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Aliases for TRD Gene

Aliases for TRD Gene

  • T Cell Receptor Delta Locus 2 3
  • T-Cell Antigen Receptor, Delta Polypeptide 3
  • T-Cell Receptor, Delta (V,D,J,C) 3
  • TCRDV1 3
  • TCRD 3
  • TRD@ 3

External Ids for TRD Gene

Previous HGNC Symbols for TRD Gene

  • TCRD
  • TRD@

Previous GeneCards Identifiers for TRD Gene

  • GC00U990375
  • GC14P022893
  • GC14P023691

Summaries for TRD Gene

GeneCards Summary for TRD Gene

TRD (T Cell Receptor Delta Locus) is a Protein Coding gene. Diseases associated with TRD include subcutaneous panniculitis-like t-cell lymphoma and precursor t-cell acute lymphoblastic leukemia.

Gene Wiki entry for TRD Gene

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRD Gene

Genomics for TRD Gene

Genomic Location for TRD Gene

Chromosome:
14
Start:
22,422,546 bp from pter
End:
22,466,577 bp from pter
Size:
44,032 bases
Orientation:
Plus strand

Genomic View for TRD Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for TRD Gene

No data available for Regulatory Elements for TRD Gene

Proteins for TRD Gene

Post-translational modifications for TRD Gene

No Post-translational modifications

No data available for DME Specific Peptides for TRD Gene

Domains & Families for TRD Gene

Gene Families for TRD Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRD: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TRD Gene

Function for TRD Gene

genes like me logo Genes that share phenotypes with TRD: view

Animal Models for TRD Gene

MGI Knock Outs for TRD:

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , miRNA , Transcription Factor Targets and HOMER Transcription for TRD Gene

Localization for TRD Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TRD Gene

Pathways & Interactions for TRD Gene

SuperPathways for TRD Gene

No Data Available

Interacting Proteins for TRD Gene

Gene Ontology (GO) - Biological Process for TRD Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TRD Gene

Drugs & Compounds for TRD Gene

(6) Drugs for TRD Gene - From: NovoSeek and ClinicalTrials

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Lithium Approved Pharma 206
Quetiapine Approved Pharma Antagonist 400
Venlafaxine Approved Pharma Dual serotonin/noradrenalin re-uptake inhibitor 181
Glucose 6-phosphate Experimental Pharma 0
Lithium Carbonate Pharma 206

(1) Additional Compounds for TRD Gene - From: NovoSeek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
Polyacrylamide
genes like me logo Genes that share compounds with TRD: view

Transcripts for TRD Gene

Alternative Splicing Database (ASD) splice patterns (SP) for TRD Gene

No ASD Table

Relevant External Links for TRD Gene

GeneLoc Exon Structure for
TRD
ECgene alternative splicing isoforms for
TRD

No data available for mRNA/cDNA for TRD Gene

Expression for TRD Gene

No Expression Related Data Available

Primer Products

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for TRD Gene

Orthologs for TRD Gene

This gene was present in the common ancestor of human and mouse.

Orthologs for TRD Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia Tcrd 16
Species with no ortholog for TRD:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

No data available for Evolution for TRD Gene

Paralogs for TRD Gene

No data available for Paralogs for TRD Gene

Variants for TRD Gene

Relevant External Links for TRD Gene

HapMap Linkage Disequilibrium report
TRD
Human Gene Mutation Database (HGMD)
TRD

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRD Gene

Disorders for TRD Gene

MalaCards: The human disease database

(6) MalaCards diseases for TRD Gene - From: Orphanet, NovoSeek, and GeneCards

- elite association
Search TRD in MalaCards View complete list of genes associated with diseases

Relevant External Links for TRD

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TRD
genes like me logo Genes that share disorders with TRD: view

No data available for UniProtKB/Swiss-Prot and Genatlas for TRD Gene

Publications for TRD Gene

  1. T-cell abnormalities are present at high frequencies in patients with hypereosinophilic syndrome. (PMID: 19734416) Helbig G. … Kyrcz-Krzemien S. (Haematologica 2009) 23 67
  2. Diversity of T-cell receptor gene rearrangements in South Indian patients with common acute lymphoblastic leukemia. (PMID: 19801787) Sudhakar N. … Rajkumar T. (Iran J Immunol 2009) 23 67
  3. Characteristics of T-cell large granular lymphocyte proliferations associated with neutropenia and inflammatory arthropathy. (PMID: 18474096) Prochorec-Sobieszek M. … Maryniak R. (Arthritis Res. Ther. 2008) 23 67
  4. Subcutaneous panniculitis-like T-cell lymphoma: a clinicopathologic, immunophenotypic, and molecular study of 22 Asian cases according to WHO-EORTC classification. (PMID: 18708940) Kong Y.Y. … Shi D.R. (Am. J. Surg. Pathol. 2008) 23 67
  5. T cell receptor genotyping and HOXA/TLX1 expression define three T lymphoblastic lymphoma subsets which might affect clinical outcome. (PMID: 18245528) Baleydier F. … Macintyre E. (Clin. Cancer Res. 2008) 23 67

Products for TRD Gene

Sources for TRD Gene

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