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Aliases for TRBV12-3 Gene

Aliases for TRBV12-3 Gene

  • T Cell Receptor Beta Variable 12-3 2 3
  • TCRBV8S1 3 4
  • V_segment Translation Product 3
  • TCRBV12S3 3
  • TRBV123 3

External Ids for TRBV12-3 Gene

Previous GeneCards Identifiers for TRBV12-3 Gene

  • GC07U990200
  • GC07P141633
  • GC07P141711
  • GC07P141712
  • GC07P141755
  • GC07P141949
  • GC07Pg41640

Summaries for TRBV12-3 Gene

GeneCards Summary for TRBV12-3 Gene

TRBV12-3 (T Cell Receptor Beta Variable 12-3) is a Protein Coding gene. Among its related pathways are Class I MHC mediated antigen processing and presentation and TCR signaling (REACTOME). GO annotations related to this gene include peptide antigen binding and MHC protein binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRBV12-3 Gene

Genomics for TRBV12-3 Gene

Genomic Location for TRBV12-3 Gene

Start:
142,560,423 bp from pter
End:
142,560,931 bp from pter
Size:
509 bases
Orientation:
Plus strand

Genomic View for TRBV12-3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TRBV12-3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRBV12-3 Gene

No data available for Regulatory Elements for TRBV12-3 Gene

Proteins for TRBV12-3 Gene

  • Protein details for TRBV12-3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P01733-TVB1_HUMAN
    Recommended name:
    T-cell receptor beta chain V region YT35
    Protein Accession:
    P01733
    Secondary Accessions:
    • A0A5A7

    Protein attributes for TRBV12-3 Gene

    Size:
    135 amino acids
    Molecular mass:
    15097 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRBV12-3 Gene

Proteomics data for TRBV12-3 Gene at MOPED

Post-translational modifications for TRBV12-3 Gene

No Post-translational modifications

Other Protein References for TRBV12-3 Gene

ENSEMBL proteins:
Reactome Protein details:

No data available for DME Specific Peptides for TRBV12-3 Gene

Domains for TRBV12-3 Gene

Gene Families for TRBV12-3 Gene

HGNC:
  • TRB :T cell receptors / TRB locus

Protein Domains for TRBV12-3 Gene

Suggested Antigen Peptide Sequences for TRBV12-3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRBV12-3: view

No data available for UniProtKB/Swiss-Prot for TRBV12-3 Gene

Function for TRBV12-3 Gene

Gene Ontology (GO) - Molecular Function for TRBV12-3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
GO:0042287 MHC protein binding NAS 6336315
GO:0042605 peptide antigen binding NAS 6336315
genes like me logo Genes that share ontologies with TRBV12-3: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TRBV12-3 Gene

Localization for TRBV12-3 Gene

Gene Ontology (GO) - Cellular Components for TRBV12-3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
genes like me logo Genes that share ontologies with TRBV12-3: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from COMPARTMENTS for TRBV12-3 Gene

Pathways for TRBV12-3 Gene

genes like me logo Genes that share pathways with TRBV12-3: view

Interacting Proteins for TRBV12-3 Gene

Selected Interacting proteins: P01733-TVB1_HUMAN for TRBV12-3 Gene via MINT

Symbol External ID(s) Details
--

Gene Ontology (GO) - Biological Process for TRBV12-3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006955 immune response NAS 6336315
GO:0031295 T cell costimulation TAS --
GO:0050776 regulation of immune response TAS --
GO:0050852 T cell receptor signaling pathway TAS --
genes like me logo Genes that share ontologies with TRBV12-3: view

Transcripts for TRBV12-3 Gene

mRNA/cDNA for TRBV12-3 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for TRBV12-3 Gene

No ASD Table

Relevant External Links for TRBV12-3 Gene

GeneLoc Exon Structure for
TRBV12-3
ECgene alternative splicing isoforms for
TRBV12-3

Expression for TRBV12-3 Gene

Protein differential expression in normal tissues for TRBV12-3 Gene

This gene is overexpressed in CD4 Tcells (69.0).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for TRBV12-3 Gene

Expression partners for TRBV12-3 Gene

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TRBV12-3 Gene

Orthologs for TRBV12-3 Gene

Evolution for TRBV12-3 Gene

ENSEMBL:
Gene Tree for TRBV12-3 (if available)
TreeFam:
Gene Tree for TRBV12-3 (if available)

No data available for Orthologs for TRBV12-3 Gene

Paralogs for TRBV12-3 Gene

genes like me logo Genes that share paralogs with TRBV12-3: view

No data available for Paralogs for TRBV12-3 Gene

Variants for TRBV12-3 Gene

Relevant External Links for TRBV12-3 Gene

HapMap Linkage Disequilibrium report
TRBV12-3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for TRBV12-3 Gene

Disorders for TRBV12-3 Gene

No disorders were found for TRBV12-3 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for TRBV12-3 Gene

Publications for TRBV12-3 Gene

  1. A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains. (PMID: 6336315) Yanagi Y. … Mak T.W. (Nature 1984) 3 4
  2. The complete 685-kilobase DNA sequence of the human beta T cell receptor locus. (PMID: 8650574) Rowen L. … Hood L. (Science 1996) 2 3
  3. Sequence and evolution of the human germline V lambda repertoire. (PMID: 8951372) Williams S.C. … Winter G. (J. Mol. Biol. 1996) 3
  4. The mechanism of phospholipase C-gamma1 regulation. (PMID: 11048639) Kim M.J. … Suh P.G. (Exp. Mol. Med. 2000) 3
  5. Adapters in lymphocyte signaling. (PMID: 11827988) Leo A. … Schraven B. (J. Clin. Invest. 2002) 3

Products for TRBV12-3 Gene

Sources for TRBV12-3 Gene

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