Distribution And Morphology 35 Homolog2
Protein 15E1.12 3     TP53-Regulated Inhibitor Of Apoptosis 12
WF-12 3     15E1.13
Mitochondrial Distribution And Morphology 35 Homolog (S. Cerevisiae)1     p53CSV3
MDM352     HSPC1325

External Ids:    HGNC: 269371   Entrez Gene: 514992   Ensembl: ENSG000001708557   OMIM: 6149435   UniProtKB: O437153   

Export aliases for TRIAP1 gene to outside databases

Previous GC identifers: GC12M119366 GC12M117891


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for TRIAP1 Gene:
TRIAP1 (TP53 regulated inhibitor of apoptosis 1) is a protein-coding gene. GO annotations related to this gene include cysteine-type endopeptidase inhibitor activity involved in apoptotic process.

UniProtKB/Swiss-Prot: TRIA1_HUMAN, O43715
Function: Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of
cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of
phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion
intermembrane space to provide PA for CL synthesis in the inner membrane. Mediates cell survival by inhibiting
activation of caspase-9 which prevents induction of apoptosis




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000012.11  NC_018923.2  NT_029419.13  
Regulatory elements:
   Regulatory transcription factor binding sites in the TRIAP1 gene promoter:
         GR   RFX1   GR-beta   MyoD   Olf-1   MIF-1   C/EBPalpha   Max   GR-alpha   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidTRIAP1 promoter sequence
   Search Chromatin IP Primers for TRIAP1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat TRIAP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q24.31   Ensembl cytogenetic band:  12q24.31   HGNC cytogenetic band: 12q24.31

TRIAP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TRIAP1 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M120881:  view genomic region     (about GC identifiers)

Start:
120,881,764 bp from pter      End:
120,884,215 bp from pter
Size:
2,452 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: TRIA1_HUMAN, O43715 (See protein sequence)
Recommended Name: TP53-regulated inhibitor of apoptosis 1  
Size: 76 amino acids; 8786 Da
Subunit: Interacts with APAF1 and HSP70. Forms a complex with PRELID1 in the mitochondrion intermembrane space
Sequence caution: Sequence=AAR00584.1; Type=Erroneous initiation;
Secondary accessions: B2R4Z7 Q5RKS5 Q6LCA7

Explore the universe of human proteins at neXtProt for TRIAP1: NX_O43715

Explore proteomics data for TRIAP1 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See TRIAP1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_057483.1  
    ENSEMBL proteins: 
     ENSP00000449795  

    TRIAP1 Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for TRIAP1

     
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    Search for Antibodies for TRIAP1 at Abcam
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    TRIAP1 Assay Products:

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    Cloud-Clone Corp. ELISAs for TRIAP1
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    Search eBioscience for ELISAs for TRIAP1 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR007918 MDM35_apoptosis

    Graphical View of Domain Structure for InterPro Entry O43715

    ProtoNet protein and cluster: O43715

    1 Blocks protein domain: IPB007918 Protein of unknown function UPF0203

    UniProtKB/Swiss-Prot: TRIA1_HUMAN, O43715
    Similarity: Belongs to the TRIAP1/MDM35 family


    Find genes that share domains with TRIAP1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: TRIA1_HUMAN, O43715
    Function: Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of
    cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of
    phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion
    intermembrane space to provide PA for CL synthesis in the inner membrane. Mediates cell survival by inhibiting
    activation of caspase-9 which prevents induction of apoptosis
    Induction: In p53/TP53-dependent manner in response to low levels of DNA damage. Not induced when DNA damage is
    severe

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0002039p53 binding IPI15735003
    GO:0005515protein binding IPI15735003
    GO:0043027cysteine-type endopeptidase inhibitor activity involved in apoptotic process ----
    GO:1990050contributes to phosphatidic acid transporter activity IDA--
         
    Find genes that share ontologies with TRIAP1           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for TRIAP1:
     Actin fiber cells 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for TRIAP1
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for TRIAP1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for TRIAP1

    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate TRIAP1 (see all 10):
    hsa-miR-4324 hsa-miR-320a hsa-miR-125a-5p hsa-miR-320d hsa-miR-103a hsa-miR-320b hsa-miR-125b hsa-miR-378*
    SwitchGear 3'UTR luciferase reporter plasmidTRIAP1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TRIAP1

