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Aliases for TRDC Gene

Aliases for TRDC Gene

  • T Cell Receptor Delta Constant 2 3
  • TCRD 3

External Ids for TRDC Gene

Previous GeneCards Identifiers for TRDC Gene

  • GC14U990276
  • GC14P020922
  • GC14P022001
  • GC14P022932
  • GC14P003050
  • GC14P022940

Summaries for TRDC Gene

GeneCards Summary for TRDC Gene

TRDC (T Cell Receptor Delta Constant) is a Protein Coding gene. Diseases associated with TRDC include tricuspid valve insufficiency and tricuspid valve disease.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRDC Gene

Genomics for TRDC Gene

Genomic Location for TRDC Gene

Chromosome:
14
Start:
22,422,546 bp from pter
End:
22,466,577 bp from pter
Size:
44,032 bases
Orientation:
Plus strand

Genomic View for TRDC Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for TRDC Gene

No data available for Regulatory Elements for TRDC Gene

Proteins for TRDC Gene

  • Protein details for TRDC Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    B7Z8K6-TRDC_HUMAN
    Recommended name:
    T-cell receptor delta chain C region
    Protein Accession:
    B7Z8K6

    Protein attributes for TRDC Gene

    Size:
    153 amino acids
    Molecular mass:
    17085 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAA61033.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=BAH13992.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for TRDC Gene

neXtProt entry for TRDC Gene

Proteomics data for TRDC Gene at MOPED

Post-translational modifications for TRDC Gene

Other Protein References for TRDC Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRDC Gene

Domains & Families for TRDC Gene

Gene Families for TRDC Gene

Protein Domains for TRDC Gene

Suggested Antigen Peptide Sequences for TRDC Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRDC: view

No data available for UniProtKB/Swiss-Prot for TRDC Gene

Function for TRDC Gene

Gene Ontology (GO) - Molecular Function for TRDC Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003823 antigen binding IBA --
GO:0034987 immunoglobulin receptor binding IBA --
genes like me logo Genes that share ontologies with TRDC: view

miRNA for TRDC Gene

miRTarBase miRNAs that target TRDC

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targets and HOMER Transcription for TRDC Gene

Localization for TRDC Gene

Subcellular locations from UniProtKB/Swiss-Prot for TRDC Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TRDC Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0009897 external side of plasma membrane IBA --
GO:0016021 integral component of membrane IEA --
GO:0042571 immunoglobulin complex, circulating IBA --
GO:0072562 blood microparticle IBA --
genes like me logo Genes that share ontologies with TRDC: view

No data available for Subcellular locations from COMPARTMENTS for TRDC Gene

Pathways & Interactions for TRDC Gene

SuperPathways for TRDC Gene

No Data Available

Interacting Proteins for TRDC Gene

Gene Ontology (GO) - Biological Process for TRDC Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006898 receptor-mediated endocytosis IBA --
GO:0006910 phagocytosis, recognition IBA --
GO:0006911 phagocytosis, engulfment IBA --
GO:0006958 complement activation, classical pathway IBA --
GO:0038095 Fc-epsilon receptor signaling pathway IBA --
genes like me logo Genes that share ontologies with TRDC: view

No data available for Pathways by source and SIGNOR curated interactions for TRDC Gene

Drugs & Compounds for TRDC Gene

No Compound Related Data Available

Transcripts for TRDC Gene

Alternative Splicing Database (ASD) splice patterns (SP) for TRDC Gene

No ASD Table

Relevant External Links for TRDC Gene

GeneLoc Exon Structure for
TRDC
ECgene alternative splicing isoforms for
TRDC

Expression for TRDC Gene

mRNA expression in normal human tissues for TRDC Gene

mRNA differential expression in normal tissues according to GTEx for TRDC Gene

This gene is overexpressed in Whole Blood (x28.4) and Spleen (x7.2).

Protein differential expression in normal tissues from HIPED for TRDC Gene

This gene is overexpressed in Heart (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TRDC Gene



genes like me logo Genes that share expression patterns with TRDC: view

Protein tissue co-expression partners for TRDC Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for TRDC Gene

Orthologs for TRDC Gene

This gene was present in the common ancestor of mammals.

Orthologs for TRDC Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia TRD@ 36
  • 59 (a)
OneToOne
dog
(Canis familiaris)
Mammalia TRDC 36
  • 59 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia TRDC 36
  • 45 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 26 (a)
OneToMany
-- 36
  • 27 (a)
OneToMany
-- 36
  • 24 (a)
OneToMany
-- 36
  • 30 (a)
OneToMany
Species with no ortholog for TRDC:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TRDC Gene

ENSEMBL:
Gene Tree for TRDC (if available)
TreeFam:
Gene Tree for TRDC (if available)

Paralogs for TRDC Gene

(1) SIMAP similar genes for TRDC Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with TRDC: view

No data available for Paralogs for TRDC Gene

Variants for TRDC Gene

Relevant External Links for TRDC Gene

HapMap Linkage Disequilibrium report
TRDC

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRDC Gene

Disorders for TRDC Gene

MalaCards: The human disease database

(2) MalaCards diseases for TRDC Gene - From: DISEASES

Disorder Aliases PubMed IDs
tricuspid valve insufficiency
  • tricuspid valve regurgitation
tricuspid valve disease
  • rheumatic tricuspid valve disease
- elite association
Search TRDC in MalaCards View complete list of genes associated with diseases
genes like me logo Genes that share disorders with TRDC: view

No data available for UniProtKB/Swiss-Prot , Genatlas and External Links for TRDC Gene

Publications for TRDC Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 67
  2. Structure of a human gammadelta T-cell antigen receptor. (PMID: 11459064) Allison T.J. … Garboczi D.N. (Nature 2001) 67
  3. Sequence and organization of the diversity, joining, and constant region genes of the human T-cell delta-chain locus. (PMID: 3413078) Takihara Y. … Mak T.W. (Proc. Natl. Acad. Sci. U.S.A. 1988) 67

Products for TRDC Gene

Sources for TRDC Gene

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