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Aliases for TRBV28 Gene

Aliases for TRBV28 Gene

  • T Cell Receptor Beta Variable 28 2 3
  • V_segment Translation Product 3
  • TCRBV28S1 3
  • TCRBV3S1 3
  • TRBC1 4

External Ids for TRBV28 Gene

Previous GeneCards Identifiers for TRBV28 Gene

  • GC07U990182
  • GC07P141792
  • GC07P141868
  • GC07P141914
  • GC07P142108
  • GC07P142429
  • GC07P142453
  • GC07P142492
  • GC07P142649
  • GC07P142719
  • GC07P142779

Summaries for TRBV28 Gene

GeneCards Summary for TRBV28 Gene

TRBV28 (T Cell Receptor Beta Variable 28) is a Protein Coding gene. An important paralog of this gene is TRBV2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRBV28 Gene

Genomics for TRBV28 Gene

Genomic Location for TRBV28 Gene

142,720,660 bp from pter
142,793,255 bp from pter
72,596 bases
Plus strand

Genomic View for TRBV28 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TRBV28 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRBV28 Gene

No data available for Regulatory Elements for TRBV28 Gene

Proteins for TRBV28 Gene

  • Protein details for TRBV28 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    T-cell receptor beta-1 chain C region
    Protein Accession:
    Secondary Accessions:
    • A0A5B8
    • A6NH51

    Protein attributes for TRBV28 Gene

    177 amino acids
    Molecular mass:
    19899 Da
    Quaternary structure:
    No Data Available
    • Sequence=CAA25134.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for TRBV28 Gene

neXtProt entry for TRBV28 Gene

Proteomics data for TRBV28 Gene at MOPED

Post-translational modifications for TRBV28 Gene

Other Protein References for TRBV28 Gene

ENSEMBL proteins:
Reactome Protein details:

No data available for DME Specific Peptides for TRBV28 Gene

Domains for TRBV28 Gene

Gene Families for TRBV28 Gene

Protein Domains for TRBV28 Gene

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 Ig-like (immunoglobulin-like) domain.
  • Contains 1 Ig-like (immunoglobulin-like) domain.
genes like me logo Genes that share domains with TRBV28: view

No data available for Suggested Antigen Peptide Sequences for TRBV28 Gene

Function for TRBV28 Gene

Gene Ontology (GO) - Molecular Function for TRBV28 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with TRBV28: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TRBV28 Gene

Localization for TRBV28 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TRBV28 Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TRBV28 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane --
GO:0016020 membrane --
GO:0016021 integral component of membrane --
genes like me logo Genes that share ontologies with TRBV28: view

No data available for Subcellular locations from COMPARTMENTS for TRBV28 Gene

Pathways for TRBV28 Gene

SuperPathways for TRBV28 Gene

No Data Available

Interacting Proteins for TRBV28 Gene

Selected Interacting proteins: P01850-TRBC1_HUMAN for TRBV28 Gene via MINT UniProtKB I2D

Gene Ontology (GO) - Biological Process for TRBV28 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006955 immune response --
GO:0031295 T cell costimulation --
GO:0050776 regulation of immune response --
GO:0050852 T cell receptor signaling pathway --
genes like me logo Genes that share ontologies with TRBV28: view

No data available for Pathways by source for TRBV28 Gene

Transcripts for TRBV28 Gene

mRNA/cDNA for TRBV28 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for TRBV28 Gene

No ASD Table

Relevant External Links for TRBV28 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TRBV28 Gene

mRNA expression in normal human tissues for TRBV28 Gene

mRNA differential expression in normal tissues according to GTEx for TRBV28 Gene

This gene is overexpressed in Whole Blood (34.2) and Spleen (4.6).

Protein differential expression in normal tissues for TRBV28 Gene

This gene is overexpressed in Tlymphocyte (51.6), CD4 Tcells (8.8), and Peripheral blood mononuclear cells (7.0).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for TRBV28 Gene

genes like me logo Genes that share expressions with TRBV28: view

Expression partners for TRBV28 Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for TRBV28 Gene

Orthologs for TRBV28 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TRBV28 Gene

Organism Taxonomy Gene Similarity Type Details
(Gallus gallus)
Aves -- 36
  • 30 (a)
-- 36
  • 35 (a)
-- 36
  • 28 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 21 (a)
-- 36
  • 29 (a)
Species with no ortholog for TRBV28:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TRBV28 Gene

Gene Tree for TRBV28 (if available)
Gene Tree for TRBV28 (if available)

Paralogs for TRBV28 Gene

genes like me logo Genes that share paralogs with TRBV28: view

Variants for TRBV28 Gene

Relevant External Links for TRBV28 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for TRBV28 Gene

Disorders for TRBV28 Gene

No disorders were found for TRBV28 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for TRBV28 Gene

Publications for TRBV28 Gene

  1. The complete 685-kilobase DNA sequence of the human beta T cell receptor locus. (PMID: 8650574) Rowen L. … Hood L. (Science 1996) 2 3 4
  2. Sequence and evolution of the human T-cell antigen receptor beta- chain genes. (PMID: 3860845) Tunnacliffe A. … Rabbitts T.H. (Proc. Natl. Acad. Sci. U.S.A. 1985) 4
  3. A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains. (PMID: 6336315) Yanagi Y. … Mak T.W. (Nature 1984) 4
  4. A structural basis for immunodominant human T cell receptor recognition. (PMID: 12796775) Stewart-Jones G.B.E. … Jones E.Y. (Nat. Immunol. 2003) 4
  5. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 4

Products for TRBV28 Gene

Sources for TRBV28 Gene

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