TRBV27 Gene
protein-coding GIFtS : 20
GCID: GC07 P142647
T cell receptor beta variable 27
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Aliasesfor TRBV27 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases T Cell Receptor Beta Variable 27 1 2 TCRBV14S11 2 TCRBV27S11 2
Export aliases for TRBV27 gene to outside databases Previous GC identifers: GC07U990183 GC07P141786 GC07P141863 GC07P141904 GC07P141910 GC07P142102 GC07Pg41794 GC07P142425 GC07P142445 GC07P142490
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Summariesfor TRBV27 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
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Genomic Viewsfor TRBV27 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000007.13 NC_018918.1 NT_007914.15 NT_079596.2 Regulatory elements: Search SABiosciences Regulatory transcription factor binding sites for TRBV27 Other transcription factors Search SABiosciences Chromatin IP Primers for TRBV27 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRBV27
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 7q34 Ensembl cytogenetic band: 7q34 HGNC cytogenetic band: 7q34 TRBV27 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 7 GeneLoc Exon Structure
GeneLoc location for GC07P142647: view genomic region
(about GC identifiers )
Start:
142,423,173 bp from pter
End:
142,423,688 bp from pter
Size:
516 bases
Orientation:
plus strand
1 alternative location : Chr 7+,CRA_TCAG 141,794,525-141,794,997
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Proteinsfor TRBV27 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB: --TRBV27 Protein expression data from MOPED and PaxDb : About this image
ENSEMBL proteins: ENSP00000374922 Human Recombinant Protein Products: Antibody Products for TRBV27: Assay Products for TRBV27:
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Protein
Domains / Familiesfor TRBV27 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
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Functionfor TRBV27 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section
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Pathways & Interactionsfor TRBV27 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TRBV27
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Drugs & Compoundsfor TRBV27 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for TRBV27 Search CenterWatch for drugs/clinical trials and news about TRBV27
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Transcriptsfor TRBV27 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section Unigene Cluster for TRBV27:
T cell receptor beta variable 27 Hs.511522 [show with all ESTs ] Unigene Representative Sequence: AK093303 1 Ensembl transcript including schematic representation, and UCSC links where relevant : ENST00000390399 Additional cDNA sequence: AB305921.1 AB305956.1 AB305973.1 AB305998.1 AB306208.1 AF272742.1 AK093303.1
5 DOTS entries : DT.100688193 DT.121076595 DT.92456575 DT.75127395 DT.121076097
2 AceView cDNA sequences :
AX748042 AK093303 GeneLoc Exon Structure
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Expression for TRBV27 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section TRBV27 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: ATGGTGCACA
About this image See TRBV27 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for TRBV27 SOURCE GeneReport for Unigene cluster: Hs.511522 SABiosciences Custom PCR Arrays for TRBV27 Primer Products: Browse OriGene genome-wide validated SYBR primer pairs Browse OriGene validated miRNA SYBR primer pairs Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat TRBV27 Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRBV27 Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRBV27
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Orthologsfor TRBV27 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of chordates.
Orthologs for TRBV27 gene from 2/4 species (see all 4 ) About this table
ENSEMBL Gene Tree for TRBV27 (if available)TreeFam Gene Tree for TRBV27 (if available)
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Paralogsfor TRBV27 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for TRBV27 gene TRBV11-1 2 TRBV3-1 2 TRBV19 2 TRBV9 2 TRBV7-3 2 TRBV6-5 2 TRBV21OR9-2 2 TRBV7-4 2 TRBV6-6 2 TRBV25-1 2 TRBV23OR9-2 2 TRBV5-1 2 TRBV4-1 2 TRBV7-1 2 TRBV6-8 2 TRBV5-7 2 TRBV6-1 2 TRBV10-1 2 TRBV7-7 2 TRBV23-1 2 TRBV5-3 2 TRBV28 2 TRBV6-4 2 TRBV2 2 TRBV6-7 2 TRBV5-5 2 TRBV5-6 2 TRBV7-6 2 TRBV25OR9-2 2 TRBV10-2 2 TRBV5-4 2 TRBV24-1 2 TRBV7-8 2 TRBV6-9 2 TRBV4-2 2
TRBV27 for paralogs About GeneDecksing
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Genomic Variantsfor TRBV27 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section SABiosciences Cancer Mutation PCR Assays
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Disorders
/ Diseasesfor TRBV27 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
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Publicationsfor TRBV27 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for TRBV27 gene integrated from 9 sources : (articles sorted by number of sources associating them with TRBV27) Utopia : connect your pdf to the dynamic world of online information
The complete 685-kilobase DNA sequence of the human beta T cell receptor locus. (PubMed id 8650574) 1 , 3 Rowen L.... Hood L. (1996) Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039) 1 Ota T.... Sugano S. (2004)
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External Searches for TRBV27 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing TRBV27 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing TRBV27 gene
(According to HUGE )
About This Section --
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Specialized Databases showing TRBV27 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for TRBV27 Pharmacogenomics, SNPs, Pathways IMGT entry for TRBV27 The international I mM unoG eneT ics information system® specializing in Immunoglobulins (IG), T cell receptors (TR), Major Histocompatibility Complex (MHC) and related proteins of the immune system (RPI) of human and other vertebrate species.
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About This Section Patent Information for TRBV27 gene: Search GeneIP for patents involving TRBV27 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor TRBV27 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TRBV27 Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TRBV27 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRBV27 Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TRBV27 Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRBV27 Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRBV27
Search Tocris compounds for TRBV27
Search ThermoFisher Antibodies for TRBV27
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TRBV27
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Expression for TRBV27
Function for TRBV27
Genomic Views for TRBV27
Intellectual Property for TRBV27
Orthologs for TRBV27
Paralogs for TRBV27
Pathways / Interactions for TRBV27
Products for TRBV27
Proteins for TRBV27
Publications for TRBV27
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