TRGV5 Gene protein-coding GIFtS : 21 GCID: GC07 M038388
T Cell Receptor Gamma Variable 5 TCRGV5 )
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Aliasesfor TRGV5 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
10 fRNAdb ,
12 H-InvDB ,
13 NCBI ,
14 NONCODE ,
and/or 15 RNAdb )About This Section GeneCards Plus Aliases T Cell Receptor Gamma Variable 5 1 2 TCRGV51 2 gamma1 T-Cell Receptor1 Variable Region V51 V1S52
Export aliases for TRGV5 gene to outside databases Previous GC identifers: GC07U990109 GC07M038095 GC07M038129 GC07M038162 GC07M038351 GC07M038426
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Summariesfor TRGV5 gene (According to Entrez Gene ,
GeneCards ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section GeneCards Plus GeneCards Summary for TRGV5 Gene: TRGV5 (T cell receptor gamma variable 5) is a protein-coding gene. An important paralog of this gene is TRGV1 .
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Genomic Viewsfor TRGV5 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,miRBase ,UCSC (hg19) and
Ensembl (release 75) ,
Regulatory elements and Epigenetics data according to
QIAGEN , and/or
SwitchGear Genomics )About This Section GeneCards Plus Regulatory elements: Search for regulatory transcription factor binding sites for TRGV5 Other transcription factors Search Chromatin IP Primers for TRGV5 Epigenetics: DNA Methylation CpG Assay Predesigned for Pyrosequencing in human mouse rat
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 7p14 Ensembl cytogenetic band: 7p14.1 HGNC cytogenetic band: 7p14 TRGV5 Gene in genomic location: bands according to Ensembl, locations according to
Entrez Gene Ensembl GeneLoc information about chromosome 7 GeneLoc Exon Structure
GeneLoc location for GC07M038388: view genomic region
(about GC identifiers )
Start: 38,388,956 bp from pter End:
38,389,623 bp from pter
Size: 668 bases Orientation:
minus strand
1 alternative location : Chr 7-,CRA_TCAG 38,426,627-38,427,096
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Proteinsfor TRGV5 gene
(According to
1 UniProtKB ,
HORDE ,
2 neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to PhosphoSitePlus ,
Specific Peptides from DME ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Cloud-Clone Corp. ,
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Cloud-Clone Corp. ,
Antibodies by
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
LSBio ,
Abcam , and/or
Cloud-Clone Corp. )
About This Section GeneCards Plus UniProtKB/TrEMBL: A2NUW5 See
protein sequence )Recommended Name: Size : 133 amino acids; 15177 Da1 PDB 3D structure from :4NDM (3D) Explore proteomics data for TRGV5 at MOPED See TRGV5 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB
ENSEMBL proteins: ENSP00000374867 TRGV5 Human Recombinant
Protein Products: TRGV5 Antibody
Products: TRGV5 Assay Products:
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Domains /for TRGV5 gene (According to HGNC , IUPHAR , InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section GeneCards Plus HGNC Gene Families: TRG: T cell receptors / TRG locus 3 InterPro protein domains :
Graphical View of Domain Structure for InterPro Entry A2NUW5 ProtoNet protein and cluster: A2NUW5
About GeneDecksing
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Functionfor TRGV5 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
genOway ,
QIAGEN
and/or HOMER ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
SwitchGear Genomics ,
Gene Editing from DNA2.0 ,
Clones from OriGene ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
ESI BIO ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene .)
About This Section GeneCards Plus Gene Ontology (GO): 1 molecular function term : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0005515 protein binding
-- --
About GeneDecksing Animal Models: Inhib. RNA Browse OriGene RNAi Predesigned siRNA for gene silencing in human mouse rat
Cell Line GenScript Custom overexpressing Cell Line Services for TRGV5 Browse ESI BIO Cell Lines and PureStem Progenitors for TRGV5 In Situ AssayAdvanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRGV5
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Localizationfor TRGV5 gene
(According to UniProtKB , COMPARTMENTS Subcellular localization database ,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene .)
About This Section GeneCards Plus Subcellular locations from COMPARTMENTS : Compartment Confidence extracellular 3
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Pathways & Interactionsfor TRGV5 gene
(SuperPaths according to PathCards ,
Pathways according to
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Sino Biological ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
QIAGEN ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene) .
