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Aliases for TRGC1 Gene

Aliases for TRGC1 Gene

  • T Cell Receptor Gamma Constant 1 2 3 5
  • T-Cell Receptor, Gamma, Constant Region C1 3
  • Constant Region C1 2
  • T-Cell Receptor 2
  • TCRGC1 3
  • Gamma 2
  • TCRG 3
  • C1 3

External Ids for TRGC1 Gene

Previous HGNC Symbols for TRGC1 Gene

  • TCRGC1

Previous GeneCards Identifiers for TRGC1 Gene

  • GC07U990098
  • GC07M038007
  • GC07M038040
  • GC07M038072
  • GC07M038266
  • GC07M038300
  • GC07M038338
  • GC07M038327
  • GC07M038401
  • GC07M038416
  • GC07M038436
  • GC07M038714
  • GC07M038944
  • GC07M039178

Summaries for TRGC1 Gene

GeneCards Summary for TRGC1 Gene

TRGC1 (T Cell Receptor Gamma Constant 1) is a Protein Coding gene. An important paralog of this gene is TRGC2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRGC1 Gene

Genomics for TRGC1 Gene

Regulatory Elements for TRGC1 Gene

Enhancers for TRGC1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around TRGC1 on UCSC Golden Path with GeneCards custom track

Promoters for TRGC1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around TRGC1 on UCSC Golden Path with GeneCards custom track

Genomic Location for TRGC1 Gene

38,257,879 bp from pter
38,265,678 bp from pter
7,800 bases
Minus strand

Genomic View for TRGC1 Gene

Genes around TRGC1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRGC1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRGC1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRGC1 Gene

Proteins for TRGC1 Gene

  • Protein details for TRGC1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    T-cell receptor gamma chain C region 1
    Protein Accession:

    Protein attributes for TRGC1 Gene

    173 amino acids
    Molecular mass:
    19804 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for TRGC1 Gene

neXtProt entry for TRGC1 Gene

Proteomics data for TRGC1 Gene at MOPED

Post-translational modifications for TRGC1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TRGC1 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRGC1 Gene

Domains & Families for TRGC1 Gene

Gene Families for TRGC1 Gene

Protein Domains for TRGC1 Gene

Suggested Antigen Peptide Sequences for TRGC1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 Ig-like (immunoglobulin-like) domain.
  • Contains 1 Ig-like (immunoglobulin-like) domain.
genes like me logo Genes that share domains with TRGC1: view

Function for TRGC1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRGC1 Gene

Localization for TRGC1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TRGC1 Gene

Membrane; Single-pass membrane protein.

No data available for Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TRGC1 Gene

Pathways & Interactions for TRGC1 Gene

SuperPathways for TRGC1 Gene

No Data Available

Interacting Proteins for TRGC1 Gene

Gene Ontology (GO) - Biological Process for TRGC1 Gene


No data available for Pathways by source and SIGNOR curated interactions for TRGC1 Gene

Drugs & Compounds for TRGC1 Gene

No Compound Related Data Available

Expression for TRGC1 Gene

mRNA expression in normal human tissues for TRGC1 Gene

mRNA differential expression in normal tissues according to GTEx for TRGC1 Gene

This gene is overexpressed in Prostate (x26.6) and Whole Blood (x11.1).
genes like me logo Genes that share expression patterns with TRGC1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for TRGC1 Gene

Orthologs for TRGC1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TRGC1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia -- 36
  • 54 (a)
-- 36
  • 30 (a)
-- 36
  • 29 (a)
-- 36
  • 30 (a)
-- 36
  • 31 (a)
(Canis familiaris)
Mammalia -- 36
  • 49 (a)
-- 36
  • 39 (a)
-- 36
  • 43 (a)
-- 36
  • 36 (a)
-- 36
  • 29 (a)
-- 36
  • 52 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 30 (a)
(Mus musculus)
Mammalia Tcrg-C1 36
  • 69 (a)
Tcrg-C2 36
  • 68 (a)
Tcrg-C3 36
  • 69 (a)
Tcrg-C4 36
  • 49 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 30 (a)
-- 36
  • 31 (a)
-- 36
  • 26 (a)
(Gallus gallus)
Aves -- 36
  • 13 (a)
Species with no ortholog for TRGC1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TRGC1 Gene

Gene Tree for TRGC1 (if available)
Gene Tree for TRGC1 (if available)

Paralogs for TRGC1 Gene

Paralogs for TRGC1 Gene

(3) SIMAP similar genes for TRGC1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with TRGC1: view

Variants for TRGC1 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Relevant External Links for TRGC1 Gene

Disorders for TRGC1 Gene

No disorders were found for TRGC1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for TRGC1 Gene

Publications for TRGC1 Gene

  1. Genetic polymorphism and exon changes of the constant regions of the human T-cell rearranging gene gamma. (PMID: 2879283) Lefranc M.P. … Rabbitts T.H. (Proc. Natl. Acad. Sci. U.S.A. 1986) 2 3 4 67
  2. T cell receptor gamma cDNA in human fetal liver and thymus: variable regions of gamma chains are restricted to V gamma I or V9, due to the absence of splicing of the V10 and V11 leader intron. (PMID: 8125127) Zhang X.M. … Huck S. (Eur. J. Immunol. 1994) 23
  3. The human T-cell receptor gamma (TRG) genes. (PMID: 2527426) Lefranc M.P. … Rabbitts T.H. (Trends Biochem. Sci. 1989) 3

Products for TRGC1 Gene

Sources for TRGC1 Gene