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Aliases for TRBV6-1 Gene

Aliases for TRBV6-1 Gene

  • T Cell Receptor Beta Variable 6-1 2 3 5
  • T-Cell Receptor Beta Chain V Region C5 -Like, V_segment Translation Product 3
  • T-Cell Receptor Beta Chain V Region C5 -Like 2
  • V_segment Translation Product 3
  • TCRBV13S3 3
  • TCRBV6S1 3
  • TRBV61 3

External Ids for TRBV6-1 Gene

Previous GeneCards Identifiers for TRBV6-1 Gene

  • GC07U990229
  • GC07P141358
  • GC07P141435
  • GC07P141482
  • GC07P141689
  • GC07P142164
  • GC07P142186
  • GC07P142316
  • GC07P142352
  • GC07P142410
  • GC07P142463
  • GC07P142583
  • GC07P142674
  • GC07P142742
  • GC07P142804
  • GC07P142603
  • GC07P142837
  • GC07P143000
  • GC07P143148

Summaries for TRBV6-1 Gene

GeneCards Summary for TRBV6-1 Gene

TRBV6-1 (T Cell Receptor Beta Variable 6-1) is a Protein Coding gene. An important paralog of this gene is TRBV6-8.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRBV6-1 Gene

Genomics for TRBV6-1 Gene

Regulatory Elements for TRBV6-1 Gene

Enhancers for TRBV6-1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07F142323 1.2 Ensembl ENCODE 0.8 -4.2 -4227 0.7 CTCF TEAD4 KLF17 ZIC2 RAD21 HIC1 GLIS2 ZBTB48 PATZ1 KLF8 TRBV5-1 TRBV6-1
GH07F142328 1.2 Ensembl ENCODE 0.8 0.0 -49 0.3 SMARCA4 POLR2A TRBV6-1 TRBV5-1
GH07F142327 0.2 ENCODE 0.8 -0.5 -466 0.2 SMARCA4 POLR2A TRBV6-1 TRBV5-1
GH07F142326 0.2 ENCODE 0.8 -1.5 -1500 0.5 ZNF362 JUND ATF3 NBN FOS ATF2 TRBV6-1 TRBV5-1
GH07F142321 0.6 Ensembl ENCODE 0.4 -7.3 -7291 1.2 ZNF316 TRBV4-1 TRBV5-1 TRBV6-1
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around TRBV6-1 on UCSC Golden Path with GeneCards custom track

Genomic Location for TRBV6-1 Gene

142,328,297 bp from pter
142,328,786 bp from pter
490 bases
Plus strand

Genomic View for TRBV6-1 Gene

Genes around TRBV6-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRBV6-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRBV6-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRBV6-1 Gene

Proteins for TRBV6-1 Gene

  • Protein details for TRBV6-1 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    Protein TRBV6-1
    Protein Accession:
    Secondary Accessions:
    • A0A0B4J1U5
    • A0A586

    Protein attributes for TRBV6-1 Gene

    114 amino acids
    Molecular mass:
    12632 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRBV6-1 Gene

Post-translational modifications for TRBV6-1 Gene

No Post-translational modifications

Other Protein References for TRBV6-1 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRBV6-1 Gene

Domains & Families for TRBV6-1 Gene

Gene Families for TRBV6-1 Gene

Protein Domains for TRBV6-1 Gene

Suggested Antigen Peptide Sequences for TRBV6-1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRBV6-1: view

No data available for UniProtKB/Swiss-Prot for TRBV6-1 Gene

Function for TRBV6-1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRBV6-1 Gene

Localization for TRBV6-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TRBV6-1 Gene

Pathways & Interactions for TRBV6-1 Gene

SuperPathways for TRBV6-1 Gene

No Data Available

Interacting Proteins for TRBV6-1 Gene

Gene Ontology (GO) - Biological Process for TRBV6-1 Gene


No data available for Pathways by source and SIGNOR curated interactions for TRBV6-1 Gene

Transcripts for TRBV6-1 Gene

mRNA/cDNA for TRBV6-1 Gene

(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TRBV6-1 Gene

No ASD Table

Relevant External Links for TRBV6-1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TRBV6-1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TRBV6-1 Gene

mRNA differential expression in normal tissues according to GTEx for TRBV6-1 Gene

This gene is overexpressed in Whole Blood (x29.8), Spleen (x5.9), and Small Intestine - Terminal Ileum (x4.4).
genes like me logo Genes that share expression patterns with TRBV6-1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for TRBV6-1 Gene

Orthologs for TRBV6-1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TRBV6-1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia -- 35
  • 66 (a)
-- 35
  • 64 (a)
-- 35
  • 63 (a)
-- 35
  • 63 (a)
-- 35
  • 63 (a)
-- 35
  • 63 (a)
-- 35
  • 62 (a)
-- 35
  • 62 (a)
-- 35
  • 61 (a)
-- 35
  • 57 (a)
-- 35
  • 56 (a)
-- 35
  • 55 (a)
-- 35
  • 55 (a)
-- 35
  • 53 (a)
TRB@ 35
  • 48 (a)
(Monodelphis domestica)
Mammalia -- 35
  • 51 (a)
-- 35
  • 42 (a)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 38 (a)
(Gallus gallus)
Aves -- 35
  • 37 (a)
-- 35
  • 30 (a)
-- 35
  • 29 (a)
(Anolis carolinensis)
Reptilia -- 35
  • 36 (a)
-- 35
  • 25 (a)
Species where no ortholog for TRBV6-1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TRBV6-1 Gene

Gene Tree for TRBV6-1 (if available)
Gene Tree for TRBV6-1 (if available)

Paralogs for TRBV6-1 Gene

genes like me logo Genes that share paralogs with TRBV6-1: view

Variants for TRBV6-1 Gene

Relevant External Links for TRBV6-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRBV6-1 Gene

Disorders for TRBV6-1 Gene

Relevant External Links for TRBV6-1

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for TRBV6-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TRBV6-1 Gene

Publications for TRBV6-1 Gene

  1. The complete 685-kilobase DNA sequence of the human beta T cell receptor locus. (PMID: 8650574) Rowen L. … Hood L. (Science 1996) 2 3 64
  2. In angioimmunoblastic T-cell lymphoma, neoplastic T cells may be a minor cell population. A molecular single-cell and immunohistochemical study. (PMID: 15480765) Willenbrock K. … Hansmann M.L. (Virchows Arch. 2005) 3 64
  3. Genetic epidemiology of juvenile idiopathic arthritis. (PMID: 12195624) FA … Smerdel A. (Scand. J. Rheumatol. 2002) 46 64
  4. The genomic structure of human V beta 6 T cell antigen receptor genes. (PMID: 1660526) Li Y. … Posnett D.N. (J. Exp. Med. 1991) 3 64
  5. Low frequency of somatic mutation in beta-chain variable region genes of human T-cell receptors. (PMID: 3865189) Ikuta K. … Honjo T. (Proc. Natl. Acad. Sci. U.S.A. 1985) 3 64

Products for TRBV6-1 Gene

Sources for TRBV6-1 Gene

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