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Aliases for TRAV37 Gene

Aliases for TRAV37 Gene

  • T Cell Receptor Alpha Variable 37 (Pseudogene) 2 3 5
  • T Cell Receptor Alpha Variable 37 Pseudogene 2
  • T Cell Receptor Alpha Variable 37 2
  • TCRAV37S1 3

External Ids for TRAV37 Gene

Previous GeneCards Identifiers for TRAV37 Gene

  • GC14U990282
  • GC14P020723
  • GC14P021803
  • GC14P022733
  • GC14P002851
  • GC14P022267

Summaries for TRAV37 Gene

Entrez Gene Summary for TRAV37 Gene

  • T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016]

GeneCards Summary for TRAV37 Gene

TRAV37 (T Cell Receptor Alpha Variable 37 (Pseudogene)) is a Pseudogene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRAV37 Gene

Genomics for TRAV37 Gene

Regulatory Elements for TRAV37 Gene

Enhancers for TRAV37 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14F022504 1.7 FANTOM5 Ensembl ENCODE 16.2 +272.4 272439 66.7 MLX CREB3L1 ZFP64 FEZF1 DMAP1 YBX1 YY1 SLC30A9 ZNF143 ZNF548 MMP14 ABHD4 OXA1L LOC105370399 EFS HOMEZ C14orf119 DAD1 ENSG00000258457 TRAV37
GH14F022976 1.4 FANTOM5 ENCODE 16.2 +714.2 714157 7.6 CREB3L1 MLX ZFP64 YBX1 FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF548 PRMT5 HAUS4 LOC102724814 PABPN1 MMP14 LOC105370399 RN7SKP205 LOC105370409 TRAV37 LINC00596
GH14F022265 0.8 Ensembl ENCODE 0.8 +0.1 52 1.2 CTCF ESRRA HLF RAD21 ZFP69B GATA3 ZNF692 FOSL2 FOS TRAV38-1 TRAV37
GH14F022268 1 Ensembl ENCODE 0.8 +3.3 3252 0.4 PKNOX1 FEZF1 GATA3 ZNF366 PATZ1 EED FOSL2 FOS KLF8 JUNB TRAV37 TRAV38-1
GH14F022252 0.9 Ensembl ENCODE 0.4 -12.8 -12804 0.8 HLF OR6E1P TRAV37 TRAV36DV7
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around TRAV37 on UCSC Golden Path with GeneCards custom track

Genomic Location for TRAV37 Gene

Chromosome:
14
Start:
22,265,749 bp from pter
End:
22,267,173 bp from pter
Size:
1,425 bases
Orientation:
Plus strand

Genomic View for TRAV37 Gene

Genes around TRAV37 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRAV37 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRAV37 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRAV37 Gene

Proteins for TRAV37 Gene

Post-translational modifications for TRAV37 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TRAV37 Gene

Domains & Families for TRAV37 Gene

Gene Families for TRAV37 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRAV37: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TRAV37 Gene

Function for TRAV37 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRAV37 Gene

Localization for TRAV37 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TRAV37 Gene

Pathways & Interactions for TRAV37 Gene

SuperPathways for TRAV37 Gene

No Data Available

Interacting Proteins for TRAV37 Gene

Gene Ontology (GO) - Biological Process for TRAV37 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TRAV37 Gene

Transcripts for TRAV37 Gene

mRNA/cDNA for TRAV37 Gene

(1) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TRAV37 Gene

No ASD Table

Relevant External Links for TRAV37 Gene

GeneLoc Exon Structure for
TRAV37
ECgene alternative splicing isoforms for
TRAV37

Expression for TRAV37 Gene

mRNA expression in normal human tissues for TRAV37 Gene

NURSA nuclear receptor signaling pathways regulating expression of TRAV37 Gene:

TRAV37
genes like me logo Genes that share expression patterns with TRAV37: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for TRAV37 Gene

Orthologs for TRAV37 Gene

Evolution for TRAV37 Gene

ENSEMBL:
Gene Tree for TRAV37 (if available)
TreeFam:
Gene Tree for TRAV37 (if available)

No data available for Orthologs for TRAV37 Gene

Paralogs for TRAV37 Gene

No data available for Paralogs for TRAV37 Gene

Variants for TRAV37 Gene

Relevant External Links for TRAV37 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRAV37

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRAV37 Gene

Disorders for TRAV37 Gene

No disorders were found for TRAV37 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for TRAV37 Gene

Publications for TRAV37 Gene

  1. The human T-cell receptor TCRAC/TCRDC (C alpha/C delta) region: organization, sequence, and evolution of 97.6 kb of DNA. (PMID: 8188290) Koop B.F. … Hood L. (Genomics 1994) 2 3 64

Products for TRAV37 Gene

Sources for TRAV37 Gene

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