TRAV16 Gene protein-coding GIFtS : 17 GCID: GC14 P022819
T Cell Receptor Alpha Variable 16
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Aliasesfor TRAV16 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
10 fRNAdb ,
12 H-InvDB ,
13 NCBI ,
14 NONCODE ,
and/or 15 RNAdb )About This Section GeneCards Plus Aliases T Cell Receptor Alpha Variable 16 1 2 TCRAV16S12 TCRAV9S12
Export aliases for TRAV16 gene to outside databases Previous GC identifers: GC14U990304 GC14P020448 GC14P021529 GC14P021530 GC14P022459 GC14P022704
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Summariesfor TRAV16 gene (According to Entrez Gene ,
GeneCards ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section GeneCards Plus GeneCards Summary for TRAV16 Gene: TRAV16 (T cell receptor alpha variable 16) is a protein-coding gene. An important paralog of this gene is TRAV8-7 .
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Genomic Viewsfor TRAV16 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,miRBase ,UCSC (hg19) and
Ensembl (release 75) ,
Regulatory elements and Epigenetics data according to
QIAGEN , and/or
SwitchGear Genomics )About This Section GeneCards Plus Regulatory elements: Search for regulatory transcription factor binding sites for TRAV16 Other transcription factors Search Chromatin IP Primers for TRAV16 Epigenetics: DNA Methylation CpG Assay Predesigned for Pyrosequencing in human mouse rat
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 14q11 Ensembl cytogenetic band: 14q11.2 HGNC cytogenetic band: 14q11.2 TRAV16 Gene in genomic location: bands according to Ensembl, locations according to
Entrez Gene Ensembl GeneLoc information about chromosome 14 GeneLoc Exon Structure
GeneLoc location for GC14P022819: view genomic region
(about GC identifiers )
Start: 22,458,735 bp from pter End:
22,459,177 bp from pter
Size: 443 bases Orientation:
plus strand
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Proteinsfor TRAV16 gene
(According to
1 UniProtKB ,
HORDE ,
2 neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to PhosphoSitePlus ,
Specific Peptides from DME ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Cloud-Clone Corp. ,
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Cloud-Clone Corp. ,
Antibodies by
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
LSBio ,
Abcam , and/or
Cloud-Clone Corp. )
About This Section GeneCards Plus UniProtKB: --ENSEMBL proteins: ENSP00000451359 TRAV16 Human Recombinant
Protein Products: TRAV16 Antibody
Products: TRAV16 Assay Products:
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Domains /for TRAV16 gene (According to HGNC , IUPHAR , InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section GeneCards Plus HGNC Gene Families: TRAS: T cell receptors / TRA locus
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Functionfor TRAV16 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
genOway ,
QIAGEN
and/or HOMER ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
SwitchGear Genomics ,
Gene Editing from DNA2.0 ,
Clones from OriGene ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
ESI BIO ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene .)
About This Section GeneCards Plus Gene Ontology (GO): 1 molecular function term : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0005515 protein binding
-- --
About GeneDecksing Animal Models: Inhib. RNA Browse OriGene RNAi Predesigned siRNA for gene silencing in human mouse rat
Cell Line GenScript Custom overexpressing Cell Line Services for TRAV16 Browse ESI BIO Cell Lines and PureStem Progenitors for TRAV16 In Situ AssayAdvanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRAV16
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Localizationfor TRAV16 gene
(According to UniProtKB , COMPARTMENTS Subcellular localization database ,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene .)
About This Section GeneCards Plus
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Pathways & Interactionsfor TRAV16 gene
(SuperPaths according to PathCards ,
Pathways according to
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Sino Biological ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
QIAGEN ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Apr 2014 via
Entrez Gene) .
