Aliases for TRERF1 Gene
External Ids for TRERF1 Gene
Previous HGNC Symbols for TRERF1 Gene
Previous GeneCards Identifiers for TRERF1 Gene
This gene encodes a zinc-finger transcriptional regulating protein which interacts with CBP/p300 to regulate the human gene CYP11A1. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014]
GeneCards Summary for TRERF1 Gene
TRERF1 (Transcriptional Regulating Factor 1) is a Protein Coding gene. Diseases associated with TRERF1 include Swayback and Estrogen Resistance. Among its related pathways are Mesodermal Commitment Pathway. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and transcription factor binding. An important paralog of this gene is ELMSAN1.
UniProtKB/Swiss-Prot for TRERF1 Gene
Binds DNA and activates transcription of CYP11A1. Interaction with CREBBP and EP300 results in a synergistic transcriptional activation of CYP11A1.