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Aliases for TRBV4-1 Gene

Aliases for TRBV4-1 Gene

  • T-Cell Receptor Beta Variable 4-1 2 5
  • T Cell Receptor Beta Variable 4-1 2 3
  • T-Cell Receptor Beta Chain V Region 86T1 3
  • V_segment Translation Product 3
  • TCRBV7S1A1N2T 3
  • BV07S1J2.7 3
  • TCRBV4S1 3
  • TRBV41 3

External Ids for TRBV4-1 Gene

Previous GeneCards Identifiers for TRBV4-1 Gene

  • GC07U990240
  • GC07P141343
  • GC07P141420
  • GC07P141471
  • GC07P141659
  • GC07P142162
  • GC07P142184
  • GC07P142318
  • GC07P142357
  • GC07P142408
  • GC07P142455
  • GC07P142581
  • GC07P142672
  • GC07P142740
  • GC07P142802
  • GC07P142601
  • GC07P142833
  • GC07P142994
  • GC07P143146
  • GC07P143346

Summaries for TRBV4-1 Gene

GeneCards Summary for TRBV4-1 Gene

TRBV4-1 (T-Cell Receptor Beta Variable 4-1) is a Protein Coding gene. An important paralog of this gene is TRBV4-2.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRBV4-1 Gene

Genomics for TRBV4-1 Gene

Regulatory Elements for TRBV4-1 Gene

Enhancers for TRBV4-1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07G142312 1 Ensembl ENCODE dbSUPER 17.4 +0.6 566 2.5 ZNF263 CTCF PRDM10 RAD21 TRBV4-1 TRBV5-1
GH07G142302 0.4 dbSUPER 12.9 -10.3 -10263 1.1 CTCF JUND TRBV4-1 TRY2P TRBV2 TRBV3-1
GH07G142321 0.8 ENCODE dbSUPER 5.9 +7.0 7003 0.2 CTCF ZNF316 ZNF3 RAD21 MAFK TRBV4-1 TRBV5-1
GH07G142320 0.5 Ensembl dbSUPER 4.8 +7.8 7817 0.4 TRBV4-1 TRBV5-1 TRBV6-1
GH07G142313 0.6 ENCODE dbSUPER 0.7 -0.7 -711 0.0 ZNF263 TRBV3-1 TRBV4-1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TRBV4-1 on UCSC Golden Path with GeneCards custom track

Genomic Location for TRBV4-1 Gene

142,313,184 bp from pter
142,313,666 bp from pter
483 bases
Plus strand

Genomic View for TRBV4-1 Gene

Genes around TRBV4-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRBV4-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRBV4-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRBV4-1 Gene

Proteins for TRBV4-1 Gene

  • Protein details for TRBV4-1 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    T-cell receptor beta variable 4-1
    Protein Accession:

    Protein attributes for TRBV4-1 Gene

    114 amino acids
    Molecular mass:
    12918 Da
    Quaternary structure:
    No Data Available
  • Protein details for TRBV4-1 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    Recommended name:
    T-cell receptor beta variable 4-1
    Protein Accession:
    Secondary Accessions:
    • A0A075B6L4

    Protein attributes for TRBV4-1 Gene

    114 amino acids
    Molecular mass:
    12859 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRBV4-1 Gene

Post-translational modifications for TRBV4-1 Gene

No Post-translational modifications

Other Protein References for TRBV4-1 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRBV4-1 Gene

Domains & Families for TRBV4-1 Gene

Gene Families for TRBV4-1 Gene

Protein Domains for TRBV4-1 Gene

Suggested Antigen Peptide Sequences for TRBV4-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRBV4-1: view

No data available for UniProtKB/Swiss-Prot for TRBV4-1 Gene

Function for TRBV4-1 Gene

Animal Model Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRBV4-1 Gene

Localization for TRBV4-1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TRBV4-1 Gene

Pathways & Interactions for TRBV4-1 Gene

SuperPathways for TRBV4-1 Gene

No Data Available

Interacting Proteins for TRBV4-1 Gene

Gene Ontology (GO) - Biological Process for TRBV4-1 Gene


No data available for Pathways by source and SIGNOR curated interactions for TRBV4-1 Gene

Drugs & Compounds for TRBV4-1 Gene

No Compound Related Data Available

Transcripts for TRBV4-1 Gene

mRNA/cDNA for TRBV4-1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TRBV4-1 Gene

No ASD Table

Relevant External Links for TRBV4-1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TRBV4-1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TRBV4-1 Gene

mRNA differential expression in normal tissues according to GTEx for TRBV4-1 Gene

This gene is overexpressed in Whole Blood (x30.7) and Spleen (x6.0).
genes like me logo Genes that share expression patterns with TRBV4-1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRBV4-1 Gene

Orthologs for TRBV4-1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TRBV4-1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia -- 35
  • 57 (a)
(Canis familiaris)
Mammalia -- 35
  • 57 (a)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 41 (a)
(Monodelphis domestica)
Mammalia -- 35
  • 40 (a)
(Gallus gallus)
Aves -- 35
  • 26 (a)
-- 35
  • 20 (a)
-- 35
  • 19 (a)
(Anolis carolinensis)
Reptilia -- 35
  • 29 (a)
-- 35
  • 23 (a)
Species where no ortholog for TRBV4-1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TRBV4-1 Gene

Gene Tree for TRBV4-1 (if available)
Gene Tree for TRBV4-1 (if available)

Paralogs for TRBV4-1 Gene

Variants for TRBV4-1 Gene

Relevant External Links for TRBV4-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRBV4-1 Gene

Disorders for TRBV4-1 Gene

No disorders were found for TRBV4-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for TRBV4-1 Gene

Publications for TRBV4-1 Gene

  1. The complete 685-kilobase DNA sequence of the human beta T cell receptor locus. (PMID: 8650574) Rowen L. … Hood L. (Science 1996) 2 3 64
  2. In angioimmunoblastic T-cell lymphoma, neoplastic T cells may be a minor cell population. A molecular single-cell and immunohistochemical study. (PMID: 15480765) Willenbrock K. … Hansmann M.L. (Virchows Arch. 2005) 3 64
  3. A genetically determined insertion/deletion related polymorphism in human T cell receptor beta chain (TCRB) includes functional variable gene segments. (PMID: 7931073) Zhao T.M. … Robinson M.A. (J. Exp. Med. 1994) 3 64

Products for TRBV4-1 Gene

Sources for TRBV4-1 Gene

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