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Aliases for TRBC1 Gene

Aliases for TRBC1 Gene

  • T Cell Receptor Beta Constant 1 2 3
  • V_segment Translation Product 3
  • BV05S1J2.2 3
  • TCRBC1 3
  • TCRB 3

External Ids for TRBC1 Gene

Previous GeneCards Identifiers for TRBC1 Gene

  • GC07U990262
  • GC07P141883
  • GC07P141962
  • GC07P141978
  • GC07P142007
  • GC07P141757
  • GC07P141672
  • GC07P142213
  • GC07P142227
  • GC07P142239
  • GC07P142251
  • GC07P142264
  • GC07P142278
  • GC07P142289
  • GC07Pg41892
  • GC07Pg41908
  • GC07P142297
  • GC07Pg41923
  • GC07Pg41929
  • GC07Pg41935
  • GC07Pg41941
  • GC07P9T0995
  • GC07P9T0100
  • GC07P142868

Summaries for TRBC1 Gene

GeneCards Summary for TRBC1 Gene

TRBC1 (T Cell Receptor Beta Constant 1) is a Protein Coding gene. Among its related pathways are Immune System and TCR signaling (REACTOME).

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRBC1 Gene

Genomics for TRBC1 Gene

Genomic Location for TRBC1 Gene

Chromosome:
7
Start:
142,791,694 bp from pter
End:
142,793,141 bp from pter
Size:
1,448 bases
Orientation:
Plus strand

Genomic View for TRBC1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for TRBC1 Gene

No data available for Regulatory Elements for TRBC1 Gene

Proteins for TRBC1 Gene

  • Protein details for TRBC1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P01850-TRBC1_HUMAN
    Recommended name:
    T-cell receptor beta-1 chain C region
    Protein Accession:
    P01850
    Secondary Accessions:
    • A0A5B8
    • A6NH51

    Protein attributes for TRBC1 Gene

    Size:
    177 amino acids
    Molecular mass:
    19899 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAA25134.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305};

    Three dimensional structures from OCA and Proteopedia for TRBC1 Gene

neXtProt entry for TRBC1 Gene

Proteomics data for TRBC1 Gene at MOPED

Post-translational modifications for TRBC1 Gene

  • Glycosylation at Asn 70
  • Modification sites at PhosphoSitePlus

No data available for DME Specific Peptides for TRBC1 Gene

Domains & Families for TRBC1 Gene

Gene Families for TRBC1 Gene

Protein Domains for TRBC1 Gene

Suggested Antigen Peptide Sequences for TRBC1 Gene

Graphical View of Domain Structure for InterPro Entry

P01850

UniProtKB/Swiss-Prot:

TRBC1_HUMAN :
  • Contains 1 Ig-like (immunoglobulin-like) domain.
Domain:
  • Contains 1 Ig-like (immunoglobulin-like) domain.
genes like me logo Genes that share domains with TRBC1: view

Function for TRBC1 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRBC1 Gene

Localization for TRBC1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for TRBC1 Gene

Membrane; Single-pass membrane protein.

Gene Ontology (GO) - Cellular Components for TRBC1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005886 plasma membrane TAS --
GO:0016020 membrane NAS 6336315
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with TRBC1: view

No data available for Subcellular locations from COMPARTMENTS for TRBC1 Gene

Pathways & Interactions for TRBC1 Gene

genes like me logo Genes that share pathways with TRBC1: view

Interacting Proteins for TRBC1 Gene

Selected Interacting proteins: P01850-TRBC1_HUMAN for TRBC1 Gene via I2D UniProtKB MINT

Gene Ontology (GO) - Biological Process for TRBC1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006955 immune response NAS 6336315
GO:0031295 T cell costimulation TAS --
GO:0050776 regulation of immune response TAS --
GO:0050852 T cell receptor signaling pathway TAS --
genes like me logo Genes that share ontologies with TRBC1: view

No data available for SIGNOR curated interactions for TRBC1 Gene

Drugs & Compounds for TRBC1 Gene

(1) Drugs for TRBC1 Gene - From: DrugBank

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
3-Indolebutyric acid Experimental Pharma Target 0
genes like me logo Genes that share compounds with TRBC1: view

Expression for TRBC1 Gene

mRNA expression in normal human tissues for TRBC1 Gene

Protein differential expression in normal tissues from HIPED for TRBC1 Gene

This gene is overexpressed in Tlymphocyte (51.6), CD4 Tcells (8.8), and Peripheral blood mononuclear cells (7.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for TRBC1 Gene



genes like me logo Genes that share expression patterns with TRBC1: view

Protein tissue co-expression partners for TRBC1 Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for TRBC1 Gene

Orthologs for TRBC1 Gene

No data available for Orthologs and Evolution for TRBC1 Gene

Paralogs for TRBC1 Gene

(9) SIMAP similar genes for TRBC1 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with TRBC1: view

No data available for Paralogs for TRBC1 Gene

Variants for TRBC1 Gene

Relevant External Links for TRBC1 Gene

HapMap Linkage Disequilibrium report
TRBC1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRBC1 Gene

Disorders for TRBC1 Gene

Relevant External Links for TRBC1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
TRBC1
genes like me logo Genes that share disorders with TRBC1: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for TRBC1 Gene

Publications for TRBC1 Gene

  1. Protein biomarkers in the plasma of workers occupationally exposed to polycyclic aromatic hydrocarbons. (PMID: 15468311) Kap-Soon N. … Chan-Wha K. (Proteomics 2004) 23 67
  2. Sequence and evolution of the human T-cell antigen receptor beta- chain genes. (PMID: 3860845) Tunnacliffe A. … Rabbitts T.H. (Proc. Natl. Acad. Sci. U.S.A. 1985) 2 67
  3. Global landscape of HIV-human protein complexes. (PMID: 22190034) JAoger S. … Krogan N.J. (Nature 2012) 67
  4. The shaping of T cell receptor recognition by self-tolerance. (PMID: 19167249) Gras S. … Rossjohn J. (Immunity 2009) 67
  5. Keeping the (kinase) party going: SLP-76 and ITK dance to the beat. (PMID: 17652306) Qi Q. … August A. (Sci. STKE 2007) 67

Products for TRBC1 Gene

Sources for TRBC1 Gene

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