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Aliases for TRGV3 Gene

Aliases for TRGV3 Gene

  • T Cell Receptor Gamma Variable 3 2 3
  • TCRGV3 2 3 4
  • T-Cell Receptor, Gamma, Variable Region V3 2 3
  • T-Cell Receptor Gamma V-Gamma-1.1 Region 4
  • T-Cell Receptor Gamma Variable 3 5
  • TCRB 4
  • V1S3 3

External Ids for TRGV3 Gene

Previous HGNC Symbols for TRGV3 Gene

  • TCRGV3

Previous GeneCards Identifiers for TRGV3 Gene

  • GC07U990107
  • GC07M038104
  • GC07M038138
  • GC07M038171
  • GC07M038364
  • GC07M038398
  • GC07M038283
  • GC07M038441
  • GC07M038463
  • GC07M038477
  • GC07M038489
  • GC07M038502
  • GC07M038515
  • GC07M038527

Summaries for TRGV3 Gene

GeneCards Summary for TRGV3 Gene

TRGV3 (T Cell Receptor Gamma Variable 3) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include peptide antigen binding and MHC protein binding. An important paralog of this gene is TRGV5.

Additional gene information for TRGV3 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRGV3 Gene

Genomics for TRGV3 Gene

GeneHancer (GH) Regulatory Elements for TRGV3 Gene

Promoters and enhancers for TRGV3 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07I038357 Enhancer 1.1 Ensembl ENCODE dbSUPER 559.8 -0.5 -539 3.8 CTCF RB1 BACH1 NFXL1 CC2D1A CTBP1 ZBTB48 EGR1 ZNF143 ZNF444 TRGV3 GC07P038357 GC07P038360 TRGV4 TRGV5P TRGV5 AMPH TRGV7 TRG TRG-AS1
GH07I038340 Enhancer 1.3 Ensembl ENCODE dbSUPER 10.3 +17.6 17591 3.3 HDGF PKNOX1 ATF1 ARNT POLR2B E2F8 ARID2 ATF7 ZNF263 NCOA1 TRG-AS1 TRGV6 TRGV4 TRGV3 TRGV5P TRG
GH07I038366 Enhancer 1.2 Ensembl ENCODE dbSUPER 9.4 -9.6 -9582 4.2 HDGF RB1 NFXL1 YBX1 IRF4 RAD21 ZNF143 ATF7 BCLAF1 IKZF2 TRG TRGV1 TRGV4 TRGV5P TRGV3 AMPH TRG-AS1 RN7SL83P
GH07I037443 Promoter/Enhancer 2.6 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 4.2 +912.3 912259 6.2 HDGF SIN3A FEZF1 ZNF2 IRF4 ZNF48 ETS1 GLIS2 ATF7 RUNX3 ELMO1 GPR141 RNU6-565P EPDR1 TRGV3 ENSG00000201566
GH07I038362 Enhancer 1 Ensembl ENCODE dbSUPER 10.1 -4.0 -4033 2 SMARCA5 CTCF ZNF146 RB1 TRIM22 NFXL1 RAD21 ZNF366 POLR2A IKZF1 GC07P038364 TRGV2 TRGV4 TRGV5P TRGV3 GC07P038360 TRG TRG-AS1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around TRGV3 on UCSC Golden Path with GeneCards custom track

Genomic Locations for TRGV3 Gene

Genomic Locations for TRGV3 Gene
chr7:38,358,512-38,359,162
(GRCh38/hg38)
Size:
651 bases
Orientation:
Minus strand
chr7:38,398,113-38,398,763
(GRCh37/hg19)

Genomic View for TRGV3 Gene

Genes around TRGV3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRGV3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRGV3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRGV3 Gene

Proteins for TRGV3 Gene

  • Protein details for TRGV3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P03979-TRGV3_HUMAN
    Recommended name:
    T cell receptor gamma variable 3
    Protein Accession:
    P03979
    Secondary Accessions:
    • A0A075B6L3

    Protein attributes for TRGV3 Gene

    Size:
    118 amino acids
    Molecular mass:
    13664 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRGV3 Gene

Post-translational modifications for TRGV3 Gene

No Post-translational modifications

Other Protein References for TRGV3 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRGV3 Gene

