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Aliases for TRAV31 Gene

Aliases for TRAV31 Gene

  • T-Cell Receptor Alpha Variable 31 (Pseudogene) 2 5
  • T Cell Receptor Alpha Variable 31 (Pseudogene) 2 3
  • T Cell Receptor Alpha Variable 31 Pseudogene 2
  • T Cell Receptor Alpha Variable 31 2
  • TCRAV31S1 3

External Ids for TRAV31 Gene

Previous GeneCards Identifiers for TRAV31 Gene

  • GC14U990288
  • GC14P020635
  • GC14P021715
  • GC14P022645

Summaries for TRAV31 Gene

Entrez Gene Summary for TRAV31 Gene

  • T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016]

GeneCards Summary for TRAV31 Gene

TRAV31 (T-Cell Receptor Alpha Variable 31 (Pseudogene)) is a Pseudogene.

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRAV31 Gene

Genomics for TRAV31 Gene

Regulatory Elements for TRAV31 Gene

Enhancers for TRAV31 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14G022173 1.1 FANTOM5 ENCODE 0.7 -2.2 -2243 3.5 HNRNPUL1 PKNOX1 ATF1 ZSCAN4 ARID4B SIN3A THRB ZNF48 RAD21 ZNF366 TRAV26-2 TRAV31 TRAV30
GH14G022178 0.6 ENCODE 0.7 +1.2 1246 0.2 BHLHE40 CEBPG ZEB1 FOSL1 ZNF335 JUND ZNF629 ZBTB17 SP7 TRAV31 TRAV32
GH14G022177 0.4 ENCODE 0.7 +0.7 746 0.2 GATA2 ATF2 TRAV31 TRAV32
GH14G022184 0.4 ENCODE 0.4 +7.6 7567 0.2 GATA2 FOS TRAV32 TRAV31
GH14G022176 0.2 ENCODE 0.7 -0.3 -294 0.0 TRAV31 TRAV30
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around TRAV31 on UCSC Golden Path with GeneCards custom track

Genomic Location for TRAV31 Gene

Chromosome:
14
Start:
22,177,273 bp from pter
End:
22,177,864 bp from pter
Size:
592 bases
Orientation:
Plus strand

Genomic View for TRAV31 Gene

Genes around TRAV31 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRAV31 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRAV31 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRAV31 Gene

Proteins for TRAV31 Gene

Post-translational modifications for TRAV31 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TRAV31 Gene

Domains & Families for TRAV31 Gene

Gene Families for TRAV31 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRAV31: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TRAV31 Gene

Function for TRAV31 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRAV31 Gene

Localization for TRAV31 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TRAV31 Gene

Pathways & Interactions for TRAV31 Gene

SuperPathways for TRAV31 Gene

No Data Available

Interacting Proteins for TRAV31 Gene

Gene Ontology (GO) - Biological Process for TRAV31 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for TRAV31 Gene

Drugs & Compounds for TRAV31 Gene

No Compound Related Data Available

Transcripts for TRAV31 Gene

mRNA/cDNA for TRAV31 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TRAV31 Gene

No ASD Table

Relevant External Links for TRAV31 Gene

GeneLoc Exon Structure for
TRAV31
ECgene alternative splicing isoforms for
TRAV31

Expression for TRAV31 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for TRAV31 Gene

NURSA nuclear receptor signaling pathways regulating expression of TRAV31 Gene:

TRAV31
genes like me logo Genes that share expression patterns with TRAV31: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for TRAV31 Gene

Orthologs for TRAV31 Gene

Evolution for TRAV31 Gene

ENSEMBL:
Gene Tree for TRAV31 (if available)
TreeFam:
Gene Tree for TRAV31 (if available)

No data available for Orthologs for TRAV31 Gene

Paralogs for TRAV31 Gene

No data available for Paralogs for TRAV31 Gene

Variants for TRAV31 Gene

Relevant External Links for TRAV31 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
TRAV31

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRAV31 Gene

Disorders for TRAV31 Gene

No disorders were found for TRAV31 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for TRAV31 Gene

Publications for TRAV31 Gene

  1. The human T-cell receptor TCRAC/TCRDC (C alpha/C delta) region: organization, sequence, and evolution of 97.6 kb of DNA. (PMID: 8188290) Koop B.F. … Hood L. (Genomics 1994) 2 3 64

Products for TRAV31 Gene

Sources for TRAV31 Gene

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