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Aliases for TRBV12-3 Gene

Aliases for TRBV12-3 Gene

  • T-Cell Receptor Beta Variable 12-3 2
  • T Cell Receptor Beta Variable 12-3 2 3
  • TCRBV8S1 3 4
  • V_segment Translation Product 3
  • TCRBV12S3 3
  • TRBV123 3

External Ids for TRBV12-3 Gene

Previous GeneCards Identifiers for TRBV12-3 Gene

  • GC07U990200
  • GC07P141633
  • GC07P141711
  • GC07P141712
  • GC07P141755
  • GC07P141949
  • GC07Pg41640
  • GC07P142754
  • GC07P142968
  • GC07P143120
  • GC07P143331
  • GC07P143471
  • GC07P143612

Summaries for TRBV12-3 Gene

GeneCards Summary for TRBV12-3 Gene

TRBV12-3 (T-Cell Receptor Beta Variable 12-3) is a Protein Coding gene. Among its related pathways are TCR signaling (REACTOME) and Translocation of ZAP-70 to Immunological synapse. GO annotations related to this gene include peptide antigen binding and MHC protein binding.

Additional gene information for TRBV12-3 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRBV12-3 Gene

Genomics for TRBV12-3 Gene

Regulatory Elements for TRBV12-3 Gene

Enhancers for TRBV12-3 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH07H142560 0.2 Ensembl 0.7 +0.4 416 0 TRBV12-3 ENSG00000276953
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TRBV12-3 on UCSC Golden Path with GeneCards custom track

Genomic Location for TRBV12-3 Gene

Chromosome:
7
Start:
142,560,485 bp from pter
End:
142,560,931 bp from pter
Size:
447 bases
Orientation:
Plus strand

Genomic View for TRBV12-3 Gene

Genes around TRBV12-3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRBV12-3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRBV12-3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRBV12-3 Gene

Proteins for TRBV12-3 Gene

  • Protein details for TRBV12-3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P01733-TVB1_HUMAN
    Recommended name:
    T-cell receptor beta chain V region YT35
    Protein Accession:
    P01733
    Secondary Accessions:
    • A0A5A7

    Protein attributes for TRBV12-3 Gene

    Size:
    135 amino acids
    Molecular mass:
    15097 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRBV12-3 Gene

Post-translational modifications for TRBV12-3 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for TRBV12-3 Gene

Domains & Families for TRBV12-3 Gene

Gene Families for TRBV12-3 Gene

Protein Domains for TRBV12-3 Gene

Suggested Antigen Peptide Sequences for TRBV12-3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRBV12-3: view

No data available for UniProtKB/Swiss-Prot for TRBV12-3 Gene

Function for TRBV12-3 Gene

Gene Ontology (GO) - Molecular Function for TRBV12-3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0042287 MHC protein binding NAS 6336315
GO:0042605 peptide antigen binding NAS 6336315
genes like me logo Genes that share ontologies with TRBV12-3: view

Animal Model Products

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for TRBV12-3
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRBV12-3 Gene

Localization for TRBV12-3 Gene

Gene Ontology (GO) - Cellular Components for TRBV12-3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
genes like me logo Genes that share ontologies with TRBV12-3: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for TRBV12-3 Gene

Pathways & Interactions for TRBV12-3 Gene

genes like me logo Genes that share pathways with TRBV12-3: view

Interacting Proteins for TRBV12-3 Gene

Gene Ontology (GO) - Biological Process for TRBV12-3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006955 immune response NAS 6336315
GO:0031295 T cell costimulation TAS --
GO:0050776 regulation of immune response TAS --
GO:0050852 T cell receptor signaling pathway TAS --
genes like me logo Genes that share ontologies with TRBV12-3: view

No data available for SIGNOR curated interactions for TRBV12-3 Gene

Drugs & Compounds for TRBV12-3 Gene

No Compound Related Data Available

Transcripts for TRBV12-3 Gene

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for TRBV12-3
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for TRBV12-3 Gene

No ASD Table

Relevant External Links for TRBV12-3 Gene

GeneLoc Exon Structure for
TRBV12-3
ECgene alternative splicing isoforms for
TRBV12-3

Expression for TRBV12-3 Gene

Protein differential expression in normal tissues from HIPED for TRBV12-3 Gene

This gene is overexpressed in CD4 Tcells (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TRBV12-3 Gene



Protein tissue co-expression partners for TRBV12-3 Gene

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRBV12-3 Gene

Orthologs for TRBV12-3 Gene

No data available for Orthologs and Evolution for TRBV12-3 Gene

Paralogs for TRBV12-3 Gene

genes like me logo Genes that share paralogs with TRBV12-3: view

No data available for Paralogs for TRBV12-3 Gene

Variants for TRBV12-3 Gene

Relevant External Links for TRBV12-3 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRBV12-3

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRBV12-3 Gene

Disorders for TRBV12-3 Gene

No disorders were found for TRBV12-3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for TRBV12-3 Gene

Publications for TRBV12-3 Gene

  1. The complete 685-kilobase DNA sequence of the human beta T cell receptor locus. (PMID: 8650574) Rowen L … Hood L (Science (New York, N.Y.) 1996) 2 3 60
  2. A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains. (PMID: 6336315) Yanagi Y … Mak TW (Nature 1984) 3 4 60
  3. Global landscape of HIV-human protein complexes. (PMID: 22190034) Jäger S … Krogan NJ (Nature 2011) 3 60
  4. Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins. (PMID: 19349973) Wollscheid B … Watts JD (Nature biotechnology 2009) 4 60
  5. Keeping the (kinase) party going: SLP-76 and ITK dance to the beat. (PMID: 17652306) Qi Q … August A (Science's STKE : signal transduction knowledge environment 2007) 3 60

Products for TRBV12-3 Gene

Sources for TRBV12-3 Gene

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