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Aliases for TRBV12-3 Gene

Aliases for TRBV12-3 Gene

  • T Cell Receptor Beta Variable 12-3 2 3 5
  • TCRBV8S1 3 4
  • V_segment Translation Product 3
  • TCRBV12S3 3
  • TRBV123 3

External Ids for TRBV12-3 Gene

Previous GeneCards Identifiers for TRBV12-3 Gene

  • GC07U990200
  • GC07P141633
  • GC07P141711
  • GC07P141712
  • GC07P141755
  • GC07P141949
  • GC07Pg41640
  • GC07P142754
  • GC07P142968

Summaries for TRBV12-3 Gene

GeneCards Summary for TRBV12-3 Gene

TRBV12-3 (T Cell Receptor Beta Variable 12-3) is a Protein Coding gene. Among its related pathways are Immune System and CD28 co-stimulation. GO annotations related to this gene include peptide antigen binding and MHC protein binding. An important paralog of this gene is TRBV2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRBV12-3 Gene

Genomics for TRBV12-3 Gene

Genomic Location for TRBV12-3 Gene

Chromosome:
7
Start:
142,560,423 bp from pter
End:
142,560,931 bp from pter
Size:
509 bases
Orientation:
Plus strand

Genomic View for TRBV12-3 Gene

Genes around TRBV12-3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRBV12-3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRBV12-3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRBV12-3 Gene

No data available for Regulatory Elements for TRBV12-3 Gene

Proteins for TRBV12-3 Gene

  • Protein details for TRBV12-3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P01733-TVB1_HUMAN
    Recommended name:
    T-cell receptor beta chain V region YT35
    Protein Accession:
    P01733
    Secondary Accessions:
    • A0A5A7

    Protein attributes for TRBV12-3 Gene

    Size:
    135 amino acids
    Molecular mass:
    15097 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRBV12-3 Gene

Proteomics data for TRBV12-3 Gene at MOPED

Post-translational modifications for TRBV12-3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for TRBV12-3 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRBV12-3 Gene

Domains & Families for TRBV12-3 Gene

Gene Families for TRBV12-3 Gene

Protein Domains for TRBV12-3 Gene

Suggested Antigen Peptide Sequences for TRBV12-3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRBV12-3: view

No data available for UniProtKB/Swiss-Prot for TRBV12-3 Gene

Function for TRBV12-3 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRBV12-3 Gene

Localization for TRBV12-3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TRBV12-3 Gene

Pathways & Interactions for TRBV12-3 Gene

genes like me logo Genes that share pathways with TRBV12-3: view

Pathways by source for TRBV12-3 Gene

Interacting Proteins for TRBV12-3 Gene

Selected Interacting proteins: P01733-TVB1_HUMAN for TRBV12-3 Gene via MINT

Symbol External ID(s) Details
--

Gene Ontology (GO) - Biological Process for TRBV12-3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006955 immune response NAS 6336315
GO:0031295 T cell costimulation TAS --
genes like me logo Genes that share ontologies with TRBV12-3: view

No data available for SIGNOR curated interactions for TRBV12-3 Gene

Drugs & Compounds for TRBV12-3 Gene

No Compound Related Data Available

Transcripts for TRBV12-3 Gene

mRNA/cDNA for TRBV12-3 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for TRBV12-3 Gene

No ASD Table

Relevant External Links for TRBV12-3 Gene

GeneLoc Exon Structure for
TRBV12-3
ECgene alternative splicing isoforms for
TRBV12-3

Expression for TRBV12-3 Gene

Protein differential expression in normal tissues from HIPED for TRBV12-3 Gene

This gene is overexpressed in CD4 Tcells (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TRBV12-3 Gene



Protein tissue co-expression partners for TRBV12-3 Gene

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TRBV12-3 Gene

Orthologs for TRBV12-3 Gene

Evolution for TRBV12-3 Gene

ENSEMBL:
Gene Tree for TRBV12-3 (if available)
TreeFam:
Gene Tree for TRBV12-3 (if available)

No data available for Orthologs for TRBV12-3 Gene

Paralogs for TRBV12-3 Gene

genes like me logo Genes that share paralogs with TRBV12-3: view

Variants for TRBV12-3 Gene

Relevant External Links for TRBV12-3 Gene

HapMap Linkage Disequilibrium report
TRBV12-3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRBV12-3 Gene

Disorders for TRBV12-3 Gene

No disorders were found for TRBV12-3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for TRBV12-3 Gene

Publications for TRBV12-3 Gene

  1. The complete 685-kilobase DNA sequence of the human beta T cell receptor locus. (PMID: 8650574) Rowen L. … Hood L. (Science 1996) 2 3 67
  2. Global landscape of HIV-human protein complexes. (PMID: 22190034) JAoger S. … Krogan N.J. (Nature 2012) 3
  3. Keeping the (kinase) party going: SLP-76 and ITK dance to the beat. (PMID: 17652306) Qi Q. … August A. (Sci. STKE 2007) 3
  4. An improved method for the synthesis of cellulose membrane-bound peptides with free C termini is useful for PDZ domain binding studies. (PMID: 15123239) Boisguerin P. … Volkmer-Engert R. (Chem. Biol. 2004) 3
  5. Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation. (PMID: 15489916) Palacios E.H. … Weiss A. (Oncogene 2004) 3

Products for TRBV12-3 Gene

Sources for TRBV12-3 Gene

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