TRAV12-2 Gene
protein-coding GIFtS : 20
GCID: GC14 P022357
T cell receptor alpha variable 12-2
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Aliasesfor TRAV12-2 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases T Cell Receptor Alpha Variable 12-2 1 2 TCRAV12S22 TCRAV2S12 TRAV1222
Export aliases for TRAV12-2 gene to outside databases Previous GC identifers: GC14U990310 GC14P020347 GC14P020348 GC14P021425
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Summariesfor TRAV12-2 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
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Genomic Viewsfor TRAV12-2 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000014.8 NC_018925.1 NT_026437.12 Regulatory elements: Search SABiosciences Regulatory transcription factor binding sites for TRAV12-2 Other transcription factors Search SABiosciences Chromatin IP Primers for TRAV12-2 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRAV12-2
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 14q11 Ensembl cytogenetic band: 14q11.2 HGNC cytogenetic band: 14q11.2 TRAV12-2 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 14 GeneLoc Exon Structure
GeneLoc location for GC14P022357: view genomic region
(about GC identifiers )
Start:
22,356,037 bp from pter
End:
22,356,682 bp from pter
Size:
646 bases
Orientation:
plus strand
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Proteinsfor TRAV12-2 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB: --TRAV12-2 Protein expression data from MOPED and PaxDb : --ENSEMBL proteins: ENSP00000437362 Human Recombinant Protein Products for TRAV12-2: Antibody Products for TRAV12-2: Assay Products for TRAV12-2:
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Protein
Domains / Familiesfor TRAV12-2 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
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Functionfor TRAV12-2 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory ,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase ,
shRNA from
OriGene ,
Sirion Biotech ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Sirion Biotech ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
Sirion Biotech ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Animal Models:
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Pathways & Interactionsfor TRAV12-2 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for TRAV12-2
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Drugs & Compoundsfor TRAV12-2 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for TRAV12-2 Search CenterWatch for drugs/clinical trials and news about TRAV12-2
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Transcriptsfor TRAV12-2 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
Sirion Biotech ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section Unigene Cluster for TRAV12-2:
T cell receptor alpha variable 12-2 Hs.546374 [show with all ESTs ] Unigene Representative Sequence: AB305679 1 Ensembl transcript including schematic representation, and UCSC links where relevant : ENST00000390437 (uc021rph.1 uc010aiv.1 ) Additional cDNA sequence: AB305679.1 AB305703.1 AB305705.1 AB305730.1 AB305739.1 AB305742.1 AB306021.1 AB306068.1 AB306105.1 AB306116.1 AB360829.1 AF020639.1 AF020651.1 AF327017.1 AF532837.1 AF532838.1 AF532839.1 AF532840.1 AF532841.1 AF532842.1 AF532843.1 AF532844.1 AF532845.1 AF532846.1 AF532847.1 AF532848.1 AF532849.1 AF532850.1 AF532851.1 AF532852.1 AF532853.1 AF532854.1 AF532855.1 AF532856.1 AY135832.1 AY135833.1 AY135834.1 AY135835.1 AY135836.1 AY135837.1 AY135838.1 AY135839.1 AY135840.1 AY135841.1 AY135842.1 AY135843.1 AY135844.1 AY135845.1 AY135846.1 AY135847.1 AY135848.1 AY135849.1 AY135850.1 AY135851.1 AY135852.1 AY135853.1 AY247836.1 L34698.1 M17652.1 M17653.1 M27369.1 M81774.1 S60781.1 S82064.1 S82066.1 U39107.1 U40463.1 U40464.1 U40776.1 X04940.1 X04946.1 X58746.1 X92766.1 X92783.1 X92883.1
15 DOTS entries : DT.96086681 DT.96086679 DT.100028642 DT.120744026 DT.95303337 DT.120743854 DT.100028648 DT.100001535
DT.120744102 DT.95236306 DT.100028649 DT.120744328 DT.95070986 DT.95106187 DT.99927246 GeneLoc Exon Structure
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Expression for TRAV12-2 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section TRAV12-2 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: AGAGACTCCCAbout this image Genevestigator expression for TRAV12-2 SOURCE GeneReport for Unigene cluster: Hs.546374 SABiosciences Custom PCR Arrays for TRAV12-2
Primer Products: Browse OriGene genome-wide validated SYBR primer pairs Browse OriGene validated miRNA SYBR primer pairs Search SABiosciences RT2 qPCR
Primer Assays in human, mouse, rat TRAV12-2 Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRAV12-2 Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRAV12-2
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Orthologsfor TRAV12-2 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
--
ENSEMBL Gene Tree for TRAV12-2 (if available)TreeFam Gene Tree for TRAV12-2 (if available)
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Paralogsfor TRAV12-2 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for TRAV12-2 gene TRAV34 2 TRAV24 2 TRAV21 2 TRAV41 2 TRAV12-3 2 TRAV6 2 TRAV22 2 TRAV7 2 TRAV12-1 2 TRAV17 2 TRAV23DV6 2 TRAV25 2 TRAV13-2 2 TRAV30 2 TRAV20 2 TRAV10 2 TRAV29DV5 2 TRAV27 2 TRAV13-1 2 TRAV35 2 TRAV5 2 TRAV36DV7 2 TRAV39 2
TRAV12-2 for paralogs About GeneDecksing
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Genomic Variantsfor TRAV12-2 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section SABiosciences Cancer Mutation PCR Assays
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Disorders
/ Diseasesfor TRAV12-2 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
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Publicationsfor TRAV12-2 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for TRAV12-2 gene integrated from 9 sources : (articles sorted by number of sources associating them with TRAV12-2) Utopia : connect your pdf to the dynamic world of online information
The human T-cell receptor TCRAC/TCRDC (C alpha/C delta) region: organization, sequence, and evolution of 97.6 kb of DNA. (PubMed id 8188290) 1 , 3 Koop B.F.... Hood L. (1994) Comprehensive analysis of the functional TCR repertoi re at the single-cell level. (PubMed id 18191637) 1 Ozawa T....Muraguchi A. (2008)
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External Searches for TRAV12-2 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing TRAV12-2 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing TRAV12-2 gene
(According to HUGE )
About This Section --
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Specialized Databases showing TRAV12-2 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for TRAV12-2 Pharmacogenomics, SNPs, Pathways IMGT entry for TRAV12-2 The international I mM unoG eneT ics information system® specializing in Immunoglobulins (IG), T cell receptors (TR), Major Histocompatibility Complex (MHC) and related proteins of the immune system (RPI) of human and other vertebrate species.
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About This Section Patent Information for TRAV12-2 gene: Search GeneIP for patents involving TRAV12-2 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor TRAV12-2 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 and Sirion Biotech , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript , LifeMap BioReagents , and Sirion Biotech , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences , In Situ Hybridization Assays from Advanced Cell Diagnostics , Animal models from inGenious Targeting Laboratory )About This Section
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat TRAV12-2 Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing TRAV12-2 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat TRAV12-2 Search QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat TRAV12-2 Search QIAGEN QuantiFast Probe-based Assays in human, mouse, rat TRAV12-2 Search QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat TRAV12-2
Search ThermoFisher Antibodies for TRAV12-2
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat TRAV12-2
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Genomic Views for TRAV12-2
Intellectual Property for TRAV12-2
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