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Aliases for TRGV3 Gene

Aliases for TRGV3 Gene

  • T-Cell Receptor Gamma Variable 3 2 5
  • T-Cell Receptor, Gamma, Variable Region V3 2 3
  • T Cell Receptor Gamma Variable 3 2 3
  • TCRGV3 3 4
  • T-Cell Receptor Gamma V-Gamma-1.1 Region 4
  • TCRB 4
  • V1S3 3

External Ids for TRGV3 Gene

Previous HGNC Symbols for TRGV3 Gene

  • TCRGV3

Previous GeneCards Identifiers for TRGV3 Gene

  • GC07U990107
  • GC07M038104
  • GC07M038138
  • GC07M038171
  • GC07M038364
  • GC07M038398
  • GC07M038283
  • GC07M038441
  • GC07M038463
  • GC07M038477
  • GC07M038489
  • GC07M038502

Summaries for TRGV3 Gene

GeneCards Summary for TRGV3 Gene

TRGV3 (T-Cell Receptor Gamma Variable 3) is a Protein Coding gene. GO annotations related to this gene include peptide antigen binding and MHC protein binding. An important paralog of this gene is TRGV5.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRGV3 Gene

Genomics for TRGV3 Gene

Regulatory Elements for TRGV3 Gene

Enhancers for TRGV3 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07G038340 1.5 Ensembl ENCODE dbSUPER 10.3 +17.6 17592 3.3 HDGF PKNOX1 ATF1 CREB3L1 ARNT FOS KLF13 ZNF263 NCOA1 REST TRGV4 TRGV3 TRGV5P TRG-AS1 TRGV6
GH07G038362 1.2 Ensembl ENCODE dbSUPER 10.1 -4.0 -4034 2.0 ZNF263 CTCF ZNF146 RB1 MTA2 TRIM22 GATAD2B NFXL1 EBF1 RAD21 TRGV4 TRGV5P TRGV3 GC07P038360 TRGV2
GH07G038357 1.2 Ensembl ENCODE dbSUPER 9.8 -0.5 -539 3.8 CTCF ATF1 RB1 BACH1 NFXL1 RAD21 ZBTB48 EGR1 ZNF143 SMC3 TRGV4 TRGV5P TRGV5 TRGV3 AMPH TRGV7 GC07P038360
GH07G038344 1.3 Ensembl ENCODE dbSUPER 8.4 +13.7 13652 3.0 HDGF CTCF NFXL1 RAD21 TCF12 GATA2 EGR1 ZNF366 ZBTB48 EED TRGV4 TRGV5P TRGV3 AMPH TRGV6 TRGV5
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TRGV3 on UCSC Golden Path with GeneCards custom track

Genomic Location for TRGV3 Gene

38,358,512 bp from pter
38,359,162 bp from pter
651 bases
Minus strand

Genomic View for TRGV3 Gene

Genes around TRGV3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRGV3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRGV3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRGV3 Gene

Proteins for TRGV3 Gene

  • Protein details for TRGV3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    T cell receptor gamma variable 3
    Protein Accession:
    Secondary Accessions:
    • A0A075B6L3

    Protein attributes for TRGV3 Gene

    118 amino acids
    Molecular mass:
    13664 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRGV3 Gene

Post-translational modifications for TRGV3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TRGV3 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRGV3 Gene

Domains & Families for TRGV3 Gene

Gene Families for TRGV3 Gene

Protein Domains for TRGV3 Gene

Suggested Antigen Peptide Sequences for TRGV3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRGV3: view

No data available for UniProtKB/Swiss-Prot for TRGV3 Gene

Function for TRGV3 Gene

Gene Ontology (GO) - Molecular Function for TRGV3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0042287 MHC protein binding NAS 3458221
GO:0042605 peptide antigen binding NAS 3458221
genes like me logo Genes that share ontologies with TRGV3: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRGV3 Gene

Localization for TRGV3 Gene

Gene Ontology (GO) - Cellular Components for TRGV3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane NAS 3458221
genes like me logo Genes that share ontologies with TRGV3: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for TRGV3 Gene

Pathways & Interactions for TRGV3 Gene

SuperPathways for TRGV3 Gene

No Data Available

Interacting Proteins for TRGV3 Gene

Gene Ontology (GO) - Biological Process for TRGV3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006955 immune response NAS 3458221
genes like me logo Genes that share ontologies with TRGV3: view

No data available for Pathways by source and SIGNOR curated interactions for TRGV3 Gene

Transcripts for TRGV3 Gene

mRNA/cDNA for TRGV3 Gene

(1) REFSEQ mRNAs :
(5) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TRGV3 Gene

No ASD Table

Relevant External Links for TRGV3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TRGV3 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TRGV3 Gene

mRNA differential expression in normal tissues according to GTEx for TRGV3 Gene

This gene is overexpressed in Whole Blood (x11.5) and Spleen (x6.3).

NURSA nuclear receptor signaling pathways regulating expression of TRGV3 Gene:

genes like me logo Genes that share expression patterns with TRGV3: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRGV3 Gene

Orthologs for TRGV3 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TRGV3 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia -- 35
  • 53 (a)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 43 (a)
-- 35
  • 41 (a)
-- 35
  • 40 (a)
-- 35
  • 37 (a)
-- 35
  • 35 (a)
-- 35
  • 33 (a)
-- 35
  • 32 (a)
-- 35
  • 24 (a)
Species where no ortholog for TRGV3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TRGV3 Gene

Gene Tree for TRGV3 (if available)
Gene Tree for TRGV3 (if available)

Paralogs for TRGV3 Gene

Paralogs for TRGV3 Gene Pseudogenes for TRGV3 Gene

genes like me logo Genes that share paralogs with TRGV3: view

Variants for TRGV3 Gene

Relevant External Links for TRGV3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRGV3 Gene

Disorders for TRGV3 Gene

Relevant External Links for TRGV3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for TRGV3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TRGV3 Gene

Publications for TRGV3 Gene

  1. Variable region genes in the human T-cell rearranging gamma (TRG) locus: V-J junction and homology with the mouse genes. (PMID: 2969332) Huck S. … Lefranc M.P. (EMBO J. 1988) 2 3 64
  2. Diversity and rearrangement of the human T cell rearranging gamma genes: nine germ-line variable genes belonging to two subgroups. (PMID: 2938743) LeFranc M.P. … Rabbitts T.H. (Cell 1986) 2 3 64
  3. Human T-cell gamma genes contain N segments and have marked junctional variability. (PMID: 3453106) Quertermous T. … Seidman J.G. (Nature 1986) 3 4 64
  4. Cloning and sequence analysis of complementary DNA encoding an aberrantly rearranged human T-cell gamma chain. (PMID: 3458221) Dialynas D.P. … Strominger J.L. (Proc. Natl. Acad. Sci. U.S.A. 1986) 3 4 64
  5. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 4 64

Products for TRGV3 Gene

Sources for TRGV3 Gene

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