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Aliases for TRAV28 Gene

Aliases for TRAV28 Gene

  • T Cell Receptor Alpha Variable 28 (Pseudogene) 2 3 5
  • T Cell Receptor Alpha Variable 28 Pseudogene 2
  • T Cell Receptor Alpha Variable 28 2
  • TCRAV28S1 3

External Ids for TRAV28 Gene

Previous GeneCards Identifiers for TRAV28 Gene

  • GC14U990291
  • GC14P020613
  • GC14P021692
  • GC14P022623
  • GC14P002740

Summaries for TRAV28 Gene

Entrez Gene Summary for TRAV28 Gene

  • T cell receptors recognize foreign antigens which have been processed as small peptides and bound to major histocompatibility complex (MHC) molecules at the surface of antigen presenting cells (APC). Each T cell receptor is a dimer consisting of one alpha and one beta chain or one delta and one gamma chain. In a single cell, the T cell receptor loci are rearranged and expressed in the order delta, gamma, beta, and alpha. If both delta and gamma rearrangements produce functional chains, the cell expresses delta and gamma. If not, the cell proceeds to rearrange the beta and alpha loci. This region represents the germline organization of the T cell receptor alpha and delta loci. Both the alpha and delta loci include V (variable), J (joining), and C (constant) segments and the delta locus also includes diversity (D) segments. The delta locus is situated within the alpha locus, between the alpha V and J segments. During T cell development, the delta chain is synthesized by a recombination event at the DNA level joining a D segment with a J segment; a V segment is then joined to the D-J gene. The alpha chain is synthesized by recombination joining a single V segment with a J segment. For both chains, the C segment is later joined by splicing at the RNA level. Recombination of many different V segments with several J segments provides a wide range of antigen recognition. Additional diversity is attained by junctional diversity, resulting from the random additional of nucleotides by terminal deoxynucleotidyltransferase. Five variable segments can be used in either alpha or delta chains and are described by TRAV/DV symbols. Several V and J segments of the alpha locus are known to be incapable of encoding a protein and are considered pseudogenes. [provided by RefSeq, Aug 2016]

GeneCards Summary for TRAV28 Gene

TRAV28 (T Cell Receptor Alpha Variable 28 (Pseudogene)) is a Pseudogene.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for TRAV28 Gene

Genomics for TRAV28 Gene

Regulatory Elements for TRAV28 Gene

Enhancers for TRAV28 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH14F022158 0.9 Ensembl ENCODE 0.8 +5.0 4978 2.8 SCRT1 KLF1 SCRT2 ZBTB40 GABPA NR2C2 TRAV26-2 TRAV28 TRAV29DV5
GH14F022150 0.5 ENCODE 0.8 -3.5 -3462 1.5 SETDB1 TRAV26-2 TRAV27 TRAV28
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around TRAV28 on UCSC Golden Path with GeneCards custom track

Genomic Location for TRAV28 Gene

22,155,079 bp from pter
22,155,638 bp from pter
560 bases
Plus strand

Genomic View for TRAV28 Gene

Genes around TRAV28 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
TRAV28 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for TRAV28 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for TRAV28 Gene

Proteins for TRAV28 Gene

Post-translational modifications for TRAV28 Gene

No Post-translational modifications

No data available for DME Specific Peptides for TRAV28 Gene

Domains & Families for TRAV28 Gene

Gene Families for TRAV28 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with TRAV28: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for TRAV28 Gene

Function for TRAV28 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for TRAV28 Gene

Localization for TRAV28 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for TRAV28 Gene

Pathways & Interactions for TRAV28 Gene

SuperPathways for TRAV28 Gene

No Data Available

Interacting Proteins for TRAV28 Gene

Gene Ontology (GO) - Biological Process for TRAV28 Gene


No data available for Pathways by source and SIGNOR curated interactions for TRAV28 Gene

Transcripts for TRAV28 Gene

mRNA/cDNA for TRAV28 Gene

(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for TRAV28 Gene

No ASD Table

Relevant External Links for TRAV28 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for TRAV28 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for TRAV28 Gene

NURSA nuclear receptor signaling pathways regulating expression of TRAV28 Gene:

genes like me logo Genes that share expression patterns with TRAV28: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for TRAV28 Gene

Orthologs for TRAV28 Gene

Evolution for TRAV28 Gene

Gene Tree for TRAV28 (if available)
Gene Tree for TRAV28 (if available)

No data available for Orthologs for TRAV28 Gene

Paralogs for TRAV28 Gene

No data available for Paralogs for TRAV28 Gene

Variants for TRAV28 Gene

Relevant External Links for TRAV28 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for TRAV28 Gene

Disorders for TRAV28 Gene

No disorders were found for TRAV28 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for TRAV28 Gene

Publications for TRAV28 Gene

  1. The human T-cell receptor TCRAC/TCRDC (C alpha/C delta) region: organization, sequence, and evolution of 97.6 kb of DNA. (PMID: 8188290) Koop B.F. … Hood L. (Genomics 1994) 2 3 64

Products for TRAV28 Gene

Sources for TRAV28 Gene

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