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TRGV5 Gene(Protein Coding)

T Cell Receptor Gamma Variable 5

GCID:
GC07M038497
GIFtS:
17
Genes Participants
UDN Logo

Aliases for TRGV5 Gene

Aliases for TRGV5 Gene

  • T Cell Receptor Gamma Variable 5 2 3 5
  • T-Cell Receptor, Gamma, Variable Region V5 2 3
  • T-Cell Gamma Precursor Protein 3
  • TCRGV5 3
  • V1S5 3

External Ids for TRGV5 Gene

Previous HGNC Symbols for TRGV5 Gene

  • TCRGV5

Previous GeneCards Identifiers for TRGV5 Gene

  • GC07U990109
  • GC07M038095
  • GC07M038129
  • GC07M038162
  • GC07M038351
  • GC07M038388
  • GC07M038426
  • GC07M038451
  • GC07M038459
  • GC07M038473
  • GC07M038485

Summaries for TRGV5 Gene

GeneCards Summary for TRGV5 Gene

TRGV5 (T Cell Receptor Gamma Variable 5) is a Protein Coding gene. An important paralog of this gene is TRGV3.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRGV5 Gene

Genomics for TRGV5 Gene

Products:

  1. Regulatory Element

Regulatory Elements for TRGV5 Gene

Enhancers for TRGV5 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07F038334 1.3 FANTOM5 ENCODE 13.3 +13.7 13682 3.7 HDGF ATF1 PKNOX1 ARNT CREB3L1 ZNF48 ZNF2 ZNF143 ZNF263 SP3 ENSG00000272908 TRGV5 TRGV5P STARD3NL AMPH TRGV6 TRGV7
GH07F038393 0.8 FANTOM5 Ensembl 13.6 -44.6 -44616 1.7 CTCF PBX2 RAD21 AMPH TRGV5 STARD3NL TARP TRGV1 RN7SL83P
GH07F038358 0.7 ENCODE 12.1 -9.2 -9179 2.2 ZNF263 CTCF ATF1 ZNF654 TRIM22 NFXL1 REST RAD21 IKZF1 ZNF143 TRGV4 TRGV5P TRGV5 TRGV3 AMPH GC07P038360
GH07F038307 1.5 FANTOM5 Ensembl ENCODE 5.1 +40.2 40219 4.4 HDGF TBP HDAC1 ATF1 CREB3L1 NFRKB NFXL1 ZBTB40 YY1 GLIS2 TRGV9 STARD3NL TRGV5 TARP LOC103689914
GH07F038303 1 Ensembl ENCODE 5.2 +44.4 44390 3.4 CTCF ZNF384 ZBTB40 RAD21 ZNF366 ZBTB48 EED ZNF143 ZNF263 SP3 ENSG00000272908 TRGV5P TRGV4 TRGV5 TRGV9 TRGV3 TARP TRGV10
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TRGV5 on UCSC Golden Path with GeneCards custom track

Promoters for TRGV5 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001891056 -278 2201 ZNF263 CTCF MAX NFXL1 RAD21 IKZF1 NBN ZNF143 MYC SPI1
ENSR00001713010 -1678 201

Genomic Location for TRGV5 Gene

Chromosome:
7
Start:
38,349,355 bp from pter
End:
38,350,022 bp from pter
Size:
668 bases
Orientation:
Minus strand

Genomic View for TRGV5 Gene

Genes around TRGV5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRGV5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRGV5 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for TRGV5 Gene

Proteins for TRGV5 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

  • Protein details for TRGV5 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A0B4J1U4
    Recommended name:
    Protein TRGV5
    Protein Accession:
    A0A0B4J1U4

    Protein attributes for TRGV5 Gene

    Size:
    118 amino acids
    Molecular mass:
    13601 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRGV5 Gene

Post-translational modifications for TRGV5 Gene

No Post-translational modifications

Other Protein References for TRGV5 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRGV5 Gene

Domains & Families for TRGV5 Gene

Gene Families for TRGV5 Gene

HGNC:

Protein Domains for TRGV5 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRGV5: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TRGV5 Gene

Function for TRGV5 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line
  7. Flow Cytometry

Animal Model Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRGV5 Gene

Localization for TRGV5 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TRGV5 Gene

Pathways & Interactions for TRGV5 Gene

SuperPathways for TRGV5 Gene

PathCards logo More details on SuperPathways for TRGV5
No Data Available

Interacting Proteins for TRGV5 Gene

Gene Ontology (GO) - Biological Process for TRGV5 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TRGV5 Gene

Drugs & Compounds for TRGV5 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for TRGV5 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone
  5. Flow Cytometry

mRNA/cDNA for TRGV5 Gene

(359) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRGV5 Gene

No ASD Table

Relevant External Links for TRGV5 Gene

GeneLoc Exon Structure for
TRGV5
ECgene alternative splicing isoforms for
TRGV5

Expression for TRGV5 Gene

Products:

  1. Primer

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TRGV5 Gene

mRNA expression in normal human tissues for TRGV5 Gene
mRNA expression by GTEx for TRGV5 Gene

mRNA differential expression in normal tissues according to GTEx for TRGV5 Gene

This gene is overexpressed in Whole Blood (x12.1) and Spleen (x5.4).

NURSA nuclear receptor signaling pathways regulating expression of TRGV5 Gene:

TRGV5
genes like me logo Genes that share expression patterns with TRGV5: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for TRGV5 Gene

Orthologs for TRGV5 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TRGV5 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
 Mammalia -- 35
  • 53 (a)
 OneToMany
platypus
(Ornithorhynchus anatinus)
 Mammalia -- 35
  • 41 (a)
 ManyToMany
-- 35
  • 40 (a)
 ManyToMany
-- 35
  • 39 (a)
 ManyToMany
-- 35
  • 36 (a)
 ManyToMany
-- 35
  • 34 (a)
 ManyToMany
-- 35
  • 32 (a)
 ManyToMany
-- 35
  • 31 (a)
 ManyToMany
-- 35
  • 24 (a)
 ManyToMany
Species where no ortholog for TRGV5 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TRGV5 Gene

ENSEMBL:
Gene Tree for TRGV5 (if available)
TreeFam:
Gene Tree for TRGV5 (if available)

Paralogs for TRGV5 Gene

Paralogs for TRGV5 Gene

genes like me logo Genes that share paralogs with TRGV5: view

Variants for TRGV5 Gene

Relevant External Links for TRGV5 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRGV5

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRGV5 Gene

Disorders for TRGV5 Gene

Relevant External Links for TRGV5

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TRGV5

No disorders were found for TRGV5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TRGV5 Gene

Publications for TRGV5 Gene

  1. The V gamma locus of the human T cell receptor gamma gene. Repertoire polymorphism of the first variable gene segment subgroup. (PMID: 2902186) Font M.P. … Sigaux F. (J. Exp. Med. 1988) 2 3 64
  2. Variable region genes in the human T-cell rearranging gamma (TRG) locus: V-J junction and homology with the mouse genes. (PMID: 2969332) Huck S. … Lefranc M.P. (EMBO J. 1988) 2 3 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64
  4. The human T-cell receptor gamma (TRG) genes. (PMID: 2527426) Lefranc M.P. … Rabbitts T.H. (Trends Biochem. Sci. 1989) 3 64
  5. Structure of the gamma/delta T cell receptor of a human thymocyte clone. (PMID: 2844954) Okada A. … Alt F.W. (J. Exp. Med. 1988) 3 64

Products for TRGV5 Gene

Sources for TRGV5 Gene

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