    Gene Editing
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    Browse Sino Biological Human cDNA Clones
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIAP1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    TRIA1_HUMAN, O43715: Cytoplasm, perinuclear region. Mitochondrion. Mitochondrion intermembrane space
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion4
    cytosol3
    extracellular3
    nucleus3
    plasma membrane1

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IDA15735003
    GO:0005758mitochondrial intermembrane space IDA--
    GO:0043234protein complex IDA--
    GO:0048471perinuclear region of cytoplasm IEA--

    Find genes that share ontologies with TRIAP1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for TRIAP1 About    
    See pathways by source

    SuperPathContained pathways About
    1Direct p53 effectors
    Direct p53 effectors


    1 BioSystems Pathway for TRIAP1
        Direct p53 effectors


        Pathway & Disease-focused RT2 Profiler PCR Array including TRIAP1: 
              Apoptosis 384HT in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for TRIAP1

    Selected Interacting proteins for TRIAP1 (O437153) via UniProtKB, MINT, STRING, and/or I2D (see all 12)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000212866P081073I2D: score=1 
    ENSG00000215328P081073I2D: score=1 
    ENSG00000224501P081073I2D: score=1 
    ENSG00000231555P081073I2D: score=1 
    ENSG00000232804P081073I2D: score=1 
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    Gene Ontology (GO): Selected biological process terms (see all 11):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006977DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest TAS15735003
    GO:0015914phospholipid transport IDA--
    GO:0030330DNA damage response, signal transduction by p53 class mediator IDA15735003
    GO:0034644cellular response to UV IDA15735003
    GO:0043066negative regulation of apoptotic process IMP--

    Find genes that share ontologies with TRIAP1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for TRIAP1 (TRIA1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for TRIAP1 gene: 
    NM_016399.2  

    Unigene Cluster for TRIAP1:

    TP53 regulated inhibitor of apoptosis 1
    Hs.69499  [show with all ESTs]
    Unigene Representative Sequence: BM910747
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000546954(uc001tyg.3) ENST00000302432
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate TRIAP1 (see all 10):
    hsa-miR-4324 hsa-miR-320a hsa-miR-125a-5p hsa-miR-320d hsa-miR-103a hsa-miR-320b hsa-miR-125b hsa-miR-378*
    SwitchGear 3'UTR luciferase reporter plasmidTRIAP1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat TRIAP1
    Clone
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    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: TRIAP1 (NM_016399)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for TRIAP1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TRIAP1
    Primer
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    OriGene qPCR primer pairs and template standards for TRIAP1
    OriGene qSTAR qPCR primer pairs in human, mouse for TRIAP1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat TRIAP1
      QuantiTect SYBR Green Assays in human, mouse, rat TRIAP1
      QuantiFast Probe-based Assays in human, mouse, rat TRIAP1

    Additional mRNA sequence: 

    AF161481.1 AK312006.1 BC002638.2 BC055313.1 U75688.1 

    6 DOTS entries:

    DT.412908  DT.95275447  DT.100863697  DT.92438289  DT.92438291  DT.97843950 

    Selected AceView cDNA sequences (see all 229):

    BU175259 NM_016399 BQ071011 BU192226 BQ775340 BC002638 BQ954589 BF684139 
    BM794287 BE394127 BM452278 CR598391 BQ919365 AA369283 BQ962184 BF683935 
    CN479468 BE858411 CA313634 BU845708 BQ070872 BE747267 BU848872 AI458093 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    TRIAP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCAAAGAAAA
    TRIAP1 Expression
    About this image

    TRIAP1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    TRIAP1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.69499
        Pathway & Disease-focused RT2 Profiler PCR Array including TRIAP1: 
              Apoptosis 384HT in human mouse rat

    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRIAP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for TRIAP1 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Triap11 , 5 TP53 regulated inhibitor of apoptosis 11, 5 92.11(n)1
    98.68(a)1
      5 (56.06 cM)5
    690761  NM_026933.21  NP_081209.11 
     1153412255 
    chicken
    (Gallus gallus)
    Aves TRIAP11 TP53 regulated inhibitor of apoptosis 1 83.33(n)
    82.89(a)
      416977  NM_001277508.1  NP_001264437.1 
    lizard
    (Anolis carolinensis)
    Reptilia TRIAP16
    TP53 regulated inhibitor of apoptosis 1
    81(a)
    1 ↔ 1
    GL343338.1(71804-72517)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.202012 Xenopus laevis transcribed sequence with moderate similarity more 77.38(n)    BG552101.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.178762 Transcribed sequence with moderate similarity to protein more 79.9(n)    57061833 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG301086
    CG301096
    --
    39(a)
    36(a)
    many → 1
    many → 1
    2R(13556905-13557505)
    2R(13556910-13558253)


