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Aliases for TRGV3 Gene

Aliases for TRGV3 Gene

  • T Cell Receptor Gamma Variable 3 2 3 5
  • T-Cell Receptor, Gamma, Variable Region V3 3
  • Variable Region V3 2
  • T-Cell Receptor 2
  • TCRGV3 3
  • Gamma 2
  • TCRB 4
  • V1S3 3

External Ids for TRGV3 Gene

Previous HGNC Symbols for TRGV3 Gene

  • TCRGV3

Previous GeneCards Identifiers for TRGV3 Gene

  • GC07U990107
  • GC07M038104
  • GC07M038138
  • GC07M038171
  • GC07M038364
  • GC07M038398
  • GC07M038283
  • GC07M038441
  • GC07M038463

Summaries for TRGV3 Gene

GeneCards Summary for TRGV3 Gene

TRGV3 (T Cell Receptor Gamma Variable 3) is a Protein Coding gene. GO annotations related to this gene include peptide antigen binding and MHC protein binding. An important paralog of this gene is TRGV1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRGV3 Gene

Genomics for TRGV3 Gene

Regulatory Elements for TRGV3 Gene

Promoters for TRGV3 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around TRGV3 on UCSC Golden Path with GeneCards custom track

Genomic Location for TRGV3 Gene

Chromosome:
7
Start:
38,358,512 bp from pter
End:
38,359,162 bp from pter
Size:
651 bases
Orientation:
Minus strand

Genomic View for TRGV3 Gene

Genes around TRGV3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRGV3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRGV3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRGV3 Gene

Proteins for TRGV3 Gene

  • Protein details for TRGV3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P03979-TVC_HUMAN
    Recommended name:
    T-cell receptor gamma chain V region PT-gamma-1/2
    Protein Accession:
    P03979

    Protein attributes for TRGV3 Gene

    Size:
    136 amino acids
    Molecular mass:
    15677 Da
    Quaternary structure:
    No Data Available
    Miscellaneous:
    • This is an aberrantly rearranged nucleotide sequence. Two bases are deleted at nucleotide position 357 in this clone. However, the protein sequence can be deduced from the mRNA sequence.

neXtProt entry for TRGV3 Gene

Proteomics data for TRGV3 Gene at MOPED

Post-translational modifications for TRGV3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TRGV3 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRGV3 Gene

Domains & Families for TRGV3 Gene

Gene Families for TRGV3 Gene

Protein Domains for TRGV3 Gene

Suggested Antigen Peptide Sequences for TRGV3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRGV3: view

No data available for UniProtKB/Swiss-Prot for TRGV3 Gene

Function for TRGV3 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRGV3 Gene

Localization for TRGV3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TRGV3 Gene

Pathways & Interactions for TRGV3 Gene

SuperPathways for TRGV3 Gene

No Data Available

Interacting Proteins for TRGV3 Gene

Gene Ontology (GO) - Biological Process for TRGV3 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TRGV3 Gene

Drugs & Compounds for TRGV3 Gene

No Compound Related Data Available

Transcripts for TRGV3 Gene

mRNA/cDNA for TRGV3 Gene

(1) REFSEQ mRNAs :
(5) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TRGV3 Gene

No ASD Table

Relevant External Links for TRGV3 Gene

GeneLoc Exon Structure for
TRGV3
ECgene alternative splicing isoforms for
TRGV3

Expression for TRGV3 Gene

mRNA expression in normal human tissues for TRGV3 Gene

mRNA differential expression in normal tissues according to GTEx for TRGV3 Gene

This gene is overexpressed in Whole Blood (x11.5) and Spleen (x6.3).
genes like me logo Genes that share expression patterns with TRGV3: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for TRGV3 Gene

Orthologs for TRGV3 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TRGV3 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia -- 36
  • 53 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 37 (a)
ManyToMany
-- 36
  • 41 (a)
ManyToMany
-- 36
  • 24 (a)
ManyToMany
-- 36
  • 32 (a)
ManyToMany
-- 36
  • 35 (a)
ManyToMany
-- 36
  • 33 (a)
ManyToMany
-- 36
  • 40 (a)
ManyToMany
-- 36
  • 43 (a)
ManyToMany
Species with no ortholog for TRGV3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TRGV3 Gene

ENSEMBL:
Gene Tree for TRGV3 (if available)
TreeFam:
Gene Tree for TRGV3 (if available)

Paralogs for TRGV3 Gene

Paralogs for TRGV3 Gene

Pseudogenes.org Pseudogenes for TRGV3 Gene

genes like me logo Genes that share paralogs with TRGV3: view

Variants for TRGV3 Gene

Relevant External Links for TRGV3 Gene

HapMap Linkage Disequilibrium report
TRGV3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRGV3 Gene

Disorders for TRGV3 Gene

Relevant External Links for TRGV3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TRGV3

No disorders were found for TRGV3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TRGV3 Gene

Publications for TRGV3 Gene

  1. Variable region genes in the human T-cell rearranging gamma (TRG) locus: V-J junction and homology with the mouse genes. (PMID: 2969332) Huck S. … Lefranc M.P. (EMBO J. 1988) 2 3 67
  2. Diversity and rearrangement of the human T cell rearranging gamma genes: nine germ-line variable genes belonging to two subgroups. (PMID: 2938743) LeFranc M.P. … Rabbitts T.H. (Cell 1986) 2 3
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. The human T-cell receptor gamma (TRG) genes. (PMID: 2527426) Lefranc M.P. … Rabbitts T.H. (Trends Biochem. Sci. 1989) 3
  5. Human T-cell gamma genes contain N segments and have marked junctional variability. (PMID: 3453106) Quertermous T. … Seidman J.G. (Nature 1986) 3

Products for TRGV3 Gene

Sources for TRGV3 Gene

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