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Aliases for TRGV3 Gene

Aliases for TRGV3 Gene

  • T Cell Receptor Gamma Variable 3 2 3 5
  • T-Cell Receptor, Gamma, Variable Region V3 2 3
  • TCRGV3 3 4
  • T-Cell Receptor Gamma V-Gamma-1.1 Region 4
  • TCRB 4
  • V1S3 3

External Ids for TRGV3 Gene

Previous HGNC Symbols for TRGV3 Gene

  • TCRGV3

Previous GeneCards Identifiers for TRGV3 Gene

  • GC07U990107
  • GC07M038104
  • GC07M038138
  • GC07M038171
  • GC07M038364
  • GC07M038398
  • GC07M038283
  • GC07M038441
  • GC07M038463
  • GC07M038477
  • GC07M038489

Summaries for TRGV3 Gene

GeneCards Summary for TRGV3 Gene

TRGV3 (T Cell Receptor Gamma Variable 3) is a Protein Coding gene. GO annotations related to this gene include peptide antigen binding and MHC protein binding. An important paralog of this gene is TRGV5.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRGV3 Gene

Genomics for TRGV3 Gene

Regulatory Elements for TRGV3 Gene

Enhancers for TRGV3 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07F038357 0.2 Ensembl 10.4 +2.0 1962 0.4 POLR2A TRGV3 GC07M038508 GC07P038357
GH07F038353 0.8 Ensembl ENCODE 10.1 +4.6 4562 3.2 ZNF263 CTCF ZNF146 IKZF1 NFXL1 RAD21 TRGV4 TRGV5P TRGV3 ENSG00000272908 GC07M038509
GH07F038362 0.5 ENCODE 10.1 -4.0 -4037 2.0 ZNF263 CTCF ZNF146 MTA2 TRIM22 NFXL1 EBF1 RAD21 ZNF366 IKZF1 TRGV4 TRGV5P TRGV3 GC07P038360 TRGV2
GH07F038358 0.4 ENCODE 9.8 0.0 -39 2.2 ZNF263 CTCF ATF1 ZNF654 TRIM22 NFXL1 REST RAD21 IKZF1 ZNF143 TRGV4 TRGV5P TRGV5 TRGV3 AMPH GC07P038360
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around TRGV3 on UCSC Golden Path with GeneCards custom track

Promoters for TRGV3 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00001891060 262 201 ZNF263 ATF1 IKZF1
ENSR00001891061 -638 401 ZNF263 CTCF ATF1
ENSR00001891059 662 201 IKZF1

Genomic Location for TRGV3 Gene

38,358,512 bp from pter
38,359,162 bp from pter
651 bases
Minus strand

Genomic View for TRGV3 Gene

Genes around TRGV3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRGV3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRGV3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRGV3 Gene

Proteins for TRGV3 Gene

  • Protein details for TRGV3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    T cell receptor gamma variable 3
    Protein Accession:
    Secondary Accessions:
    • A0A075B6L3

    Protein attributes for TRGV3 Gene

    118 amino acids
    Molecular mass:
    13664 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRGV3 Gene

Post-translational modifications for TRGV3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TRGV3 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRGV3 Gene

Domains & Families for TRGV3 Gene

Gene Families for TRGV3 Gene

Protein Domains for TRGV3 Gene

Suggested Antigen Peptide Sequences for TRGV3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 Ig-like (immunoglobulin-like) domain.
  • Contains 1 Ig-like (immunoglobulin-like) domain.
genes like me logo Genes that share domains with TRGV3: view

Function for TRGV3 Gene

Gene Ontology (GO) - Molecular Function for TRGV3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0042287 MHC protein binding NAS 3458221
GO:0042605 peptide antigen binding NAS 3458221
genes like me logo Genes that share ontologies with TRGV3: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRGV3 Gene

Localization for TRGV3 Gene

Gene Ontology (GO) - Cellular Components for TRGV3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane NAS 3458221
genes like me logo Genes that share ontologies with TRGV3: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for TRGV3 Gene

Pathways & Interactions for TRGV3 Gene

SuperPathways for TRGV3 Gene

No Data Available

Interacting Proteins for TRGV3 Gene

Gene Ontology (GO) - Biological Process for TRGV3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006955 immune response NAS 3458221
genes like me logo Genes that share ontologies with TRGV3: view

No data available for Pathways by source and SIGNOR curated interactions for TRGV3 Gene

Transcripts for TRGV3 Gene

mRNA/cDNA for TRGV3 Gene

(1) REFSEQ mRNAs :
(5) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TRGV3 Gene

No ASD Table

Relevant External Links for TRGV3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TRGV3 Gene

mRNA expression in normal human tissues for TRGV3 Gene

mRNA differential expression in normal tissues according to GTEx for TRGV3 Gene

This gene is overexpressed in Whole Blood (x11.5) and Spleen (x6.3).

NURSA nuclear receptor signaling pathways regulating expression of TRGV3 Gene:

genes like me logo Genes that share expression patterns with TRGV3: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for TRGV3 Gene

Orthologs for TRGV3 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TRGV3 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia -- 35
  • 53 (a)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 43 (a)
-- 35
  • 41 (a)
-- 35
  • 40 (a)
-- 35
  • 37 (a)
-- 35
  • 35 (a)
-- 35
  • 33 (a)
-- 35
  • 32 (a)
-- 35
  • 24 (a)
Species where no ortholog for TRGV3 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TRGV3 Gene

Gene Tree for TRGV3 (if available)
Gene Tree for TRGV3 (if available)

Paralogs for TRGV3 Gene

Paralogs for TRGV3 Gene Pseudogenes for TRGV3 Gene

genes like me logo Genes that share paralogs with TRGV3: view

Variants for TRGV3 Gene

Relevant External Links for TRGV3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRGV3 Gene

Disorders for TRGV3 Gene

Relevant External Links for TRGV3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for TRGV3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TRGV3 Gene

Publications for TRGV3 Gene

  1. Variable region genes in the human T-cell rearranging gamma (TRG) locus: V-J junction and homology with the mouse genes. (PMID: 2969332) Huck S. … Lefranc M.P. (EMBO J. 1988) 2 3 64
  2. Diversity and rearrangement of the human T cell rearranging gamma genes: nine germ-line variable genes belonging to two subgroups. (PMID: 2938743) LeFranc M.P. … Rabbitts T.H. (Cell 1986) 2 3 64
  3. Cloning and sequence analysis of complementary DNA encoding an aberrantly rearranged human T-cell gamma chain. (PMID: 3458221) Dialynas D.P. … Strominger J.L. (Proc. Natl. Acad. Sci. U.S.A. 1986) 3 4 64
  4. Human T-cell gamma genes contain N segments and have marked junctional variability. (PMID: 3453106) Quertermous T. … Seidman J.G. (Nature 1986) 3 4 64
  5. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 4 64

Products for TRGV3 Gene

Sources for TRGV3 Gene

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