TRBV19 Gene
protein-coding GIFtS : 20
GCID: GC07 P142632
T cell receptor beta variable 19
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Aliasesfor TRBV19 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases T Cell Receptor Beta Variable 19 1 2 TCRBV17S1A1T1 2 TCRBV19S11 2
Export aliases for TRBV19 gene to outside databases Previous GC identifers: GC07U990191 GC07P141691 GC07P141768 GC07P141814 GC07P141671 GC07P142035 GC07P142049 GC07P142066 GC07P142081 GC07P142093 GC07P142110 GC07P142133 GC07P142327 GC07P142329 GC07P142384 GC07P142420 GC07P142471
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Summariesfor TRBV19 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
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Genomic Viewsfor TRBV19 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000007.13 NC_018918.1 NT_007914.15 NT_079596.2 Regulatory elements: Search SABiosciences Regulatory transcription factor binding sites for TRBV19 Other transcription factors Search SABiosciences Chromatin IP Primers for TRBV19 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRBV19
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 7q34 Ensembl cytogenetic band: 7q34 HGNC cytogenetic band: 7q34 TRBV19 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 7 GeneLoc Exon Structure
GeneLoc location for GC07P142632: view genomic region
(about GC identifiers )
Start:
142,326,363 bp from pter
End:
142,327,046 bp from pter
Size:
684 bases
Orientation:
plus strand
1 alternative location : Chr 7+,CRA_TCAG 141,699,293-141,699,768
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Proteinsfor TRBV19 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB: --TRBV19 Protein expression data from MOPED and PaxDb : About this image
ENSEMBL proteins: ENSP00000374916 Human Recombinant Protein Products: Antibody Products for TRBV19: Assay Products for TRBV19:
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Protein
Domains / Familiesfor TRBV19 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
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Functionfor TRBV19 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section
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Pathways & Interactionsfor TRBV19 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TRBV19
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Drugs & Compoundsfor TRBV19 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for TRBV19 Search CenterWatch for drugs/clinical trials and news about TRBV19
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Transcriptsfor TRBV19 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section Unigene Cluster for TRBV19:
T cell receptor beta variable 19 Hs.511720 [show with all ESTs ] Unigene Representative Sequence: BC073930 1 Ensembl transcript including schematic representation, and UCSC links where relevant : ENST00000390393 (uc003vzo.2 ) Additional cDNA sequence: AB305815.1 AB305838.1 AB305839.1 AB305841.1 AB305857.1 AB305918.1 AB305919.1 AB305934.1 AB305938.1 AB305949.1 AB305963.1 AB305970.1 AB305971.1 AB305972.1 AB305976.1 AB305980.1 AB305983.1 AB305984.1 AB306154.1 AB306192.1 AB306212.1 AF009788.1 AF020644.1 AF020646.1 AF020648.1 AF020650.1 AF043180.1 AF200428.1 AJ296350.1 AY239356.1 AY247832.1 AY534310.1 AY751863.1 AY751888.1 AY751910.1 AY751930.1 BC073930.1 HM467901.1 L34719.1 L34733.1 M27388.1 M97725.1 S63251.1 U39120.1 U39129.1 U39130.1 U39138.1 U39143.1 U41098.1 X61629.1 X74851.1 X86109.1 X86113.1 X86118.1 X86119.1 X86120.1 X86122.1 X86123.1 X86127.1 Y10199.1 Y10201.1 Z47376.1 Z77841.1 Z77849.1
12 DOTS entries : DT.121076352 DT.92456573 DT.121076103 DT.95195288 DT.98132111 DT.95124795 DT.95325844 DT.121076615
DT.121076703 DT.91963304 DT.91989657 DT.121076145 24/76 AceView cDNA sequences (see all 76 ):
CR620981 CR598684 CR609731 CR614480 CR626342 CR622128 CR602039 CR610034 BX112874 CR606882 CR591596 CR620061 CR596519 CR608304 CR623833 CR622874 CR623178 CR599262 AY232285 X00437 AY232284 AL559249 AA380633 AK097858 GeneLoc Exon Structure
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Expression for TRBV19 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section TRBV19 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: --
About this image See TRBV19 Protein Expression from SPIRE MOPED and PaxDB SOURCE GeneReport for Unigene cluster: Hs.511720 SABiosciences Custom PCR Arrays for TRBV19 Primer Products: Browse OriGene genome-wide validated SYBR primer pairs Browse OriGene validated miRNA SYBR primer pairs Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat TRBV19 Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRBV19 Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRBV19
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Orthologsfor TRBV19 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of chordates.
