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Aliases for TRBC2 Gene

Aliases for TRBC2 Gene

  • T Cell Receptor Beta Constant 2 2 3
  • TCRBC2 3 4
  • V_segment Translation Product 3

External Ids for TRBC2 Gene

Summaries for TRBC2 Gene

GeneCards Summary for TRBC2 Gene

TRBC2 (T Cell Receptor Beta Constant 2) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRBC2 Gene

Genomics for TRBC2 Gene

Genomic Location for TRBC2 Gene

Start:
142,670,777 bp from pter
End:
142,802,748 bp from pter
Size:
131,972 bases
Orientation:
Plus strand

Genomic View for TRBC2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for TRBC2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRBC2 Gene

No data available for Regulatory Elements for TRBC2 Gene

Proteins for TRBC2 Gene

  • Protein details for TRBC2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A0A5B9-TRBC2_HUMAN
    Recommended name:
    T-cell receptor beta-2 chain C region
    Protein Accession:
    A0A5B9
    Secondary Accessions:

    Protein attributes for TRBC2 Gene

    Size:
    178 amino acids
    Molecular mass:
    19969 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for TRBC2 Gene

neXtProt entry for TRBC2 Gene

Proteomics data for TRBC2 Gene at MOPED

Post-translational modifications for TRBC2 Gene

Other Protein References for TRBC2 Gene

No data available for DME Specific Peptides for TRBC2 Gene

Domains for TRBC2 Gene

Gene Families for TRBC2 Gene

HGNC:
  • TRB :T cell receptors / TRB locus

Protein Domains for TRBC2 Gene

Suggested Antigen Peptide Sequences for TRBC2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A0A5B9

UniProtKB/Swiss-Prot:

TRBC2_HUMAN
Domain:
  • Contains 1 Ig-like (immunoglobulin-like) domain.:
    • A0A5B9
genes like me logo Genes that share domains with TRBC2: view

Function for TRBC2 Gene

Gene Ontology (GO) - Molecular Function for TRBC2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with TRBC2: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for TRBC2 Gene

Localization for TRBC2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TRBC2 Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for TRBC2 Gene COMPARTMENTS Subcellular localization image for TRBC2 gene
Compartment Confidence
plasma membrane 4
cytosol 1
extracellular 1
mitochondrion 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for TRBC2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TRBC2: view

Pathways for TRBC2 Gene

SuperPathways for TRBC2 Gene

No Data Available

Interacting Proteins for TRBC2 Gene

Gene Ontology (GO) - Biological Process for TRBC2 Gene

None

No data available for Pathways by source for TRBC2 Gene

Transcripts for TRBC2 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for TRBC2 Gene

No ASD Table

Relevant External Links for TRBC2 Gene

GeneLoc Exon Structure for
TRBC2
ECgene alternative splicing isoforms for
TRBC2

Expression for TRBC2 Gene

mRNA expression in normal human tissues for TRBC2 Gene

mRNA differential expression in normal tissues according to GTEx for TRBC2 Gene

This gene is overexpressed in Whole Blood (23.9), Spleen (7.1), and Small Intestine - Terminal Ileum (4.6).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for TRBC2 Gene

genes like me logo Genes that share expressions with TRBC2: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for TRBC2 Gene

Orthologs for TRBC2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TRBC2 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia -- 36
  • 74 (a)
OneToMany
-- 36
  • 46 (a)
OneToMany
-- 36
  • 73 (a)
OneToMany
dog
(Canis familiaris)
Mammalia TRBC2 36
  • 45 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Trbc1 36
  • 80 (a)
OneToMany
Trbc2 36
  • 80 (a)
OneToMany
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 60 (a)
OneToMany
-- 36
  • 58 (a)
OneToMany
-- 36
  • 63 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia TRBC2 36
  • 59 (a)
OneToOne
chicken
(Gallus gallus)
Aves TRBC2 36
  • 34 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia TRBC2 36
  • 33 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii TRBC2 36
  • 27 (a)
OneToOne
Species with no ortholog for TRBC2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for TRBC2 Gene

ENSEMBL:
Gene Tree for TRBC2 (if available)
TreeFam:
Gene Tree for TRBC2 (if available)

Paralogs for TRBC2 Gene

Selected SIMAP similar genes for TRBC2 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with TRBC2: view

No data available for Paralogs for TRBC2 Gene

Variants for TRBC2 Gene

Relevant External Links for TRBC2 Gene

HapMap Linkage Disequilibrium report
TRBC2

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Structural Variations from Database of Genomic Variants (DGV) for TRBC2 Gene

Disorders for TRBC2 Gene

No disorders were found for TRBC2 Gene.

No data available for UniProtKB/Swiss-Prot for TRBC2 Gene

Publications for TRBC2 Gene

  1. Sequence and evolution of the human T-cell antigen receptor beta- chain genes. (PMID: 3860845) Tunnacliffe A. … Rabbitts T.H. (Proc. Natl. Acad. Sci. U.S.A. 1985) 2 3 4
  2. The complete 685-kilobase DNA sequence of the human beta T cell receptor locus. (PMID: 8650574) Rowen L. … Hood L. (Science 1996) 3 4
  3. Sequence and evolution of the human germline V lambda repertoire. (PMID: 8951372) Williams S.C. … Winter G. (J. Mol. Biol. 1996) 2 3

Products for TRBC2 Gene

Sources for TRBC2 Gene

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