TRGC1 Gene
protein-coding GIFtS : 22 GCID: GC07 M038714
T cell receptor gamma constant 1 TCRGC1 )
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Aliasesfor TRGC1 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases T Cell Receptor Gamma Constant 1 1 2 C11 2 TCRGC11 2
Export aliases for TRGC1 gene to outside databases Previous GC identifers: GC07U990098 GC07M038007 GC07M038040 GC07M038072 GC07M038266 GC07M038300 GC07M038338 GC07M038327 GC07M038401 GC07M038416 GC07M038436
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Summariesfor TRGC1 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section
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Genomic Viewsfor TRGC1 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,miRBase ,UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section Regulatory elements: Search SABiosciences Regulatory transcription factor binding sites for TRGC1 Other transcription factors Search SABiosciences Chromatin IP Primers for TRGC1 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRGC1
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 7p14 Ensembl cytogenetic band: 7p14.1 HGNC cytogenetic band: 7p14 TRGC1 Gene in genomic location: bands according to Ensembl, locations according to
Entrez Gene Ensembl GeneLoc information about chromosome 7 GeneLoc Exon Structure
GeneLoc location for GC07M038714: view genomic region
(about GC identifiers )
Start: 38,297,480 bp from pter End:
38,305,279 bp from pter
Size: 7,800 bases Orientation:
minus strand
1 alternative location : Chr 7-,CRA_TCAG 38,337,370-38,342,961
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Proteinsfor TRGC1 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: TRGC1_HUMAN, P0CF51 See
protein sequence )Recommended Name: Size : 173 amino acids; 19804 DaSubcellular location : Membrane; Single-pass membrane protein (Potential)Explore the universe of human proteins at neXtProt for TRGC1: NX_P0CF51 TRGC1 Protein expression data from MOPED and PaxDb : About this image
ENSEMBL proteins: ENSP00000404817 Human Recombinant Protein Products: Gene Ontology (GO): 1 cellular component term (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0016021 integral to membrane
IEA --
About GeneDecksing TRGC1 Antibody Products: Assay Products for TRGC1:
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Protein
Domains /for TRGC1 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section About GeneDecksing 3 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry P0CF51 ProtoNet protein and cluster: P0CF51
UniProtKB/Swiss-Prot: TRGC1_HUMAN, P0CF51 Similarity : Contains 1 Ig-like (immunoglobulin-like) domain
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Functionfor TRGC1 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section
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Pathways & Interactionsfor TRGC1 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TRGC1 STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)1 Interacting protein for TRGC1 (ENSP00000404817 4 via UniProtKB, MINT, STRING , and/or I2D About this table
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Drugs & Compoundsfor TRGC1 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for TRGC1 TRGC1
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Transcriptsfor TRGC1 gene (Secondary structures according to
fRNAdb ,Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC , GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,EMD Millipore ,
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section 1 Ensembl transcript including schematic representation, and UCSC links where relevant : ENST00000443402 (uc003tgb.2 uc003tgc.1 uc003tgd.1 uc003tge.1 )24/359 AceView cDNA sequences (see all 359 ):
NM_001003806 BM478583 AW575113 CR605178 BX281781 BQ002856 NM_001003799 R33649 AV716204 AI668836 BX504327 AV715641 BF679123 CA449324 BC072387 BV205012 BE326754 BM922364 BC039725 BF679325 BV205029 BF674593 BC062761 AI972955 GeneLoc Exon Structure
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Expression for TRGC1 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section TRGC1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: --
About this image See TRGC1 Protein Expression from SPIRE MOPED and PaxDB SABiosciences Custom PCR Arrays for TRGC1 Primer Browse OriGene genome-wide validated SYBR primer pairs Browse OriGene validated miRNA SYBR primer pairs Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat TRGC1 Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRGC1 Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRGC1
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Orthologsfor TRGC1 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section Orthologs for TRGC1 gene from 1/4 species (see all 4 ) About this table
Organism
Taxonomic
Gene
Description
Human
Orthology
Details
chicken Aves --
Uncharacterized protein
14(a)
1 → many
2(49156863-49237340)
Species with no ortholog for TRGC1 ENSEMBL Gene Tree for TRGC1 (if available)TreeFam Gene Tree for TRGC1 (if available)
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Paralogsfor TRGC1 gene (Paralogs according to
1 HomoloGene ,2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for TRGC1 gene TRGC2 2 6 SIMAP similar genes for TRGC1 using alignment to 1 protein entry: TRGC1_HUMAN :TARP TRGC2 DKFZp667J0810 IGLC2 IGLC6 IGLC7 About GeneDecksing
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Genomic Variantsfor TRGC1 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section SABiosciences Cancer Mutation PCR Assays
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Disorders
/ Diseasesfor TRGC1 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
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Publicationsfor TRGC1 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for TRGC1 gene integrated from 9 sources :(articles sorted by number of sources associating them with TRGC1) Utopia : connect your pdf to the dynamic
Genetic polymorphism and exon changes of the constant regions of the human T-cell rearranging gene gamma. (PubMed id 2879283) 1 , 2 , 3(1986) The human T-cell receptor gamma (TRG) genes. (PubMed id 2527426) 1 (1989) T cell receptor gamma cDNA in human fetal liver and t hymus: variable regions of gamma chains are restricted to V gamma I or V9, due to the absence of splicing of the V10 and V11 leader intron. (PubMed id 8125127) 9 Zhang X.M....Huck S. (1994)
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External Searches for TRGC1 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing TRGC1 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing TRGC1 gene
(According to HUGE )
About This Section --
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Specialized Databases showing TRGC1 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description PharmGKB entry for TRGC1 Pharmacogenomics, SNPs, Pathways IMGT entry for TRGC1The international I mM unoG eneT ics information system® specializing in Immunoglobulins (IG), T cell receptors (TR), Major Histocompatibility Complex (MHC) and related proteins of the immune system (RPI) of human and other vertebrate species. IMGT/GENE-DB http://www.imgt.org/IMGT_GENE-DB/GENElect?query=2+TRGC1&species=Homo+sapiens
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About This Section Patent Information for TRGC1 gene: TRGC1 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor TRGC1 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TRGC1 Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TRGC1 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRGC1 Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TRGC1 Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRGC1 Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRGC1
Search Tocris compounds for TRGC1
Search ThermoFisher Antibodies for TRGC1
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TRGC1
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