About This Section GeneCards Plus Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TRGV5 Interactions: Search GeneGlobe Interaction Network for TRGV5
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Drugs & Compoundsfor TRGV5 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience ,
ApexBio ,
HMDB ,
BitterDB , and/or
Novoseek ,
Ligands according to IUPHAR ,
and Drugs according to DrugBank ,
Enzo Life Sciences , and/or
PharmGKB )
About This Section GeneCards Plus Browse compounds at ApexBio Browse Tocris compounds for TRGV5
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Transcriptsfor TRGV5 gene (Secondary structures according to
fRNAdb ,Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank , Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC , KenesGroup ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
SwitchGear Genomics ,
OriGene ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene , and/or
QIAGEN
)About This Section GeneCards Plus 1 Ensembl transcript including schematic representation, and UCSC links where relevant : ENST00000390344 (uc022aca.1 ) Inhib. RNA Browse OriGene RNAi Predesigned siRNA for gene silencing in human mouse rat
Selected AceView cDNA sequences (see all 359 ):
NM_001003806 BX281781 NM_001003799 BM478583 CR605178 BQ002856 R33649 AW575113 AI823897 AV715641 BV205017 BM922364 BF109398 BC062761 BF674593 BX504327 AV714756 BV205007 AI768834 AL559196 AV714189 BV205029 BC039725 R70639 GeneLoc Exon Structure
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Expression for TRGV5 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
Protein expression images according to data from SPIRE 1 MOPED ,
2 PaxDb , and 3 MaxQB ,
plus additional links to
SOURCE , and/or
BioGPS , and/or
UniProtKB ,QIAGEN ,
Primers from
OriGene , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section GeneCards Plus TRGV5 expression in normal human tissues
(normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS 2/3 CGAP TAG: -- About this image
TRGV5 Protein expression data from MOPED1 2 3 : About this image Custom PCR Arrays for TRGV5 Primer Browse OriGene qPCR Search Pre-validated RT2 qPCR
Primer Assays in human, mouse, rat TRGV5 QuantiTect SYBR Green Assays in human mouse rat QuantiFast Probe-based Assays in human mouse rat In Situ Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRGV5
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Orthologsfor TRGV5 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section GeneCards Plus Orthologs for TRGV5 gene from Selected species (see all 2 ) About this table
ENSEMBL Gene Tree for TRGV5 (if available)TreeFam Gene Tree for TRGV5 (if available)
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Paralogsfor TRGV5 gene (Paralogs according to
1 HomoloGene ,2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section GeneCards Plus Paralogs for TRGV5 gene TRGV1 2 TRGV3 2 TRGV8 2 TRGV4 2 TRGV2 2 About GeneDecksing
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Genomic Variantsfor TRGV5 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
4 UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) , the Human Cytochrome P450 Allele
Nomenclature Database , and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN )
About This Section GeneCards Plus Site Specific Mutation Identification with PCR Assays
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Disorders
/ Diseasesfor TRGV5 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database , Conferences by KenesGroup ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section GeneCards Plus
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Publicationsfor TRGV5 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section GeneCards Plus PubMed articles for TRGV5 gene integrated from 10 sources :(articles sorted by number of sources associating them with TRGV5) Utopia : connect your pdf to the dynamic
The V gamma locus of the human T cell receptor gamma gene. Repertoire polymorphism of the first variable gene segment subgroup. (PubMed id 2902186) 1 , 3(J. Exp. Med. 1988) Variable region genes in the human T-cell rearranging gamma (TRG) locus: V-J junction and homology with the mouse genes. (PubMed id 2969332) 1 , 3(EMBO J. 1988) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 (Proc. Natl. Acad. Sci. U.S.A. 2002) The human T-cell receptor gamma (TRG) genes. (PubMed id 2527426) 1 (Trends Biochem. Sci. 1989) Structure of the gamma/delta T cell receptor of a human thymocyte clone. (PubMed id 2844954) 1 (J. Exp. Med. 1988)
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External Searches for TRGV5 gene (in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section GeneCards Plus
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Genome Databases showing TRGV5 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section GeneCards Plus
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Other Databases showing TRGV5 gene
(According to HUGE )
About This Section GeneCards Plus --
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Specialized Databases showing TRGV5 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , UniProtKB/TrEMBL , and/or others, e.g. Wikipedia and GeneReviews , via UniProtKB/Swiss-Prot )About This Section GeneCards Plus
Name Description PharmGKB entry for TRGV5 Pharmacogenomics, SNPs, Pathways IMGT entry for TRGV5The international I mM unoG eneT ics information system® specializing in Immunoglobulins (IG), T cell receptors (TR), Major Histocompatibility Complex (MHC) and related proteins of the immune system (RPI) of human and other vertebrate species.
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About This Section GeneCards Plus Patent Information for TRGV5 gene: TRGV5 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor TRGV5 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Cloud-Clone Corp. , Thermo Fisher Scientific , LSBio , Gene Editing from DNA2.0 . Clones from OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , and ESI BIO , PCR Arrays from QIAGEN , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , Enzo Life Sciences , and/or
ApexBio , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory ,
genOway )About This Section GeneCards Plus
Block miRNA regulation of human, mouse, rat TRGV5 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing TRGV5 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human mouse rat Predesigned siRNA for gene silencing in human mouse rat QuantiFast Probe-based Assays in human mouse rat QuantiTect SYBR Green Assays in human mouse rat Custom PCR Arrays for TRGV5 Search Chromatin IP Primers for TRGV5 Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat TRGV5 Search GeneGlobe Interaction Network for TRGV5 Search Regulatory tfbs for TRGV5
Search Tocris compounds for TRGV5
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRGV5
Search ThermoFisher Antibodies for TRGV5
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TRGV5
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Genomic Views for TRGV5
Intellectual Property for TRGV5
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