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Aliases for TRGC1 Gene

Aliases for TRGC1 Gene

  • T Cell Receptor Gamma Constant 1 2 3
  • T-Cell Receptor, Gamma, Constant Region C1 2 3
  • TCRGC1 2 3
  • T-Cell Receptor Gamma Constant 1 5
  • TCRG 3
  • C1 3

External Ids for TRGC1 Gene

Previous HGNC Symbols for TRGC1 Gene

  • TCRGC1

Previous GeneCards Identifiers for TRGC1 Gene

  • GC07U990098
  • GC07M038007
  • GC07M038040
  • GC07M038072
  • GC07M038266
  • GC07M038300
  • GC07M038338
  • GC07M038327
  • GC07M038401
  • GC07M038416
  • GC07M038436
  • GC07M038714
  • GC07M038944
  • GC07M039178

Summaries for TRGC1 Gene

GeneCards Summary for TRGC1 Gene

TRGC1 (T Cell Receptor Gamma Constant 1) is a Protein Coding gene. An important paralog of this gene is TRGC2.

Additional gene information for TRGC1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRGC1 Gene

Genomics for TRGC1 Gene

GeneHancer (GH) Regulatory Elements for TRGC1 Gene

Promoters and enhancers for TRGC1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH07I038264 Enhancer 0.6 ENCODE dbSUPER 550.8 +0.5 540 1.3 GATA3 FOXA1 GC07P038264 TRGC1 TRGC2 TARP TRG
GH07I038242 Enhancer 1.2 FANTOM5 Ensembl ENCODE dbSUPER 6.5 +22.5 22528 1.7 IRF9 ZNF316 MAFG CEBPB CEBPG EMSY TRGC2 STARD3NL TRGC1 TRG
GH07I037941 Enhancer 1.2 Ensembl ENCODE 5.2 +322.0 322036 4.3 HDGF PKNOX1 FOXA2 SMAD1 MLX ARID4B SIN3A DMAP1 ZNF48 ETS1 SFRP4 EPDR1 TRGC1 LOC105375236 NME8
GH07I038255 Enhancer 1 Ensembl ENCODE dbSUPER 6 +8.7 8723 2 NR4A1 CEBPB CEBPG ZBTB40 POLR2A IKZF1 ATF7 ZNF24 NFE2 TRGJP2 TRGC2 TRGC1 GC07P038264 TARP TRG
GH07I038238 Enhancer 0.5 dbSUPER 7.3 +25.9 25868 2.2 ATF1 L3MBTL2 MGA SP7 STARD3NL TRGC2 TRGC1 TRG
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around TRGC1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for TRGC1 Gene

Genomic Locations for TRGC1 Gene
chr7:38,257,879-38,265,678
(GRCh38/hg38)
Size:
7,800 bases
Orientation:
Minus strand
chr7:38,297,480-38,305,279
(GRCh37/hg19)

Genomic View for TRGC1 Gene

Genes around TRGC1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRGC1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRGC1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRGC1 Gene

Proteins for TRGC1 Gene

  • Protein details for TRGC1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P0CF51-TRGC1_HUMAN
    Recommended name:
    T-cell receptor gamma chain C region 1
    Protein Accession:
    P0CF51

    Protein attributes for TRGC1 Gene

    Size:
    173 amino acids
    Molecular mass:
    19804 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for TRGC1 Gene

neXtProt entry for TRGC1 Gene

Post-translational modifications for TRGC1 Gene

No Post-translational modifications

Other Protein References for TRGC1 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRGC1 Gene

Domains & Families for TRGC1 Gene

Gene Families for TRGC1 Gene

Protein Domains for TRGC1 Gene

Suggested Antigen Peptide Sequences for TRGC1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRGC1: view

No data available for UniProtKB/Swiss-Prot for TRGC1 Gene

Function for TRGC1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRGC1 Gene

Localization for TRGC1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TRGC1 Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TRGC1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TRGC1: view

No data available for Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for TRGC1 Gene

Pathways & Interactions for TRGC1 Gene

SuperPathways for TRGC1 Gene

No Data Available

Interacting Proteins for TRGC1 Gene

Selected Interacting proteins: P0CF51-TRGC1_HUMAN for TRGC1 Gene via IID

Symbol External ID(s) Details
CD1D
TRDC

Gene Ontology (GO) - Biological Process for TRGC1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TRGC1 Gene

Drugs & Compounds for TRGC1 Gene

No Compound Related Data Available

Transcripts for TRGC1 Gene

mRNA/cDNA for TRGC1 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for TRGC1 Gene

No ASD Table

Relevant External Links for TRGC1 Gene

GeneLoc Exon Structure for
TRGC1
ECgene alternative splicing isoforms for
TRGC1

Expression for TRGC1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TRGC1 Gene

mRNA differential expression in normal tissues according to GTEx for TRGC1 Gene

This gene is overexpressed in Prostate (x26.6) and Whole Blood (x11.1).

NURSA nuclear receptor signaling pathways regulating expression of TRGC1 Gene:

TRGC1
genes like me logo Genes that share expression patterns with TRGC1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRGC1 Gene

Orthologs for TRGC1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TRGC1 Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia Tcrg-C1 34
  • 69 (a)
ManyToMany
Tcrg-C3 34
  • 69 (a)
ManyToMany
Tcrg-C2 34
  • 68 (a)
ManyToMany
Tcrg-C4 34
  • 49 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia -- 34
  • 54 (a)
ManyToMany
-- 34
  • 31 (a)
ManyToMany
-- 34
  • 30 (a)
ManyToMany
-- 34
  • 30 (a)
ManyToMany
-- 34
  • 29 (a)
ManyToMany
dog
(Canis familiaris)
Mammalia -- 34
  • 52 (a)
ManyToMany
-- 34
  • 49 (a)
ManyToMany
-- 34
  • 43 (a)
ManyToMany
-- 34
  • 39 (a)
ManyToMany
-- 34
  • 36 (a)
ManyToMany
-- 34
  • 29 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 31 (a)
ManyToMany
-- 34
  • 30 (a)
ManyToMany
-- 34
  • 26 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 30 (a)
OneToMany
chicken
(Gallus gallus)
Aves -- 34
  • 13 (a)
OneToMany
Species where no ortholog for TRGC1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TRGC1 Gene

ENSEMBL:
Gene Tree for TRGC1 (if available)
TreeFam:
Gene Tree for TRGC1 (if available)

Paralogs for TRGC1 Gene

Paralogs for TRGC1 Gene

(3) SIMAP similar genes for TRGC1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with TRGC1: view

Variants for TRGC1 Gene

Additional Variant Information for TRGC1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRGC1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRGC1 Gene

Disorders for TRGC1 Gene

No disorders were found for TRGC1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for TRGC1 Gene

Publications for TRGC1 Gene

  1. Genetic polymorphism and exon changes of the constant regions of the human T-cell rearranging gene gamma. (PMID: 2879283) Lefranc MP … Rabbitts TH (Proceedings of the National Academy of Sciences of the United States of America 1986) 2 3 4 58
  2. T cell receptor gamma cDNA in human fetal liver and thymus: variable regions of gamma chains are restricted to V gamma I or V9, due to the absence of splicing of the V10 and V11 leader intron. (PMID: 8125127) Zhang XM … Huck S (European journal of immunology 1994) 22 58
  3. The human T-cell receptor gamma (TRG) genes. (PMID: 2527426) Lefranc MP … Rabbitts TH (Trends in biochemical sciences 1989) 3 58

Products for TRGC1 Gene

Sources for TRGC1 Gene

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