Domains & Families for TRGV3 Gene

Gene Families for TRGV3 Gene

Suggested Antigen Peptide Sequences for TRGV3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRGV3: view

No data available for UniProtKB/Swiss-Prot for TRGV3 Gene

Function for TRGV3 Gene

Phenotypes From GWAS Catalog for TRGV3 Gene

Gene Ontology (GO) - Molecular Function for TRGV3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0042287 MHC protein binding NAS 3458221
GO:0042605 peptide antigen binding NAS 3458221
genes like me logo Genes that share ontologies with TRGV3: view

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRGV3 Gene

Localization for TRGV3 Gene

Gene Ontology (GO) - Cellular Components for TRGV3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane NAS 3458221
genes like me logo Genes that share ontologies with TRGV3: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for TRGV3 Gene

Pathways & Interactions for TRGV3 Gene

SuperPathways for TRGV3 Gene

No Data Available

Interacting Proteins for TRGV3 Gene

Gene Ontology (GO) - Biological Process for TRGV3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006955 immune response NAS 3458221
genes like me logo Genes that share ontologies with TRGV3: view

No data available for Pathways by source and SIGNOR curated interactions for TRGV3 Gene

Drugs & Compounds for TRGV3 Gene

No Compound Related Data Available

Transcripts for TRGV3 Gene

mRNA/cDNA for TRGV3 Gene

(1) REFSEQ mRNAs :
(5) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for TRGV3 Gene

No ASD Table

Relevant External Links for TRGV3 Gene

GeneLoc Exon Structure for
TRGV3
ECgene alternative splicing isoforms for
TRGV3

Expression for TRGV3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TRGV3 Gene

mRNA differential expression in normal tissues according to GTEx for TRGV3 Gene

This gene is overexpressed in Whole Blood (x11.5) and Spleen (x6.3).

NURSA nuclear receptor signaling pathways regulating expression of TRGV3 Gene:

TRGV3
genes like me logo Genes that share expression patterns with TRGV3: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRGV3 Gene

Orthologs for TRGV3 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TRGV3 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia -- 34
  • 53 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 43 (a)
ManyToMany
-- 34
  • 41 (a)
ManyToMany
-- 34
  • 40 (a)
ManyToMany
-- 34
  • 37 (a)
ManyToMany
-- 34
  • 35 (a)
ManyToMany
-- 34
  • 33 (a)
ManyToMany
-- 34
  • 32 (a)
ManyToMany
-- 34
  • 24 (a)
ManyToMany
Species where no ortholog for TRGV3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TRGV3 Gene

ENSEMBL:
Gene Tree for TRGV3 (if available)
TreeFam:
Gene Tree for TRGV3 (if available)

Paralogs for TRGV3 Gene

Paralogs for TRGV3 Gene

Pseudogenes.org Pseudogenes for TRGV3 Gene

genes like me logo Genes that share paralogs with TRGV3: view

Variants for TRGV3 Gene

Additional Variant Information for TRGV3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRGV3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRGV3 Gene

Disorders for TRGV3 Gene

Additional Disease Information for TRGV3

No disorders were found for TRGV3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TRGV3 Gene

Publications for TRGV3 Gene

  1. Variable region genes in the human T-cell rearranging gamma (TRG) locus: V-J junction and homology with the mouse genes. (PMID: 2969332) Huck S … Lefranc MP (The EMBO journal 1988) 2 3 58
  2. Diversity and rearrangement of the human T cell rearranging gamma genes: nine germ-line variable genes belonging to two subgroups. (PMID: 2938743) LeFranc MP … Rabbitts TH (Cell 1986) 2 3 58
  3. Human T-cell gamma genes contain N segments and have marked junctional variability. (PMID: 3453106) Quertermous T … Seidman JG (Nature 1986) 3 4 58
  4. Cloning and sequence analysis of complementary DNA encoding an aberrantly rearranged human T-cell gamma chain. (PMID: 3458221) Dialynas DP … Strominger JL (Proceedings of the National Academy of Sciences of the United States of America 1986) 3 4 58
  5. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier LW … Wilson RK (Nature 2003) 4 58

Products for TRGV3 Gene

Sources for TRGV3 Gene

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