Orthologs for TRBV19 gene from 2 species (see representative species ) About this table
ENSEMBL Gene Tree for TRBV19 (if available)TreeFam Gene Tree for TRBV19 (if available)
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Paralogsfor TRBV19 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for TRBV19 gene TRBV11-1 2 TRBV3-1 2 TRBV9 2 TRBV7-3 2 TRBV6-5 2 TRBV21OR9-2 2 TRBV7-4 2 TRBV6-6 2 TRBV25-1 2 TRBV23OR9-2 2 TRBV5-1 2 TRBV4-1 2 TRBV7-1 2 TRBV6-8 2 TRBV5-7 2 TRBV6-1 2 TRBV10-1 2 TRBV7-7 2 TRBV23-1 2 TRBV5-3 2 TRBV28 2 TRBV6-4 2 TRBV2 2 TRBV6-7 2 TRBV27 2 TRBV5-5 2 TRBV5-6 2 TRBV7-6 2 TRBV25OR9-2 2 TRBV10-2 2 TRBV5-4 2 TRBV24-1 2 TRBV7-8 2 TRBV6-9 2 TRBV4-2 2
TRBV19 for paralogs About GeneDecksing
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Genomic Variantsfor TRBV19 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section SABiosciences Cancer Mutation PCR Assays
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Disorders
/ Diseasesfor TRBV19 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
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Publicationsfor TRBV19 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for TRBV19 gene integrated from 9 sources : (articles sorted by number of sources associating them with TRBV19) Utopia : connect your pdf to the dynamic world of online information
The complete 685-kilobase DNA sequence of the human beta T cell receptor locus. (PubMed id 8650574) 1 , 3 Rowen L.... Hood L. (1996) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 Strausberg R.L....Marra M.A. (2002) Allelic variants of human TCR BV17S1 defined by restriction fragment length polymorphism, single strand conformation polymorphism, and amplification refractory mutation system analyses. (PubMed id 8872162) 1 Li Y....Friedman S.M. (1996) Nucleotide sequence analysis of 77.7 kb of the human V beta T-cell receptor gene locus: direct primer-walking using cosmid template DNAs. (PubMed id 8020962) 1 Slightom J.L.... Hood L. (1994)
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External Searches for TRBV19 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing TRBV19 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing TRBV19 gene
(According to HUGE )
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Specialized Databases showing TRBV19 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for TRBV19 Pharmacogenomics, SNPs, Pathways IMGT entry for TRBV19 The international I mM unoG eneT ics information system® specializing in Immunoglobulins (IG), T cell receptors (TR), Major Histocompatibility Complex (MHC) and related proteins of the immune system (RPI) of human and other vertebrate species.
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About This Section Patent Information for TRBV19 gene: Search GeneIP for patents involving TRBV19 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor TRBV19 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TRBV19 Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TRBV19 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRBV19 Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TRBV19 Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRBV19 Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRBV19
Search Tocris compounds for TRBV19
Search ThermoFisher Antibodies for TRBV19
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TRBV19
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Databases for TRBV19
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Domains / Families for TRBV19
Drugs / Compounds for TRBV19
Expression for TRBV19
Function for TRBV19
Genomic Views for TRBV19
Intellectual Property for TRBV19
Orthologs for TRBV19
Paralogs for TRBV19
Pathways / Interactions for TRBV19
Products for TRBV19
Proteins for TRBV19
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