About This Section GeneCards Plus Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for TRAV16 Interactions: Search GeneGlobe Interaction Network for TRAV16
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Drugs & Compoundsfor TRAV16 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience ,
ApexBio ,
HMDB ,
BitterDB , and/or
Novoseek ,
Ligands according to IUPHAR ,
and Drugs according to DrugBank ,
Enzo Life Sciences , and/or
PharmGKB )
About This Section GeneCards Plus Browse compounds at ApexBio Browse Tocris compounds for TRAV16
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Transcriptsfor TRAV16 gene (Secondary structures according to
fRNAdb ,Unigene
(Build 236 Homo sapiens; Apr 25 2013) or GenBank , Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC , KenesGroup ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
SwitchGear Genomics ,
OriGene ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene , and/or
QIAGEN
)About This Section GeneCards Plus 1 Ensembl transcript including schematic representation, and UCSC links where relevant : ENST00000390444 (uc001wco.3 ) Inhib. RNA Browse OriGene RNAi Predesigned siRNA for gene silencing in human mouse rat
1 AceView cDNA sequence :
AW873544 GeneLoc Exon Structure
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Expression for TRAV16 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
Protein expression images according to data from SPIRE 1 MOPED ,
2 PaxDb , and 3 MaxQB ,
plus additional links to
SOURCE , and/or
BioGPS , and/or
UniProtKB ,QIAGEN ,
Primers from
OriGene , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section GeneCards Plus TRAV16 expression in normal human tissues
(normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS 2/3 CGAP TAG: -- About this image
TRAV16 Protein expression data from MOPED1 2 3 : Custom PCR Arrays for TRAV16 Primer Browse OriGene qPCR Search Pre-validated RT2 qPCR
Primer Assays in human, mouse, rat TRAV16 QuantiTect SYBR Green Assays in human mouse rat QuantiFast Probe-based Assays in human mouse rat In Situ Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRAV16
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Orthologsfor TRAV16 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section GeneCards Plus Orthologs for TRAV16 gene from Selected species (see all 4 ) About this table
Species with no ortholog for TRAV16 ENSEMBL Gene Tree for TRAV16 (if available)TreeFam Gene Tree for TRAV16 (if available)
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Paralogsfor TRAV16 gene (Paralogs according to
1 HomoloGene ,2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section GeneCards Plus Paralogs for TRAV16 gene TRAV8-7 2 TRAV9-1 2 TRAV8-3 2 TRAV8-6 2 TRAV8-4 2 TRAV3 2 TRAV8-1 2 TRAV40 2 TRAV8-2 2 TRAV18 2 TRAV9-2 2 About GeneDecksing
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Genomic Variantsfor TRAV16 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
4 UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) , the Human Cytochrome P450 Allele
Nomenclature Database , and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN )
About This Section GeneCards Plus Site Specific Mutation Identification with PCR Assays
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Disorders
/ Diseasesfor TRAV16 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database , Conferences by KenesGroup ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section GeneCards Plus
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Publicationsfor TRAV16 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section GeneCards Plus PubMed article for TRAV16 gene integrated from 10 sources :(articles sorted by number of sources associating them with TRAV16) Utopia : connect your pdf to the dynamic
The human T-cell receptor TCRAC/TCRDC (C alpha/C delta) region: organization, sequence, and evolution of 97.6 kb of DNA. (PubMed id 8188290) 1 , 3(Genomics 1994)
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External Searches for TRAV16 gene (in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section GeneCards Plus
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Genome Databases showing TRAV16 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section GeneCards Plus
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Other Databases showing TRAV16 gene
(According to HUGE )
About This Section GeneCards Plus --
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Specialized Databases showing TRAV16 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , UniProtKB/TrEMBL , and/or others, e.g. Wikipedia and GeneReviews , via UniProtKB/Swiss-Prot )About This Section GeneCards Plus
Name Description PharmGKB entry for TRAV16 Pharmacogenomics, SNPs, Pathways IMGT entry for TRAV16The international I mM unoG eneT ics information system® specializing in Immunoglobulins (IG), T cell receptors (TR), Major Histocompatibility Complex (MHC) and related proteins of the immune system (RPI) of human and other vertebrate species.
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About This Section GeneCards Plus Patent Information for TRAV16 gene: TRAV16 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor TRAV16 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Cloud-Clone Corp. , Thermo Fisher Scientific , LSBio , Gene Editing from DNA2.0 . Clones from OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , and ESI BIO , PCR Arrays from QIAGEN , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , Enzo Life Sciences , and/or
ApexBio , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory ,
genOway )About This Section GeneCards Plus
Block miRNA regulation of human, mouse, rat TRAV16 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing TRAV16 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human mouse rat Predesigned siRNA for gene silencing in human mouse rat QuantiFast Probe-based Assays in human mouse rat QuantiTect SYBR Green Assays in human mouse rat Custom PCR Arrays for TRAV16 Search Chromatin IP Primers for TRAV16 Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat TRAV16 Search GeneGlobe Interaction Network for TRAV16 Search Regulatory tfbs for TRAV16
Search Tocris compounds for TRAV16
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for TRAV16
Search ThermoFisher Antibodies for TRAV16
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TRAV16
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Genomic Views for TRAV16
Intellectual Property for TRAV16
Localization for TRAV16
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Pathways / Interactions for TRAV16
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