Aliases for TRERF1 Gene
External Ids for TRERF1 Gene
Previous Symbols for TRERF1 Gene
This gene encodes a zinc-finger transcriptional regulating protein which interacts with CBP/p300 to regulate the human gene CYP11A1. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
GeneCards Summary for TRERF1 Gene
TRERF1 (Transcriptional Regulating Factor 1) is a Protein Coding gene. Diseases associated with TRERF1 include estrogen resistance and breast cancer. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity and transcription factor binding. An important paralog of this gene is ZNF541.
UniProtKB/Swiss-Prot for TRERF1 Gene
Binds DNA and activates transcription of CYP11A1. Interaction with CREBBP and EP300 results in a synergistic transcriptional activation of CYP11A1.