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Aliases for TRBV5-4 Gene

Aliases for TRBV5-4 Gene

  • T Cell Receptor Beta Variable 5-4 2 3 5
  • V_segment Translation Product 3
  • TCRBV5S6A3N2T 3
  • TCRBV5S4 3
  • TRBV54 3

External Ids for TRBV5-4 Gene

Previous GeneCards Identifiers for TRBV5-4 Gene

  • GC07U990234
  • GC07P141515
  • GC07P141593
  • GC07P141596
  • GC07P141639
  • GC07P141833
  • GC07P141835
  • GC07P141840
  • GC07P141951
  • GC07M142168
  • GC07P142685
  • GC07P142954
  • GC07P143099
  • GC07P143254

Summaries for TRBV5-4 Gene

GeneCards Summary for TRBV5-4 Gene

TRBV5-4 (T Cell Receptor Beta Variable 5-4) is a Protein Coding gene. An important paralog of this gene is TRBV5-6.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRBV5-4 Gene

Genomics for TRBV5-4 Gene

Regulatory Elements for TRBV5-4 Gene

Enhancers for TRBV5-4 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07F142458 0.2 Ensembl 0.8 -3.1 -3115 2.0 TRBV5-4 TRBV7-4
GH07F142459 0.2 Ensembl 0.8 -4.8 -4816 0.2 TRBV5-4 TRBV7-4
GH07F142461 0.2 Ensembl 0.8 -0.3 -264 2.7 TRBV5-4 TRBV7-4
GH07F142454 0.2 Ensembl 0.4 -7.7 -7676 0.7 TRBV7-4 TRBV5-4
GH07F142455 0.2 Ensembl 0.4 -7.0 -7016 0.2 TRBV7-4 TRBV5-4
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TRBV5-4 on UCSC Golden Path with GeneCards custom track

Genomic Location for TRBV5-4 Gene

142,462,916 bp from pter
142,463,581 bp from pter
666 bases
Plus strand

Genomic View for TRBV5-4 Gene

Genes around TRBV5-4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRBV5-4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRBV5-4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRBV5-4 Gene

Proteins for TRBV5-4 Gene

  • Protein details for TRBV5-4 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    Protein TRBV5-4
    Protein Accession:

    Protein attributes for TRBV5-4 Gene

    114 amino acids
    Molecular mass:
    12518 Da
    Quaternary structure:
    No Data Available
  • Protein details for TRBV5-4 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    Protein TRBV5-4
    Protein Accession:

    Protein attributes for TRBV5-4 Gene

    114 amino acids
    Molecular mass:
    12426 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRBV5-4 Gene

Post-translational modifications for TRBV5-4 Gene

No Post-translational modifications

Other Protein References for TRBV5-4 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRBV5-4 Gene

Domains & Families for TRBV5-4 Gene

Gene Families for TRBV5-4 Gene

Protein Domains for TRBV5-4 Gene

Suggested Antigen Peptide Sequences for TRBV5-4 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRBV5-4: view

No data available for UniProtKB/Swiss-Prot for TRBV5-4 Gene

Function for TRBV5-4 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRBV5-4 Gene

Localization for TRBV5-4 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TRBV5-4 Gene

Pathways & Interactions for TRBV5-4 Gene

SuperPathways for TRBV5-4 Gene

No Data Available

Interacting Proteins for TRBV5-4 Gene

Gene Ontology (GO) - Biological Process for TRBV5-4 Gene


No data available for Pathways by source and SIGNOR curated interactions for TRBV5-4 Gene

Transcripts for TRBV5-4 Gene

mRNA/cDNA for TRBV5-4 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for TRBV5-4 Gene

No ASD Table

Relevant External Links for TRBV5-4 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TRBV5-4 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TRBV5-4 Gene

mRNA differential expression in normal tissues according to GTEx for TRBV5-4 Gene

This gene is overexpressed in Whole Blood (x24.8) and Pancreas (x8.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from MaxQB and MOPED for TRBV5-4 Gene

genes like me logo Genes that share expression patterns with TRBV5-4: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for TRBV5-4 Gene

Orthologs for TRBV5-4 Gene

This gene was present in the common ancestor of mammals.

Orthologs for TRBV5-4 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia TRBV5-4 35
  • 79 (a)
(Monodelphis domestica)
Mammalia -- 35
  • 47 (a)
-- 35
  • 45 (a)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 40 (a)
Species where no ortholog for TRBV5-4 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TRBV5-4 Gene

Gene Tree for TRBV5-4 (if available)
Gene Tree for TRBV5-4 (if available)

Paralogs for TRBV5-4 Gene

Variants for TRBV5-4 Gene

Relevant External Links for TRBV5-4 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRBV5-4 Gene

Disorders for TRBV5-4 Gene

Relevant External Links for TRBV5-4

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for TRBV5-4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TRBV5-4 Gene

Publications for TRBV5-4 Gene

  1. The complete 685-kilobase DNA sequence of the human beta T cell receptor locus. (PMID: 8650574) Rowen L. … Hood L. (Science 1996) 2 3 64
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64
  3. Nucleotide sequence analysis of 77.7 kb of the human V beta T-cell receptor gene locus: direct primer-walking using cosmid template DNAs. (PMID: 8020962) Slightom J.L. … Hood L. (Genomics 1994) 3 64

Products for TRBV5-4 Gene

Sources for TRBV5-4 Gene

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