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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

TREML1 Gene

protein-coding GIFtS: 48
GCID: GC06M041120

triggering receptor expressed on myeloid cells-like 1

Explore 4 diseases affiliated with
TREML1 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Triggering Receptor Expressed On Myeloid Cells-Like 1¹ ²		TLT-1² ³
TLT1¹ ² ³ ⁵		GLTL1825²
DJ238O23.3¹		PRO3438²
Triggering Receptor Expressed On Myeloid Cells-Like Protein 1² ³		Trem-Like Transcript 1 Protein²

External Ids:	HGNC: 20434¹	Entrez Gene: 340205²	Ensembl: ENSG00000161911⁷	OMIM: 609714⁵	UniProtKB: Q86YW5³

Export aliases for TREML1 gene to outside databases

Previous GC identifers: GC06M041118 GC06M041164 GC06M041225 GC06M040835

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for TREML1:

This gene encodes a member of the triggering receptor expressed on myeloid cells-like (TREM) family. The encoded

protein is a type 1 single Ig domain orphan receptor localized to the alpha-granule membranes of platelets. The

encoded protein is involved in platelet aggregation, inflammation, and cellular activation and has been linked to Gray

platelet syndrome. Alternative splicing results in multiple transcript variants (provided by RefSeq, Nov 2012)

UniProtKB/Swiss-Prot: TRML1_HUMAN, Q86YW5

Function: Cell surface receptor that may play a role in the innate and adaptive immune response

Gene Wiki entry for TREML1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000006.11 NC_018917.1 NT_007592.15

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the TREML1 gene promoter:
AML1a p53 Bach2 NRSF form 1 NRSF form 2 CREB FOXJ2 (long isoform) HOXA5 FOXJ2 ATF
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: TREML1 promoter sequence

Search SABiosciences Chromatin IP Primers for TREML1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TREML1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.1 Ensembl cytogenetic band: 6p21.1 HGNC cytogenetic band: 6p21.1

TREML1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
TREML1 gene location

GeneLoc information about chromosome 6 GeneLoc Exon Structure

GeneLoc location for GC06M041120: view genomic region (about GC identifiers)

Start:	41,117,080 bp from pter	End:	41,122,075 bp from pter
Size:	4,996 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: TRML1_HUMAN, Q86YW5 (See protein sequence)

Recommended Name: Trem-like transcript 1 protein precursor

Size: 311 amino acids; 32679 Da

Subunit: When phosphorylated, interacts with PTPN6 (By similarity). When phosphorylated, interacts with PTPN11

Subcellular location: Cell membrane; Single-pass type I membrane protein. Cytoplasm. Note=Sequestered in cytoplasmic

vesicles in resting platelets. Transported to the cell surface after stimulation by thrombin. Soluble fragments can be

released into the serum by proteolysis

1 PDB 3D structure from and Proteopedia for TREML1:

2FRG (3D)

Secondary accessions: Q496B3 Q8IWY1 Q8IWY2

Alternative splicing: 3 isoforms: Q86YW5-1 Q86YW5-2 Q86YW5-3

Explore the universe of human proteins at neXtProt for TREML1: NX_Q86YW5

Post-translational modifications:

Phosphorylated on tyrosine residues¹

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q86YW5

TREML1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (3 alternative transcripts):

NP_001258736.1 NP_001258737.1 NP_835468.1

ENSEMBL proteins:

ENSP00000362219 ENSP00000402855 ENSP00000400405

Human Recombinant Protein Products:

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	Browse ProSpec Recombinant Proteins
	Uscn Proteins for TREML1

Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005886	plasma membrane	IEA	--
GO:0009986	cell surface	IEA	--
GO:0016021	integral to membrane	NAS	12645956
GO:0031091	platelet alpha granule	IEA	--

TREML1 for ontologies About GeneDecksing

TREML1 Antibody Products:

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	Uscn ELISAs and CLIAs for TREML1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

TREML1 for domains About GeneDecksing

3 InterPro domains/families:

IPR003599 Ig_sub

IPR013783 Ig-like_fold

IPR013106 Ig_V-set

Graphical View of Domain Structure for InterPro Entry Q86YW5

ProtoNet protein and cluster: Q86YW5

2 Blocks protein families:

IPB003599 Immunoglobulin subtype

IPB013106 Immunoglobulin V-set

UniProtKB/Swiss-Prot: TRML1_HUMAN, Q86YW5

Similarity: Contains 1 Ig-like V-type (immunoglobulin-like) domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: TRML1_HUMAN, Q86YW5

Function: Cell surface receptor that may play a role in the innate and adaptive immune response

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TREML1
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		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TREML1 (see all 4) OriGene shRNA RFP: TREML1 OriGene siRNA: TREML1
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Gene Editing
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Cell Line Products:		GenScript Custom overexpressing Cell Line Services for TREML1
		Search LifeMap BioReagents cell lines for TREML1

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TREML1

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004872	receptor activity	--	--
GO:0005515	protein binding	IPI	15128762

