Aliases for TRDMT1 Gene
- TRNA Aspartic Acid Methyltransferase 1 2 3
- DNA (Cytosine-5)-Methyltransferase-Like Protein 2 3 4
- DNA MTase Homolog HsaIIP 3 4
- PUMET 3 4
- DNMT2 3 4
- TRNA Aspartic Acid Methyltransferase 1 Variant 6 3
- TRNA Aspartic Acid Methyltransferase 1 Variant 7 3
- DNA (Cytosine-5-)-Methyltransferase 2 2
- TRNA (Cytosine-5-)-Methyltransferase 3
- DNA Methyltransferase Homolog HsaIIP 4
External Ids for TRDMT1 Gene
Previous HGNC Symbols for TRDMT1 Gene
Previous GeneCards Identifiers for TRDMT1 Gene
This gene encodes a protein responsible for the methylation of aspartic acid transfer RNA, specifically at the cytosine-38 residue in the anticodon loop. This enzyme also possesses residual DNA-(cytosine-C5) methyltransferase activity. While similar in sequence and structure to DNA cytosine methyltransferases, this gene is distinct and highly conserved in its function among taxa. [provided by RefSeq, Jun 2010]
GeneCards Summary for TRDMT1 Gene
TRDMT1 (TRNA Aspartic Acid Methyltransferase 1) is a Protein Coding gene. Among its related pathways are Gene Expression and tRNA modification in the nucleus and cytosol. GO annotations related to this gene include RNA binding and DNA (cytosine-5-)-methyltransferase activity.
UniProtKB/Swiss-Prot for TRDMT1 Gene
Specifically methylates cytosine 38 in the anticodon loop of tRNA(Asp).
Histone methyltransferases (HMTs) are a group of enyzmes that catalyze the transfer of methyl groups from S-adenosylmethionine (SAM) to histones. This occurs predominantly on the side chains of lysine and arginine residues in histones H3 and H4.