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Aliases for TRAV9-1 Gene

Aliases for TRAV9-1 Gene

  • T-Cell Receptor Alpha Variable 9-1 2 5
  • T Cell Receptor Alpha Variable 9-1 2 3
  • TCRAV9S1 3
  • TRAV91 3

External Ids for TRAV9-1 Gene

Previous GeneCards Identifiers for TRAV9-1 Gene

  • GC14U990315
  • GC14P020269
  • GC14P021349
  • GC14P022280
  • GC14P002397

Summaries for TRAV9-1 Gene

Entrez Gene Summary for TRAV9-1 Gene

  • T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016]

GeneCards Summary for TRAV9-1 Gene

TRAV9-1 (T-Cell Receptor Alpha Variable 9-1) is a Protein Coding gene. An important paralog of this gene is TRAV9-2.

Additional gene information for TRAV9-1 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRAV9-1 Gene

Genomics for TRAV9-1 Gene

Regulatory Elements for TRAV9-1 Gene

Enhancers for TRAV9-1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14H021825 0.4 ENCODE 0.4 +13.8 13830 0 CTCF ZNF580 TRAV10 TRAV9-1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TRAV9-1 on UCSC Golden Path with GeneCards custom track

Genomic Location for TRAV9-1 Gene

Chromosome:
14
Start:
21,811,502 bp from pter
End:
21,811,977 bp from pter
Size:
476 bases
Orientation:
Plus strand

Genomic View for TRAV9-1 Gene

Genes around TRAV9-1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRAV9-1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRAV9-1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRAV9-1 Gene

Proteins for TRAV9-1 Gene

  • Protein details for TRAV9-1 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    A0A075B6T8
    Recommended name:
    T-cell receptor alpha variable 9-1
    Protein Accession:
    A0A075B6T8

    Protein attributes for TRAV9-1 Gene

    Size:
    112 amino acids
    Molecular mass:
    12354 Da
    Quaternary structure:
    No Data Available

neXtProt entry for TRAV9-1 Gene

Post-translational modifications for TRAV9-1 Gene

No Post-translational modifications

Other Protein References for TRAV9-1 Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for TRAV9-1 Gene

Domains & Families for TRAV9-1 Gene

Gene Families for TRAV9-1 Gene

Protein Domains for TRAV9-1 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRAV9-1: view

No data available for Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TRAV9-1 Gene

Function for TRAV9-1 Gene

Animal Model Products

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for TRAV9-1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRAV9-1 Gene

Localization for TRAV9-1 Gene

Gene Ontology (GO) - Cellular Components for TRAV9-1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IBA --
genes like me logo Genes that share ontologies with TRAV9-1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for TRAV9-1 Gene

Pathways & Interactions for TRAV9-1 Gene

SuperPathways for TRAV9-1 Gene

No Data Available

Interacting Proteins for TRAV9-1 Gene

Gene Ontology (GO) - Biological Process for TRAV9-1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006955 immune response IBA --
genes like me logo Genes that share ontologies with TRAV9-1: view

No data available for Pathways by source and SIGNOR curated interactions for TRAV9-1 Gene

Drugs & Compounds for TRAV9-1 Gene

No Compound Related Data Available

Transcripts for TRAV9-1 Gene

mRNA/cDNA for TRAV9-1 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Clone Products

  • Applied Biological Materials Clones for TRAV9-1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for TRAV9-1 Gene

No ASD Table

Relevant External Links for TRAV9-1 Gene

GeneLoc Exon Structure for
TRAV9-1
ECgene alternative splicing isoforms for
TRAV9-1

Expression for TRAV9-1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TRAV9-1 Gene

genes like me logo Genes that share expression patterns with TRAV9-1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRAV9-1 Gene

Orthologs for TRAV9-1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for TRAV9-1 Gene

Organism Taxonomy Gene Similarity Type Details
mouse
(Mus musculus)
Mammalia Trav6-5 34
  • 73 (a)
OneToMany
Trav6d-5 34
  • 71 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 50 (a)
ManyToMany
-- 34
  • 44 (a)
ManyToMany
-- 34
  • 44 (a)
ManyToMany
-- 34
  • 43 (a)
ManyToMany
-- 34
  • 42 (a)
ManyToMany
-- 34
  • 38 (a)
ManyToMany
-- 34
  • 36 (a)
ManyToMany
-- 34
  • 32 (a)
ManyToMany
-- 34
  • 32 (a)
ManyToMany
-- 34
  • 30 (a)
ManyToMany
oppossum
(Monodelphis domestica)
Mammalia -- 34
  • 48 (a)
ManyToMany
-- 34
  • 47 (a)
ManyToMany
-- 34
  • 44 (a)
ManyToMany
cow
(Bos Taurus)
Mammalia -- 34
  • 35 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia -- 34
  • 37 (a)
ManyToMany
-- 34
  • 37 (a)
ManyToMany
-- 34
  • 36 (a)
ManyToMany
-- 34
  • 29 (a)
ManyToMany
Species where no ortholog for TRAV9-1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for TRAV9-1 Gene

ENSEMBL:
Gene Tree for TRAV9-1 (if available)
TreeFam:
Gene Tree for TRAV9-1 (if available)

Paralogs for TRAV9-1 Gene

genes like me logo Genes that share paralogs with TRAV9-1: view

Variants for TRAV9-1 Gene

Relevant External Links for TRAV9-1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRAV9-1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRAV9-1 Gene

Disorders for TRAV9-1 Gene

No disorders were found for TRAV9-1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for TRAV9-1 Gene

Publications for TRAV9-1 Gene

  1. The human T-cell receptor TCRAC/TCRDC (C alpha/C delta) region: organization, sequence, and evolution of 97.6 kb of DNA. (PMID: 8188290) Koop BF … Hood L (Genomics 1994) 2 3 60

Products for TRAV9-1 Gene

Sources for TRAV9-1 Gene

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