TREML1 for ontologies           About GeneDecksing

Animal Models:
     Mouse knock-outs for TREML1: Treml1^tm1Mcvic Treml1^tm1Lex
     5 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Treml1):

cardiovascular system

hematopoietic system

homeostasis/metabolism

immune system

integument

TREML1 for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for TREML1

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

3 Interacting proteins for TREML1 (Q86YW5³ ENSP00000362219⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
PTPN11	Q06124³, ENSP00000340944⁴	I2D: score=2 STRING: ENSP00000340944
PTPN6	P29350³, ENSP00000391592⁴	I2D: score=2 STRING: ENSP00000391592
SIRPA	P78324³	I2D: score=1

About this table

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0019722	calcium-mediated signaling	IDA	15128762
GO:0030168	platelet activation	IEP	15128762
GO:0045087	innate immune response	NAS	12645956

TREML1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for TREML1
Search CenterWatch for drugs/clinical trials and news about TREML1 / TRML1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for TREML1 gene (3 alternative transcripts):

NM_001271807.1 NM_001271808.1 NM_178174.3

Unigene Cluster for TREML1:

Triggering receptor expressed on myeloid cells-like 1

Hs.117331 [show with all ESTs]

Unigene Representative Sequence: NM_178174

4 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000373127(uc011duc.2) ENST00000426005(uc003opx.3) ENST00000437044(uc011dud.2)

ENST00000590581

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat TREML1
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		Browse SwitchGear 3'UTR luciferase reporter plasmids

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for TREML1 (see all 4) OriGene shRNA RFP: TREML1 OriGene siRNA: TREML1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TREML1

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for TREML1 (see all 2) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for TREML1 OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: TREML1 (NM_178174)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for TREML1
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Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for TREML1 Browse OriGene validated miRNA SYBR primer pairs
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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TREML1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TREML1

Additional cDNA sequence:

AF508193.1 AF534822.1 AF534823.1 AY358357.1 BC100944.1 BC100945.1 BC100946.1

3 DOTS entries:

DT.100746791 DT.100746790 DT.40122972

13 AceView cDNA sequences:

BQ023322 AY358357 BX091632 BF439604 AF508193 CK002305 NM_178174 AF534823

AF534822 BU753776 AA699715 AI052571 R02728

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for TREML1 About this scheme

ExUns:	1	^	2	^	3a	·	3b	^	4	^	5	^	6a	·	6b	·	6c
SP1:					-
SP2:					-						-
SP3:			-		-
SP4:

ECgene alternative splicing isoforms for TREML1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

TREML1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACTGAGATGT

About this image

TREML1 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Liver

Liver Lobule

Liver

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See TREML1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for TREML1

SOURCE GeneReport for Unigene cluster: Hs.117331

UniProtKB/Swiss-Prot: TRML1_HUMAN, Q86YW5

Tissue specificity: Detected in platelets, monocytic leukemia and in T-cell leukemia

SABiosciences Custom PCR Arrays for TREML1

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TREML1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of human and mouse.

Orthologs for TREML1 gene from 1/7 species (see all 7) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Treml1^{1 , 5}	triggering receptor expressed on myeloid cells-like more^{1, 5}	76.37(n)¹ 71.24(a)¹		17 (23.99 cM)⁵ 71326¹ NM_027763.1¹ NP_082039.1¹ 48359916⁵

ENSEMBL Gene Tree for TREML1 (if available)
TreeFam Gene Tree for TREML1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 6 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs186989218^1,2		--	41116861(+)	`TGGAGG/TCATCA`	1	--	ds500¹		0	--	--	--	--
rs139251654^1,2		--	41116889(+)	`ACTTCC/TGAAGA`	1	--	ds500¹		0	--	--	--	--
rs189984763^1,2		--	41116919(+)	`GAATCA/CAACTG`	1	--	ds500¹		0	--	--	--	--
rs12209335^1,2	C,H	--	41117076(+)	`CATTAA/GGAGTT`	1	--	ds500¹ ese³		5		NS EA NA	526
rs143162826^1,2		--	41117090(+)	`ACATCA/TTTATT`	1	--	ds500¹		0	--	--	--	--
rs147540499^1,2		--	41117191(+)	`TGAGCA/GTCACT`	1	--	ds500¹		0	--	--	--	--
rs181583933^1,2	C,	--	41117435(+)	`GTGGCA/GTATGT`	2	Y	syn¹		0	--	--	--	--
rs148233882^1,2	C,F,	--	41117439(+)	`CATATG/CTCACA`	2	/T /R	mis¹		1		NA	4552
rs148163083^1,2	C,	--	41117482(+)	`AGGGGA/GCAATG`	2	P S	mis¹		0	--	--	--	--
rs201624028^1,2		--	41117550(+)	`AGGTGA/GTATTG`	2	T I	mis¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for TREML1 (41117080 - 41122075 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for TREML1: --

