TRBV4-2 Gene
protein-coding GIFtS : 18 GCID: GC07 P142676
T cell receptor beta variable 4-2
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Aliasesfor TRBV4-2 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases T Cell Receptor Beta Variable 4-2 1 2 TCRBV7S3A2T1 2 4 TCRBV4S21 2 TRBV421 2 TCRBV7S3A22
Export aliases for TRBV4-2 gene to outside databases Previous GC identifers: GC07U990239 GC07P141375 GC07P141453 GC07P141454 GC07P141498 GC07P141692 GC07P142166 GC07P142188 GC07P142310 GC07P142383 GC07P142412 GC07P142465 GC07P142585
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Summariesfor TRBV4-2 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section
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Genomic Viewsfor TRBV4-2 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,miRBase ,UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section Regulatory elements: Search SABiosciences Regulatory transcription factor binding sites for TRBV4-2 Other transcription factors Search SABiosciences Chromatin IP Primers for TRBV4-2 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRBV4-2
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 7q34 Ensembl cytogenetic band: 7q34 HGNC cytogenetic band: 7q34 TRBV4-2 Gene in genomic location: bands according to Ensembl, locations according to
Entrez Gene Ensembl GeneLoc information about chromosome 7 GeneLoc Exon Structure
GeneLoc location for GC07P142676: view genomic region
(about GC identifiers )
Start: 142,045,252 bp from pter End:
142,045,816 bp from pter
Size: 565 bases Orientation:
plus strand
1 alternative location : Chr 7+,CRA_TCAG 141,383,565-141,384,018
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Proteinsfor TRBV4-2 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/TrEMBL: A0A539 See
protein sequence )Recommended Name: Size : 114 amino acids; 12890 DaTRBV4-2 Protein expression data from MOPED and PaxDb : About this image
ENSEMBL proteins: ENSP00000374915 Human Recombinant Protein Products for TRBV4-2: TRBV4-2 Antibody Products: Assay Products for TRBV4-2:
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Protein
Domains /for TRBV4-2 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section About GeneDecksing 3 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry A0A539 ProtoNet protein and cluster: A0A539
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Functionfor TRBV4-2 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Animal Models:
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Pathways & Interactionsfor TRBV4-2 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TRBV4-2
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Drugs & Compoundsfor TRBV4-2 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for TRBV4-2 TRBV4-2
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Transcriptsfor TRBV4-2 gene (Secondary structures according to
fRNAdb ,Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC , GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,EMD Millipore ,
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section 1 Ensembl transcript including schematic representation, and UCSC links where relevant : ENST00000390392 (uc003vxp.4 ) 4 AceView cDNA sequences :
BV171788 BV199373 AA917779 AI243564 GeneLoc Exon Structure
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Expression for TRBV4-2 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section TRBV4-2 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: -- About this image See TRBV4-2 Protein Expression from SPIRE MOPED and PaxDB SABiosciences Custom PCR Arrays for TRBV4-2
Primer Browse OriGene genome-wide validated SYBR primer pairs Browse OriGene validated miRNA SYBR primer pairs Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat TRBV4-2 Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRBV4-2 Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRBV4-2
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Orthologsfor TRBV4-2 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
ENSEMBL Gene Tree for TRBV4-2 (if available)TreeFam Gene Tree for TRBV4-2 (if available)
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Paralogsfor TRBV4-2 gene (Paralogs according to
1 HomoloGene ,2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for TRBV4-2 gene TRBV11-1 2 TRBV19 2 TRBV3-1 2 TRBV9 2 TRBV7-3 2 TRBV6-5 2 TRBV21OR9-2 2 TRBV7-4 2 TRBV6-6 2 TRBV25-1 2 TRBV23OR9-2 2 TRBV5-1 2 TRBV4-1 2 TRBV7-1 2 TRBV6-8 2 TRBV5-7 2 TRBV6-1 2 TRBV10-1 2 TRBV7-7 2 TRBV23-1 2 TRBV5-3 2 TRBV28 2 TRBV6-4 2 TRBV2 2 TRBV6-7 2 TRBV27 2 TRBV5-5 2 TRBV5-6 2 TRBV7-6 2 TRBV25OR9-2 2 TRBV10-2 2 TRBV5-4 2 TRBV24-1 2 TRBV7-8 2 TRBV6-9 2 About GeneDecksing 2 Pseudogenes.org Pseudogenes for TRBV4-2 PGOHUM00000233603 PGOHUM00000261642
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Genomic Variantsfor TRBV4-2 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section SABiosciences Cancer Mutation PCR Assays
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Disorders
/ Diseasesfor TRBV4-2 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
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Publicationsfor TRBV4-2 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for TRBV4-2 gene integrated from 9 sources :(articles sorted by number of sources associating them with TRBV4-2) Utopia : connect your pdf to the dynamic
The complete 685-kilobase DNA sequence of the human beta T cell receptor locus. (PubMed id 8650574) 1 , 3(1996) A genetically determined insertion/deletion related p olymorphism in human T cell receptor beta chain (TCRB) includes functional vari able gene segments. (PubMed id 7931073) 1 (1994)
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External Searches for TRBV4-2 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing TRBV4-2 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing TRBV4-2 gene
(According to HUGE )
About This Section --
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Specialized Databases showing TRBV4-2 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description PharmGKB entry for TRBV4-2 Pharmacogenomics, SNPs, Pathways IMGT entry for TRBV4-2The international I mM unoG eneT ics information system® specializing in Immunoglobulins (IG), T cell receptors (TR), Major Histocompatibility Complex (MHC) and related proteins of the immune system (RPI) of human and other vertebrate species.
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About This Section Patent Information for TRBV4-2 gene: TRBV4-2 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor TRBV4-2 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TRBV4-2 Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TRBV4-2 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRBV4-2 Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TRBV4-2 Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRBV4-2 Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRBV4-2
Search Tocris compounds for TRBV4-2
Search ThermoFisher Antibodies for TRBV4-2
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TRBV4-2
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Products for TRBV4-2
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