Free for academic non-profit institutions. Other users need a Commercial license

Aliases for TRGV3 Gene

Aliases for TRGV3 Gene

  • T Cell Receptor Gamma Variable 3 2 3
  • T-Cell Receptor, Gamma, Variable Region V3 3
  • Variable Region V3 2
  • T-Cell Receptor 2
  • TCRGV3 3
  • Gamma 2
  • V1S3 3
  • TCRB 4

External Ids for TRGV3 Gene

Previous HGNC Symbols for TRGV3 Gene

  • TCRGV3

Previous GeneCards Identifiers for TRGV3 Gene

  • GC07U990107
  • GC07M038104
  • GC07M038138
  • GC07M038171
  • GC07M038364
  • GC07M038398
  • GC07M038283

Summaries for TRGV3 Gene

GeneCards Summary for TRGV3 Gene

TRGV3 (T Cell Receptor Gamma Variable 3) is a Protein Coding gene. GO annotations related to this gene include peptide antigen binding and MHC protein binding. An important paralog of this gene is TRGV5.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRGV3 Gene

Genomics for TRGV3 Gene

Genomic Location for TRGV3 Gene

Start:
38,358,512 bp from pter
End:
38,359,162 bp from pter
Size:
651 bases
Orientation:
Minus strand

Genomic View for TRGV3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TRGV3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRGV3 Gene

No data available for Regulatory Elements for TRGV3 Gene

Proteins for TRGV3 Gene

  • Protein details for TRGV3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P03979-TVC_HUMAN
    Recommended name:
    T-cell receptor gamma chain V region PT-gamma-1/2
    Protein Accession:
    P03979
    Secondary Accessions:

    Protein attributes for TRGV3 Gene

    Size:
    136 amino acids
    Molecular mass:
    15677 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • This is an aberrantly rearranged nucleotide sequence. Two bases are deleted at nucleotide position 357 in this clone. However, the protein sequence can be deduced from the mRNA sequence

neXtProt entry for TRGV3 Gene

Proteomics data for TRGV3 Gene at MOPED

Post-translational modifications for TRGV3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TRGV3 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRGV3 Gene

Domains for TRGV3 Gene

Gene Families for TRGV3 Gene

HGNC:
  • TRG :T cell receptors / TRG locus

Protein Domains for TRGV3 Gene

Suggested Antigen Peptide Sequences for TRGV3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRGV3: view

No data available for UniProtKB/Swiss-Prot for TRGV3 Gene

Function for TRGV3 Gene

Gene Ontology (GO) - Molecular Function for TRGV3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
GO:0042287 MHC protein binding NAS 3458221
GO:0042605 peptide antigen binding NAS 3458221
genes like me logo Genes that share ontologies with TRGV3: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TRGV3 Gene

Localization for TRGV3 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TRGV3 Gene COMPARTMENTS Subcellular localization image for TRGV3 gene
Compartment Confidence
plasma membrane 5
extracellular 3

Gene Ontology (GO) - Cellular Components for TRGV3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane NAS 3458221
genes like me logo Genes that share ontologies with TRGV3: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for TRGV3 Gene

Pathways for TRGV3 Gene

SuperPathways for TRGV3 Gene

No Data Available

Interacting Proteins for TRGV3 Gene

Gene Ontology (GO) - Biological Process for TRGV3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006955 immune response NAS 3458221
genes like me logo Genes that share ontologies with TRGV3: view

No data available for Pathways by source for TRGV3 Gene

Transcripts for TRGV3 Gene

mRNA/cDNA for TRGV3 Gene

(5) Selected AceView cDNA sequences:
(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TRGV3 Gene

No ASD Table

Relevant External Links for TRGV3 Gene

GeneLoc Exon Structure for
TRGV3
ECgene alternative splicing isoforms for
TRGV3

Expression for TRGV3 Gene

mRNA expression in normal human tissues for TRGV3 Gene

mRNA differential expression in normal tissues according to GTEx for TRGV3 Gene

This gene is overexpressed in Whole Blood (11.5) and Spleen (6.3).
genes like me logo Genes that share expressions with TRGV3: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for TRGV3 Gene

Orthologs for TRGV3 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TRGV3 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia -- 36
  • 53 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 37 (a)
ManyToMany
-- 36
  • 41 (a)
ManyToMany
-- 36
  • 24 (a)
ManyToMany
-- 36
  • 32 (a)
ManyToMany
-- 36
  • 35 (a)
ManyToMany
-- 36
  • 33 (a)
ManyToMany
-- 36
  • 40 (a)
ManyToMany
-- 36
  • 43 (a)
ManyToMany
Species with no ortholog for TRGV3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TRGV3 Gene

ENSEMBL:
Gene Tree for TRGV3 (if available)
TreeFam:
Gene Tree for TRGV3 (if available)

Paralogs for TRGV3 Gene

Paralogs for TRGV3 Gene

Pseudogenes.org Pseudogenes for TRGV3 Gene

genes like me logo Genes that share paralogs with TRGV3: view

Variants for TRGV3 Gene

Relevant External Links for TRGV3 Gene

HapMap Linkage Disequilibrium report
TRGV3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for TRGV3 Gene

Disorders for TRGV3 Gene

No disorders were found for TRGV3 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for TRGV3 Gene

Publications for TRGV3 Gene

  1. Diversity and rearrangement of the human T cell rearranging gamma genes: nine germ-line variable genes belonging to two subgroups. (PMID: 2938743) LeFranc M.P. … Rabbitts T.H. (Cell 1986) 2 3
  2. Variable region genes in the human T-cell rearranging gamma (TRG) locus: V-J junction and homology with the mouse genes. (PMID: 2969332) Huck S. … Lefranc M.P. (EMBO J. 1988) 2 3
  3. Human T-cell gamma genes contain N segments and have marked junctional variability. (PMID: 3453106) Quertermous T. … Seidman J.G. (Nature 1986) 3 4
  4. Cloning and sequence analysis of complementary DNA encoding an aberrantly rearranged human T-cell gamma chain. (PMID: 3458221) Dialynas D.P. … Strominger J.L. (Proc. Natl. Acad. Sci. U.S.A. 1986) 3 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for TRGV3 Gene

Sources for TRGV3 Gene

Back to Top

Content