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Aliases for TRGV4 Gene

Aliases for TRGV4 Gene

  • T Cell Receptor Gamma Variable 4 2 3 5
  • T-Cell Receptor, Gamma, Variable Region V4 2 3
  • TCRGV4 3
  • V1S4 3

External Ids for TRGV4 Gene

Previous HGNC Symbols for TRGV4 Gene

  • TCRGV4

Previous GeneCards Identifiers for TRGV4 Gene

  • GC07U990108
  • GC07M038100
  • GC07M038134
  • GC07M038166
  • GC07M038359
  • GC07M038394
  • GC07M038430
  • GC07M038397
  • GC07M038400
  • GC07M038428
  • GC07M038675
  • GC07M038903
  • GC07M039132
  • GC07M039263
  • GC07M038435
  • GC07M038461
  • GC07M038475
  • GC07M038487

Summaries for TRGV4 Gene

GeneCards Summary for TRGV4 Gene

TRGV4 (T Cell Receptor Gamma Variable 4) is a Protein Coding gene. An important paralog of this gene is TRGV2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRGV4 Gene

Genomics for TRGV4 Gene

Regulatory Elements for TRGV4 Gene

Enhancers for TRGV4 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07F038366 1 Ensembl ENCODE 52.9 -14.2 -14228 4.2 HDGF CTCF WRNIP1 NFXL1 YBX1 EBF1 RAD21 EED ZNF143 SMC3 TRGV4 TRGV5P TRGV3 AMPH TRGV1 RN7SL83P
GH07F038339 1 ENCODE 32 +13.3 13290 2.6 HDGF ATF1 PKNOX1 ARNT CREB3L1 KLF13 ZNF263 NCOA1 REST SMARCA4 TRGV4 TRGV3 TRGV5P TRG-AS1 TRGV6
GH07F038362 0.7 ENCODE 45.2 -8.7 -8682 2.0 ZNF263 CTCF ZNF146 MTA2 TRIM22 NFXL1 EBF1 RAD21 ZNF366 IKZF1 TRGV4 TRGV5P TRGV3 GC07P038360 TRGV2
GH07F038358 0.7 ENCODE 43.9 -4.7 -4684 2.2 ZNF263 CTCF ATF1 ZNF654 TRIM22 NFXL1 REST RAD21 IKZF1 ZNF143 TRGV4 TRGV5P TRGV5 TRGV3 AMPH GC07P038360
GH07F038344 0.7 ENCODE 43.2 +9.3 9336 2.3 HDGF ZNF263 CTCF ZNF654 SP3 TRIM22 RAD21 ZBTB48 ZNF366 IKZF1 TRGV4 TRGV5P TRGV3 AMPH TRGV6 TRG-AS1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TRGV4 on UCSC Golden Path with GeneCards custom track

Genomic Location for TRGV4 Gene

Chromosome:
7
Start:
38,353,715 bp from pter
End:
38,354,517 bp from pter
Size:
803 bases
Orientation:
Minus strand

Genomic View for TRGV4 Gene

Genes around TRGV4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRGV4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRGV4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRGV4 Gene

Proteins for TRGV4 Gene

  • Protein details for TRGV4 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A0C4DH28
    Recommended name:
    Protein TRGV4
    Protein Accession:
    A0A0C4DH28

    Protein attributes for TRGV4 Gene

    Size:
    118 amino acids
    Molecular mass:
    13152 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRGV4 Gene

Post-translational modifications for TRGV4 Gene

No Post-translational modifications

Other Protein References for TRGV4 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRGV4 Gene

Domains & Families for TRGV4 Gene

Gene Families for TRGV4 Gene

Protein Domains for TRGV4 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRGV4: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TRGV4 Gene

Function for TRGV4 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRGV4 Gene

Localization for TRGV4 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TRGV4 Gene

Pathways & Interactions for TRGV4 Gene

SuperPathways for TRGV4 Gene

No Data Available

Interacting Proteins for TRGV4 Gene

Gene Ontology (GO) - Biological Process for TRGV4 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TRGV4 Gene

Transcripts for TRGV4 Gene

mRNA/cDNA for TRGV4 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for TRGV4 Gene

No ASD Table

Relevant External Links for TRGV4 Gene

GeneLoc Exon Structure for
TRGV4
ECgene alternative splicing isoforms for
TRGV4

Expression for TRGV4 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TRGV4 Gene

mRNA differential expression in normal tissues according to GTEx for TRGV4 Gene

This gene is overexpressed in Whole Blood (x12.0) and Spleen (x8.4).

NURSA nuclear receptor signaling pathways regulating expression of TRGV4 Gene:

TRGV4
genes like me logo Genes that share expression patterns with TRGV4: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for TRGV4 Gene

Orthologs for TRGV4 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TRGV4 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia -- 35
  • 54 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 41 (a)
ManyToMany
-- 35
  • 40 (a)
ManyToMany
-- 35
  • 40 (a)
ManyToMany
-- 35
  • 35 (a)
ManyToMany
-- 35
  • 35 (a)
ManyToMany
-- 35
  • 34 (a)
ManyToMany
-- 35
  • 32 (a)
ManyToMany
-- 35
  • 23 (a)
ManyToMany
Species where no ortholog for TRGV4 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TRGV4 Gene

ENSEMBL:
Gene Tree for TRGV4 (if available)
TreeFam:
Gene Tree for TRGV4 (if available)

Paralogs for TRGV4 Gene

Paralogs for TRGV4 Gene

genes like me logo Genes that share paralogs with TRGV4: view

Variants for TRGV4 Gene

Relevant External Links for TRGV4 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRGV4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRGV4 Gene

Disorders for TRGV4 Gene

No disorders were found for TRGV4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for TRGV4 Gene

Publications for TRGV4 Gene

  1. Variable region genes in the human T-cell rearranging gamma (TRG) locus: V-J junction and homology with the mouse genes. (PMID: 2969332) Huck S. … Lefranc M.P. (EMBO J. 1988) 2 3 64
  2. The human T-cell receptor gamma (TRG) genes. (PMID: 2527426) Lefranc M.P. … Rabbitts T.H. (Trends Biochem. Sci. 1989) 3 64

Products for TRGV4 Gene

Sources for TRGV4 Gene

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