SABiosciences Cancer Mutation PCR Assays

Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TREML1

DNA2.0 Custom Variant and Variant Library Synthesis for TREML1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

TREML1 for disorders           About GeneDecksing

OMIM gene information: 609714    OMIM disorders: --

4 diseases for TREML1:    About MalaCards

gray platelet syndrome monocytic leukemia t-cell leukemia leukemia

Export disorders for TREML1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for TREML1 gene, integrated from 9 sources (see all 20):
(articles sorted by number of sources associating them with TREML1)

Utopia: connect your pdf to the dynamic
world of online information

The human TREM gene cluster at 6p21.1 encodes both activating and inhibitory single IgV domain receptors and includes NKp44. (PubMed id 12645956)^{1, 2, 3} Allcock R.J.N.... Trowsdale J. (2003)
Initial characterization of TREM-like transcript (TLT)-1: a putative inhibitory receptor within the TREM cluster. (PubMed id 12393607)^{1, 2, 3} Washington A.V.... McVicar D.W. (2002)
The structure of the extracellular domain of triggering receptor expressed on myeloid cells like transcript-1 and evidence for a naturally occurring soluble fragment. (PubMed id 16505478)^{1, 2} Gattis J.L.... Lubkowski J. (2006)
A TREM family member, TLT-1, is found exclusively in the alpha- granules of megakaryocytes and platelets. (PubMed id 15100151)^{1, 2} Washington A.V.... McVicar D.W. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
TREM-like transcript-1, a platelet immunoreceptor tyrosine-based inhibition motif encoding costimulatory immunoreceptor that enhances, rather than inhibits, calcium signaling via SHP-2. (PubMed id 15128762)^{1, 2} Barrow A.D.... Trowsdale J. (2004)
The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)^{1, 2} Mungall A.J.... Beck S. (2003)
The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)^{1, 2} Clark H.F.... Gray A.M. (2003)
Soluble TREM-like transcript-1 regulates leukocyte act ivation and controls microbial sepsis. (PubMed id 22551551)¹ Derive M....Gibot S. (2012)
Proteomic analysis of palmitoylated platelet proteins. (PubMed id 21813449)² Dowal L.... Flaumenhaft R. (2011)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 340205	HGNC: 20434	AceView: TREML1	Ensembl:ENSG00000161911	euGenes: HUgn340205
ECgene: TREML1	H-InvDB: TREML1

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for TREML1	Pharmacogenomics, SNPs, Pathways

Intellectual Property for TREML1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for TREML1 gene:
Search GeneIP for patents involving TREML1

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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	EMD Millipore Custom Antibody & Bulk Services
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	Antibodies for TREML1 (TREML1/TLT-1)		Browse Cell Culture Products
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	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

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	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TREML1
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	Regulatory tfbs in TREML1 promoter
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	RT² qPCR Primer Assay in human, mouse, rat TREML1
	GNC Network for TREML1
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Search Tocris compounds for TREML1

	Browse Sino Biological Proteins and Antibodies
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Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
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	Search for Antibodies for TREML1 at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for TREML1
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Browse ProSpec Recombinant Proteins

TREML1 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for TREML1

	Gene Synthesis
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TREML1

	Browse SwitchGear 3'UTR luciferase reporter plasmids for TREML1
	SwitchGear Promoter luciferase reporter plasmids for TREML1

ThermoFisher Antibodies for TREML1

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat TREML1

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
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The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

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TREML1 Gene

triggering receptor expressed on myeloid cells-like 1

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TREML1 Gene

triggering receptor expressed on myeloid cells-like 1

Aliasesfor TREML1 gene

Summariesfor TREML1 gene

Genomic Viewsfor TREML1 gene

Proteinsfor TREML1 gene

Protein Domains /Familiesfor TREML1 gene

Functionfor TREML1 gene

Pathways & Interactionsfor TREML1 gene

Drugs & Compoundsfor TREML1 gene

Transcriptsfor TREML1 gene

Expression for TREML1 gene

Orthologsfor TREML1 gene

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Genomic Variantsfor TREML1 gene

Disorders / Diseasesfor TREML1 gene

Publicationsfor TREML1 gene

External Searches for TREML1 gene

Genome Databases showing TREML1 gene

Other Databases showing TREML1 gene

Specialized Databases showing TREML1 gene

Intellectual Propertyfor TREML1 gene

Productsfor TREML1 gene

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Aliases
for TREML1 gene

Summaries
for TREML1 gene

Genomic Views
for TREML1 gene

Proteins
for TREML1 gene

Protein Domains /
Families
for TREML1 gene

Function
for TREML1 gene

Pathways & Interactions
for TREML1 gene

Drugs & Compounds
for TREML1 gene

Transcripts
for TREML1 gene

Expression
for TREML1 gene

Orthologs
for TREML1 gene

Paralogs
for TREML1 gene

Genomic Variants
for TREML1 gene

Disorders / Diseases
for TREML1 gene

Publications
for TREML1 gene

Intellectual Property
for TREML1 gene

Products
for TREML1 gene