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Aliases for TRDJ4 Gene

Aliases for TRDJ4 Gene

  • T Cell Receptor Delta Joining 4 2 3 5

External Ids for TRDJ4 Gene

Previous GeneCards Identifiers for TRDJ4 Gene

  • GC14U990269
  • GC14P020914
  • GC14P021994
  • GC14P022926
  • GC14P022936
  • GC14P022456

Summaries for TRDJ4 Gene

Entrez Gene Summary for TRDJ4 Gene

  • T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016]

GeneCards Summary for TRDJ4 Gene

TRDJ4 (T Cell Receptor Delta Joining 4) is a Protein Coding gene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRDJ4 Gene

Genomics for TRDJ4 Gene

Regulatory Elements for TRDJ4 Gene

Enhancers for TRDJ4 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around TRDJ4 on UCSC Golden Path with GeneCards custom track

Genomic Location for TRDJ4 Gene

Chromosome:
14
Start:
22,455,249 bp from pter
End:
22,455,296 bp from pter
Size:
48 bases
Orientation:
Plus strand

Genomic View for TRDJ4 Gene

Genes around TRDJ4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRDJ4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRDJ4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRDJ4 Gene

Proteins for TRDJ4 Gene

  • Protein details for TRDJ4 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A075B6Z4
    Recommended name:
    Protein TRDJ4
    Protein Accession:
    A0A075B6Z4

    Protein attributes for TRDJ4 Gene

    Size:
    16 amino acids
    Molecular mass:
    1860 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRDJ4 Gene

Post-translational modifications for TRDJ4 Gene

No Post-translational modifications

Other Protein References for TRDJ4 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRDJ4 Gene

Domains & Families for TRDJ4 Gene

Gene Families for TRDJ4 Gene

Protein Domains for TRDJ4 Gene

ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRDJ4: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TRDJ4 Gene

Function for TRDJ4 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRDJ4 Gene

Localization for TRDJ4 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TRDJ4 Gene

Pathways & Interactions for TRDJ4 Gene

SuperPathways for TRDJ4 Gene

No Data Available

Interacting Proteins for TRDJ4 Gene

Gene Ontology (GO) - Biological Process for TRDJ4 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TRDJ4 Gene

Drugs & Compounds for TRDJ4 Gene

No Compound Related Data Available

Transcripts for TRDJ4 Gene

mRNA/cDNA for TRDJ4 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for TRDJ4 Gene

No ASD Table

Relevant External Links for TRDJ4 Gene

GeneLoc Exon Structure for
TRDJ4
ECgene alternative splicing isoforms for
TRDJ4

Expression for TRDJ4 Gene

NURSA nuclear receptor signaling pathways regulating expression of TRDJ4 Gene:

TRDJ4
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for TRDJ4 Gene

Orthologs for TRDJ4 Gene

Evolution for TRDJ4 Gene

ENSEMBL:
Gene Tree for TRDJ4 (if available)
TreeFam:
Gene Tree for TRDJ4 (if available)

No data available for Orthologs for TRDJ4 Gene

Paralogs for TRDJ4 Gene

No data available for Paralogs for TRDJ4 Gene

Variants for TRDJ4 Gene

Relevant External Links for TRDJ4 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRDJ4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRDJ4 Gene

Disorders for TRDJ4 Gene

No disorders were found for TRDJ4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for TRDJ4 Gene

Publications for TRDJ4 Gene

  1. Characterization of a new functional TCR J delta segment in humans. Evidence for a marked conservation of J delta sequences between humans, mice, and sheep. (PMID: 8207230) Davodeau F. … Bonneville M. (J. Immunol. 1994) 2 3 65

Products for TRDJ4 Gene

Sources for TRDJ4 Gene

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