TRDV1 Gene
protein-coding GIFtS : 23
GCID: GC14 P022604
T cell receptor delta variable 1
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Aliasesfor TRDV1 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section This gene clusters with an RNA geneSubcategory (RNA class): lncRNAQuality score for the ORGUL clustered with this gene is 3 Aliases T Cell Receptor Delta Variable 1 1 2 HDV101S11
External Ids: HGNC: 12262 1 Entrez Gene: 28518 2 Ensembl: ENSG00000211804 7 UniProtKB: A0JD20 4 ORGUL members: NONCODE:n386741 n382136
Export aliases for TRDV1 gene to outside databases Previous GC identifers: GC14U990268 GC14P020554 GC14P021634 GC14P022565 GC14P022572
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Summariesfor TRDV1 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section --
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Genomic Viewsfor TRDV1 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000014.8 NC_018925.1 NT_026437.12 Regulatory elements: Search SABiosciences Regulatory transcription factor binding sites for TRDV1 Other transcription factors Search SABiosciences Chromatin IP Primers for TRDV1 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRDV1
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 14q11 Ensembl cytogenetic band: 14q11.2 HGNC cytogenetic band: 14q11.2 TRDV1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 14 GeneLoc Exon Structure
GeneLoc location for GC14P022604: view genomic region
(about GC identifiers )
Start:
22,564,309 bp from pter
End:
22,564,896 bp from pter
Size:
588 bases
Orientation:
plus strand
ORGUL member locations:Legend (see complete legend)
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Proteinsfor TRDV1 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/TrEMBL: A0JD20 (See
protein sequence )Recommended Name: HDV101S1 Size : 116 amino acids; 13068 DaTRDV1 Protein expression data from MOPED and PaxDb : --
ENSEMBL proteins: ENSP00000452111 Human Recombinant Protein Products for TRDV1: TRDV1 Antibody Products: Assay Products for TRDV1:
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Protein
Domains / Familiesfor TRDV1 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
TRDV1 for domains About GeneDecksing 4 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry A0JD20 ProtoNet protein and cluster: A0JD20
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Functionfor TRDV1 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Animal Models:
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Pathways & Interactionsfor TRDV1 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TRDV1
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Drugs & Compoundsfor TRDV1 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for TRDV1 Search CenterWatch for drugs/clinical trials and news about TRDV1
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Transcriptsfor TRDV1 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section Unigene Cluster for TRDV1:
T cell receptor delta variable 1 Hs.435144 [show with all ESTs ] Unigene Representative Sequence: AK125397 1 Ensembl transcript including schematic representation, and UCSC links where relevant : ENST00000390452 (uc010tmp.1 ) Additional cDNA sequence: AF364079.1 AF364080.1 AF364081.1 AF366486.1 AF366487.1 AF366488.1 AF366489.1 AF366490.1 AF366491.1 AF366492.1 AF366493.1 AF366494.1 AF366495.1 AF366496.1 AF366497.1 AF366498.1 AF366499.1 AF366500.1 AF366501.1 AF366502.1 AF366505.1 AF366506.1 AF366507.1 AF366508.1 AF366509.1 AF366510.1 AF366511.1 AF366512.1 AF366513.1 AF366514.1 AF366515.1 AF366516.1 AF366517.1 AF366518.1 AF366519.1 AK093552.1 AK125397.1
16 DOTS entries : DT.95363549 DT.95070989 DT.97822243 DT.99948856 DT.97818855 DT.97823266 DT.97845700 DT.97845705
DT.97845710 DT.97845717 DT.99927373 DT.40117996 DT.97845709 DT.120744545 DT.95069839 DT.95337473 5 AceView cDNA sequences :
CD691191 AB164056 BI835791 BG620316 CD699871 GeneLoc Exon Structure
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Expression for TRDV1 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section TRDV1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: -- About this image SOURCE GeneReport for Unigene cluster: Hs.435144 SABiosciences Custom PCR Arrays for TRDV1
Primer Products: Browse OriGene genome-wide validated SYBR primer pairs Browse OriGene validated miRNA SYBR primer pairs Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat TRDV1 Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRDV1 Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRDV1
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Orthologsfor TRDV1 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of chordates.
Orthologs for TRDV1 gene from 1/4 species (see all 4 ) About this table
ENSEMBL Gene Tree for TRDV1 (if available)TreeFam Gene Tree for TRDV1 (if available)
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Paralogsfor TRDV1 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for TRDV1 gene TRAV19 2 TRAV38-1 2 TRAV14DV4 2 TRAV38-2DV8 2 TRDV3 2
TRDV1 for paralogs About GeneDecksing 1 Pseudogenes.org Pseudogene for TRDV1 PGOHUM00000248098
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Genomic Variantsfor TRDV1 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section SABiosciences Cancer Mutation PCR Assays
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Disorders
/ Diseasesfor TRDV1 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
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Publicationsfor TRDV1 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for TRDV1 gene integrated from 9 sources : (articles sorted by number of sources associating them with TRDV1) Utopia : connect your pdf to the dynamic world of online information
Genomic organization of the human T-cell antigen-receptor alpha/delta locus. (PubMed id 3186718) 1 , 3 Satyanarayana K....Krangel M.S. (1988) The TCR-delta repertoire in human intestine undergoes characteristic changes during fetal to adult development. (PubMed id 9190911) 1 Holtmeier W....Kagnoff M.F. (1997) Sequence and evolution of the human germline V lambda repertoire. (PubMed id 8951372) 1 Williams S.C....Winter G. (1996)
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External Searches for TRDV1 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing TRDV1 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing TRDV1 gene
(According to HUGE )
About This Section --
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Specialized Databases showing TRDV1 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for TRDV1 Pharmacogenomics, SNPs, Pathways IMGT entry for TRDV1 The international I mM unoG eneT ics information system® specializing in Immunoglobulins (IG), T cell receptors (TR), Major Histocompatibility Complex (MHC) and related proteins of the immune system (RPI) of human and other vertebrate species.
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About This Section Patent Information for TRDV1 gene: Search GeneIP for patents involving TRDV1 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor TRDV1 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TRDV1 Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TRDV1 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRDV1 Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TRDV1 Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRDV1 Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRDV1
Search Tocris compounds for TRDV1
Search ThermoFisher Antibodies for TRDV1
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TRDV1
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