    ENSEMBL Gene Tree for TRIAP1 (if available)
    TreeFam Gene Tree for TRIAP1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for TRIAP1 gene

    Find genes that share paralogs with TRIAP1           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for TRIAP1
    PGOHUM00000238381 PGOHUM00000260622


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for TRIAP1 (see all 13)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs11518451,2
    C,F,O,A,H--120881288(+) GTACCA/GTAGTG 1 -- int129Minor allele frequency- G:0.23NS EA NA WA CSA 2656
    rs1857434191,2
    --120881329(+) AAATCA/TGTGAG 1 -- int10--------
    rs1161226321,2
    C,F--120881348(+) TGGGTG/TCGGTG 1 -- int11Minor allele frequency- T:0.03WA 118
    rs1132789021,2
    C--120881591(+) GTCTC-/AAAAAA 1 -- int11Minor allele frequency- A:0.50CSA 2
    rs1468321631,2
    --120881621(+) ATTGCC/TATACT 1 -- int10--------
    rs1392192131,2
    C--120881764(+) GCAAAC/TAATGA 1 -- ut310--------
    rs38093091,2
    C,H--120881917(-) TGCATA/TTCCTA 1 -- ut31 ese34Minor allele frequency- T:0.00NS EA 416
    rs1175196881,2
    C,F--120881931(+) TGACAA/GTTCAC 1 -- ut311Minor allele frequency- G:0.02NA 120
    rs1900645041,2
    --120882122(+) TAAAAA/GCTGTC 1 -- ut310--------
    rs10488301,2
    C,F,A,H--120882217(-) CACAAC/AAGTTT 1 -- ut3115Minor allele frequency- A:0.35MN NA WA CSA EA 702

    HapMap Linkage Disequilibrium report for TRIAP1 (120881764 - 120884215 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for TRIAP1:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv509482CNV Insertion20534489
    nsv819389CNV Loss19587683

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing TRIAP1
    DNA2.0 Custom Variant and Variant Library Synthesis for TRIAP1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 614943    OMIM disorders: --

    4 diseases from the University of Copenhagen DISEASES database for TRIAP1:
    Lupus erythematosus     Nephritis     Connective tissue disease     Proteinuria

    Find genes that share disorders with TRIAP1           About GenesLikeMe

    Genetic Association Database (GAD): TRIAP1
    Human Genome Epidemiology (HuGE) Navigator: TRIAP1 (1 document)

    Export disorders for TRIAP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for TRIAP1 gene, integrated from 10 sources (see all 19):
    (articles sorted by number of sources associating them with TRIAP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. p53CSV, a novel p53-inducible gene involved in the p53-dependent cell-survival pathway. (PubMed id 15735003)1, 2, 3, 9 Park W.-R. and Nakamura Y. (Cancer Res. 2005)
    2. Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells. (PubMed id 11042152)1, 2, 3 Zhang Q.-H.... Chen Z. (Genome Res. 2000)
    3. Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (PLoS ONE 2010)
    4. The finished DNA sequence of human chromosome 12. (PubMed id 16541075)1, 2 Scherer S.E.... Gibbs R.A. (Nature 2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. A genetic screen identifies TCF3/E2A and TRIAP1 as pathway-specific regulators of the cellular response to p53 activation. (PubMed id 23684607)1 Andrysik Z....Espinosa J.M. (Cell Rep 2013)
    7. TRIAP1/PRELI complexes prevent apoptosis by mediating intramitochondrial transport of phosphatidic acid. (PubMed id 23931759)2 Potting C....Langer T. (Cell Metab. 2013)
    8. Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity. (PubMed id 23824909)1 Chen Y....Ge F. (amp 2013)
    9. N-terminal acetylome analyses and functional insights of the N- terminal acetyltransferase NatB. (PubMed id 22814378)2 Van Damme P....Aldabe R. (Proc. Natl. Acad. Sci. U.S.A. 2012)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 51499 HGNC: 26937 AceView: HSPC132 Ensembl:ENSG00000170855 euGenes: HUgn51499
    ECgene: TRIAP1 H-InvDB: TRIAP1

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for TRIAP1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for TRIAP1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for TRIAP1 gene:
    Search GeneIP for patents involving TRIAP1

    GeneCards and IP:
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