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Aliases for TRBV25-1 Gene

Aliases for TRBV25-1 Gene

  • T Cell Receptor Beta Variable 25-1 2 3
  • V_segment Translation Product 3
  • TCRBV11S1A1T 3
  • TCRBV25S1 3
  • TRBV251 3
  • TRBC1 4

External Ids for TRBV25-1 Gene

Previous GeneCards Identifiers for TRBV25-1 Gene

  • GC07U990185
  • GC07P141742
  • GC07P141818
  • GC07P141864
  • GC07P142058
  • GC07Pg41749
  • GC07P142381
  • GC07P142382
  • GC07P142394
  • GC07P142437
  • GC07P142483
  • GC07P142640
  • GC07P142710
  • GC07P142772

Summaries for TRBV25-1 Gene

GeneCards Summary for TRBV25-1 Gene

TRBV25-1 (T Cell Receptor Beta Variable 25-1) is a Protein Coding gene. An important paralog of this gene is TRBV2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRBV25-1 Gene

Genomics for TRBV25-1 Gene

Genomic Location for TRBV25-1 Gene

142,670,740 bp from pter
142,793,141 bp from pter
122,402 bases
Plus strand

Genomic View for TRBV25-1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TRBV25-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRBV25-1 Gene

No data available for Regulatory Elements for TRBV25-1 Gene

Proteins for TRBV25-1 Gene

  • Protein details for TRBV25-1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    T-cell receptor beta-1 chain C region
    Protein Accession:
    Secondary Accessions:
    • A0A5B8
    • A6NH51

    Protein attributes for TRBV25-1 Gene

    177 amino acids
    Molecular mass:
    19899 Da
    Quaternary structure:
    No Data Available
    • Sequence=CAA25134.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for TRBV25-1 Gene

neXtProt entry for TRBV25-1 Gene

Proteomics data for TRBV25-1 Gene at MOPED

Post-translational modifications for TRBV25-1 Gene

Other Protein References for TRBV25-1 Gene

ENSEMBL proteins:
Reactome Protein details:

No data available for DME Specific Peptides for TRBV25-1 Gene

Domains for TRBV25-1 Gene

Gene Families for TRBV25-1 Gene

  • TRB :T cell receptors / TRB locus

Protein Domains for TRBV25-1 Gene

Graphical View of Domain Structure for InterPro Entry



  • P01850
  • Contains 1 Ig-like (immunoglobulin-like) domain.
genes like me logo Genes that share domains with TRBV25-1: view

No data available for Suggested Antigen Peptide Sequences for TRBV25-1 Gene

Function for TRBV25-1 Gene

Gene Ontology (GO) - Molecular Function for TRBV25-1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with TRBV25-1: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TRBV25-1 Gene

Localization for TRBV25-1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TRBV25-1 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

Jensen Localization Image for TRBV25-1 Gene COMPARTMENTS Subcellular localization image for TRBV25-1 gene
Compartment Confidence
extracellular 3
cytosol 1
nucleus 1

Gene Ontology (GO) - Cellular Components for TRBV25-1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane --
GO:0016020 membrane --
GO:0016021 integral component of membrane --
genes like me logo Genes that share ontologies with TRBV25-1: view

Pathways for TRBV25-1 Gene

SuperPathways for TRBV25-1 Gene

No Data Available

Interacting Proteins for TRBV25-1 Gene

Selected Interacting proteins: P01850-TRBC1_HUMAN for TRBV25-1 Gene via MINT UniProtKB I2D

Gene Ontology (GO) - Biological Process for TRBV25-1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006955 immune response --
GO:0031295 T cell costimulation --
GO:0050776 regulation of immune response --
GO:0050852 T cell receptor signaling pathway --
genes like me logo Genes that share ontologies with TRBV25-1: view

No data available for Pathways by source for TRBV25-1 Gene

Transcripts for TRBV25-1 Gene

mRNA/cDNA for TRBV25-1 Gene

(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TRBV25-1 Gene

No ASD Table

Relevant External Links for TRBV25-1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TRBV25-1 Gene

mRNA expression in normal human tissues for TRBV25-1 Gene

mRNA differential expression in normal tissues according to GTEx for TRBV25-1 Gene

This gene is overexpressed in Whole Blood (17.9) and Brain - Nucleus accumbens (basal ganglia) (6.9).

Protein differential expression in normal tissues for TRBV25-1 Gene

This gene is overexpressed in Tlymphocyte (51.6), CD4 Tcells (8.8), and Peripheral blood mononuclear cells (7.0).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for TRBV25-1 Gene

genes like me logo Genes that share expressions with TRBV25-1: view

Expression partners for TRBV25-1 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for TRBV25-1 Gene

Orthologs for TRBV25-1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TRBV25-1 Gene

Organism Taxonomy Gene Similarity Type Details
(Canis familiaris)
Mammalia TRBV25-1 36
  • 61 (a)
(Pan troglodytes)
Mammalia TRBV25-1 36
  • 79 (a)
(Gallus gallus)
Aves -- 36
  • 33 (a)
-- 36
  • 38 (a)
-- 36
  • 29 (a)
(Anolis carolinensis)
Reptilia -- 36
  • 20 (a)
-- 36
  • 31 (a)
Species with no ortholog for TRBV25-1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TRBV25-1 Gene

Gene Tree for TRBV25-1 (if available)
Gene Tree for TRBV25-1 (if available)

Paralogs for TRBV25-1 Gene

genes like me logo Genes that share paralogs with TRBV25-1: view

Variants for TRBV25-1 Gene

Relevant External Links for TRBV25-1 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for TRBV25-1 Gene

Disorders for TRBV25-1 Gene

No disorders were found for TRBV25-1 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for TRBV25-1 Gene

Publications for TRBV25-1 Gene

  1. The complete 685-kilobase DNA sequence of the human beta T cell receptor locus. (PMID: 8650574) Rowen L. … Hood L. (Science 1996) 2 3 4
  2. Sequence and evolution of the human T-cell antigen receptor beta- chain genes. (PMID: 3860845) Tunnacliffe A. … Rabbitts T.H. (Proc. Natl. Acad. Sci. U.S.A. 1985) 4
  3. A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains. (PMID: 6336315) Yanagi Y. … Mak T.W. (Nature 1984) 4
  4. A structural basis for immunodominant human T cell receptor recognition. (PMID: 12796775) Stewart-Jones G.B.E. … Jones E.Y. (Nat. Immunol. 2003) 4
  5. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 4

Products for TRBV25-1 Gene

Sources for TRBV25-1 Gene

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