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Aliases for TRDD3 Gene

Aliases for TRDD3 Gene

  • T Cell Receptor Delta Diversity 3 2 3 5
  • TCRD 3

External Ids for TRDD3 Gene

Previous GeneCards Identifiers for TRDD3 Gene

  • GC14U990273
  • GC14P020908
  • GC14P021987
  • GC14P022920
  • GC14P022930
  • GC14P022450

Summaries for TRDD3 Gene

Entrez Gene Summary for TRDD3 Gene

  • T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016]

GeneCards Summary for TRDD3 Gene

TRDD3 (T Cell Receptor Delta Diversity 3) is a Protein Coding gene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRDD3 Gene

Genomics for TRDD3 Gene

Regulatory Elements for TRDD3 Gene

Enhancers for TRDD3 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around TRDD3 on UCSC Golden Path with GeneCards custom track

Genomic Location for TRDD3 Gene

Chromosome:
14
Start:
22,449,113 bp from pter
End:
22,449,125 bp from pter
Size:
13 bases
Orientation:
Plus strand

Genomic View for TRDD3 Gene

Genes around TRDD3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRDD3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRDD3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRDD3 Gene

Proteins for TRDD3 Gene

Post-translational modifications for TRDD3 Gene

No Post-translational modifications

Other Protein References for TRDD3 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRDD3 Gene

Domains & Families for TRDD3 Gene

Gene Families for TRDD3 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRDD3: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TRDD3 Gene

Function for TRDD3 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRDD3 Gene

Localization for TRDD3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TRDD3 Gene

Pathways & Interactions for TRDD3 Gene

SuperPathways for TRDD3 Gene

No Data Available

Interacting Proteins for TRDD3 Gene

Gene Ontology (GO) - Biological Process for TRDD3 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TRDD3 Gene

Drugs & Compounds for TRDD3 Gene

No Compound Related Data Available

Transcripts for TRDD3 Gene

mRNA/cDNA for TRDD3 Gene

(5) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TRDD3 Gene

No ASD Table

Relevant External Links for TRDD3 Gene

GeneLoc Exon Structure for
TRDD3
ECgene alternative splicing isoforms for
TRDD3

Expression for TRDD3 Gene

NURSA nuclear receptor signaling pathways regulating expression of TRDD3 Gene:

TRDD3
No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for TRDD3 Gene

Orthologs for TRDD3 Gene

Evolution for TRDD3 Gene

ENSEMBL:
Gene Tree for TRDD3 (if available)
TreeFam:
Gene Tree for TRDD3 (if available)

No data available for Orthologs for TRDD3 Gene

Paralogs for TRDD3 Gene

No data available for Paralogs for TRDD3 Gene

Variants for TRDD3 Gene

Relevant External Links for TRDD3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRDD3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRDD3 Gene

Disorders for TRDD3 Gene

No disorders were found for TRDD3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for TRDD3 Gene

Publications for TRDD3 Gene

  1. Sequence and organization of the diversity, joining, and constant region genes of the human T-cell delta-chain locus. (PMID: 3413078) Takihara Y. … Mak T.W. (Proc. Natl. Acad. Sci. U.S.A. 1988) 2 3 65
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 65

Products for TRDD3 Gene

Sources for TRDD3 Gene

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